-
1
-
-
77954069495
-
Mechanisms of immune-mediated liver injury
-
Adams D.H., Ju C., Ramaiah S.K., Uetrecht J., Jaeschke H. Mechanisms of immune-mediated liver injury. Toxicological Sciences 2010, 115:307-321.
-
(2010)
Toxicological Sciences
, vol.115
, pp. 307-321
-
-
Adams, D.H.1
Ju, C.2
Ramaiah, S.K.3
Uetrecht, J.4
Jaeschke, H.5
-
2
-
-
0025051394
-
Comparison of in vitro and in vivo haemotoxic effects of aminoglutethimide and glutethimide
-
Ali H., Khalaf L., Nicholls P.J., Poole A. Comparison of in vitro and in vivo haemotoxic effects of aminoglutethimide and glutethimide. Toxicology In Vitro 1990, 4:381-383.
-
(1990)
Toxicology In Vitro
, vol.4
, pp. 381-383
-
-
Ali, H.1
Khalaf, L.2
Nicholls, P.J.3
Poole, A.4
-
3
-
-
33746646799
-
Propylthiouracil-induced autoimmune syndromes: two distinct clinical presentations with different course and management
-
Aloush V., Litinsky I., Caspi D., Elkayam O. Propylthiouracil-induced autoimmune syndromes: two distinct clinical presentations with different course and management. Seminars in Arthritis and Rheumatism 2006, 36:4-9.
-
(2006)
Seminars in Arthritis and Rheumatism
, vol.36
, pp. 4-9
-
-
Aloush, V.1
Litinsky, I.2
Caspi, D.3
Elkayam, O.4
-
4
-
-
49049089966
-
Synthesis and characterization of DNA adducts from the HIV reverse transcriptase inhibitor nevirapine
-
Antunes A.M., Duarte M.P., Santos P.P., da Costa G.G., Heinze T.M., Beland F.A., et al. Synthesis and characterization of DNA adducts from the HIV reverse transcriptase inhibitor nevirapine. Chemical Research in Toxicology 2008, 21:1443-1456.
-
(2008)
Chemical Research in Toxicology
, vol.21
, pp. 1443-1456
-
-
Antunes, A.M.1
Duarte, M.P.2
Santos, P.P.3
da Costa, G.G.4
Heinze, T.M.5
Beland, F.A.6
-
5
-
-
77952359731
-
Amino acid adduct formation by the nevirapine metabolite, 12-hydroxynevirapine-a possible factor in nevirapine toxicity
-
Antunes A.M., Godinho A.L., Martins I.L., Justino G.C., Beland F.A., Marques M.M. Amino acid adduct formation by the nevirapine metabolite, 12-hydroxynevirapine-a possible factor in nevirapine toxicity. Chemical Research in Toxicology 2010, 23:888-899.
-
(2010)
Chemical Research in Toxicology
, vol.23
, pp. 888-899
-
-
Antunes, A.M.1
Godinho, A.L.2
Martins, I.L.3
Justino, G.C.4
Beland, F.A.5
Marques, M.M.6
-
6
-
-
78649281814
-
Protein adducts as prospective biomarkers of nevirapine toxicity
-
Antunes A.M., Godinho A.L., Martins I.L., Oliveira M.C., Gomes R.A., Coelho A.V., et al. Protein adducts as prospective biomarkers of nevirapine toxicity. Chemical Research in Toxicology 2010, 23:1714-1725.
-
(2010)
Chemical Research in Toxicology
, vol.23
, pp. 1714-1725
-
-
Antunes, A.M.1
Godinho, A.L.2
Martins, I.L.3
Oliveira, M.C.4
Gomes, R.A.5
Coelho, A.V.6
-
7
-
-
0023815108
-
Mercuric chloride-induced autoimmunity in the brown Norway rat. Cellular kinetics and major histocompatibility complex antigen expression
-
Aten J., Bosman C.B., Rozing J., Stijnen T., Hoedemaeker P.J., Weening J.J. Mercuric chloride-induced autoimmunity in the brown Norway rat. Cellular kinetics and major histocompatibility complex antigen expression. American Journal of Pathology 1988, 133:127-138.
-
(1988)
American Journal of Pathology
, vol.133
, pp. 127-138
-
-
Aten, J.1
Bosman, C.B.2
Rozing, J.3
Stijnen, T.4
Hoedemaeker, P.J.5
Weening, J.J.6
-
8
-
-
0021827278
-
Propylthiouracil-induced immune-mediated disease in the cat
-
Aucoin D.P., Peterson M.E., Hurvitz A.I., Drayer D.E., Lahita R.G., Quimby F.W., et al. Propylthiouracil-induced immune-mediated disease in the cat. Journal of Pharmacology and Experimental Therapeutics 1985, 234:13-18.
-
(1985)
Journal of Pharmacology and Experimental Therapeutics
, vol.234
, pp. 13-18
-
-
Aucoin, D.P.1
Peterson, M.E.2
Hurvitz, A.I.3
Drayer, D.E.4
Lahita, R.G.5
Quimby, F.W.6
-
9
-
-
0023913640
-
Dose dependent induction of anti-native DNA antibodies in cats by propylthiouracil
-
Aucoin D.P., Rubin R.L., Peterson M.E., Reidenberg M.M., Drayer D.E., Hurvitz A.I., et al. Dose dependent induction of anti-native DNA antibodies in cats by propylthiouracil. Arthritis & Rheumatism 1988, 31:688-692.
-
(1988)
Arthritis & Rheumatism
, vol.31
, pp. 688-692
-
-
Aucoin, D.P.1
Rubin, R.L.2
Peterson, M.E.3
Reidenberg, M.M.4
Drayer, D.E.5
Hurvitz, A.I.6
-
10
-
-
0032750686
-
Cytokine regulation of a rodent model of mercuric chloride-induced autoimmunity
-
Bagenstose L.M., Salgame P., Monestier M. Cytokine regulation of a rodent model of mercuric chloride-induced autoimmunity. Environmental Health Perspectives 1999, 107(Suppl. 5):807-810.
-
(1999)
Environmental Health Perspectives
, vol.107
, Issue.SUPPL. 5
, pp. 807-810
-
-
Bagenstose, L.M.1
Salgame, P.2
Monestier, M.3
-
11
-
-
0035134608
-
Sex differences in nevirapine rash
-
Bersoff-Matcha S.J., Miller W.C., Aberg J.A., van Der Horst C., Hamrick H.J., Powderly W.G., et al. Sex differences in nevirapine rash. Clinical Infectious Diseases 2001, 32:124-129.
-
(2001)
Clinical Infectious Diseases
, vol.32
, pp. 124-129
-
-
Bersoff-Matcha, S.J.1
Miller, W.C.2
Aberg, J.A.3
van Der Horst, C.4
Hamrick, H.J.5
Powderly, W.G.6
-
12
-
-
54049115421
-
The heterozygous Sod2+/- mouse: modeling the mitochondrial role in drug toxicity
-
Boelsterli U.A., Hsiao C.J.J. The heterozygous Sod2+/- mouse: modeling the mitochondrial role in drug toxicity. Drug Discovery Today 2008, 13:982-988.
-
(2008)
Drug Discovery Today
, vol.13
, pp. 982-988
-
-
Boelsterli, U.A.1
Hsiao, C.J.J.2
-
13
-
-
0035063639
-
Halothane-induced liver injury in outbred guinea pigs: role of trifluoroacetylated protein adducts in animal susceptibility
-
Bourdi M., Amouzadeh H.R., Rushmore T.H., Martin J.L., Pohl L.R. Halothane-induced liver injury in outbred guinea pigs: role of trifluoroacetylated protein adducts in animal susceptibility. Chemical Research in Toxicology 2001, 14:362-370.
-
(2001)
Chemical Research in Toxicology
, vol.14
, pp. 362-370
-
-
Bourdi, M.1
Amouzadeh, H.R.2
Rushmore, T.H.3
Martin, J.L.4
Pohl, L.R.5
-
14
-
-
0036154452
-
Protection against acetaminophen-induced liver injury and lethality by interleukin 10: role of inducible nitric oxide synthase
-
Bourdi M., Masubuchi Y., Reilly T.P., Amouzadeh H.R., Martin J.L., George J.W., et al. Protection against acetaminophen-induced liver injury and lethality by interleukin 10: role of inducible nitric oxide synthase. Hepatology 2002, 35:289-298.
-
(2002)
Hepatology
, vol.35
, pp. 289-298
-
-
Bourdi, M.1
Masubuchi, Y.2
Reilly, T.P.3
Amouzadeh, H.R.4
Martin, J.L.5
George, J.W.6
-
15
-
-
84863734328
-
Development of an animal model of amodiaquine-induced liver injury
-
Cai P., Nakagawa T., Uetrecht J. Development of an animal model of amodiaquine-induced liver injury. The Toxicologist 2011, 120:90.
-
(2011)
The Toxicologist
, vol.120
, pp. 90
-
-
Cai, P.1
Nakagawa, T.2
Uetrecht, J.3
-
16
-
-
84863766094
-
Amodiaquine-induced liver toxicity in the rat
-
Cai P., Uetrecht J. Amodiaquine-induced liver toxicity in the rat. The Toxicologist 2009, 108:238.
-
(2009)
The Toxicologist
, vol.108
, pp. 238
-
-
Cai, P.1
Uetrecht, J.2
-
17
-
-
53549126339
-
Demonstration of the metabolic pathway responsible for nevirapine-induced skin rash
-
Chen J., Mannargudi B.M., Xu L., Uetrecht J. Demonstration of the metabolic pathway responsible for nevirapine-induced skin rash. Chemical Research in Toxicology 2008, 21:1862-1870.
-
(2008)
Chemical Research in Toxicology
, vol.21
, pp. 1862-1870
-
-
Chen, J.1
Mannargudi, B.M.2
Xu, L.3
Uetrecht, J.4
-
18
-
-
0030873387
-
Characterization of the humoral immune response and hepatotoxicity after multiple halothane exposures in guinea pigs
-
Chen M., Gandolfi J. Characterization of the humoral immune response and hepatotoxicity after multiple halothane exposures in guinea pigs. Drug Metabolism Reviews 1997, 29:103-122.
-
(1997)
Drug Metabolism Reviews
, vol.29
, pp. 103-122
-
-
Chen, M.1
Gandolfi, J.2
-
19
-
-
73349088732
-
A study of the specificity of lymphocytes in nevirapine-induced skin rash
-
Chen X., Tharmanathan T., Mannargudi B., Gou H., Uetrecht J.P. A study of the specificity of lymphocytes in nevirapine-induced skin rash. Journal of Pharmacology and Experimental Therapeutics 2009, 331:836-841.
-
(2009)
Journal of Pharmacology and Experimental Therapeutics
, vol.331
, pp. 836-841
-
-
Chen, X.1
Tharmanathan, T.2
Mannargudi, B.3
Gou, H.4
Uetrecht, J.P.5
-
20
-
-
80053289164
-
Toll-like receptors in acute liver injury and regeneration
-
Chen Y., Sun R. Toll-like receptors in acute liver injury and regeneration. International Immunopharmacology 2011, 10.1016/j.intimp.2011.1004.1023.
-
(2011)
International Immunopharmacology
-
-
Chen, Y.1
Sun, R.2
-
21
-
-
77952671411
-
Involvement of natural killer T cells in halothane-induced liver injury in mice
-
Cheng L., You Q., Yin H., Holt M.P., Ju C. Involvement of natural killer T cells in halothane-induced liver injury in mice. Biochemical Pharmacology 2010, 80:255-261.
-
(2010)
Biochemical Pharmacology
, vol.80
, pp. 255-261
-
-
Cheng, L.1
You, Q.2
Yin, H.3
Holt, M.P.4
Ju, C.5
-
22
-
-
0024523935
-
Drug-protein conjugates-XVIII. Detection of antibodies towards the antimalarial amodiaquine and its quinone imine metabolite in man and the rat
-
Christie G., Breckenridge A.M., Park B.K. Drug-protein conjugates-XVIII. Detection of antibodies towards the antimalarial amodiaquine and its quinone imine metabolite in man and the rat. Biochemical Pharmacology 1989, 38:1451-1458.
-
(1989)
Biochemical Pharmacology
, vol.38
, pp. 1451-1458
-
-
Christie, G.1
Breckenridge, A.M.2
Park, B.K.3
-
23
-
-
77949494894
-
Nevirapine-associated early hepatotoxicity: incidence, risk factors, and associated mortality in a primary care ART programme in South Africa
-
Chu K.M., Boulle A.M., Ford N., Goemaere E., Asselman V., Van Cutsem G. Nevirapine-associated early hepatotoxicity: incidence, risk factors, and associated mortality in a primary care ART programme in South Africa. PLoS One 2010, 5:e9183.
-
(2010)
PLoS One
, vol.5
-
-
Chu, K.M.1
Boulle, A.M.2
Ford, N.3
Goemaere, E.4
Asselman, V.5
Van Cutsem, G.6
-
24
-
-
0025071113
-
Immunogenicity of amodiaquine in the rat
-
Clarke J.B., Maggs J.L., Kitteringham N.R., Park B.K. Immunogenicity of amodiaquine in the rat. International Archives of Allergy & Applied Immunology 1990, 91:335-342.
-
(1990)
International Archives of Allergy & Applied Immunology
, vol.91
, pp. 335-342
-
-
Clarke, J.B.1
Maggs, J.L.2
Kitteringham, N.R.3
Park, B.K.4
-
25
-
-
0025949403
-
Detection of antidrug IgG antibodies in patients with adverse drug reactions to amodiaquine
-
Clarke J.B., Neftel K., Kitteringham N.R., Park B.K. Detection of antidrug IgG antibodies in patients with adverse drug reactions to amodiaquine. International Archives of Allergy & Applied Immunology 1991, 95:369-375.
-
(1991)
International Archives of Allergy & Applied Immunology
, vol.95
, pp. 369-375
-
-
Clarke, J.B.1
Neftel, K.2
Kitteringham, N.R.3
Park, B.K.4
-
26
-
-
33645634796
-
Brief communication: severe hepatotoxicity of telithromycin: three case reports and literature review
-
Clay K.D., Hanson J.S., Pope S.D., Rissmiller R.W., Purdum P.P., Banks P.M. Brief communication: severe hepatotoxicity of telithromycin: three case reports and literature review. Annals of Internal Medicine 2006, 144:415-420.
-
(2006)
Annals of Internal Medicine
, vol.144
, pp. 415-420
-
-
Clay, K.D.1
Hanson, J.S.2
Pope, S.D.3
Rissmiller, R.W.4
Purdum, P.P.5
Banks, P.M.6
-
27
-
-
0028131568
-
First generation aromatase inhibitors-aminoglutethimide and testololactone
-
Cocconi G. First generation aromatase inhibitors-aminoglutethimide and testololactone. Breast Cancer Research and Treatment 1994, 30:57-80.
-
(1994)
Breast Cancer Research and Treatment
, vol.30
, pp. 57-80
-
-
Cocconi, G.1
-
28
-
-
0344395254
-
Aminoglutethimide-induced leucopenia in a mouse model: effects of metabolic and structural determinates
-
Coleman M.D., Khalaf L.F., Nicholls P.J. Aminoglutethimide-induced leucopenia in a mouse model: effects of metabolic and structural determinates. Environmental Toxicology and Pharmacology 2003, 15:27-32.
-
(2003)
Environmental Toxicology and Pharmacology
, vol.15
, pp. 27-32
-
-
Coleman, M.D.1
Khalaf, L.F.2
Nicholls, P.J.3
-
29
-
-
80052037842
-
Dendritic cell depletion exacerbates acetaminophen hepatotoxicity
-
Connolly M.K., Ayo D., Malhotra A., Hackman M., Bedrosian A.S., Ibrahim J., et al. Dendritic cell depletion exacerbates acetaminophen hepatotoxicity. Hepatology 2011, 10.1002/hep.24429.
-
(2011)
Hepatology
-
-
Connolly, M.K.1
Ayo, D.2
Malhotra, A.3
Hackman, M.4
Bedrosian, A.S.5
Ibrahim, J.6
-
30
-
-
0023936754
-
Hydralazine and procainamide inhibit T cell DNA methylation and induce autroreactivity
-
Cornacchia E., Golbus J., Maybaum J., Strahler J., Hanash S., Richardson B. Hydralazine and procainamide inhibit T cell DNA methylation and induce autroreactivity. Journal of Immunology 1988, 140:2197-2200.
-
(1988)
Journal of Immunology
, vol.140
, pp. 2197-2200
-
-
Cornacchia, E.1
Golbus, J.2
Maybaum, J.3
Strahler, J.4
Hanash, S.5
Richardson, B.6
-
31
-
-
0029988450
-
Adverse reactions to sulphonamide and sulphonamide-trimethoprim antimicrobials: clinical syndromes and pathogenesis
-
Cribb A.E., Lee B.L., Trepanier L.A., Spielberg S.P. Adverse reactions to sulphonamide and sulphonamide-trimethoprim antimicrobials: clinical syndromes and pathogenesis. Adverse Drug Reactions and Toxicological Reviews 1996, 15:9-50.
-
(1996)
Adverse Drug Reactions and Toxicological Reviews
, vol.15
, pp. 9-50
-
-
Cribb, A.E.1
Lee, B.L.2
Trepanier, L.A.3
Spielberg, S.P.4
-
32
-
-
0021345926
-
N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen
-
Dahlin D.C., Miwa G.T., Lu A.Y., Nelson S.D. N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen. The Proceedings of the National Academy of Sciences USA 1984, 81:1327-1331.
-
(1984)
The Proceedings of the National Academy of Sciences USA
, vol.81
, pp. 1327-1331
-
-
Dahlin, D.C.1
Miwa, G.T.2
Lu, A.Y.3
Nelson, S.D.4
-
33
-
-
0035045720
-
Homozygosity for alanine in the mitochondrial targeting sequence of superoxide dismutase and risk for severe alcoholic liver disease
-
Degoul F., Sutton A., Mansouri A., Cepanec C., Degott C., Fromenty B., et al. Homozygosity for alanine in the mitochondrial targeting sequence of superoxide dismutase and risk for severe alcoholic liver disease. Gastroenterology 2001, 120:1468-1474.
-
(2001)
Gastroenterology
, vol.120
, pp. 1468-1474
-
-
Degoul, F.1
Sutton, A.2
Mansouri, A.3
Cepanec, C.4
Degott, C.5
Fromenty, B.6
-
34
-
-
0037333972
-
Hydralazine may induce autoimmunity by inhibiting extracellular signal-regulated kinase pathway signaling
-
Deng C., Lu Q., Zhang Z., Rao T., Attwood J., Yung R., et al. Hydralazine may induce autoimmunity by inhibiting extracellular signal-regulated kinase pathway signaling. Arthritis & Rheumatism 2003, 48:746-756.
-
(2003)
Arthritis & Rheumatism
, vol.48
, pp. 746-756
-
-
Deng, C.1
Lu, Q.2
Zhang, Z.3
Rao, T.4
Attwood, J.5
Yung, R.6
-
35
-
-
70349694415
-
Inflammatory stress and idiosyncratic hepatotoxicity: hints from animal models
-
Deng X., Luyendyk J.P., Ganey P.E., Roth R.A. Inflammatory stress and idiosyncratic hepatotoxicity: hints from animal models. Pharmacological Reviews 2009, 61:262-282.
-
(2009)
Pharmacological Reviews
, vol.61
, pp. 262-282
-
-
Deng, X.1
Luyendyk, J.P.2
Ganey, P.E.3
Roth, R.A.4
-
36
-
-
33751183319
-
Modest inflammation enhances diclofenac hepatotoxicity in rats: role of neutrophils and bacterial translocation
-
Deng X., Stachlewitz R.F., Liguori M.J., Blomme E.A.G., Waring J.F., Luyendyk J.P., et al. Modest inflammation enhances diclofenac hepatotoxicity in rats: role of neutrophils and bacterial translocation. Journal of Pharmacology and Experimental Therapeutics 2006, 319:1191-1199.
-
(2006)
Journal of Pharmacology and Experimental Therapeutics
, vol.319
, pp. 1191-1199
-
-
Deng, X.1
Stachlewitz, R.F.2
Liguori, M.J.3
Blomme, E.A.G.4
Waring, J.F.5
Luyendyk, J.P.6
-
37
-
-
5644276291
-
Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases
-
Diao H., Kon S., Iwabuchi K., Kimura C., Morimoto J., Ito D., et al. Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases. Immunity 2004, 21:539-550.
-
(2004)
Immunity
, vol.21
, pp. 539-550
-
-
Diao, H.1
Kon, S.2
Iwabuchi, K.3
Kimura, C.4
Morimoto, J.5
Ito, D.6
-
38
-
-
0033927921
-
A mechanistic approach to understanding species differences in felbamate bioactivation: relevance to drug-induced idiosyncratic reactions
-
Dieckhaus C.M., Miller T.A., Sofia R.D., Macdonald T.L. A mechanistic approach to understanding species differences in felbamate bioactivation: relevance to drug-induced idiosyncratic reactions. Drug Metabolism and Disposition 2000, 28:814-822.
-
(2000)
Drug Metabolism and Disposition
, vol.28
, pp. 814-822
-
-
Dieckhaus, C.M.1
Miller, T.A.2
Sofia, R.D.3
Macdonald, T.L.4
-
39
-
-
0035019780
-
Role of gluathione-S-transferases A1-1, M1-1, P1-1 in the detoxificaiton of 2-phenylpropenal, a reactive felbamate metabolite
-
Dieckhaus C.M., Roller S.G., Santos W.L., Sofia R.D., Macdonald T.L. Role of gluathione-S-transferases A1-1, M1-1, P1-1 in the detoxificaiton of 2-phenylpropenal, a reactive felbamate metabolite. Chemical Research in Toxicology 2001, 2001:511-516.
-
(2001)
Chemical Research in Toxicology
, vol.2001
, pp. 511-516
-
-
Dieckhaus, C.M.1
Roller, S.G.2
Santos, W.L.3
Sofia, R.D.4
Macdonald, T.L.5
-
40
-
-
1542327563
-
Drug-induced liver injury associated with the use of nonnucleoside reverse-transcriptase inhibitors
-
Dieterich D.T., Robinson P.A., Love J., Stern J.O. Drug-induced liver injury associated with the use of nonnucleoside reverse-transcriptase inhibitors. Clinical Infectious Diseases 2004, 38(Suppl. 2):80-89.
-
(2004)
Clinical Infectious Diseases
, vol.38
, Issue.SUPPL. 2
, pp. 80-89
-
-
Dieterich, D.T.1
Robinson, P.A.2
Love, J.3
Stern, J.O.4
-
41
-
-
0021355816
-
Effects of prolonged administration of d-penicillamine or captopril in various strains of rats. Brown Norway rats treated with d-penicillamine develop autoantibodies, circulating immune complexes, and disseminated intravascular coagulation
-
Donker A.J., Venuto R.C., Vladutiu A.O., Brentjens J.R., Andres G.A. Effects of prolonged administration of d-penicillamine or captopril in various strains of rats. Brown Norway rats treated with d-penicillamine develop autoantibodies, circulating immune complexes, and disseminated intravascular coagulation. Clinical Immunology and Immunopathology 1984, 30:142-155.
-
(1984)
Clinical Immunology and Immunopathology
, vol.30
, pp. 142-155
-
-
Donker, A.J.1
Venuto, R.C.2
Vladutiu, A.O.3
Brentjens, J.R.4
Andres, G.A.5
-
42
-
-
0019945390
-
Metabolism of aminoglutethimide in the rat
-
Egger H., Bartlett F., Itterly W., Rodebaugh R., Shimanskas C. Metabolism of aminoglutethimide in the rat. Drug Metabolism and Disposition 1982, 10:405-412.
-
(1982)
Drug Metabolism and Disposition
, vol.10
, pp. 405-412
-
-
Egger, H.1
Bartlett, F.2
Itterly, W.3
Rodebaugh, R.4
Shimanskas, C.5
-
44
-
-
79952117348
-
Drug antigenicity, immunogenicity, and costimulatory signaling: evidence for formation of a functional antigen through immune cell metabolism
-
Elsheikh A., Lavergne S.N., Castrejon J.L., Farrell J., Wang H., Sathish J., et al. Drug antigenicity, immunogenicity, and costimulatory signaling: evidence for formation of a functional antigen through immune cell metabolism. Journal of Immunology 2010, 185:6448-6460.
-
(2010)
Journal of Immunology
, vol.185
, pp. 6448-6460
-
-
Elsheikh, A.1
Lavergne, S.N.2
Castrejon, J.L.3
Farrell, J.4
Wang, H.5
Sathish, J.6
-
45
-
-
2342430991
-
Molecular mechanisms of endotoxin tolerance
-
Fan H., Cook J.A. Molecular mechanisms of endotoxin tolerance. Journal of Endotoxin Research 2004, 10:71-84.
-
(2004)
Journal of Endotoxin Research
, vol.10
, pp. 71-84
-
-
Fan, H.1
Cook, J.A.2
-
47
-
-
0022502932
-
Agranulocytosis induced by propylthiouracil: evidence of a drug dependent antibody reacting with granulocytes, monocytes and haematopoietic progenitor cells
-
Fibbe W.E., Claas F.H.J., Van der Star-Dijlstra W., Schaafsma M.R., Meyboom R.H.B., Falkenburg J.H.F. Agranulocytosis induced by propylthiouracil: evidence of a drug dependent antibody reacting with granulocytes, monocytes and haematopoietic progenitor cells. British Journal of Haematology 1986, 64:363-373.
-
(1986)
British Journal of Haematology
, vol.64
, pp. 363-373
-
-
Fibbe, W.E.1
Claas, F.H.J.2
Van der Star-Dijlstra, W.3
Schaafsma, M.R.4
Meyboom, R.H.B.5
Falkenburg, J.H.F.6
-
48
-
-
0024318691
-
Fatal aplastic anaemia and liver toxicity caused by d-penicillamine treatment of rheumatoid arthritis
-
Fishel B., Tishler M., Caspi D., Yaron M. Fatal aplastic anaemia and liver toxicity caused by d-penicillamine treatment of rheumatoid arthritis. Annals of Rheumatic Diseases 1989, 48:609-610.
-
(1989)
Annals of Rheumatic Diseases
, vol.48
, pp. 609-610
-
-
Fishel, B.1
Tishler, M.2
Caspi, D.3
Yaron, M.4
-
49
-
-
0042469144
-
Th2-type immunopathological manifestations induced by mercury chloride or gold salts in the rat: signal transduction pathways, cellular mechanisms and genetic control
-
Fournie G.J., Saoudi A., Druet P., Pelletier L. Th2-type immunopathological manifestations induced by mercury chloride or gold salts in the rat: signal transduction pathways, cellular mechanisms and genetic control. Autoimmunity Reviews 2002, 1:205-212.
-
(2002)
Autoimmunity Reviews
, vol.1
, pp. 205-212
-
-
Fournie, G.J.1
Saoudi, A.2
Druet, P.3
Pelletier, L.4
-
50
-
-
67049169349
-
Sensitivity of liver injury in heterozygous Sod2 knockout mice treated with troglitazone or acetaminophen
-
Fujimoto K., Kumagai K., Ito K., Arakawa S., Ando Y., Oda S.I, et al. Sensitivity of liver injury in heterozygous Sod2 knockout mice treated with troglitazone or acetaminophen. Toxicologic Pathology 2009, 37:193-200.
-
(2009)
Toxicologic Pathology
, vol.37
, pp. 193-200
-
-
Fujimoto, K.1
Kumagai, K.2
Ito, K.3
Arakawa, S.4
Ando, Y.5
Oda, S.I.6
-
51
-
-
0030972414
-
Demonstration of a cellular immune response in halothane-exposed guinea pigs
-
Furst S.M., Luedke D., Gaw H.H., Reich R., Gandolfi A.J. Demonstration of a cellular immune response in halothane-exposed guinea pigs. Toxicology and Applied Pharmacology 1997, 143:245-255.
-
(1997)
Toxicology and Applied Pharmacology
, vol.143
, pp. 245-255
-
-
Furst, S.M.1
Luedke, D.2
Gaw, H.H.3
Reich, R.4
Gandolfi, A.J.5
-
52
-
-
0031814439
-
A comparison of the covalent binding of clozapine and olanzapine to human neutrophils in vitro and in vivo
-
Gardner I., Leeder J.S., Chin T., Zahid N., Uetrecht J.P. A comparison of the covalent binding of clozapine and olanzapine to human neutrophils in vitro and in vivo. Molecular Pharmacology 1998, 53:999-1008.
-
(1998)
Molecular Pharmacology
, vol.53
, pp. 999-1008
-
-
Gardner, I.1
Leeder, J.S.2
Chin, T.3
Zahid, N.4
Uetrecht, J.P.5
-
53
-
-
33845945094
-
HLA-Cw8 primarily associated with hypersensitivity to nevirapine
-
Gatanaga H., Yazaki H., Tanuma J., Honda M., Genka I., Teruya K., et al. HLA-Cw8 primarily associated with hypersensitivity to nevirapine. AIDS 2007, 21:264-265.
-
(2007)
AIDS
, vol.21
, pp. 264-265
-
-
Gatanaga, H.1
Yazaki, H.2
Tanuma, J.3
Honda, M.4
Genka, I.5
Teruya, K.6
-
54
-
-
33845499048
-
Systematic review and meta-analysis: d-Penicillamine vs. placebo/no intervention in patients with primary biliary cirrhosis-Cochrane Hepato-Biliary Group
-
Gong Y., Klingenberg S.L., Gluud C. Systematic review and meta-analysis: d-Penicillamine vs. placebo/no intervention in patients with primary biliary cirrhosis-Cochrane Hepato-Biliary Group. Alimentary Pharmacology & Therapeutics 2006, 24:1535-1544.
-
(2006)
Alimentary Pharmacology & Therapeutics
, vol.24
, pp. 1535-1544
-
-
Gong, Y.1
Klingenberg, S.L.2
Gluud, C.3
-
55
-
-
0021911962
-
Metabolism of aminoglutethimide in humans: quantification and clinical relevance of induced metabolism
-
Goss P.E., Jarman M., Griggs L.J. Metabolism of aminoglutethimide in humans: quantification and clinical relevance of induced metabolism. British Journal of Cancer 1985, 51:259-262.
-
(1985)
British Journal of Cancer
, vol.51
, pp. 259-262
-
-
Goss, P.E.1
Jarman, M.2
Griggs, L.J.3
-
56
-
-
0024679059
-
Ranitidine. An updated review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in peptic ulcer disease and other allied diseases
-
Grant S.M., Langtry H.D., Brogden R.N. Ranitidine. An updated review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in peptic ulcer disease and other allied diseases. Drugs 1989, 37:801-870.
-
(1989)
Drugs
, vol.37
, pp. 801-870
-
-
Grant, S.M.1
Langtry, H.D.2
Brogden, R.N.3
-
57
-
-
0031770078
-
Examination of possible toxic and immune mechanisms of clozapine-induced agranulocytosis
-
Guest I., Sokoluk B., MacCrimmon J., Uetrecht J. Examination of possible toxic and immune mechanisms of clozapine-induced agranulocytosis. Toxicology 1998, 131:53-65.
-
(1998)
Toxicology
, vol.131
, pp. 53-65
-
-
Guest, I.1
Sokoluk, B.2
MacCrimmon, J.3
Uetrecht, J.4
-
58
-
-
0023031741
-
Agranulocytosis associated with aminoglutethimide: pharmacological and marrow studies
-
Harris A.L., Hughes G., Barrett A.J., Abusrewil S., Dowsett M., Smith I.E. Agranulocytosis associated with aminoglutethimide: pharmacological and marrow studies. British Journal of Cancer 1986, 54:119-122.
-
(1986)
British Journal of Cancer
, vol.54
, pp. 119-122
-
-
Harris, A.L.1
Hughes, G.2
Barrett, A.J.3
Abusrewil, S.4
Dowsett, M.5
Smith, I.E.6
-
59
-
-
0026546128
-
The mechanism of bioactivation and antigen formation of amodiaquine in the rat
-
Harrison A.C., Kitteringham N.R., Clarke J.B., Park B.K. The mechanism of bioactivation and antigen formation of amodiaquine in the rat. Biochemical Pharmacology 1992, 43:1421-1430.
-
(1992)
Biochemical Pharmacology
, vol.43
, pp. 1421-1430
-
-
Harrison, A.C.1
Kitteringham, N.R.2
Clarke, J.B.3
Park, B.K.4
-
60
-
-
0028922204
-
Trifluoroacetylation potentiates the humoral immune response to halothane in the guinea pig
-
Hastings K.L., Thomas C., Brown A.P., Gandolfi A.J. Trifluoroacetylation potentiates the humoral immune response to halothane in the guinea pig. Immunopharmacology and Immunotoxicology 1995, 17:201-213.
-
(1995)
Immunopharmacology and Immunotoxicology
, vol.17
, pp. 201-213
-
-
Hastings, K.L.1
Thomas, C.2
Brown, A.P.3
Gandolfi, A.J.4
-
61
-
-
67349236051
-
The genetics and epigenetics of autoimmune diseases
-
Hewagama A., Richardson B. The genetics and epigenetics of autoimmune diseases. Journal of Autoimmunity 2009, 33:3-11.
-
(2009)
Journal of Autoimmunity
, vol.33
, pp. 3-11
-
-
Hewagama, A.1
Richardson, B.2
-
62
-
-
0001580881
-
Neutropenia following amidopyrine
-
Hoffman A.M., Butt E.M., Hickey N.G. Neutropenia following amidopyrine. JAMA 1934, 102:1213-1214.
-
(1934)
JAMA
, vol.102
, pp. 1213-1214
-
-
Hoffman, A.M.1
Butt, E.M.2
Hickey, N.G.3
-
63
-
-
0030934336
-
Fialuridine is phosphorylated and inhibits DNA synthesis in isolated rat hepatic mitochondria
-
Horn D.M., Neeb L.A., Colacino J.M., Richardson F.C. Fialuridine is phosphorylated and inhibits DNA synthesis in isolated rat hepatic mitochondria. Antiviral Research 1997, 34:71-74.
-
(1997)
Antiviral Research
, vol.34
, pp. 71-74
-
-
Horn, D.M.1
Neeb, L.A.2
Colacino, J.M.3
Richardson, F.C.4
-
64
-
-
0022518274
-
D-penicillamine: chemistry and clinical use in rheumatic disease
-
Howard-Lock H.E., Lock C.J., Mewa A., Kean W.F. d-penicillamine: chemistry and clinical use in rheumatic disease. Seminars in Arthritis and Rheumatism 1986, 15:261-281.
-
(1986)
Seminars in Arthritis and Rheumatism
, vol.15
, pp. 261-281
-
-
Howard-Lock, H.E.1
Lock, C.J.2
Mewa, A.3
Kean, W.F.4
-
65
-
-
0014812460
-
Aminoglutethimide: a 'side-effect' turned therapeutic advantage
-
Hughes S.W.M., Burley D.M. Aminoglutethimide: a 'side-effect' turned therapeutic advantage. Postgraduate Medical Journal 1970, 46:409-416.
-
(1970)
Postgraduate Medical Journal
, vol.46
, pp. 409-416
-
-
Hughes, S.W.M.1
Burley, D.M.2
-
66
-
-
0026766121
-
Dose-response studies in murine mercury-induced autoimmunity and immune-complex disease
-
Hultman P., Enestrom S. Dose-response studies in murine mercury-induced autoimmunity and immune-complex disease. Toxicology and Applied Pharmacology 1992, 113:199-208.
-
(1992)
Toxicology and Applied Pharmacology
, vol.113
, pp. 199-208
-
-
Hultman, P.1
Enestrom, S.2
-
68
-
-
0036158897
-
Felbamate-induced apoptosis of hematopoietic cells is mediated by redox-sensitive and redox-independent pathways
-
Husain Z., Pinto C., Sofia R.D., Yunis E.J. Felbamate-induced apoptosis of hematopoietic cells is mediated by redox-sensitive and redox-independent pathways. Epilepsy Research 2002, 48:57-69.
-
(2002)
Epilepsy Research
, vol.48
, pp. 57-69
-
-
Husain, Z.1
Pinto, C.2
Sofia, R.D.3
Yunis, E.J.4
-
69
-
-
30744436753
-
Serum transaminases in children with Wilsons disease
-
Iorio R., D'Ambrosi M., Marcellini M., Barbera C., Maggiore G., Zancan L., et al. Serum transaminases in children with Wilsons disease. Journal of Pediatric Gastroenterology and Nutrition 2004, 39:331-336.
-
(2004)
Journal of Pediatric Gastroenterology and Nutrition
, vol.39
, pp. 331-336
-
-
Iorio, R.1
D'Ambrosi, M.2
Marcellini, M.3
Barbera, C.4
Maggiore, G.5
Zancan, L.6
-
70
-
-
31544478506
-
In vitro and animal models of drug-induced blood dyscrasias
-
Ip J., Uetrecht J. In vitro and animal models of drug-induced blood dyscrasias. Environmental Toxicology and Pharmacology 2006, 21:135-140.
-
(2006)
Environmental Toxicology and Pharmacology
, vol.21
, pp. 135-140
-
-
Ip, J.1
Uetrecht, J.2
-
71
-
-
43149098302
-
Testing the hypothesis that selenium deficiency is a risk factor for clozapine-induced agranulocytosis in rats
-
Ip J., Uetrecht J.P. Testing the hypothesis that selenium deficiency is a risk factor for clozapine-induced agranulocytosis in rats. Chemical Research in Toxicology 2008, 21:874-878.
-
(2008)
Chemical Research in Toxicology
, vol.21
, pp. 874-878
-
-
Ip, J.1
Uetrecht, J.P.2
-
72
-
-
43349083517
-
Testing the hypothesis that vitamin C deficiency is a risk factor for clozapine-induced agranulocytosis using guinea pigs and ODS rats
-
Ip J., Wilson J.X., Uetrecht J.P. Testing the hypothesis that vitamin C deficiency is a risk factor for clozapine-induced agranulocytosis using guinea pigs and ODS rats. Chemical Research in Toxicology 2008, 21:869-873.
-
(2008)
Chemical Research in Toxicology
, vol.21
, pp. 869-873
-
-
Ip, J.1
Wilson, J.X.2
Uetrecht, J.P.3
-
74
-
-
77955409429
-
Effect of clozapine on neutrophil kinetics in rabbits
-
Iverson S., Kautiainen A., Ip J., Uetrecht J.P. Effect of clozapine on neutrophil kinetics in rabbits. Chemical Research in Toxicology 2010, 23:1184-1191.
-
(2010)
Chemical Research in Toxicology
, vol.23
, pp. 1184-1191
-
-
Iverson, S.1
Kautiainen, A.2
Ip, J.3
Uetrecht, J.P.4
-
75
-
-
34347236533
-
Troglitazone hepatotoxicity: are we getting closer to understanding idiosyncratic liver injury?
-
Jaeschke H. Troglitazone hepatotoxicity: are we getting closer to understanding idiosyncratic liver injury?. Toxicological Sciences 2007, 97:1-3.
-
(2007)
Toxicological Sciences
, vol.97
, pp. 1-3
-
-
Jaeschke, H.1
-
76
-
-
83255192265
-
Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity
-
Jaeschke H., Williams C.D., Ramachandran A., Bajt M.L. Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity. Liver International 2011, 10.1111/j.1478-3231.2011.02501.x.
-
(2011)
Liver International
-
-
Jaeschke, H.1
Williams, C.D.2
Ramachandran, A.3
Bajt, M.L.4
-
77
-
-
0015754446
-
Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo
-
Jollow D.J., Mitchell J.R., Potter W.Z., Davis D.C., Gillette J.R., Brodie B.B. Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo. Journal of Pharmacology and Experimental Therapeutics 1973, 187:195-202.
-
(1973)
Journal of Pharmacology and Experimental Therapeutics
, vol.187
, pp. 195-202
-
-
Jollow, D.J.1
Mitchell, J.R.2
Potter, W.Z.3
Davis, D.C.4
Gillette, J.R.5
Brodie, B.B.6
-
78
-
-
0036913249
-
Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice
-
Ju C., Reilly T.P., Bourdi M., Radonovich M.F., Brady J.N., George J.W., et al. Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice. Chemical Research in Toxicology 2002, 15:1504-1513.
-
(2002)
Chemical Research in Toxicology
, vol.15
, pp. 1504-1513
-
-
Ju, C.1
Reilly, T.P.2
Bourdi, M.3
Radonovich, M.F.4
Brady, J.N.5
George, J.W.6
-
79
-
-
67349231918
-
Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity
-
Kashimshetty R., Desai V.G., Kale V.M., Lee T., Moland C.L., Branham W.S., et al. Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity. Toxicology and Applied Pharmacology 2009, 238:150-159.
-
(2009)
Toxicology and Applied Pharmacology
, vol.238
, pp. 150-159
-
-
Kashimshetty, R.1
Desai, V.G.2
Kale, V.M.3
Lee, T.4
Moland, C.L.5
Branham, W.S.6
-
80
-
-
33749989821
-
Mitochondrial involvement in drug-induced hepatic injury
-
Kass G.E. Mitochondrial involvement in drug-induced hepatic injury. Chemico-Biological Interactions 2006, 163:145-159.
-
(2006)
Chemico-Biological Interactions
, vol.163
, pp. 145-159
-
-
Kass, G.E.1
-
81
-
-
0031440072
-
Evaluation of case reports of aplastic anemia among patients treated with felbamate
-
Kaufman D.W., Kelly J.P., Anderson K.T., Harmon D.C., Shapiro S. Evaluation of case reports of aplastic anemia among patients treated with felbamate. Epilepsia 1997, 38:1265-1269.
-
(1997)
Epilepsia
, vol.38
, pp. 1265-1269
-
-
Kaufman, D.W.1
Kelly, J.P.2
Anderson, K.T.3
Harmon, D.C.4
Shapiro, S.5
-
82
-
-
84872206365
-
-
Paper presented at the the 4th International AIDS Society Meeting, Sydney, Australia
-
Keane N.M., Nolan D., Phillips E.J., Lucas A.D., Almeida C.A., Martin A.M., et al. Use of the ELISpot assay to detect abacavir- and nevirapine-induced IFN- responses in PBMC from HIV-infected patients with abacavir or nevirpine hypersensitivity reactions 2007, Paper presented at the the 4th International AIDS Society Meeting, Sydney, Australia.
-
(2007)
Use of the ELISpot assay to detect abacavir- and nevirapine-induced IFN- responses in PBMC from HIV-infected patients with abacavir or nevirpine hypersensitivity reactions
-
-
Keane, N.M.1
Nolan, D.2
Phillips, E.J.3
Lucas, A.D.4
Almeida, C.A.5
Martin, A.M.6
-
83
-
-
45549106783
-
Adverse drug reactions with halogenated anesthetics
-
Kharasch E.D. Adverse drug reactions with halogenated anesthetics. Clinical Pharmacology & Therapeutics 2008, 84:158-162.
-
(2008)
Clinical Pharmacology & Therapeutics
, vol.84
, pp. 158-162
-
-
Kharasch, E.D.1
-
84
-
-
70349298831
-
Halothane-induced liver injury is mediated by interleukin-17 in mice
-
Kobayashi E., Kobayashi M., Tsuneyama K., Fukami T., Nakajima M., Yokoi T. Halothane-induced liver injury is mediated by interleukin-17 in mice. Toxicological Sciences 2009, 111:302-310.
-
(2009)
Toxicological Sciences
, vol.111
, pp. 302-310
-
-
Kobayashi, E.1
Kobayashi, M.2
Tsuneyama, K.3
Fukami, T.4
Nakajima, M.5
Yokoi, T.6
-
85
-
-
0035956929
-
Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis
-
Kokoszka J.E., Coskun P., Espositio L.A., Wallace D.C. Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis. Proceedings of the Academy of Natural Sciences 2001, 98:2278-2283.
-
(2001)
Proceedings of the Academy of Natural Sciences
, vol.98
, pp. 2278-2283
-
-
Kokoszka, J.E.1
Coskun, P.2
Espositio, L.A.3
Wallace, D.C.4
-
86
-
-
0030953630
-
Autoimmunity caused by disruption of central T cell tolerance: a murine model of drug-induced lupus
-
Kretz-Rommel A., Duncan S.R., Rubin R.L. Autoimmunity caused by disruption of central T cell tolerance: a murine model of drug-induced lupus. Journal of Clinical Investigations 1997, 99:1888-1896.
-
(1997)
Journal of Clinical Investigations
, vol.99
, pp. 1888-1896
-
-
Kretz-Rommel, A.1
Duncan, S.R.2
Rubin, R.L.3
-
87
-
-
0022397479
-
D-Penicillamine-induced acute hypersensitivity pneumonitis and cholestatic hepatitis in a patient with rheumatoid arthritis
-
Kumar A., Bhat A., Gupta D.K., Goel A., Malaviya A.N. d-Penicillamine-induced acute hypersensitivity pneumonitis and cholestatic hepatitis in a patient with rheumatoid arthritis. Clinical and Experimental Rheumatology 1985, 3:337-339.
-
(1985)
Clinical and Experimental Rheumatology
, vol.3
, pp. 337-339
-
-
Kumar, A.1
Bhat, A.2
Gupta, D.K.3
Goel, A.4
Malaviya, A.N.5
-
88
-
-
78649447854
-
Regulatory T cells: the suppressor arm of the immune system
-
Langier S., Sade K., Kivity S. Regulatory T cells: the suppressor arm of the immune system. Autoimmunity Reviews 2010, 10:112-115.
-
(2010)
Autoimmunity Reviews
, vol.10
, pp. 112-115
-
-
Langier, S.1
Sade, K.2
Kivity, S.3
-
89
-
-
33745671839
-
Association of drug-serum protein adducts and anti-drug antibodies in dogs with sulphonamide hypersensitivity: a naturally occurring model of idiosyncratic drug toxicity
-
Lavergne S.N., Danhof R.S., Volkman E.M., Trepanier L.A. Association of drug-serum protein adducts and anti-drug antibodies in dogs with sulphonamide hypersensitivity: a naturally occurring model of idiosyncratic drug toxicity. Clinical & Experimental Allergy 2006, 36:907-915.
-
(2006)
Clinical & Experimental Allergy
, vol.36
, pp. 907-915
-
-
Lavergne, S.N.1
Danhof, R.S.2
Volkman, E.M.3
Trepanier, L.A.4
-
90
-
-
36849022039
-
Anti-myeloperoxidase and anti-cathepsin G antibodies in sulphonamide hypersensitivity
-
Lavergne S.N., Drescher N.J., Trepanier L.A. Anti-myeloperoxidase and anti-cathepsin G antibodies in sulphonamide hypersensitivity. Clinical & Experimental Allergy 2007, 38:199-207.
-
(2007)
Clinical & Experimental Allergy
, vol.38
, pp. 199-207
-
-
Lavergne, S.N.1
Drescher, N.J.2
Trepanier, L.A.3
-
91
-
-
12444273307
-
Evaluation of the clinical, immunologic, and biochemical effects of nitroso sulfamethoxazole administration to dogs: a pilot study
-
Lavergne S.N., Volkman E.M., Maki J.E., Yoder A.R., Trepanier L.A. Evaluation of the clinical, immunologic, and biochemical effects of nitroso sulfamethoxazole administration to dogs: a pilot study. Toxicology 2005, 208:63-72.
-
(2005)
Toxicology
, vol.208
, pp. 63-72
-
-
Lavergne, S.N.1
Volkman, E.M.2
Maki, J.E.3
Yoder, A.R.4
Trepanier, L.A.5
-
92
-
-
0029838063
-
Neurodegeneration myocardial injury and perinatal death in mitochondrial superoxidase dismutase deficient mice
-
Lebovitz R.M., Zhang H., Vogel H., Cartwright J., Dionne L., Lu N., et al. Neurodegeneration myocardial injury and perinatal death in mitochondrial superoxidase dismutase deficient mice. Proceedings of the Academy of Natural Sciences 1996, 93:9782-9787.
-
(1996)
Proceedings of the Academy of Natural Sciences
, vol.93
, pp. 9782-9787
-
-
Lebovitz, R.M.1
Zhang, H.2
Vogel, H.3
Cartwright, J.4
Dionne, L.5
Lu, N.6
-
93
-
-
48449103315
-
Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2+/- mice: two-stage oxidative injury
-
Lee Y.H., Chung M.C.M., Lin Q., Boelsterli U.A. Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2+/- mice: two-stage oxidative injury. Toxicology and Applied Pharmacology 2008, 231:43-51.
-
(2008)
Toxicology and Applied Pharmacology
, vol.231
, pp. 43-51
-
-
Lee, Y.H.1
Chung, M.C.M.2
Lin, Q.3
Boelsterli, U.A.4
-
94
-
-
34248562343
-
Evaluation of felbamate and other antiepileptic drug toxicity potential based on hepatic protein covalent binding and gene expression
-
Leone A.M., Kao L.M., McMillian M.K., Nie A.Y., Parker J.B., Kelley M.F., et al. Evaluation of felbamate and other antiepileptic drug toxicity potential based on hepatic protein covalent binding and gene expression. Chemical Research in Toxicology 2007, 20:600-608.
-
(2007)
Chemical Research in Toxicology
, vol.20
, pp. 600-608
-
-
Leone, A.M.1
Kao, L.M.2
McMillian, M.K.3
Nie, A.Y.4
Parker, J.B.5
Kelley, M.F.6
-
95
-
-
84872204422
-
Changes in hepatic gene expression induced by amodiaquine in rats
-
Li J., Kourteva G., Hilton H., Cai P., Workman H., Haggerty H., et al. Changes in hepatic gene expression induced by amodiaquine in rats. The Toxicologist 2011, 120:323.
-
(2011)
The Toxicologist
, vol.120
, pp. 323
-
-
Li, J.1
Kourteva, G.2
Hilton, H.3
Cai, P.4
Workman, H.5
Haggerty, H.6
-
96
-
-
67651002560
-
Covalent binding of penicillamine to macrophages: implications for penicillamine-induced autoimmunity
-
Li J., Mannargudi B., Uetrecht J.P. Covalent binding of penicillamine to macrophages: implications for penicillamine-induced autoimmunity. Chemical Research in Toxicology 2009, 22:1277-1284.
-
(2009)
Chemical Research in Toxicology
, vol.22
, pp. 1277-1284
-
-
Li, J.1
Mannargudi, B.2
Uetrecht, J.P.3
-
97
-
-
77949320496
-
The danger hypothesis as applied to idiosyncratic drug reactions
-
Li J., Uetrecht J. The danger hypothesis as applied to idiosyncratic drug reactions. Handbook of Experimental Pharmacology 2010, 196:493-509.
-
(2010)
Handbook of Experimental Pharmacology
, vol.196
, pp. 493-509
-
-
Li, J.1
Uetrecht, J.2
-
98
-
-
70349310507
-
D-Penicillamine-induced autoimmunity: relationship to macrophage activation
-
Li J., Uetrecht J.P. d-Penicillamine-induced autoimmunity: relationship to macrophage activation. Chemical Research in Toxicology 2009, 22:1526-1533.
-
(2009)
Chemical Research in Toxicology
, vol.22
, pp. 1526-1533
-
-
Li, J.1
Uetrecht, J.P.2
-
99
-
-
84872205896
-
Immunological aspects of an animal model of amodiaquine-induced liver toxicity
-
Li J., Workman H., Cai P., Kourteva G., Hilton H., Haggerty H., et al. Immunological aspects of an animal model of amodiaquine-induced liver toxicity. The Toxicologist 2011, 120:323.
-
(2011)
The Toxicologist
, vol.120
, pp. 323
-
-
Li, J.1
Workman, H.2
Cai, P.3
Kourteva, G.4
Hilton, H.5
Haggerty, H.6
-
100
-
-
84863769037
-
Study of liver lymphocytes in amodiaquine-induced hepatotoxicity in Brown Norway rats
-
Liu F., Cai P., Li J., Uetrecht J. Study of liver lymphocytes in amodiaquine-induced hepatotoxicity in Brown Norway rats. The Toxicologist 2011, 120:93.
-
(2011)
The Toxicologist
, vol.120
, pp. 93
-
-
Liu, F.1
Cai, P.2
Li, J.3
Uetrecht, J.4
-
101
-
-
0029555342
-
Clozapine is oxidized by activated human neutrophils to a reactive nitrinium ion that irreversibly binds to the cells
-
Liu Z.C., Uetrecht J.P. Clozapine is oxidized by activated human neutrophils to a reactive nitrinium ion that irreversibly binds to the cells. Journal of Pharmacology and Experimental Therapeutics 1995, 275:1476-1483.
-
(1995)
Journal of Pharmacology and Experimental Therapeutics
, vol.275
, pp. 1476-1483
-
-
Liu, Z.C.1
Uetrecht, J.P.2
-
102
-
-
0025014525
-
Experimental autoimmune hepatitis: disease induction, time course and T-cell reactivity
-
Lohse A.W., Manns M., Dienes H.P., Meyer zum Buschenfelde K.H., Cohen I.R. Experimental autoimmune hepatitis: disease induction, time course and T-cell reactivity. Hepatology 1990, 11:24-30.
-
(1990)
Hepatology
, vol.11
, pp. 24-30
-
-
Lohse, A.W.1
Manns, M.2
Dienes, H.P.3
Meyer zum Buschenfelde, K.H.4
Cohen, I.R.5
-
103
-
-
0141563559
-
Ranitidine treatment during a modest inflammatory response precipitates idiosyncrasy-like liver injury in rats
-
Luyendyk J.P., Maddox J.F., Cosma G.N., Ganey P.E., Cockrell G.L., Roth R.A. Ranitidine treatment during a modest inflammatory response precipitates idiosyncrasy-like liver injury in rats. Journal of Pharmacology and Experimental Therapeutics 2003, 307:9-16.
-
(2003)
Journal of Pharmacology and Experimental Therapeutics
, vol.307
, pp. 9-16
-
-
Luyendyk, J.P.1
Maddox, J.F.2
Cosma, G.N.3
Ganey, P.E.4
Cockrell, G.L.5
Roth, R.A.6
-
104
-
-
37349023127
-
Case-control exploration of relationships between early rash or liver toxicity and plasma concentrations of nevirapine and primary metabolites
-
MacGregor T.R., Hall D.B. Case-control exploration of relationships between early rash or liver toxicity and plasma concentrations of nevirapine and primary metabolites. HIV Clinical Trials 2007, 8:391-399.
-
(2007)
HIV Clinical Trials
, vol.8
, pp. 391-399
-
-
MacGregor, T.R.1
Hall, D.B.2
-
106
-
-
12144287198
-
Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant
-
Martin A.M., Nolan D., Gaudieri S., Almeida C.A., Nolan R., James I., et al. Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Proceedings of the National Academy of Sciences 2004, 101:4180-4185.
-
(2004)
Proceedings of the National Academy of Sciences
, vol.101
, pp. 4180-4185
-
-
Martin, A.M.1
Nolan, D.2
Gaudieri, S.3
Almeida, C.A.4
Nolan, R.5
James, I.6
-
107
-
-
12144260460
-
Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T-cell counts
-
Martin A.M., Nolan D., James I., Cameron P., Keller J., Moore C., et al. Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T-cell counts. AIDS 2005, 19:97-99.
-
(2005)
AIDS
, vol.19
, pp. 97-99
-
-
Martin, A.M.1
Nolan, D.2
James, I.3
Cameron, P.4
Keller, J.5
Moore, C.6
-
108
-
-
1642457336
-
Tolerance induced by low dose d-penicillamine in the Brown Norway rat model of drug-induced autoimmunity is immune-mediated
-
Masson M.J., Uetrecht J.P. Tolerance induced by low dose d-penicillamine in the Brown Norway rat model of drug-induced autoimmunity is immune-mediated. Chemical Research in Toxicology 2004, 17:82-94.
-
(2004)
Chemical Research in Toxicology
, vol.17
, pp. 82-94
-
-
Masson, M.J.1
Uetrecht, J.P.2
-
109
-
-
0345146918
-
Role of interleukin-6 in hepatic heat shock protein expression and protection against acetaminophen-induced liver disease
-
Masubuchi Y., Bourdi M., Reilly T.P., Graf M.L., George J.W., Pohl L.R. Role of interleukin-6 in hepatic heat shock protein expression and protection against acetaminophen-induced liver disease. Biochemical and Biophysical Research Communications 2003, 304:207-212.
-
(2003)
Biochemical and Biophysical Research Communications
, vol.304
, pp. 207-212
-
-
Masubuchi, Y.1
Bourdi, M.2
Reilly, T.P.3
Graf, M.L.4
George, J.W.5
Pohl, L.R.6
-
110
-
-
33646112416
-
Mitochondrial permeability transition as a potential determinant of hepatotoxicity of antidiabetic thiazolidinediones
-
Masubuchi Y., Kano S., Horie T. Mitochondrial permeability transition as a potential determinant of hepatotoxicity of antidiabetic thiazolidinediones. Toxicology 2006, 222:233-239.
-
(2006)
Toxicology
, vol.222
, pp. 233-239
-
-
Masubuchi, Y.1
Kano, S.2
Horie, T.3
-
111
-
-
11144310166
-
Involvement of mitochondrial permeability transition in acetaminophen-induced liver injury in mice
-
Masubuchi Y., Suda C., Horie T. Involvement of mitochondrial permeability transition in acetaminophen-induced liver injury in mice. Journal of Hepatology 2005, 42:110-116.
-
(2005)
Journal of Hepatology
, vol.42
, pp. 110-116
-
-
Masubuchi, Y.1
Suda, C.2
Horie, T.3
-
112
-
-
0031739843
-
Acute, subchronic, and chronic toxicity studies with felbamate, 2-phenyl-1,3-propanediol dicarbamate
-
McGee J.H., Erikson D.J., Galbreath C., Willigan D.A., Sofia R.D. Acute, subchronic, and chronic toxicity studies with felbamate, 2-phenyl-1,3-propanediol dicarbamate. Toxicological Sciences 1998, 45:225-232.
-
(1998)
Toxicological Sciences
, vol.45
, pp. 225-232
-
-
McGee, J.H.1
Erikson, D.J.2
Galbreath, C.3
Willigan, D.A.4
Sofia, R.D.5
-
113
-
-
79956313436
-
A fresh look at the mechanism of isoniazid-induced hepatotoxicity
-
Metushi I.G., Cai P., Zhu X., Nakagawa T., Uetrecht J.P. A fresh look at the mechanism of isoniazid-induced hepatotoxicity. Clinical Pharmacology & Therapeutics 2011, 89:911-914.
-
(2011)
Clinical Pharmacology & Therapeutics
, vol.89
, pp. 911-914
-
-
Metushi, I.G.1
Cai, P.2
Zhu, X.3
Nakagawa, T.4
Uetrecht, J.P.5
-
114
-
-
0024803303
-
Immunological alterations inducible by mercury compounds. III. H-2A acts as an immune response and H-2E as an immune " suppression" locus for HgCl2-induced antinucleolar autoantibodies
-
Mirtcheva J., Pfeiffer C., De Bruijn J.A., Jacquesmart F., Gleichmann E. Immunological alterations inducible by mercury compounds. III. H-2A acts as an immune response and H-2E as an immune " suppression" locus for HgCl2-induced antinucleolar autoantibodies. Europen Journal of Immunology 1989, 19:2257-2261.
-
(1989)
Europen Journal of Immunology
, vol.19
, pp. 2257-2261
-
-
Mirtcheva, J.1
Pfeiffer, C.2
De Bruijn, J.A.3
Jacquesmart, F.4
Gleichmann, E.5
-
115
-
-
0015748302
-
Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism
-
Mitchell J.R., Jollow D.J., Potter W.Z., Davis D.C., Gillette J.R., Brodie B.B. Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism. Journal of Pharmacology and Experimental Therapeutics 1973, 187:185-194.
-
(1973)
Journal of Pharmacology and Experimental Therapeutics
, vol.187
, pp. 185-194
-
-
Mitchell, J.R.1
Jollow, D.J.2
Potter, W.Z.3
Davis, D.C.4
Gillette, J.R.5
Brodie, B.B.6
-
116
-
-
0017229380
-
Isoniazid liver injury: clinical spectrum, pathology, and probable pathogenesis
-
Mitchell J.R., Zimmerman H.J., Ishak K.G., Thorgeirsson U.P., Timbrell J.A., Snodgrass W.R., et al. Isoniazid liver injury: clinical spectrum, pathology, and probable pathogenesis. Annals of Internal Medicine 1976, 84:181-192.
-
(1976)
Annals of Internal Medicine
, vol.84
, pp. 181-192
-
-
Mitchell, J.R.1
Zimmerman, H.J.2
Ishak, K.G.3
Thorgeirsson, U.P.4
Timbrell, J.A.5
Snodgrass, W.R.6
-
117
-
-
0003069475
-
Agranulocytosis due to the occurrence of leukocyte-agglutinins
-
Moeschlin S., Wagner K. Agranulocytosis due to the occurrence of leukocyte-agglutinins. Acta Haematologica 1952, 8:29-41.
-
(1952)
Acta Haematologica
, vol.8
, pp. 29-41
-
-
Moeschlin, S.1
Wagner, K.2
-
118
-
-
0035119064
-
Regulation of cytochrome P450 by inflammatory mediators: why and how
-
Morgan E.T. Regulation of cytochrome P450 by inflammatory mediators: why and how. Drug Metabolism and Disposition 2001, 29:207-212.
-
(2001)
Drug Metabolism and Disposition
, vol.29
, pp. 207-212
-
-
Morgan, E.T.1
-
119
-
-
34447503805
-
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
-
Mucida D., Park Y., Kim G., Turovskaya O., Scott I., Kronenberg M., et al. Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 2007, 317:256-260.
-
(2007)
Science
, vol.317
, pp. 256-260
-
-
Mucida, D.1
Park, Y.2
Kim, G.3
Turovskaya, O.4
Scott, I.5
Kronenberg, M.6
-
120
-
-
0028950762
-
A comparative study of mouse liver proteins arylated by reactive metabolites of acetaminophen and its nonhepatotoxic regioisomer, 3'-hydroxyacetanilide
-
Myers T.G., Dietz E.C., Anderson N.L., Khairallah E.A., Cohen S.D., Nelson S.D. A comparative study of mouse liver proteins arylated by reactive metabolites of acetaminophen and its nonhepatotoxic regioisomer, 3'-hydroxyacetanilide. Chemical Research in Toxicology 1995, 8:403-413.
-
(1995)
Chemical Research in Toxicology
, vol.8
, pp. 403-413
-
-
Myers, T.G.1
Dietz, E.C.2
Anderson, N.L.3
Khairallah, E.A.4
Cohen, S.D.5
Nelson, S.D.6
-
121
-
-
0030894527
-
Disposition of amodiaquine and related antimalarial agents in human neutrophils: implications for drug design
-
Naisbitt D.J., Ruscoe J.E., Williams D., O'Neill P.M., Pirmohamed M., Park B.K. Disposition of amodiaquine and related antimalarial agents in human neutrophils: implications for drug design. Journal of Pharmacology and Experimental Therapeutics 1997, 280:884-893.
-
(1997)
Journal of Pharmacology and Experimental Therapeutics
, vol.280
, pp. 884-893
-
-
Naisbitt, D.J.1
Ruscoe, J.E.2
Williams, D.3
O'Neill, P.M.4
Pirmohamed, M.5
Park, B.K.6
-
122
-
-
0022655075
-
Amodiaquine induced agranulocytosis and liver damage
-
Neftel K.A., Woodtly W., Schmid M., Frick P.G., Fehr J. Amodiaquine induced agranulocytosis and liver damage. British Medical Journal 1986, 292:721-723.
-
(1986)
British Medical Journal
, vol.292
, pp. 721-723
-
-
Neftel, K.A.1
Woodtly, W.2
Schmid, M.3
Frick, P.G.4
Fehr, J.5
-
123
-
-
0017176137
-
Isoniazid and iproniazid: activation of metabolites to toxic intermediates in man and rat
-
Nelson S.D., Mitchell J.R., Timbrell J.A., Snodgrass W.R., Corcoran G.B. Isoniazid and iproniazid: activation of metabolites to toxic intermediates in man and rat. Science 1976, 193:901-903.
-
(1976)
Science
, vol.193
, pp. 901-903
-
-
Nelson, S.D.1
Mitchell, J.R.2
Timbrell, J.A.3
Snodgrass, W.R.4
Corcoran, G.B.5
-
124
-
-
0028784410
-
A retrospective evaluation of adverse reactions to trimethoprim-sulphonamide combinations in dogs and cats
-
Noli C., Koeman J.P., Willemse T. A retrospective evaluation of adverse reactions to trimethoprim-sulphonamide combinations in dogs and cats. Veterinary Quarterly 1995, 17:123-128.
-
(1995)
Veterinary Quarterly
, vol.17
, pp. 123-128
-
-
Noli, C.1
Koeman, J.P.2
Willemse, T.3
-
125
-
-
0036066905
-
Advantages of glutamate dehydrogenase as a blood biomarker of acute hepatic injury in rats
-
O'Brien P.J., Slaughter M.R., Polley S.R., Kramer K. Advantages of glutamate dehydrogenase as a blood biomarker of acute hepatic injury in rats. Laboratory Animals 2002, 36:313-321.
-
(2002)
Laboratory Animals
, vol.36
, pp. 313-321
-
-
O'Brien, P.J.1
Slaughter, M.R.2
Polley, S.R.3
Kramer, K.4
-
126
-
-
53549100467
-
Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose
-
Obach R.S., Kalgutkar A.S., Soglia J.R., Zhao S.X. Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose. Chemical Research in Toxicology 2008, 21:1814-1822.
-
(2008)
Chemical Research in Toxicology
, vol.21
, pp. 1814-1822
-
-
Obach, R.S.1
Kalgutkar, A.S.2
Soglia, J.R.3
Zhao, S.X.4
-
127
-
-
34347250517
-
Troglitazone-induced hepatic necrosis in an animal model of silent genetic mitochondrial abnormalities
-
Ong M.M.K., Latchoumycandane C., Boelsterli U.A. Troglitazone-induced hepatic necrosis in an animal model of silent genetic mitochondrial abnormalities. Toxicological Sciences 2007, 97:205-213.
-
(2007)
Toxicological Sciences
, vol.97
, pp. 205-213
-
-
Ong, M.M.K.1
Latchoumycandane, C.2
Boelsterli, U.A.3
-
128
-
-
31344460017
-
Nimesulide-induced hepatic mitochondrial injury in heterozygous Sod2+/- mice
-
Ong M.M.K., Wang A.S., Leow K.Y., Khoo Y.M., Boelsterli U.A. Nimesulide-induced hepatic mitochondrial injury in heterozygous Sod2+/- mice. Free Radical Biology & Medicine 2006, 40:420-429.
-
(2006)
Free Radical Biology & Medicine
, vol.40
, pp. 420-429
-
-
Ong, M.M.K.1
Wang, A.S.2
Leow, K.Y.3
Khoo, Y.M.4
Boelsterli, U.A.5
-
129
-
-
0033553628
-
Protective effect of Phyllanthus Fraternus against carbon tetrachloride-induced mitochondrial dysfunction
-
Padma P., Setty O.H. Protective effect of Phyllanthus Fraternus against carbon tetrachloride-induced mitochondrial dysfunction. Life Sciences 1999, 64:2411-2417.
-
(1999)
Life Sciences
, vol.64
, pp. 2411-2417
-
-
Padma, P.1
Setty, O.H.2
-
130
-
-
1642540100
-
Serious adverse cutaneous and hepatic toxicities associated with nevirapine use by non-HIV-infected individuals
-
Patel S.M., Johnson S., Belknap S.M., Chan J., Sha B.E., Bennett C. Serious adverse cutaneous and hepatic toxicities associated with nevirapine use by non-HIV-infected individuals. Journal of Acquired Immune Deficiency Syndromes 2004, 35:120-125.
-
(2004)
Journal of Acquired Immune Deficiency Syndromes
, vol.35
, pp. 120-125
-
-
Patel, S.M.1
Johnson, S.2
Belknap, S.M.3
Chan, J.4
Sha, B.E.5
Bennett, C.6
-
131
-
-
0023729115
-
Altered disposition of propylthiouracil in cats with hyperthyroidism
-
Peterson M.E., Aucoin D.P., Davis C.A., Graves T.K. Altered disposition of propylthiouracil in cats with hyperthyroidism. Research in Veterinary Science 1988, 45:1-3.
-
(1988)
Research in Veterinary Science
, vol.45
, pp. 1-3
-
-
Peterson, M.E.1
Aucoin, D.P.2
Davis, C.A.3
Graves, T.K.4
-
132
-
-
0021346525
-
Propylthiouracil-associated hemolytic anemia, thrombocytopenia, and antinuclear antibodies in cats with hyperthyroidism
-
Peterson M.E., Hurvitz A.I., Leib M.S., Cavanagh P.G., Dutton R.E. Propylthiouracil-associated hemolytic anemia, thrombocytopenia, and antinuclear antibodies in cats with hyperthyroidism. Journal of the American Veterinary Medical Association 1984, 184:806-808.
-
(1984)
Journal of the American Veterinary Medical Association
, vol.184
, pp. 806-808
-
-
Peterson, M.E.1
Hurvitz, A.I.2
Leib, M.S.3
Cavanagh, P.G.4
Dutton, R.E.5
-
133
-
-
77949320495
-
Pharmacogenetics of idiosyncratic adverse drug reactions
-
Pirmohamed M. Pharmacogenetics of idiosyncratic adverse drug reactions. Handbook of Experimental Pharmacology 2010, 196:477-491.
-
(2010)
Handbook of Experimental Pharmacology
, vol.196
, pp. 477-491
-
-
Pirmohamed, M.1
-
134
-
-
0032419597
-
Safety profile of nevirapine, a nonnucleoside reverse transcriptase inhibitor for the treatment of human immunodeficiency virus infection
-
Pollard R.B., Robinson P., Dransfield K. Safety profile of nevirapine, a nonnucleoside reverse transcriptase inhibitor for the treatment of human immunodeficiency virus infection. Clinical Therapeutics 1998, 20:1071-1092.
-
(1998)
Clinical Therapeutics
, vol.20
, pp. 1071-1092
-
-
Pollard, R.B.1
Robinson, P.2
Dransfield, K.3
-
135
-
-
0034495201
-
Effects of antipsychotic drugs on cytokine networks
-
Pollmächer T., Haack M., Schuld A., Kraus T., Hinze-Selch D. Effects of antipsychotic drugs on cytokine networks. Journal of Psychiatric Research 2000, 34:369-382.
-
(2000)
Journal of Psychiatric Research
, vol.34
, pp. 369-382
-
-
Pollmächer, T.1
Haack, M.2
Schuld, A.3
Kraus, T.4
Hinze-Selch, D.5
-
136
-
-
33748995692
-
Study of the sequence of events involved in nevirapine-induced skin rash in Brown Norway rats
-
Popovic M., Caswell J.L., Mannargudi B., Shenton J.M., Uetrecht J.P. Study of the sequence of events involved in nevirapine-induced skin rash in Brown Norway rats. Chemical Research in Toxicology 2006, 19:1205-1214.
-
(2006)
Chemical Research in Toxicology
, vol.19
, pp. 1205-1214
-
-
Popovic, M.1
Caswell, J.L.2
Mannargudi, B.3
Shenton, J.M.4
Uetrecht, J.P.5
-
138
-
-
0027257146
-
Treating activated CD4+Tcells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice
-
Quddus J., Johnson K.J., Gavalchin J., Amento E.P., Chrisp C.E., Yung R., et al. Treating activated CD4+Tcells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice. Journal of Clinical Investigations 1993, 92:38-53.
-
(1993)
Journal of Clinical Investigations
, vol.92
, pp. 38-53
-
-
Quddus, J.1
Johnson, K.J.2
Gavalchin, J.3
Amento, E.P.4
Chrisp, C.E.5
Yung, R.6
-
139
-
-
79952007967
-
The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity
-
Ramachandran A., Lebofsky M., Weinman S.A., Jaeschke H. The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity. Toxicology and Applied Pharmacology 2011, 251:226-233.
-
(2011)
Toxicology and Applied Pharmacology
, vol.251
, pp. 226-233
-
-
Ramachandran, A.1
Lebofsky, M.2
Weinman, S.A.3
Jaeschke, H.4
-
140
-
-
0035663287
-
A protective role for cyclooxygenase-2 in drug-induced liver injury in mice
-
Reilly T.P., Brady J.N., Marchick M.R., Bourdi M., George J.W., Radonovich M.F., et al. A protective role for cyclooxygenase-2 in drug-induced liver injury in mice. Chemical Research in Toxicology 2001, 14:1620-1628.
-
(2001)
Chemical Research in Toxicology
, vol.14
, pp. 1620-1628
-
-
Reilly, T.P.1
Brady, J.N.2
Marchick, M.R.3
Bourdi, M.4
George, J.W.5
Radonovich, M.F.6
-
141
-
-
0033102629
-
Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse
-
Remmen H.V., Salvador C., Yang H., Huang T.T., Epstein C.J., Richardson A. Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse. Archives of Biochemistry and Biophysics 1999, 363:91-97.
-
(1999)
Archives of Biochemistry and Biophysics
, vol.363
, pp. 91-97
-
-
Remmen, H.V.1
Salvador, C.2
Yang, H.3
Huang, T.T.4
Epstein, C.J.5
Richardson, A.6
-
142
-
-
0017734770
-
Halothane hepatotoxicity: enhancement by polychlorinated biphenyl pretreatment
-
Reynolds E.S., Moslen M.T. Halothane hepatotoxicity: enhancement by polychlorinated biphenyl pretreatment. Anesthesiology 1977, 47:19-27.
-
(1977)
Anesthesiology
, vol.47
, pp. 19-27
-
-
Reynolds, E.S.1
Moslen, M.T.2
-
143
-
-
0024434180
-
Evidence for an intercellular covalent reaction essential in antigen-specific T cell activation
-
Rhodes J. Evidence for an intercellular covalent reaction essential in antigen-specific T cell activation. Journal of Immunology 1989, 143:1482-1489.
-
(1989)
Journal of Immunology
, vol.143
, pp. 1482-1489
-
-
Rhodes, J.1
-
144
-
-
0025666735
-
Evidence for impared T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis
-
Richardson B., Scheinbart L., Strahler J., Gross L., Hanash S., Johnson M. Evidence for impared T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis. Arthritis Rheumatism 1990, 33:1665-1673.
-
(1990)
Arthritis Rheumatism
, vol.33
, pp. 1665-1673
-
-
Richardson, B.1
Scheinbart, L.2
Strahler, J.3
Gross, L.4
Hanash, S.5
Johnson, M.6
-
145
-
-
0026741293
-
Phenotypic and functional similarities between 5 azacytidine-treated T cells and a T cell subset in patients with active systemic lupus erythematosus
-
Richardson B.C., Strahler J.R., Pivirotto T.S., Quddus J., Bayliss G.E., Gross L.A., et al. Phenotypic and functional similarities between 5 azacytidine-treated T cells and a T cell subset in patients with active systemic lupus erythematosus. Arthritis Rheumatism 1992, 35:647-662.
-
(1992)
Arthritis Rheumatism
, vol.35
, pp. 647-662
-
-
Richardson, B.C.1
Strahler, J.R.2
Pivirotto, T.S.3
Quddus, J.4
Bayliss, G.E.5
Gross, L.A.6
-
146
-
-
0035998280
-
Interaction between human serum albumin and the felbamate metabolites 4-hydroxy-5-phenyl-[1,3]oxazinan-2-one and 2-phenylpropenal
-
Roller S.G., Dieckhaus C.M., Santos W.L., Sofia R.D., Macdonald T.L. Interaction between human serum albumin and the felbamate metabolites 4-hydroxy-5-phenyl-[1,3]oxazinan-2-one and 2-phenylpropenal. Chemical Research in Toxicology 2002, 15:815-824.
-
(2002)
Chemical Research in Toxicology
, vol.15
, pp. 815-824
-
-
Roller, S.G.1
Dieckhaus, C.M.2
Santos, W.L.3
Sofia, R.D.4
Macdonald, T.L.5
-
147
-
-
17644414511
-
Drug-induced lupus
-
Rubin R.L. Drug-induced lupus. Toxicology 2005, 209:135-147.
-
(2005)
Toxicology
, vol.209
, pp. 135-147
-
-
Rubin, R.L.1
-
148
-
-
0028928935
-
IgG but not other classes of anti-[(H2A-H2B)-DNA] is an early sign of procainamide induced lupus
-
Rubin R.L., Burlingame R.W., Arnott J.E., Totoritis M.C., McNally E.M., Johnson A.D. IgG but not other classes of anti-[(H2A-H2B)-DNA] is an early sign of procainamide induced lupus. Journal of Immunology 1995, 154:2483-2493.
-
(1995)
Journal of Immunology
, vol.154
, pp. 2483-2493
-
-
Rubin, R.L.1
Burlingame, R.W.2
Arnott, J.E.3
Totoritis, M.C.4
McNally, E.M.5
Johnson, A.D.6
-
149
-
-
3042737420
-
Interleukin-17 regulates expression of the CXC chemokine LIX/CXCL5 in osteoblasts: implications for inflammation and neutrophil recruitment
-
Ruddy M.J., Shen F., Smith J.B., Sharma A., Gaffen S.L. Interleukin-17 regulates expression of the CXC chemokine LIX/CXCL5 in osteoblasts: implications for inflammation and neutrophil recruitment. Journal of Leukocyte Biology 2004, 76:135-144.
-
(2004)
Journal of Leukocyte Biology
, vol.76
, pp. 135-144
-
-
Ruddy, M.J.1
Shen, F.2
Smith, J.B.3
Sharma, A.4
Gaffen, S.L.5
-
150
-
-
0036341332
-
Effect of indoleamine 2,3-dioxygenase on induction of experimental autoimmune encephalomyelitis
-
Sakurai K., Zou J.-P., Tschetter J.R., Ward J.M., Shearer G.M. Effect of indoleamine 2,3-dioxygenase on induction of experimental autoimmune encephalomyelitis. Journal of Neuroimmunology 2002, 129:186-196.
-
(2002)
Journal of Neuroimmunology
, vol.129
, pp. 186-196
-
-
Sakurai, K.1
Zou, J.-P.2
Tschetter, J.R.3
Ward, J.M.4
Shearer, G.M.5
-
151
-
-
0032927195
-
Inhibition of isoniazid-induced hepatotoxicity in rabbits by pretreatment with an amidase inhibitor
-
Sarich T.C., Adams S.P., Petricca G., Wright J.M. Inhibition of isoniazid-induced hepatotoxicity in rabbits by pretreatment with an amidase inhibitor. Journal of Pharmacology and Experimental Therapeutics 1999, 289:695-702.
-
(1999)
Journal of Pharmacology and Experimental Therapeutics
, vol.289
, pp. 695-702
-
-
Sarich, T.C.1
Adams, S.P.2
Petricca, G.3
Wright, J.M.4
-
152
-
-
0029952968
-
Role of hydrazine in the mechanism of isoniazid hepatotoxicity in rabbits
-
Sarich T.C., Youssefi M., Zhou T., Adams S.P., Wall R.A., Wright J.M. Role of hydrazine in the mechanism of isoniazid hepatotoxicity in rabbits. Archives in Toxicology 1996, 70:835-840.
-
(1996)
Archives in Toxicology
, vol.70
, pp. 835-840
-
-
Sarich, T.C.1
Youssefi, M.2
Zhou, T.3
Adams, S.P.4
Wall, R.A.5
Wright, J.M.6
-
153
-
-
0035927924
-
Factors that modify penicillamine-induced autoimmunity in Brown Norway rats: failure of the Th1/Th2 paradigm
-
Sayeh E., Uetrecht J.P. Factors that modify penicillamine-induced autoimmunity in Brown Norway rats: failure of the Th1/Th2 paradigm. Toxicology 2001, 163:195-211.
-
(2001)
Toxicology
, vol.163
, pp. 195-211
-
-
Sayeh, E.1
Uetrecht, J.P.2
-
154
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
Scaffidi P., Misteli T., Bianchi M.E. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002, 418:191-195.
-
(2002)
Nature
, vol.418
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
155
-
-
0025238948
-
Immunologic consequences of taurine deficiency in cats
-
Schuller-Levis G., Mehta P.D., Rudelli R., Sturman J. Immunologic consequences of taurine deficiency in cats. Journal of Leukocyte Biology 1990, 47:321-331.
-
(1990)
Journal of Leukocyte Biology
, vol.47
, pp. 321-331
-
-
Schuller-Levis, G.1
Mehta, P.D.2
Rudelli, R.3
Sturman, J.4
-
156
-
-
84863769928
-
Identification of hydroxylaminoglutethimide as induced urinary metabolites of aminoglutethimide in C57BL/6 mice
-
Ellis Horwood Ltd, Chichester, J.W. Forrod, L.A. Damani (Eds.)
-
Seago A., Jarman M., Foster A.B., Baker M. Identification of hydroxylaminoglutethimide as induced urinary metabolites of aminoglutethimide in C57BL/6 mice. Biological Oxidation of Nitrogen in Organic Molecules 1985, 149-1563. Ellis Horwood Ltd, Chichester. J.W. Forrod, L.A. Damani (Eds.).
-
(1985)
Biological Oxidation of Nitrogen in Organic Molecules
, pp. 149-1563
-
-
Seago, A.1
Jarman, M.2
Foster, A.B.3
Baker, M.4
-
157
-
-
84863743348
-
Covalent binding of nevirapine in vitro and in vivo
-
Sharma A., Uetrecht J. Covalent binding of nevirapine in vitro and in vivo. The Toxicologist 2011, 120:323.
-
(2011)
The Toxicologist
, vol.120
, pp. 323
-
-
Sharma, A.1
Uetrecht, J.2
-
159
-
-
29644438945
-
Evidence of an immune-mediated mechanism for an idiosyncratic nevirapine-induced reaction in the female Brown Norway rat
-
Shenton J.M., Popovic M., Chen J., Masson M.J., Uetrecht J.P. Evidence of an immune-mediated mechanism for an idiosyncratic nevirapine-induced reaction in the female Brown Norway rat. Chemical Research in Toxicology 2005, 18:1799-1813.
-
(2005)
Chemical Research in Toxicology
, vol.18
, pp. 1799-1813
-
-
Shenton, J.M.1
Popovic, M.2
Chen, J.3
Masson, M.J.4
Uetrecht, J.P.5
-
160
-
-
0141624936
-
Characterization of a potential animal model of an idiosyncratic drug reaction: nevirapine-induced skin rash in the rat
-
Shenton J.M., Teranishi M., Abu-Asab M.S., Yager J.A., Uetrecht J.P. Characterization of a potential animal model of an idiosyncratic drug reaction: nevirapine-induced skin rash in the rat. Chemical Research in Toxicology 2003, 16:1078-1089.
-
(2003)
Chemical Research in Toxicology
, vol.16
, pp. 1078-1089
-
-
Shenton, J.M.1
Teranishi, M.2
Abu-Asab, M.S.3
Yager, J.A.4
Uetrecht, J.P.5
-
161
-
-
0035185411
-
Control of T-cell activation by CD4+ CD25+ suppressor T cells
-
Shevach E.M., McHugh R.S., Piccirillo C.A., Thornton A.M. Control of T-cell activation by CD4+ CD25+ suppressor T cells. Immunological Reviews 2001, 182:58-67.
-
(2001)
Immunological Reviews
, vol.182
, pp. 58-67
-
-
Shevach, E.M.1
McHugh, R.S.2
Piccirillo, C.A.3
Thornton, A.M.4
-
162
-
-
67650762537
-
Metabolism-dependent hepatotoxicity of amodiaquine in glutathione-depleted mice
-
Shimizu S., Atsumi R., Itokawa K., Iwasaki M., Aoki T., Ono C., et al. Metabolism-dependent hepatotoxicity of amodiaquine in glutathione-depleted mice. Archives in Toxicology 2009, 83:701-707.
-
(2009)
Archives in Toxicology
, vol.83
, pp. 701-707
-
-
Shimizu, S.1
Atsumi, R.2
Itokawa, K.3
Iwasaki, M.4
Aoki, T.5
Ono, C.6
-
163
-
-
0017190666
-
An animal model of hepatotoxicity associated with halothane anesthesia
-
Sipes I.G., Brown B.R. An animal model of hepatotoxicity associated with halothane anesthesia. Anesthesiology 1976, 45:622-628.
-
(1976)
Anesthesiology
, vol.45
, pp. 622-628
-
-
Sipes, I.G.1
Brown, B.R.2
-
164
-
-
34547621062
-
Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis
-
Siraki A.G., Bonini M.G., Jiang J., Ehrenshaft M., Mason R.P. Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. Chemical Research in Toxicology 2007, 20:1038-1045.
-
(2007)
Chemical Research in Toxicology
, vol.20
, pp. 1038-1045
-
-
Siraki, A.G.1
Bonini, M.G.2
Jiang, J.3
Ehrenshaft, M.4
Mason, R.P.5
-
165
-
-
0038650658
-
Mechanisms of troglitazone hepatotoxicity
-
Smith M.T. Mechanisms of troglitazone hepatotoxicity. Chemical Research in Toxicology 2003, 16:679-687.
-
(2003)
Chemical Research in Toxicology
, vol.16
, pp. 679-687
-
-
Smith, M.T.1
-
166
-
-
0030886878
-
Study of oxidative-stress in isoniazid-rifampicin induced hepatic injury in young rats
-
Sodhi C.P., Rana S.V., Mehta S.K., Vaiphei K., Attari S., Mehta S. Study of oxidative-stress in isoniazid-rifampicin induced hepatic injury in young rats. Drug and Chemical Toxicology 1997, 20:255-269.
-
(1997)
Drug and Chemical Toxicology
, vol.20
, pp. 255-269
-
-
Sodhi, C.P.1
Rana, S.V.2
Mehta, S.K.3
Vaiphei, K.4
Attari, S.5
Mehta, S.6
-
167
-
-
0018892323
-
Adverse effects of d-penicillamine in rheumatoid arthritis
-
Stein H.B., Patterson A.C., Offer R.C., Atkins C.J., Teufel A., Robinson H.S. Adverse effects of d-penicillamine in rheumatoid arthritis. Annals of Internal Medicine 1980, 92:24-29.
-
(1980)
Annals of Internal Medicine
, vol.92
, pp. 24-29
-
-
Stein, H.B.1
Patterson, A.C.2
Offer, R.C.3
Atkins, C.J.4
Teufel, A.5
Robinson, H.S.6
-
168
-
-
34548161720
-
Potentiation of isoniazid-induced liver toxicity by rifampicin in a combinational therapy of antitubercular drugs (rifampicin, isoniazid and pyrazinamide) in Wistar rats: a toxicity profile study
-
Tasduq S.A., Kaiser P., Sharma S.C., Johri R.K. Potentiation of isoniazid-induced liver toxicity by rifampicin in a combinational therapy of antitubercular drugs (rifampicin, isoniazid and pyrazinamide) in Wistar rats: a toxicity profile study. Hepatology Research 2007, 37:845-853.
-
(2007)
Hepatology Research
, vol.37
, pp. 845-853
-
-
Tasduq, S.A.1
Kaiser, P.2
Sharma, S.C.3
Johri, R.K.4
-
169
-
-
0030975561
-
Identification of modified atropaldehyde mercapturic acids in rat and human urine after felbamate administration
-
Thompson C.D., Gulden P.H., Macdonald T.L. Identification of modified atropaldehyde mercapturic acids in rat and human urine after felbamate administration. Chemical Research in Toxicology 1997, 10:457-462.
-
(1997)
Chemical Research in Toxicology
, vol.10
, pp. 457-462
-
-
Thompson, C.D.1
Gulden, P.H.2
Macdonald, T.L.3
-
170
-
-
0029849184
-
Synthesis and in vitro reactivity of 3-carbamoyl-2-phenylpropionaldehyde and 2-phenylpropenal: putative reactive metabolites of felbamate
-
Thompson C.D., Kinter M.T., Macdonald T.L. Synthesis and in vitro reactivity of 3-carbamoyl-2-phenylpropionaldehyde and 2-phenylpropenal: putative reactive metabolites of felbamate. Chemical Research in Toxicology 1996, 9:1225-1229.
-
(1996)
Chemical Research in Toxicology
, vol.9
, pp. 1225-1229
-
-
Thompson, C.D.1
Kinter, M.T.2
Macdonald, T.L.3
-
171
-
-
0028802468
-
The bioactivation of amodiaquine by human polymorphonuclear leucocytes in vitro: chemical mechanisms and the effects of fluorine substitution
-
Tingle M.D., Jewell H., Maggs J.L., O'Neill P.M., Park B.K. The bioactivation of amodiaquine by human polymorphonuclear leucocytes in vitro: chemical mechanisms and the effects of fluorine substitution. Biochemical Pharmacology 1995, 50:1113-1119.
-
(1995)
Biochemical Pharmacology
, vol.50
, pp. 1113-1119
-
-
Tingle, M.D.1
Jewell, H.2
Maggs, J.L.3
O'Neill, P.M.4
Park, B.K.5
-
172
-
-
0025318090
-
D-Penicillamine-induced autoimmunity in Brown-Norway rats. Similarities with HgCl2-induced autoimmunity
-
Tournade H., Pelletier L., Pasquier R., Vial M.C., Mandet C., Druet P. d-Penicillamine-induced autoimmunity in Brown-Norway rats. Similarities with HgCl2-induced autoimmunity. Journal of Immunology 1990, 144:2985-2991.
-
(1990)
Journal of Immunology
, vol.144
, pp. 2985-2991
-
-
Tournade, H.1
Pelletier, L.2
Pasquier, R.3
Vial, M.C.4
Mandet, C.5
Druet, P.6
-
173
-
-
0033409072
-
Delayed hypersensitivity reactions to sulphonamides: syndromes, pathogenesis and management
-
Trepanier L.A. Delayed hypersensitivity reactions to sulphonamides: syndromes, pathogenesis and management. Veterinary Dermatology 1999, 10:241-248.
-
(1999)
Veterinary Dermatology
, vol.10
, pp. 241-248
-
-
Trepanier, L.A.1
-
174
-
-
3042800902
-
Idiosyncratic toxicity associated with potentiated sulfonamides in the dog
-
Trepanier L.A. Idiosyncratic toxicity associated with potentiated sulfonamides in the dog. Journal of Veterinary Pharmacology and Therapeutics 2004, 27:129-138.
-
(2004)
Journal of Veterinary Pharmacology and Therapeutics
, vol.27
, pp. 129-138
-
-
Trepanier, L.A.1
-
175
-
-
0141993052
-
Clinical findings in 40 dogs with hypersensitivity associated with administration of potentiated sulfonamides
-
Trepanier L.A., Danhof R., Toll J., Watrous D. Clinical findings in 40 dogs with hypersensitivity associated with administration of potentiated sulfonamides. Journal of Veterinary Internal Medicine 2003, 17:647-652.
-
(2003)
Journal of Veterinary Internal Medicine
, vol.17
, pp. 647-652
-
-
Trepanier, L.A.1
Danhof, R.2
Toll, J.3
Watrous, D.4
-
176
-
-
0030855768
-
Cytosolic arylamine N-acetyltransferase (NAT) deficiency in the dog and other canids due to absence of NAT genes
-
Trepanier L.A., Ray K., Winand N.J., Spielberg S.P., Cribb A.E. Cytosolic arylamine N-acetyltransferase (NAT) deficiency in the dog and other canids due to absence of NAT genes. Biochemical Pharmacology 1997, 54:73-80.
-
(1997)
Biochemical Pharmacology
, vol.54
, pp. 73-80
-
-
Trepanier, L.A.1
Ray, K.2
Winand, N.J.3
Spielberg, S.P.4
Cribb, A.E.5
-
177
-
-
0026645711
-
The role of leukocyte-generated reactive metabolites in the pathogenesis of idiosyncratic drug reactions
-
Uetrecht J. The role of leukocyte-generated reactive metabolites in the pathogenesis of idiosyncratic drug reactions. Drug Metabolism Reviews 1992, 24:299-366.
-
(1992)
Drug Metabolism Reviews
, vol.24
, pp. 299-366
-
-
Uetrecht, J.1
-
178
-
-
0036040079
-
N-oxidation of drugs associated with idiosyncratic drug reactions
-
Uetrecht J. N-oxidation of drugs associated with idiosyncratic drug reactions. Drug Metabolism Reviews 2002, 34:651-665.
-
(2002)
Drug Metabolism Reviews
, vol.34
, pp. 651-665
-
-
Uetrecht, J.1
-
179
-
-
33747126524
-
Role of animal models in the study of drug-induced hypersensitivity reactions
-
Uetrecht J. Role of animal models in the study of drug-induced hypersensitivity reactions. AAPS Journal 2005, 7:E914-921.
-
(2005)
AAPS Journal
, vol.7
-
-
Uetrecht, J.1
-
181
-
-
70449117614
-
Immunoallergic drug-induced liver injury in humans
-
Uetrecht J. Immunoallergic drug-induced liver injury in humans. Seminars in Liver Disease 2009, 29:383-392.
-
(2009)
Seminars in Liver Disease
, vol.29
, pp. 383-392
-
-
Uetrecht, J.1
-
182
-
-
0028911862
-
Oxidation of aminopyrine by hypochlorite to a reactive dication: possible implications for aminopyrine-induced agranulocytosis
-
Uetrecht J.P., Ma H.M., MacKnight E., McClelland R. Oxidation of aminopyrine by hypochlorite to a reactive dication: possible implications for aminopyrine-induced agranulocytosis. Chemical Research in Toxicology 1995, 8:226-233.
-
(1995)
Chemical Research in Toxicology
, vol.8
, pp. 226-233
-
-
Uetrecht, J.P.1
Ma, H.M.2
MacKnight, E.3
McClelland, R.4
-
183
-
-
71049174955
-
Evaluation of the potential for drug-induced liver injury based on in vitro covalent binding to human liver proteins
-
Usui T., Mise M., Hashizume T., Yabuki M., Komuro S. Evaluation of the potential for drug-induced liver injury based on in vitro covalent binding to human liver proteins. Drug Metabolism and Disposition 2009, 37:2383-2392.
-
(2009)
Drug Metabolism and Disposition
, vol.37
, pp. 2383-2392
-
-
Usui, T.1
Mise, M.2
Hashizume, T.3
Yabuki, M.4
Komuro, S.5
-
184
-
-
39849105346
-
HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz
-
Vitezica Z.G., Milpied B., Lonjou C., Borot N., Ledger T.N., Lefebvre A., et al. HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz. AIDS 2008, 22:540-541.
-
(2008)
AIDS
, vol.22
, pp. 540-541
-
-
Vitezica, Z.G.1
Milpied, B.2
Lonjou, C.3
Borot, N.4
Ledger, T.N.5
Lefebvre, A.6
-
185
-
-
0026073198
-
Oxidation of propylthiouracil to reactive metabolites by activated neutrophils: implications for agranulocytosis
-
Waldhauser L., Uetrecht J. Oxidation of propylthiouracil to reactive metabolites by activated neutrophils: implications for agranulocytosis. Drug Metabolism and Disposition 1991, 19:354-359.
-
(1991)
Drug Metabolism and Disposition
, vol.19
, pp. 354-359
-
-
Waldhauser, L.1
Uetrecht, J.2
-
186
-
-
0030566910
-
Antibodies to myeloperoxidase in propylthiouracil-induced autoimmune disease in the cat
-
Waldhauser L., Uetrecht J. Antibodies to myeloperoxidase in propylthiouracil-induced autoimmune disease in the cat. Toxicology 1996, 114:155-162.
-
(1996)
Toxicology
, vol.114
, pp. 155-162
-
-
Waldhauser, L.1
Uetrecht, J.2
-
187
-
-
33644781852
-
Microarray analysis of lipopolysaccharide potentiation of trovafloxacin-induced liver injury in rats suggests a role for proinflammatory chemokines and neutrophils
-
Waring J.F., Liguori M.J., Luyendyk J.P., Maddox J.F., Ganey P.E., Stachlewitz R.F. Microarray analysis of lipopolysaccharide potentiation of trovafloxacin-induced liver injury in rats suggests a role for proinflammatory chemokines and neutrophils. Journal of Pharmacology and Experimental Therapeutics 2005, 316:1080-1087.
-
(2005)
Journal of Pharmacology and Experimental Therapeutics
, vol.316
, pp. 1080-1087
-
-
Waring, J.F.1
Liguori, M.J.2
Luyendyk, J.P.3
Maddox, J.F.4
Ganey, P.E.5
Stachlewitz, R.F.6
-
188
-
-
85004773685
-
The predictive value of the lymphocyte transformation test in isoniazid-associated hepatitis
-
Warrington R.J., McPhilips-Feener S., Rutherford W.J. The predictive value of the lymphocyte transformation test in isoniazid-associated hepatitis. Clinical Allergy 1982, 12:217-222.
-
(1982)
Clinical Allergy
, vol.12
, pp. 217-222
-
-
Warrington, R.J.1
McPhilips-Feener, S.2
Rutherford, W.J.3
-
189
-
-
0018150811
-
Evaluation of isoniazid-associated hepatitis by immunological tests
-
Warrington R.J., Tse K.S., Gorski B.A., Schwenk R., Sehon A.H. Evaluation of isoniazid-associated hepatitis by immunological tests. Clinical & Experimental Immunology 1978, 32:97-104.
-
(1978)
Clinical & Experimental Immunology
, vol.32
, pp. 97-104
-
-
Warrington, R.J.1
Tse, K.S.2
Gorski, B.A.3
Schwenk, R.4
Sehon, A.H.5
-
190
-
-
0033938971
-
Induction of metabolism-dependent and -independent neutrophil apoptosis by clozapine
-
Williams D.P., Pirmohamed M., Naisbitt D.J., Uetrecht J.P., Park B.K. Induction of metabolism-dependent and -independent neutrophil apoptosis by clozapine. Molecular Pharmacology 2000, 58:207-216.
-
(2000)
Molecular Pharmacology
, vol.58
, pp. 207-216
-
-
Williams, D.P.1
Pirmohamed, M.2
Naisbitt, D.J.3
Uetrecht, J.P.4
Park, B.K.5
-
192
-
-
77950865023
-
Generation of T cell responses targeting the reactive metabolite of halothane in mice
-
You Q., Cheng L., Ju C. Generation of T cell responses targeting the reactive metabolite of halothane in mice. Toxicology Letters 2010, 194:79-85.
-
(2010)
Toxicology Letters
, vol.194
, pp. 79-85
-
-
You, Q.1
Cheng, L.2
Ju, C.3
-
193
-
-
33845681113
-
Role of neutrophils in a mouse model of halothane-induced liver injury
-
You Q., Cheng L., Reilly T.P., Wegmann D., Ju C. Role of neutrophils in a mouse model of halothane-induced liver injury. Hepatology 2006, 44:1421-1431.
-
(2006)
Hepatology
, vol.44
, pp. 1421-1431
-
-
You, Q.1
Cheng, L.2
Reilly, T.P.3
Wegmann, D.4
Ju, C.5
-
194
-
-
85027929582
-
Toxicogenomics of nevirapine-associated cutaneous and hepatic adverse events among populations of African, Asian, and European descent
-
Yuan J., Guo S., Hall D., Cammett A.M., Jayadev S., Distel M., et al. Toxicogenomics of nevirapine-associated cutaneous and hepatic adverse events among populations of African, Asian, and European descent. Aids 2011, 25:1271-1280.
-
(2011)
Aids
, vol.25
, pp. 1271-1280
-
-
Yuan, J.1
Guo, S.2
Hall, D.3
Cammett, A.M.4
Jayadev, S.5
Distel, M.6
-
195
-
-
0030985363
-
Mechanisms of drug induced lupus IV: comparison of procainamide and hydralazine with analogs in vitro and in vivo
-
Yung R., Chang S., Hemati N., Johnson K., Richardson B. Mechanisms of drug induced lupus IV: comparison of procainamide and hydralazine with analogs in vitro and in vivo. Arthritis & Rheumatism 1997, 40:1436-1443.
-
(1997)
Arthritis & Rheumatism
, vol.40
, pp. 1436-1443
-
-
Yung, R.1
Chang, S.2
Hemati, N.3
Johnson, K.4
Richardson, B.5
-
196
-
-
0038645801
-
Mechanisms of drug induced lupus II: T cells overexpressing lymphocyte function-associated antigen 1 become autroreactive and cause lupuslike disease in syngeneic mice
-
Yung R., Powers D., Johnson K., Amento E., Carr D., Laing T., et al. Mechanisms of drug induced lupus II: T cells overexpressing lymphocyte function-associated antigen 1 become autroreactive and cause lupuslike disease in syngeneic mice. Journal of Clinical Investgations 1996, 97:2866-2871.
-
(1996)
Journal of Clinical Investgations
, vol.97
, pp. 2866-2871
-
-
Yung, R.1
Powers, D.2
Johnson, K.3
Amento, E.4
Carr, D.5
Laing, T.6
-
197
-
-
0028986033
-
Mechanisms of drug induced lupus I: cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo
-
Yung R.L., Quddus J., Chrisp C.E., Johnson K.J., Richardson B.C. Mechanisms of drug induced lupus I: cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo. Journal of Immunology 1995, 154:3025-3035.
-
(1995)
Journal of Immunology
, vol.154
, pp. 3025-3035
-
-
Yung, R.L.1
Quddus, J.2
Chrisp, C.E.3
Johnson, K.J.4
Richardson, B.C.5
-
198
-
-
79953099798
-
Involvement of T helper 17 cells in d-penicillamine-induced autoimmune disease in Brown Norway rats
-
Zhu X., Li J., Liu F., Uetrecht J.P. Involvement of T helper 17 cells in d-penicillamine-induced autoimmune disease in Brown Norway rats. Toxicological Sciences 2011, 120:331-338.
-
(2011)
Toxicological Sciences
, vol.120
, pp. 331-338
-
-
Zhu, X.1
Li, J.2
Liu, F.3
Uetrecht, J.P.4
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