Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 12, 2004, Pages 4180-4185

  Martin, Annalise M ^a   Nolan, David ^a   Gaudieri, Silvana ^a,b   Almeida, Coral Ann ^a   Nolan, Richard ^c   James, Ian ^a   Carvalho, Filipa ^a   Phillips, Elizabeth ^d   Christiansen, Frank T ^b,c   Purcell, Anthony W ^e   McCluskey, James ^e   Mallal, Simon ^a,c  

^a MURDOCH UNIVERSITY   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c ROYAL PERTH HOSPITAL   (Australia)

^d SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Ancestral haplotype; Human leukocyte antigen; Microsatellite; Single nucleotide polymorphism

Indexed keywords

ABACAVIR; CD8 ANTIGEN; HEAT SHOCK PROTEIN 70; HLA B ANTIGEN; MICROSATELLITE DNA; TUMOR NECROSIS FACTOR;

ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; AUSTRALIA; C4A6 GENE; CONTROLLED STUDY; DRUG HYPERSENSITIVITY; GENE; GENE CLUSTER; GENE EXPRESSION; GENE LOCUS; GENE MAPPING; GENETIC MARKER; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; HAPLOTYPE; HLA B 5701 GENE; HLA SYSTEM; HSP70 HOM GENE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOPATHOLOGY; IMMUNOPHENOTYPING; LYMPHOCYTE DEPLETION; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MEGT1 GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN VARIANT; RECOMBINANT GENE; SINGLE NUCLEOTIDE POLYMORPHISM; T LYMPHOCYTE SUBPOPULATION;

CHROMOSOME MAPPING; DIDEOXYNUCLEOSIDES; DRUG HYPERSENSITIVITY; GENETIC MARKERS; HAPLOTYPES; HLA-B ANTIGENS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR SEQUENCE DATA; PREVALENCE; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 12144287198     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0307067101     Document Type: Article

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