Mitochondrial involvement in drug-induced hepatic injury

Chemico-Biological Interactions

Volumn 163, Issue 1-2, 2006, Pages 145-159

  Kass, George E N ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Acetaminophen; Apoptosis; Bcl 2; Bile salt; Calcium; Caspase; ER stress; Ethanol; Glycogen synthase kinase; Necrosis; Oncosis; Paracetamol

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ALCOHOL; APOPTOSIS INDUCING FACTOR; BH3 PROTEIN; BONGKREKIC ACID; CARBON TETRACHLORIDE; CASPASE INHIBITOR; CHLORPROMAZINE; CYCLOPHILIN; CYCLOPHILIN D; CYCLOSPORIN A; CYTOCHROME C; ESTRADIOL 17 GLUCURONIDE; HALOTHANE; ISONIAZID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PARACETAMOL; PERHEXILINE; PHENYTOIN; PROTEIN BAK; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TACROLIMUS; TAMOXIFEN; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; X LINKED INHIBITOR OF APOPTOSIS;

ARTICLE; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CHOLESTASIS; DRUG HYPERSENSITIVITY; DRUG METABOLISM; FATTY LIVER; HUMAN; IMMUNE MEDIATED INJURY; LIVER CELL DAMAGE; LIVER MITOCHONDRION; LIVER PROTECTION; LIVER TOXICITY; MEMBRANE DAMAGE; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL TOXICITY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ACETAMINOPHEN; ANIMALS; CELL DEATH; DRUG-INDUCED LIVER INJURY; HUMANS; LIVER DISEASES; MITOCHONDRIA, LIVER; MITOCHONDRIAL MEMBRANES;

EID: 33749989821     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2006.06.007     Document Type: Article

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