Nimesulide-induced hepatic mitochondrial injury in heterozygous Sod2 +/- mice

Free Radical Biology and Medicine

Volumn 40, Issue 3, 2006, Pages 420-429

  Ong, Michie M K ^a   Wang, Audrey S ^a   Leow, Koon Yeow ^a   Khoo, Yok Moi ^a   Boelsterli, Urs A ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Apoptosis; Free radicals; Idiosyncratic liver injury; Mitochondrial stress; NSAIDs; Oxidative stress; Superoxide dismutase

Indexed keywords

ACONITATE HYDRATASE; ALANINE AMINOTRANSFERASE; CASPASE 3; CYTOCHROME C; MANGANESE SUPEROXIDE DISMUTASE; NIMESULIDE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; GENOTYPE; HETEROZYGOSITY; HISTOPATHOLOGY; IN VITRO STUDY; LIVER CELL; LIVER CELL DAMAGE; LIVER CYTOSOL; LIVER MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; WESTERN BLOTTING;

ACONITATE HYDRATASE; ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CASPASES; CYTOCHROMES C; CYTOSOL; FEMALE; GLUTATHIONE; HETEROZYGOTE; IN SITU NICK-END LABELING; MALE; MICE; MICE, KNOCKOUT; MITOCHONDRIA, LIVER; OXIDATIVE STRESS; SULFONAMIDES; SUPEROXIDE DISMUTASE; SUPEROXIDES;

ANIMALIA;

EID: 31344460017     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2005.08.038     Document Type: Article

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