Halothane hepatitis in Iran: A review of 59 cases

World Journal of Gastroenterology

Volumn 14, Issue 34, 2008, Pages 5322-5326

  Eghtesadi Araghi, Payam ^a   Sohrabpour, Amir Ali ^b   Vahedi, Homayoon ^a   Saberi Firoozi, Mehdi ^b  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Anesthesia; Drug induced; Halothane; Hepatitis; Inhalation

Indexed keywords

HALOTHANE; INHALATION ANESTHETIC AGENT;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BRAIN DISEASE; CHOLECYSTECTOMY; CORONARY ARTERY BYPASS GRAFT; DRUG EXPOSURE; ESTHETIC SURGERY; FEMALE; GENERAL ANESTHESIA; HUMAN; IRAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; OBESITY; RETROSPECTIVE STUDY; RISK FACTOR; TOXIC HEPATITIS; WEIGHT REDUCTION; ADOLESCENT; CLINICAL TRIAL; DRUG CONTRAINDICATION; MIDDLE AGED; MULTICENTER STUDY; PREGNANCY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANESTHETICS, INHALATION; FEMALE; HALOTHANE; HEPATITIS, TOXIC; HUMANS; IRAN; MALE; MIDDLE AGED; PREGNANCY; RETROSPECTIVE STUDIES; RISK FACTORS; YOUNG ADULT;

EID: 63149108256     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.14.5322     Document Type: Article

References (50)

1. Johnstone M. The human cardiovascular response to fluothane anaesthesia. 1956. Br J Anaesth 1998; 80: 396-405; discussion 395
2. Burnap TK, Galla SJ, Vandam LD. Anesthetic, circulatory and respiratory effects of fluothane. Anesthesiology 1958; 19: 307-320
3. Postoperative death after fluothane. Anesthesiology 1958; 19: 562-563
4. Brody GL, Sweet RB. Halothane anesthesia as a possible cause of massive hepatic necrosis. Anesthesiology 1963; 24: 29-37
5. Bunker JP, Blumenfeld CM. Liver necrosis after halothane anesthesia. Cause or coincidence? N Engl J Med 1963; 268: 531-534
6. Lindenbaum J, Leifer E. Hepatic necrosis associated with halothane anesthesia. N Engl J Med 1963; 268: 525-530
7. Temple RL, Cote RA, Gorens SW. Massive hepatic necrosis following general anesthesia. Anesth Analg 1962; 41: 586-592
8. Brown BR Jr, Gandolfi AJ. Adverse effects of volatile anaesthetics. Br J Anaesth 1987; 59: 14-23
9. Summary of the national Halothane Study. Possible association between halothane anesthesia and postoperative hepatic necrosis. JAMA 1966; 197: 775-788
10. Ray DC, Drummond GB. Halothane hepatitis. Br J Anaesth 1991; 67: 84-99
11. Peralta R, Poterack KA, Guzofski S. Halothane Hepatotoxicity. Last modified date: May 25, 2006. Available from URL: http://www.emedicine.com
12. Allan LG, Hussey AJ, Howie J, Beckett GJ, Smith AF, Hayes JD, Drummond GB. Hepatic glutathione S-transferase release after halothane anaesthesia: open randomised comparison with isoflurane. Lancet 1987; 1: 771-774
13. Hussey AJ, Aldridge LM, Paul D, Ray DC, Beckett GJ, Allan LG. Plasma glutathione S-transferase concentration as a measure of hepatocellular integrity following a single general anaesthetic with halothane, enflurane or isoflurane. Br J Anaesth 1988; 60: 130-135
14. Voigt MD, Workman B, Lombard C, Kirsch RE. Halothane hepatitis in a South African population - frequency and the influence of gender and ethnicity. S Afr Med J 1997; 87: 882-885
15. Daghfous R, el Aidli S, Sfaxi M, Daghfous M, Kastalli S, Srairi S, Loueslati MH, Belkahia C. [Halothane-induced hepatitis. 8 case reports] Tunis Med 2003; 81: 874-878
16. Otedo AE. Halothane induced hepatitis: case report. East Afr Med J 2004; 81: 538-539
17. Kumar GP, Bhat VJ, Sowdi V. Fulminant hepatic failure following halothane anaesthesia. J Clin Forensic Med 2005; 12: 271-273
18. Rodes J, Bruguera M. The uses of error: iatrogenic hepatitis. Lancet 2001; 357: 791
19. The "Halothane" will be replaced with newer anesthetic drugs in Iran. Date Accessed: July 17, 2008. Available from URL: http://www.reporter.ir/archives/86/10/005402.php
20. Benjamin SB, Goodman ZD, Ishak KG, Zimmerman HJ, Irey NS. The morphologic spectrum of halothane-induced hepatic injury: analysis of 77 cases. Hepatology 1985; 5: 1163-1171
21. Neuberger J, Williams R. Halothane anaesthesia and liver damage. Br Med J (Clin Res Ed) 1984; 289: 1136-1139
22. Bottiger LE, Dalen E, Hallen B. Halothane-induced liver damage: an analysis of the material reported to the Swedish Adverse Drug Reaction Committee, 1966-1973. Acta Anaesthesiol Scand 1976; 20: 40-46
23. Carney FM, Van Dyke RA. Halothane hepatitis: a critical review. Anesth Analg 1972; 51: 135-160
24. Walton B, Simpson BR, Strunin L, Doniach D, Perrin J, Appleyard AJ. Unexplained hepatitis following halothane. Br Med J 1976; 1: 1171-1176
25. Peters RL, Edmondson HA, Reynolds TB, Meister JC, Curpey TJ. Hepatic necrosis associated with halothane anesthesia. Am J Med 1969; 47: 748-764
26. Bentley JB, Vaughan RW, Gandolfi AJ, Cork RC. Halothane biotransformation in obese and nonobese patients. Anesthesiology 1982; 57: 94-97
27. Boland LL, Folsom AR, Rosamond WD. Hyperinsulinemia, dyslipidemia, and obesity as risk factors for hospitalized gallbladder disease. A prospective study. Ann Epidemiol 2002; 12: 131-140
28. Grunhage F, Lammert F. Gallstone disease. Pathogenesis of gallstones: A genetic perspective. Best Pract Res Clin Gastroenterol 2006; 20: 997-1015
29. Wild SH, Byrne CD. ABC of obesity. Risk factors for diabetes and coronary heart disease. BMJ 2006; 333: 1009-1011
30. Franzosi MG. Should we continue to use BMI as a cardiovascular risk factor? Lancet 2006; 368: 624-625
31. Cousins MJ, Plummer JL, Hall PD. Risk factors for halothane hepatitis. Aust N Z J Surg 1989; 59: 5-14
32. Gelman S, Fowler KC, Smith LR. Liver circulation and function during isoflurane and halothane anesthesia. Anesthesiology 1984; 61: 726-730
33. Hursh D, Gelman S, Bradley EL Jr. Hepatic oxygen supply during halothane or isoflurane anesthesia in guinea pigs. Anesthesiology 1987; 67: 701-706
34. Gelman S, Rimerman V, Fowler KC, Bishop SP, Bradley EL Jr. The effect of halothane, isoflurane, and blood loss on hepatotoxicity and hepatic oxygen availability in phenobarbital-pretreated hypoxic rats. Anesth Analg 1984; 63: 965-972
35. Hughes RL, Campbell D, Fitch W. Effects of enflurane and halothane on liver blood flow and oxygen consumption in the greyhound. Br J Anaesth 1980; 52: 1079-1086
36. Seltzer JL, Goldberg ME, Larijani GE, Ritter DE, Starsnic MA, Stahl GL, Lefer AM. Prostacyclin mediation of vasodilation following mesenteric traction. Anesthesiology 1988; 68: 514-518
37. D'Ancona G, Baillot R, Poirier B, Dagenais F, de Ibarra JI, Bauset R, Mathieu P, Doyle D. Determinants of gastrointestinal complications in cardiac surgery. Tex Heart Inst J 2003; 30: 280-285
38. Zacharias A, Schwann TA, Parenteau GL, Riordan CJ, Durham SJ, Engoren M, Fenn-Buderer N, Habib RH. Predictors of gastrointestinal complications in cardiac surgery. Tex Heart Inst J 2000; 27: 93-99
39. Nimmo WS, Thompson PG, Prescott LF. Microsomal enzyme induction after halothane anaesthesia. Br J Clin Pharmacol 1981; 12: 433-434
40. St Haxholdt O, Loft S, Clemmensen A, Hjortso E. Increased hepatic microsomal activity after halothane anaesthesia in children. Anaesthesia 1986; 41: 579-581
41. Neuberger JM. Halothane and hepatitis. Incidence, predisposing factors and exposure guidelines. Drug Saf 1990; 5: 28-38
42. Inman WH, Mushin WW. Jaundice after repeated exposure to halothane: an analysis of Reports to the Committee on Safety of Medicines. Br Med J 1974; 1: 5-10
43. Inman WH, Mushin WW. Jaundice after repeated exposure to halothane: a further analysis of reports to the Committee on Safety of Medicines. Br Med J 1978; 2: 1455-1456
44. Neuberger J, Williams R. Halothane hepatitis. Dig Dis 1988; 6: 52-64
45. Nomura F, Hatano H, Ohnishi K, Akikusa B, Okuda K. Effects of anticonvulsant agents on halothane-induced liver injury in human subjects and experimental animals. Hepatology 1986; 6: 952-956
46. Hoft RH, Bunker JP, Goodman HI, Gregory PB. Halothane hepatitis in three pairs of closely related women. N Engl J Med 1981; 304: 1023-1024
47. Bjornsson E, Jerlstad P, Bergqvist A, Olsson R. Fulminant drug-induced hepatic failure leading to death or liver transplantation in Sweden. Scand J Gastroenterol 2005; 40: 1095-1101
48. Neuberger J. Halothane hepatitis. Eur J Gastroenterol Hepatol 1998; 10: 631-633
49. Moult PJ, Sherlock S. Halothane-related hepatitis. A clinical study of twenty-six cases. Q J Med 1975; 44: 99-114
50. Bjornsson E, Olsson R. Suspected drug-induced liver fatalities reported to the WHO database. Dig Liver Dis 2006; 38: 33-38