Study of oxidative-stress in isoniazid-rifampicin induced hepatic injury in young rats

Drug and Chemical Toxicology

Volumn 20, Issue 3, 1997, Pages 255-269

  Sodhi, C P ^a   Rana, S V ^a,b   Mehta, S K ^a   Vaiphei, K ^a   Attari, S ^a   Mehta, S ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

^b House No 137   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; ISONIAZID; RIFAMPICIN; SUPEROXIDE DISMUTASE; THIOL DERIVATIVE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; CONTROLLED STUDY; ENZYME ACTIVITY; INTRAPERITONEAL DRUG ADMINISTRATION; LIPID PEROXIDATION; LIPID STORAGE; LIVER; LIVER INJURY; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; RAT;

ANIMALIA;

EID: 0030886878     PISSN: 01480545     EISSN: None     Source Type: Journal    
DOI: 10.3109/01480549709003881     Document Type: Article

References (31)

1. D.E. Snider, M.W. Long, F.S. Cross and L.S. Farer. Six months isoniazid-rifampicin therapy for pulmonary tuberculosis. Report of a United States Health Service Cooperative trial. Am. Rev. Respir. Dis. 129, 573 (1984).
2. M.A. Steele, R.F. Burk and R.M. DesPrez. Toxic hepatitis with isoniazid and rifampicin. A metaanalysis. Chest. 99, 465 (1991).
3. R. Parthasarthy, G.R. Sarma, B. Janardhanam, P. Ramachandra n T. Santha, P.R. Sivasubramanian. et al. Hepatic toxicity in South Indian patients during treatment of tuberculosis with short-course regimens containing isoniazid, rifampicin and pyrazinamide. Tuberc. 67, 99 (1986).
4. P.C. Ramachandran. Chemotherapy of tubercular meningitis with isoniazid plus rifampicin. Klnterim findings in a trial in children. Ind. J. Tuberc. 27, 54 (1980).
5. P.S. Rugmini, S. Mehta. Hepatotoxicity of isoniazid and rifampicin in children. Ind. Pediatr. 21, 119 (1984).
6. R.J. O'Brien, M.W. Long, S.C. Floy, M.A. Lyle and D.E. Jr. Snider. Hepatotoxicity from isoniazid and rifampicin among children treated for tuberculosis. Pediatr. 72, 491 (1983).
7. S.D. Nelson, J.R. Mitchell, J.A. Timbrell, W.R. Snodgrass and G.B. Corcoran III. Isoniazid and lproniazid : Activation of metabolites to toxic intermediate in man and rat. Science. 192, 901 (1976).
8. C. Immanuel, K. Jayasankar, A.S.L. Narayana and R. Sarma. Self induction of rifampicin metabolism in man. Indian J. Med. Res. 82, 381 (1985).
9. A. Piriou, A. Jacqueson, J.M. Warnet and J.R. Claude. Enzyme induction with high doses of rifampicin in Wistar rats. Toxicol. Lett. 17, 301 (1983).
10. 4-induced lipid peroxidation and hepatotoxicity. Chem. Biol. Interact. 55, 327 (1985).
11. E.S., Reynolds and R.E. Ree. Liver parenchymal cell injury. VII. Membrane denaturation following carbon tetrachloride. La. Invest. 25, 269 (1971).
12. E. Beutler, O. Duron and B.M. Kelly. Improved method for the determination of blood glutathione. J. Lab. Clin. Med. 61, 882 (1963).
13. J. Sedlak and R.H. Lindsay. Estimation of total, protein-bound and non-protein sulfhydryl group in tissue with Ellman's reagent. Anal. Biochem. 25, 192 (1968).
14. 3 activated peroxidation of lipids in microsomes and mitochondria. Biochem. Biophys. Res. Commun. 14, 323 (1964).
15. Y. Kono. Generation of superoxide radical during autoxidation of hydroxylamine and an assay for Superoxide dismutase. Arch. Biochem. Biophys. 186, 189 (1978).
16. H. Luck. Catalases. In, Methods in Enzymatic Analysis. Academic press, N.Y. and London, 1971, p. 886.
17. I. Carlberg, and B. Mannervik. Purification by affinity chromatography of yeast glutathione reductase, the enzyme responsible for the NADPH dependent reduction of the mixed disulfide of CoA and glutathione. Biochem. Biophys. Acta. 484, 268 (1977).
18. L. Flohe, and W.A. Gungler. Assay of glutathione peroxidase. Methods Enzymol. 105, 114 (1984).
19. W.H. Habig, M.J. Pabst and W.B. Jakoby. Glutathione-S-transferases. The first step in mercapturic acid formation. J. Biol. Chem. 249, 7130 (1974).
20. O.H. Lowry, N.J. Rosenbrough, A.L. Farr and R.J. Randall. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265 (1951).
21. B. Halliwell. Reactive oxygen species in living systems : Source, biochemistry and role in human disease. Am. J. Med. 91, 145 (1991).
22. R. Zand, S.D. Nelson, J.T. Slattery, K.E. Thummel, T.F. Kalhorn, S.P. Adams and J.M. Wright. Inhibition and induction of cytochrome P450 2E1-catalyzed by isoniazid in humans. Clin. Pharmacol. Therapeut. 54, 142 (1993).
23. J.A. Brent, and B.. Rumack. Role of free radicals in toxic hepatic injury. I. Free radical biochemistry. Clin. Toxicol. 31, 139 (1993).
24. E.R. Stadtman, and C.N. Oliver. Meta-catalyzed oxidation of protein, physiological consequences. J. Biol. Chem. 266, 2005 (1991).
25. K. Ito, K. Yamamoto, and S. Kawanishi. Manganese mediated oxidative damage of cellular and isolated DNA by isoniazid and related hydrazines : Non-fenton-type hydroxyl radical formation. Biochem. 31, 11606 (1992).
26. I.S. Jamal, and J.C. Smith. Effects of cadmium treatment on selenium dependent and selenium independent glutathione peroxidase activities and lipid peroxidation in the kidney and liver of rats maintained on various levels of dietary selenium. Arch. Toxicol. 58, 102 (1985).
27. J. Blum, and I. Fridovich. Inactivation of glutathione peroxidase by superoxide radical. Arch. Biochem. Biophys. 240, 500 (1985).
28. J.D. Wallin, G. Clifton, and W. Kaplocoitz. The effect of phenobarbital, probenecid and diethyl maleate on the pharmacokinetics and biliary excretion of ethacrynic acid in the rat. J. Pharmacol. Exp. Therapeut. 205, 471 (1988).
29. G.L. Mandell and M.A. Sande. Antimicrobial agents. Pharmacological basis of therapeutic. In Goodman, L.S., Gillman, A. (eds). McMillan Publishers, 1991, p. 1047.
30. C.P. Sodhi, S.V. Rana, S.K. Mehta, K. Vaiphei, S. Attri, S. Thakur and S. Mehta, Study of oxidative-stress in isoniazid induced hepatic injury in young rats with and without protein-energy malnutrition. J. Biochem. Toxicol. (1996) accepted.
31. C-P. Sodhi, S.V. Rana, S. Mehta, K. Vaiphei, and S.K. Mehta. Study of oxidative-stress in rifampicin induced hepatic injuiry in young rats with and without protein-energy malnutrition. Nutrition (under considerations).