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Volumn 139, Issue 1-2, 2003, Pages 47-57

Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome

Author keywords

Brain derived neurotrophic factor; Down syndrome; NGF; Radial arm maze; Reference memory; Ts65Dn; Working memory

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN PROTEIN; NERVE GROWTH FACTOR;

EID: 0037450168     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-4328(02)00082-7     Document Type: Article
Times cited : (132)

References (59)
  • 2
    • 0033762841 scopus 로고    scopus 로고
    • BDNF protects against spatial memory deficits following neonatal hypoxia-ischemia
    • Almli C., Levy T., Hee Han B., Shah A., Gidday J., Holtzman D. BDNF protects against spatial memory deficits following neonatal hypoxia-ischemia. Exp. Neurol. 166:2000;99-114.
    • (2000) Exp. Neurol. , vol.166 , pp. 99-114
    • Almli, C.1    Levy, T.2    Hee Han, B.3    Shah, A.4    Gidday, J.5    Holtzman, D.6
  • 3
    • 0029843679 scopus 로고    scopus 로고
    • Systemic administration of a nerve growth factor conjugate reverses age-related cognitive dysfunction and prevents cholinergic neuron atrophy
    • Backman C., Rose G.M., Hoffer B.J., Henry M.A., Bartus R.T., Friden P., et al. Systemic administration of a nerve growth factor conjugate reverses age-related cognitive dysfunction and prevents cholinergic neuron atrophy. J. Neurosci. 16:1996;5437-5442.
    • (1996) J. Neurosci. , vol.16 , pp. 5437-5442
    • Backman, C.1    Rose, G.M.2    Hoffer, B.J.3    Henry, M.A.4    Bartus, R.T.5    Friden, P.6
  • 4
    • 0345557871 scopus 로고    scopus 로고
    • Carrier mediated delivery of NGF; Alterations in basal forebrain neurons in aged rats revealed using antibodies against low and high affinity NGF receptors
    • Backman C., Rose G.M., Bartus R.T., Hoffer B.J., Mufson E.J., Granholm A.-Ch. Carrier mediated delivery of NGF; Alterations in basal forebrain neurons in aged rats revealed using antibodies against low and high affinity NGF receptors. J. Comp. Neurol. 387:1997;1-11.
    • (1997) J. Comp. Neurol. , vol.387 , pp. 1-11
    • Backman, C.1    Rose, G.M.2    Bartus, R.T.3    Hoffer, B.J.4    Mufson, E.J.5    Granholm, A.-Ch.6
  • 5
    • 0033826237 scopus 로고    scopus 로고
    • In two species, females exhibit superior working memory and inferior reference memory on the water radial-arm maze
    • Bimonte H., Hyde L., Hoplight B., Denenberg V. In two species, females exhibit superior working memory and inferior reference memory on the water radial-arm maze. Physiol. Behav. 70:2000;311-317.
    • (2000) Physiol. Behav. , vol.70 , pp. 311-317
    • Bimonte, H.1    Hyde, L.2    Hoplight, B.3    Denenberg, V.4
  • 6
    • 0037213030 scopus 로고    scopus 로고
    • Age-related deficits as working memory load increases: Relationships with growth factors
    • in press
    • Bimonte HB, Nelson ME, Granholm A-Ch. Age-related deficits as working memory load increases: relationships with growth factors, in press, Neurobiology of Aging.
    • Neurobiology of Aging
    • Bimonte, H.B.1    Nelson, M.E.2    Granholm, A.-Ch.3
  • 8
    • 0028273064 scopus 로고
    • Cognitive impairment in adults with Down's syndrome: Similarities to early cognitive changes in Alzheimer's disease
    • Brugge K.L., Nichols S.L., Salmon D.P., Hill L.R., Delis D.C., Aaron L., et al. Cognitive impairment in adults with Down's syndrome: similarities to early cognitive changes in Alzheimer's disease. Neurology. 44:(2):1994;232-238.
    • (1994) Neurology , vol.44 , Issue.2 , pp. 232-238
    • Brugge, K.L.1    Nichols, S.L.2    Salmon, D.P.3    Hill, L.R.4    Delis, D.C.5    Aaron, L.6
  • 10
    • 0030658839 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor is reduced in Alzheimer's disease
    • Conner B., Young D., Yan Q., Faull R.L., Synek B., Dragunow M. Brain-derived neurotrophic factor is reduced in Alzheimer's disease. Mol. Brain Res. 49:(1-2):1997;71-81.
    • (1997) Mol. Brain Res. , vol.49 , Issue.1-2 , pp. 71-81
    • Conner, B.1    Young, D.2    Yan, Q.3    Faull, R.L.4    Synek, B.5    Dragunow, M.6
  • 11
    • 2942591228 scopus 로고    scopus 로고
    • Failed retrograde transport of NGF in a mouse model of Down's Syndrome: Reversal of cholinergic neurodegenerative phenotypes following NGF infusion
    • Cooper J.D., Salehi A., Delcroix J.-D., Howe C.L., Belichenko P.V., Chua-Couzens J., et al. Failed retrograde transport of NGF in a mouse model of Down's Syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion. Proc. Natl. Acad. Sci. USA. 98:2001;10439-10444.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 10439-10444
    • Cooper, J.D.1    Salehi, A.2    Delcroix, J.-D.3    Howe, C.L.4    Belichenko, P.V.5    Chua-Couzens, J.6
  • 12
    • 0030045921 scopus 로고    scopus 로고
    • Behavioral assessment of the Ts65Dn mouse, a model for down syndrome: Altered behavior in the elevated plus maze and open field
    • Coussons-Read M.E., Crnic L.S. Behavioral assessment of the Ts65Dn mouse, a model for down syndrome: altered behavior in the elevated plus maze and open field. Behav. Genet. 26:(1):1996;7-13.
    • (1996) Behav. Genet. , vol.26 , Issue.1 , pp. 7-13
    • Coussons-Read, M.E.1    Crnic, L.S.2
  • 13
    • 0033407499 scopus 로고    scopus 로고
    • Motor dysfunction in a mouse model for down syndrome
    • Costa A.C.S., Walsh K., Davisson M.T. Motor dysfunction in a mouse model for down syndrome. Physiol. Behav. 68:1999;211-220.
    • (1999) Physiol. Behav. , vol.68 , pp. 211-220
    • Costa, A.C.S.1    Walsh, K.2    Davisson, M.T.3
  • 14
    • 0021646405 scopus 로고
    • Neurotransmitter specific alterations in dementing disorders: Insights from animal models
    • Coyle J.T., Singer H., McKinney M., Price D. Neurotransmitter specific alterations in dementing disorders: insights from animal models. J. Psych. Res. 18:1984;501-512.
    • (1984) J. Psych. Res. , vol.18 , pp. 501-512
    • Coyle, J.T.1    Singer, H.2    McKinney, M.3    Price, D.4
  • 15
    • 0003043137 scopus 로고    scopus 로고
    • Contributions of mouse models to understanding Down's syndrome
    • Crnic L.S., Pennington B.F. Contributions of mouse models to understanding Down's syndrome. Prog. Infancy Res. 1:2000;69-111.
    • (2000) Prog. Infancy Res. , vol.1 , pp. 69-111
    • Crnic, L.S.1    Pennington, B.F.2
  • 16
    • 0030605498 scopus 로고    scopus 로고
    • The neurotrophic hypothesis: Where does it stand?
    • Review
    • Davies A.M. The neurotrophic hypothesis: where does it stand? Review Philos. Trans. R. Soc. Lond., Ser. B: Biol. Sci. 351:(1338):1996;389-394.
    • (1996) Philos. Trans. R. Soc. Lond., Ser. B: Biol. Sci. , vol.351 , Issue.1338 , pp. 389-394
    • Davies, A.M.1
  • 17
    • 0025663975 scopus 로고
    • Segmental trisomy of murine chromosome 16: A new model system for studying Down syndrome
    • Davisson M.T., Schmidt C., Akeson E.C. Segmental trisomy of murine chromosome 16: a new model system for studying Down syndrome. Prog. Clin. Biol. Res. 360:1990;263-280.
    • (1990) Prog. Clin. Biol. Res. , vol.360 , pp. 263-280
    • Davisson, M.T.1    Schmidt, C.2    Akeson, E.C.3
  • 19
    • 0031890117 scopus 로고    scopus 로고
    • Impaired spatial working and reference memory in segmental trisomy (Ts65Dn) mice
    • Demas G.E., Nelson R.J., Krueger B.K., Yarowsky P.J. Impaired spatial working and reference memory in segmental trisomy (Ts65Dn) mice. Behav. Brain Res. 90:1998;199-211.
    • (1998) Behav. Brain Res. , vol.90 , pp. 199-211
    • Demas, G.E.1    Nelson, R.J.2    Krueger, B.K.3    Yarowsky, P.J.4
  • 21
    • 0031214428 scopus 로고    scopus 로고
    • Nerve growth factor attenuates cholinergic deficits following traumatic brain injury in rats
    • Dixon C.E., Flinn P., Bao J., Venya R., Hayes R.L. Nerve growth factor attenuates cholinergic deficits following traumatic brain injury in rats. Exp. Neurobiol. 146:1997;479-490.
    • (1997) Exp. Neurobiol. , vol.146 , pp. 479-490
    • Dixon, C.E.1    Flinn, P.2    Bao, J.3    Venya, R.4    Hayes, R.L.5
  • 22
    • 0015965912 scopus 로고
    • Human memory and the cholinergic system
    • Drachman D., Leavitt J. Human memory and the cholinergic system. Arch. Neurol. 30:1974;113-121.
    • (1974) Arch. Neurol. , vol.30 , pp. 113-121
    • Drachman, D.1    Leavitt, J.2
  • 24
    • 0025938955 scopus 로고
    • NGF improves spatial memory in aged rodents as a function of age
    • Fischer W., Bjorklund A., Chen K., Gage F.H. NGF improves spatial memory in aged rodents as a function of age. J. Neurosci. 11:(7):1991;1889-1906.
    • (1991) J. Neurosci. , vol.11 , Issue.7 , pp. 1889-1906
    • Fischer, W.1    Bjorklund, A.2    Chen, K.3    Gage, F.H.4
  • 25
    • 0023643241 scopus 로고
    • Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor
    • Fischer W., Wictorin K., Bjorklund A., Williams L.R., Varon S., Gage F.H. Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor. Nature. 329:(3):1987;65-68.
    • (1987) Nature , vol.329 , Issue.3 , pp. 65-68
    • Fischer, W.1    Wictorin, K.2    Bjorklund, A.3    Williams, L.R.4    Varon, S.5    Gage, F.H.6
  • 26
    • 0035022091 scopus 로고    scopus 로고
    • On the cause of mental retardation in Down syndrome: Extrapolation from full and segmental trisomy 16 mouse models
    • Galdzicki Z., Siarey R., Pearce R., Stoll J., Rapoport S. On the cause of mental retardation in Down syndrome: extrapolation from full and segmental trisomy 16 mouse models. Brain Res. Revs. 35:2001;115-145.
    • (2001) Brain Res. Revs. , vol.35 , pp. 115-145
    • Galdzicki, Z.1    Siarey, R.2    Pearce, R.3    Stoll, J.4    Rapoport, S.5
  • 27
    • 0034097607 scopus 로고    scopus 로고
    • Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome
    • Granholm A.-Ch., Sanders L.A., Crnic L.S. Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome. Exp. Neurol. 161:2000;647-663.
    • (2000) Exp. Neurol. , vol.161 , pp. 647-663
    • Granholm, A.-Ch.1    Sanders, L.A.2    Crnic, L.S.3
  • 29
    • 0033594185 scopus 로고    scopus 로고
    • Evidence that nerve growth factor influences recent memory through structural changes in septohippocampal cholinergic neurons
    • Gustilo M.C., Markowska A.L., Breckler S.J., Fleischsman C.A., Price D.L., Koliatsos V.E. Evidence that nerve growth factor influences recent memory through structural changes in septohippocampal cholinergic neurons. J. Comp. Neurol. 405:1999;491-507.
    • (1999) J. Comp. Neurol. , vol.405 , pp. 491-507
    • Gustilo, M.C.1    Markowska, A.L.2    Breckler, S.J.3    Fleischsman, C.A.4    Price, D.L.5    Koliatsos, V.E.6
  • 30
    • 0035029836 scopus 로고    scopus 로고
    • Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down's syndrome
    • Head E., Azizeh B.Y., Lott I.T., Tenner A.J., Cotman C.W., Cribbs D.H. Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down's syndrome. Neurobiol. Dis. 8:2001;252-265.
    • (2001) Neurobiol. Dis. , vol.8 , pp. 252-265
    • Head, E.1    Azizeh, B.Y.2    Lott, I.T.3    Tenner, A.J.4    Cotman, C.W.5    Cribbs, D.H.6
  • 31
    • 0034087784 scopus 로고    scopus 로고
    • Regions-specific neurotrophin imbalances in Alzheimer's disease: Decreased levels of BDNF and increased levels of NGF in hippocampal and cortical areas
    • Hock C., Heese K., Hulette C., Oten U. Regions-specific neurotrophin imbalances in Alzheimer's disease: decreased levels of BDNF and increased levels of NGF in hippocampal and cortical areas. Arch. Neurol. 57:(6):2000;846-851.
    • (2000) Arch. Neurol. , vol.57 , Issue.6 , pp. 846-851
    • Hock, C.1    Heese, K.2    Hulette, C.3    Oten, U.4
  • 33
    • 0027742330 scopus 로고
    • Nerve growth factor reverses neuronal atrophy in a down syndrome model of age-related neurodegeneration
    • Holtzman D.M., Li Y., Chen K., Gage F.H., Epstein C.J., Mobley W.C. Nerve growth factor reverses neuronal atrophy in a down syndrome model of age-related neurodegeneration. Neurology. 43:1993;2668-2673.
    • (1993) Neurology , vol.43 , pp. 2668-2673
    • Holtzman, D.M.1    Li, Y.2    Chen, K.3    Gage, F.H.4    Epstein, C.J.5    Mobley, W.C.6
  • 34
    • 0035825304 scopus 로고    scopus 로고
    • Ts65Dn mice, a model for Down syndrome, have deficits in context discrimination learning suggesting impaired hippocampal function
    • Hyde L.A., Frisone D.F., Crnis L.S. Ts65Dn mice, a model for Down syndrome, have deficits in context discrimination learning suggesting impaired hippocampal function. Behav. Brain Res. 118:2001;53-60.
    • (2001) Behav. Brain Res. , vol.118 , pp. 53-60
    • Hyde, L.A.1    Frisone, D.F.2    Crnis, L.S.3
  • 35
    • 0032473584 scopus 로고    scopus 로고
    • Water version of the radial-arm maze: Learning in three inbred strains of mice
    • Hyde L.A., Hoplight B.J., Denenberg V.H. Water version of the radial-arm maze: learning in three inbred strains of mice. Brain Res. 785:(2):1998;236-244.
    • (1998) Brain Res. , vol.785 , Issue.2 , pp. 236-244
    • Hyde, L.A.1    Hoplight, B.J.2    Denenberg, V.H.3
  • 36
    • 0034725155 scopus 로고    scopus 로고
    • Non-spatial water radial-arm maze learning in mice
    • Hyde L., Sherman G., Denenberg V. Non-spatial water radial-arm maze learning in mice. Brain Res. 863:2000;151-159.
    • (2000) Brain Res. , vol.863 , pp. 151-159
    • Hyde, L.1    Sherman, G.2    Denenberg, V.3
  • 37
    • 0021687512 scopus 로고
    • On the role of hippocampal connections in the performance of place and cue tasks: Comparisons with damage to hippocampus
    • Jarrard L., Okaichi H., Steward O., Goldschmidt R. On the role of hippocampal connections in the performance of place and cue tasks: comparisons with damage to hippocampus. Behav. Neurosci. 98:(6):1984;946-954.
    • (1984) Behav. Neurosci. , vol.98 , Issue.6 , pp. 946-954
    • Jarrard, L.1    Okaichi, H.2    Steward, O.3    Goldschmidt, R.4
  • 38
    • 0030271334 scopus 로고    scopus 로고
    • Characterization of sensorimotor performance, reproductive and aggressive behaviors in segmental trisomic 16 (Ts65Dn) mice
    • Klein S.L., Kriegsfeld L.J., Hairston J.E., Rau V., Nelson R.J., Yarowsky P.J. Characterization of sensorimotor performance, reproductive and aggressive behaviors in segmental trisomic 16 (Ts65Dn) mice. Physio. Behav. 60:(4):1996;1159-1164.
    • (1996) Physio. Behav. , vol.60 , Issue.4 , pp. 1159-1164
    • Klein, S.L.1    Kriegsfeld, L.J.2    Hairston, J.E.3    Rau, V.4    Nelson, R.J.5    Yarowsky, P.J.6
  • 40
    • 0031748674 scopus 로고    scopus 로고
    • A role for BDNF in the late-phase of hippocampal long-term potentiation
    • Korte M., Kang H., Bonhoeffer T., Schuman E. A role for BDNF in the late-phase of hippocampal long-term potentiation. Neuropharmacology. 37:1998;553-559.
    • (1998) Neuropharmacology , vol.37 , pp. 553-559
    • Korte, M.1    Kang, H.2    Bonhoeffer, T.3    Schuman, E.4
  • 41
    • 0033970177 scopus 로고    scopus 로고
    • Synaptic deficit in the temporal cortex of partial trisomy 16 (Ts65Dn) mice
    • Kurt M.A., Davies D.C., Kidd M., Dierssen M., Florez J. Synaptic deficit in the temporal cortex of partial trisomy 16 (Ts65Dn) mice. Brain Res. 858:2000;191-197.
    • (2000) Brain Res. , vol.858 , pp. 191-197
    • Kurt, M.A.1    Davies, D.C.2    Kidd, M.3    Dierssen, M.4    Florez, J.5
  • 42
    • 0031898636 scopus 로고    scopus 로고
    • The cognitive psychopharmacology of Alzheimer's disease: Focus on cholinergic systems
    • Lawrence A.D., Sahakian B.J. The cognitive psychopharmacology of Alzheimer's disease: focus on cholinergic systems. Neurochem. Res. 23:1998;787-794.
    • (1998) Neurochem. Res. , vol.23 , pp. 787-794
    • Lawrence, A.D.1    Sahakian, B.J.2
  • 43
    • 0032213168 scopus 로고    scopus 로고
    • Neurotrophin-dependent modulation of glutamatergic synaptic transmission in the mammalian CNS
    • LeBmann V. Neurotrophin-dependent modulation of glutamatergic synaptic transmission in the mammalian CNS. Gen. Pharmacol. 31:(5):1998;667-674.
    • (1998) Gen. Pharmacol. , vol.31 , Issue.5 , pp. 667-674
    • LeBmann, V.1
  • 44
    • 0023236055 scopus 로고
    • The nerve growth factor 35 years later
    • Levi-Montalcini R. The nerve growth factor 35 years later. Science. 237:1987;1154-1162.
    • (1987) Science , vol.237 , pp. 1154-1162
    • Levi-Montalcini, R.1
  • 45
    • 0024503377 scopus 로고
    • The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with down's Syndrome
    • Mann D.M., Esiri M.M. The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with down's Syndrome. J. Neurol. Sci. 89:1989;169-179.
    • (1989) J. Neurol. Sci. , vol.89 , pp. 169-179
    • Mann, D.M.1    Esiri, M.M.2
  • 46
    • 0027933176 scopus 로고
    • Human nerve growth factor improves spatial memory in aged but not in young rats
    • Markowska A.L., Koliatsos V.E., Breckler S.J., Price D.L., Olton D.S. Human nerve growth factor improves spatial memory in aged but not in young rats. J. Neurosci. 14:(8):1994;4815-4824.
    • (1994) J. Neurosci. , vol.14 , Issue.8 , pp. 4815-4824
    • Markowska, A.L.1    Koliatsos, V.E.2    Breckler, S.J.3    Price, D.L.4    Olton, D.S.5
  • 47
    • 0030709340 scopus 로고    scopus 로고
    • Cholinergic, serotonergic, and catecholaminergic neurons are not affected in Ts65Dn mice
    • Megias M., Verduga R., Diersson M., Florez J., Insausti R., Crespo D. Cholinergic, serotonergic, and catecholaminergic neurons are not affected in Ts65Dn mice. Neuroreport. 8:1997;3475-3478.
    • (1997) Neuroreport , vol.8 , pp. 3475-3478
    • Megias, M.1    Verduga, R.2    Diersson, M.3    Florez, J.4    Insausti, R.5    Crespo, D.6
  • 48
    • 0030480907 scopus 로고    scopus 로고
    • Spatial working memory in patients with frontal lobe excisions
    • Miotto E., Bullock P., Polkey C., Morris R. Spatial working memory in patients with frontal lobe excisions. Cortex. 32:1996;613-630.
    • (1996) Cortex , vol.32 , pp. 613-630
    • Miotto, E.1    Bullock, P.2    Polkey, C.3    Morris, R.4
  • 49
    • 0034666119 scopus 로고    scopus 로고
    • Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats
    • Mizuno M., Yamada K., Olariu A., Nawa H., Nabeshima T. Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. J. Neurosci. 20:(18):2000;7116-7121.
    • (2000) J. Neurosci. , vol.20 , Issue.18 , pp. 7116-7121
    • Mizuno, M.1    Yamada, K.2    Olariu, A.3    Nawa, H.4    Nabeshima, T.5
  • 50
    • 0028969073 scopus 로고
    • Long-term estrogen replacement therapy in female patients with dementia of the Alzheimer type: 7 case reports
    • Ohkura T., Isse K., Akazawa K., Hamamoto M., Yaoi Y., Hagino N. Long-term estrogen replacement therapy in female patients with dementia of the Alzheimer type: 7 case reports. Dementia. 6:(2):1995;99-107.
    • (1995) Dementia , vol.6 , Issue.2 , pp. 99-107
    • Ohkura, T.1    Isse, K.2    Akazawa, K.3    Hamamoto, M.4    Yaoi, Y.5    Hagino, N.6
  • 51
    • 0025633723 scopus 로고
    • A further characterization of the spatial problem-solving deficit induced by lesions of the medial frontal cortex on the rat
    • Poucet B. A further characterization of the spatial problem-solving deficit induced by lesions of the medial frontal cortex on the rat. Behav. Brain Res. 41:1990a;229-237.
    • (1990) Behav. Brain Res. , vol.41 , pp. 229-237
    • Poucet, B.1
  • 52
    • 0025346907 scopus 로고
    • Septum and medial frontal cortex contribution to spatial problem-solving
    • Poucet B., Herrmann T. Septum and medial frontal cortex contribution to spatial problem-solving. Behav. Brain Res. 37:1990b;269-280.
    • (1990) Behav. Brain Res. , vol.37 , pp. 269-280
    • Poucet, B.1    Herrmann, T.2
  • 54
    • 0028348091 scopus 로고
    • Nerve growth factor increases extracellular acetylcholine levels in the parietal cortex and hippocampus of aged rats and restores object recognition
    • Scali C., Casamenti F., Pazzagli M., Bartolini L., Pepeu G. Nerve growth factor increases extracellular acetylcholine levels in the parietal cortex and hippocampus of aged rats and restores object recognition. Neurosci. Lett. 170:1994;117-120.
    • (1994) Neurosci. Lett. , vol.170 , pp. 117-120
    • Scali, C.1    Casamenti, F.2    Pazzagli, M.3    Bartolini, L.4    Pepeu, G.5
  • 55
    • 0033962469 scopus 로고    scopus 로고
    • Reduction in trkA immunoreactive neurons is not associated with an overexpression of galaninergic fibers within the nucleus basalis in Down's syndrome
    • Sendera D.J., Ma S.Y., Jaffar S., Kozlowski P.B., Kordower J.H., Mawal Y., et al. Reduction in trkA immunoreactive neurons is not associated with an overexpression of galaninergic fibers within the nucleus basalis in Down's syndrome. J. Neurochem. 74:2000;1185-1196.
    • (2000) J. Neurochem. , vol.74 , pp. 1185-1196
    • Sendera, D.J.1    Ma, S.Y.2    Jaffar, S.3    Kozlowski, P.B.4    Kordower, J.H.5    Mawal, Y.6
  • 56
    • 0031414807 scopus 로고    scopus 로고
    • Altered long-term potentiation in the young and old Ts65Dn mouse a model for Down syndrome
    • Siarey R.J., Stoll J., Rapoport S.I., Galdzicki Z. Altered long-term potentiation in the young and old Ts65Dn mouse a model for Down syndrome. Neuropharmacology. 36:1997;1549-1554.
    • (1997) Neuropharmacology , vol.36 , pp. 1549-1554
    • Siarey, R.J.1    Stoll, J.2    Rapoport, S.I.3    Galdzicki, Z.4
  • 57
    • 0021956826 scopus 로고
    • The cholinergic deficit in Alzheimer's disease
    • Wisnieski K.E., Wisnieski H.M., Wen G.Y. The cholinergic deficit in Alzheimer's disease. Ann. Neurol. 17:1985;278-282.
    • (1985) Ann. Neurol. , vol.17 , pp. 278-282
    • Wisnieski, K.E.1    Wisnieski, H.M.2    Wen, G.Y.3
  • 58
    • 0025941928 scopus 로고
    • Cholinergic systems in mammalian brain and spinal cord
    • Woolf N. Cholinergic systems in mammalian brain and spinal cord. Prog. Neurobiol. 37:1991;475-524.
    • (1991) Prog. Neurobiol. , vol.37 , pp. 475-524
    • Woolf, N.1
  • 59
    • 0021049766 scopus 로고
    • Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and Down's syndrome
    • Yates C.M., Simpson A., Gordon A.F., Maloney J., Allison Y., Ritchie I.M., et al. Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and Down's syndrome. Brain Res. 280:1983;119-126.
    • (1983) Brain Res. , vol.280 , pp. 119-126
    • Yates, C.M.1    Simpson, A.2    Gordon, A.F.3    Maloney, J.4    Allison, Y.5    Ritchie, I.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.