Amino acid adduct formation by the nevirapine metabolite, 12-Hydroxynevirapine- A Possible Factor in Nevirapine Toxicity

Chemical Research in Toxicology

Volumn 23, Issue 5, 2010, Pages 888-899

  Antunes, Alexandra M M ^a   Godinho, Ana L A ^a   Martins, Inê L ^a   Justino, Gonçalo C ^a   Beland, Frederick A ^b   Marques, M Matilde ^a  

^a INSTITUTO SUPERIOR TÉCNICO   (Portugal)

^b NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

12 HYDROXYNEVIRAPINE; ACETYLCYSTEINE; ARGININE; CYSTEINE; GLUTATHIONE; HISTIDINE; NEVIRAPINE; TRYPTOPHAN; UNCLASSIFIED DRUG; VALINE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHILD; CLINICAL TRIAL; DRUG METABOLISM; ESTERIFICATION; HUMAN; MASS SPECTROMETRY; MULTICENTER STUDY; NONHUMAN; PROTEIN MODIFICATION; PROTON NUCLEAR MAGNETIC RESONANCE;

ACETYLCYSTEINE; AMINO ACIDS; GLUTATHIONE; HISTIDINE; HUMANS; MESYLATES; NEVIRAPINE; REVERSE TRANSCRIPTASE INHIBITORS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRYPTOPHAN;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 77952359731     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx900443z     Document Type: Article

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