-
1
-
-
0031685620
-
TGF-beta signal transduction
-
J. Massague TGF-beta signal transduction Annu. Rev. Biochem. 67 1998 753 791
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 753-791
-
-
Massague, J.1
-
2
-
-
80054020133
-
Morphogen gradients: From generation to interpretation
-
K.W. Rogers, and A.F. Schier Morphogen gradients: from generation to interpretation Annu. Rev. Cell Dev. Biol. 27 2011 377 407
-
(2011)
Annu. Rev. Cell Dev. Biol.
, vol.27
, pp. 377-407
-
-
Rogers, K.W.1
Schier, A.F.2
-
3
-
-
81955164757
-
Spatiotemporal mechanisms of morphogen gradient interpretation
-
M. Nahmad, and A.D. Lander Spatiotemporal mechanisms of morphogen gradient interpretation Curr. Opin. Genet. Dev. 21 2011 726 731
-
(2011)
Curr. Opin. Genet. Dev.
, vol.21
, pp. 726-731
-
-
Nahmad, M.1
Lander, A.D.2
-
5
-
-
77957259882
-
Robust generation and decoding of morphogen gradients
-
N. Barkai, and B.Z. Shilo Robust generation and decoding of morphogen gradients Cold Spring Harb Perspect Biol 1 2009 a001990
-
(2009)
Cold Spring Harb Perspect Biol
, vol.1
, pp. 001990
-
-
Barkai, N.1
Shilo, B.Z.2
-
6
-
-
0037439630
-
Making sense of latent TGFbeta activation
-
J.P. Annes, J.S. Munger, and D.B. Rifkin Making sense of latent TGFbeta activation J. Cell Sci. 116 2003 217 224
-
(2003)
J. Cell Sci.
, vol.116
, pp. 217-224
-
-
Annes, J.P.1
Munger, J.S.2
Rifkin, D.B.3
-
7
-
-
0034604110
-
Role of transforming growth factor beta in human disease
-
G.C. Blobe, W.P. Schiemann, and H.F. Lodish Role of transforming growth factor beta in human disease N. Engl. J. Med. 342 2000 1350 1358
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 1350-1358
-
-
Blobe, G.C.1
Schiemann, W.P.2
Lodish, H.F.3
-
8
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Y. Shi, and J. Massague Mechanisms of TGF-beta signaling from cell membrane to the nucleus Cell 113 2003 685 700
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
9
-
-
58149269185
-
Endocytic regulation of TGF-beta signaling
-
Y.G. Chen Endocytic regulation of TGF-beta signaling Cell Res. 19 2009 58 70
-
(2009)
Cell Res.
, vol.19
, pp. 58-70
-
-
Chen, Y.G.1
-
12
-
-
65449144474
-
Transforming growth factor beta depletion is the primary determinant of Smad signaling kinetics
-
D.C. Clarke, M.L. Brown, R.A. Erickson, Y. Shi, and X. Liu Transforming growth factor beta depletion is the primary determinant of Smad signaling kinetics Mol. Cell. Biol. 29 2009 2443 2455
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 2443-2455
-
-
Clarke, D.C.1
Brown, M.L.2
Erickson, R.A.3
Shi, Y.4
Liu, X.5
-
13
-
-
79957536131
-
Quantitative analysis of transient and sustained transforming growth factor-beta signaling dynamics
-
Z. Zi, Z. Feng, D.A. Chapnick, M. Dahl, D. Deng, E. Klipp, A. Moustakas, and X. Liu Quantitative analysis of transient and sustained transforming growth factor-beta signaling dynamics Molecular systems biology 7 2011 492
-
(2011)
Molecular Systems Biology
, vol.7
, pp. 492
-
-
Zi, Z.1
Feng, Z.2
Chapnick, D.A.3
Dahl, M.4
Deng, D.5
Klipp, E.6
Moustakas, A.7
Liu, X.8
-
14
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-beta family signalling
-
R. Derynck, and Y.E. Zhang Smad-dependent and Smad-independent pathways in TGF-beta family signalling Nature 425 2003 577 584
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
15
-
-
24944497786
-
Non-Smad TGF-beta signals
-
A. Moustakas, and C.-H. Heldin Non-Smad TGF-beta signals J. Cell Sci. 118 2005 3573 3584
-
(2005)
J. Cell Sci.
, vol.118
, pp. 3573-3584
-
-
Moustakas, A.1
Heldin, C.-H.2
-
18
-
-
49849103199
-
Decoding the quantitative nature of TGF-beta/Smad signaling
-
D.C. Clarke, and X. Liu Decoding the quantitative nature of TGF-beta/Smad signaling Trends Cell Biol. 18 2008 430 442
-
(2008)
Trends Cell Biol.
, vol.18
, pp. 430-442
-
-
Clarke, D.C.1
Liu, X.2
-
19
-
-
27644583784
-
Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor beta-dependent nuclear accumulation of Smads
-
B. Schmierer, and C.S. Hill Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor beta-dependent nuclear accumulation of Smads Mol. Cell. Biol. 25 2005 9845 9858
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 9845-9858
-
-
Schmierer, B.1
Hill, C.S.2
-
21
-
-
79952643760
-
Network news: Innovations in 21st century systems biology
-
A.P. Arkin, and D.V. Schaffer Network news: innovations in 21st century systems biology Cell 144 2011 844 849
-
(2011)
Cell
, vol.144
, pp. 844-849
-
-
Arkin, A.P.1
Schaffer, D.V.2
-
23
-
-
65549170041
-
Quantitative modeling and analysis of the transforming growth factor beta signaling pathway
-
S.W. Chung, F.L. Miles, R.A. Sikes, C.R. Cooper, M.C. Farach-Carson, and B.A. Ogunnaike Quantitative modeling and analysis of the transforming growth factor beta signaling pathway Biophys. J. 96 2009 1733 1750
-
(2009)
Biophys. J.
, vol.96
, pp. 1733-1750
-
-
Chung, S.W.1
Miles, F.L.2
Sikes, R.A.3
Cooper, C.R.4
Farach-Carson, M.C.5
Ogunnaike, B.A.6
-
24
-
-
33845424529
-
A rate equation approach to elucidate the kinetics and robustness of the TGF-beta pathway
-
P. Melke, H. Jonsson, E. Pardali, P. ten Dijke, and C. Peterson A rate equation approach to elucidate the kinetics and robustness of the TGF-beta pathway Biophys. J. 91 2006 4368 4380
-
(2006)
Biophys. J.
, vol.91
, pp. 4368-4380
-
-
Melke, P.1
Jonsson, H.2
Pardali, E.3
Ten Dijke, P.4
Peterson, C.5
-
25
-
-
44349125602
-
Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system
-
B. Schmierer, A.L. Tournier, P.A. Bates, and C.S. Hill Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system Proc. Nat. Acad. Sci. U.S.A. 105 2008 6608 6613
-
(2008)
Proc. Nat. Acad. Sci. U.S.A.
, vol.105
, pp. 6608-6613
-
-
Schmierer, B.1
Tournier, A.L.2
Bates, P.A.3
Hill, C.S.4
-
26
-
-
33645754505
-
Signal processing in the TGF-beta superfamily ligand-receptor network
-
J.M. Vilar, R. Jansen, and C. Sander Signal processing in the TGF-beta superfamily ligand-receptor network PLoS Comput. Biol. 2 2006 e3
-
(2006)
PLoS Comput. Biol.
, vol.2
, pp. 3
-
-
Vilar, J.M.1
Jansen, R.2
Sander, C.3
-
27
-
-
81255184468
-
Trafficking coordinate description of intracellular transport control of signaling networks
-
J.M. Vilar, and L. Saiz Trafficking coordinate description of intracellular transport control of signaling networks Biophys. J. 101 2011 2315 2323
-
(2011)
Biophys. J.
, vol.101
, pp. 2315-2323
-
-
Vilar, J.M.1
Saiz, L.2
-
28
-
-
84857373534
-
Dynamics and feedback loops in the transforming growth factor beta signaling pathway
-
K. Wegner Dynamics and feedback loops in the transforming growth factor beta signaling pathway Biophys. Chem. 162 2012 22 34
-
(2012)
Biophys. Chem.
, vol.162
, pp. 22-34
-
-
Wegner, K.1
-
29
-
-
41549094989
-
Constraint-based modeling and kinetic analysis of the Smad dependent TGF-beta signaling pathway
-
Z. Zi, and E. Klipp Constraint-based modeling and kinetic analysis of the Smad dependent TGF-beta signaling pathway PLoS ONE 2 2007 e936
-
(2007)
PLoS ONE
, vol.2
, pp. 936
-
-
Zi, Z.1
Klipp, E.2
-
30
-
-
84934438238
-
Measuring the absolute abundance of the Smad transcription factors using quantitative immunoblotting
-
D.C. Clarke, and X. Liu Measuring the absolute abundance of the Smad transcription factors using quantitative immunoblotting Methods Mol. Biol. 647 2010 357 376
-
(2010)
Methods Mol. Biol.
, vol.647
, pp. 357-376
-
-
Clarke, D.C.1
Liu, X.2
-
31
-
-
0032612065
-
Measuring dynamic cell volume in situ by confocal microscopy
-
R.J. Errington, and N.S. White Measuring dynamic cell volume in situ by confocal microscopy Methods Mol. Biol. 122 1999 315 340
-
(1999)
Methods Mol. Biol.
, vol.122
, pp. 315-340
-
-
Errington, R.J.1
White, N.S.2
-
32
-
-
0242574982
-
Parameter estimation in biochemical pathways: A comparison of global optimization methods
-
C.G. Moles, P. Mendes, and J.R. Banga Parameter estimation in biochemical pathways: a comparison of global optimization methods Genome Res. 13 2003 2467 2474
-
(2003)
Genome Res.
, vol.13
, pp. 2467-2474
-
-
Moles, C.G.1
Mendes, P.2
Banga, J.R.3
-
33
-
-
79953317637
-
SBML-PET-MPI: A parallel parameter estimation tool for Systems Biology Markup Language based models
-
Z. Zi SBML-PET-MPI: a parallel parameter estimation tool for Systems Biology Markup Language based models Bioinformatics 27 2011 1028 1029
-
(2011)
Bioinformatics
, vol.27
, pp. 1028-1029
-
-
Zi, Z.1
-
34
-
-
0026442926
-
Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm
-
J.B. Green, H.V. New, and J.C. Smith Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm Cell 71 1992 731 739
-
(1992)
Cell
, vol.71
, pp. 731-739
-
-
Green, J.B.1
New, H.V.2
Smith, J.C.3
-
35
-
-
34548684135
-
Cellular signaling is potentially regulated by cell density in receptor trafficking networks
-
Z. Zi, and E. Klipp Cellular signaling is potentially regulated by cell density in receptor trafficking networks FEBS Lett. 581 2007 4589 4595
-
(2007)
FEBS Lett.
, vol.581
, pp. 4589-4595
-
-
Zi, Z.1
Klipp, E.2
-
36
-
-
0029976245
-
Receptor-mediated effects on ligand availability influence relative mitogenic potencies of epidermal growth factor and transforming growth factor alpha
-
C.C. Reddy, A. Wells, and D.A. Lauffenburger Receptor-mediated effects on ligand availability influence relative mitogenic potencies of epidermal growth factor and transforming growth factor alpha J. Cell. Physiol. 166 1996 512 522
-
(1996)
J. Cell. Physiol.
, vol.166
, pp. 512-522
-
-
Reddy, C.C.1
Wells, A.2
Lauffenburger, D.A.3
-
37
-
-
71449121678
-
Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor
-
H. Shankaran, D.L. Ippolito, W.B. Chrisler, H. Resat, N. Bollinger, L.K. Opresko, and H.S. Wiley Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor Mol. Systems Biol. 5 2009 332
-
(2009)
Mol. Systems Biol.
, vol.5
, pp. 332
-
-
Shankaran, H.1
Ippolito, D.L.2
Chrisler, W.B.3
Resat, H.4
Bollinger, N.5
Opresko, L.K.6
Wiley, H.S.7
-
38
-
-
0037007226
-
Balancing the activation state of the endothelium via two distinct TGF-beta type i receptors
-
M.J. Goumans, G. Valdimarsdottir, S. Itoh, A. Rosendahl, P. Sideras, and P. ten Dijke Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors EMBO J. 21 2002 1743 1753
-
(2002)
EMBO J.
, vol.21
, pp. 1743-1753
-
-
Goumans, M.J.1
Valdimarsdottir, G.2
Itoh, S.3
Rosendahl, A.4
Sideras, P.5
Ten Dijke, P.6
-
39
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
-
C.J. Marshall Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation Cell 80 1995 179 185
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
40
-
-
80555135917
-
Regulation of primary response genes
-
T. Fowler, R. Sen, and A.L. Roy Regulation of primary response genes Mol. Cell 44 2011 348 360
-
(2011)
Mol. Cell
, vol.44
, pp. 348-360
-
-
Fowler, T.1
Sen, R.2
Roy, A.L.3
-
41
-
-
0038548187
-
Attenuation of the TGF-beta-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-beta-induced growth arrest
-
F.J. Nicolas, and C.S. Hill Attenuation of the TGF-beta-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-beta-induced growth arrest Oncogene 22 2003 3698 3711
-
(2003)
Oncogene
, vol.22
, pp. 3698-3711
-
-
Nicolas, F.J.1
Hill, C.S.2
-
42
-
-
79951798852
-
The inhibitory effect of ginsan on TGF-beta mediated fibrotic process
-
J.Y. Ahn, M.H. Kim, M.J. Lim, S. Park, S.L. Lee, Y.S. Yun, and J.Y. Song The inhibitory effect of ginsan on TGF-beta mediated fibrotic process J. Cell. Physiol. 226 2011 1241 1247
-
(2011)
J. Cell. Physiol.
, vol.226
, pp. 1241-1247
-
-
Ahn, J.Y.1
Kim, M.H.2
Lim, M.J.3
Park, S.4
Lee, S.L.5
Yun, Y.S.6
Song, J.Y.7
-
43
-
-
0028170226
-
Mechanism of activation of the TGF-beta receptor
-
J.L. Wrana, L. Attisano, R. Wieser, F. Ventura, and J. Massague Mechanism of activation of the TGF-beta receptor Nature 370 1994 341 347
-
(1994)
Nature
, vol.370
, pp. 341-347
-
-
Wrana, J.L.1
Attisano, L.2
Wieser, R.3
Ventura, F.4
Massague, J.5
-
44
-
-
0036670339
-
Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity
-
G.J. Inman, F.J. Nicolas, and C.S. Hill Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity Mol. Cell 10 2002 283 294
-
(2002)
Mol. Cell
, vol.10
, pp. 283-294
-
-
Inman, G.J.1
Nicolas, F.J.2
Hill, C.S.3
-
45
-
-
13444263549
-
Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling
-
C. Le Roy, and J.L. Wrana Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling Nat. Rev. Mol. Cell Biol. 6 2005 112 126
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 112-126
-
-
Le Roy, C.1
Wrana, J.L.2
-
46
-
-
0036272313
-
Internalization-dependent and -independent requirements for transforming growth factor beta receptor signaling via the Smad pathway
-
S.G. Penheiter, H. Mitchell, N. Garamszegi, M. Edens, J.J. Dore Jr., and E.B. Leof Internalization-dependent and -independent requirements for transforming growth factor beta receptor signaling via the Smad pathway Mol. Cell. Biol. 22 2002 4750 4759
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4750-4759
-
-
Penheiter, S.G.1
Mitchell, H.2
Garamszegi, N.3
Edens, M.4
Dore, Jr.J.J.5
Leof, E.B.6
-
47
-
-
0037119489
-
Transforming growth factor beta activates Smad2 in the absence of receptor endocytosis
-
Z. Lu, J.T. Murray, W. Luo, H. Li, X. Wu, H. Xu, J.M. Backer, and Y.G. Chen Transforming growth factor beta activates Smad2 in the absence of receptor endocytosis J. Biol. Chem. 277 2002 29363 29368
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 29363-29368
-
-
Lu, Z.1
Murray, J.T.2
Luo, W.3
Li, H.4
Wu, X.5
Xu, H.6
Backer, J.M.7
Chen, Y.G.8
-
48
-
-
14844307044
-
The role of internalization in transforming growth factor beta1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signaling in human mesangial cells
-
C.E. Runyan, H.W. Schnaper, and A.C. Poncelet The role of internalization in transforming growth factor beta1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signaling in human mesangial cells J. Biol. Chem. 280 2005 8300 8308
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 8300-8308
-
-
Runyan, C.E.1
Schnaper, H.W.2
Poncelet, A.C.3
-
49
-
-
0037144841
-
TGF beta receptor internalization into EEA1-enriched early endosomes: Role in signaling to Smad2
-
S. Hayes, A. Chawla, and S. Corvera TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2 J. Cell Biol. 158 2002 1239 1249
-
(2002)
J. Cell Biol.
, vol.158
, pp. 1239-1249
-
-
Hayes, S.1
Chawla, A.2
Corvera, S.3
-
50
-
-
3042707155
-
Receptor internalization-independent activation of Smad2 in activin signaling
-
Y. Zhou, S. Scolavino, S.F. Funderburk, L.F. Ficociello, X. Zhang, and A. Klibanski Receptor internalization-independent activation of Smad2 in activin signaling Mol. Endocrinol. 18 2004 1818 1826
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 1818-1826
-
-
Zhou, Y.1
Scolavino, S.2
Funderburk, S.F.3
Ficociello, L.F.4
Zhang, X.5
Klibanski, A.6
-
51
-
-
79960473010
-
Distinct role of endocytosis for Smad and non-Smad TGF-beta signaling regulation in hepatocytes
-
C. Meyer Distinct role of endocytosis for Smad and non-Smad TGF-beta signaling regulation in hepatocytes J. Hepatol. 55 2011 369 378
-
(2011)
J. Hepatol.
, vol.55
, pp. 369-378
-
-
Meyer, C.1
-
52
-
-
64049102327
-
Specific activation of mitogen-activated protein kinase by transforming growth factor-beta receptors in lipid rafts is required for epithelial cell plasticity
-
W. Zuo, and Y.G. Chen Specific activation of mitogen-activated protein kinase by transforming growth factor-beta receptors in lipid rafts is required for epithelial cell plasticity Mol. Biol. Cell 20 2009 1020 1029
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1020-1029
-
-
Zuo, W.1
Chen, Y.G.2
-
53
-
-
58149264873
-
Nucleocytoplasmic shuttling of Smad proteins
-
C.S. Hill Nucleocytoplasmic shuttling of Smad proteins Cell Res. 19 2009 36 46
-
(2009)
Cell Res.
, vol.19
, pp. 36-46
-
-
Hill, C.S.1
-
54
-
-
55649123317
-
Smad signaling dynamics: Insights from a parsimonious model
-
H. Shankaran, and H.S. Wiley Smad signaling dynamics: insights from a parsimonious model Sci Signal 1 2008 pe41
-
(2008)
Sci Signal
, vol.1
, pp. 41
-
-
Shankaran, H.1
Wiley, H.S.2
-
55
-
-
54249137797
-
Feedback loops shape cellular signals in space and time
-
O. Brandman, and T. Meyer Feedback loops shape cellular signals in space and time Science 322 2008 390 395
-
(2008)
Science
, vol.322
, pp. 390-395
-
-
Brandman, O.1
Meyer, T.2
-
56
-
-
0030611757
-
Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling
-
A. Nakao Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling Nature 389 1997 631 635
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
-
57
-
-
0031587828
-
The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling
-
H. Hayashi The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling Cell 89 1997 1165 1173
-
(1997)
Cell
, vol.89
, pp. 1165-1173
-
-
Hayashi, H.1
-
58
-
-
1642539976
-
GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type i receptor
-
W. Shi, C. Sun, B. He, W. Xiong, X. Shi, D. Yao, and X. Cao GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor J. Cell Biol. 164 2004 291 300
-
(2004)
J. Cell Biol.
, vol.164
, pp. 291-300
-
-
Shi, W.1
Sun, C.2
He, B.3
Xiong, W.4
Shi, X.5
Yao, D.6
Cao, X.7
-
59
-
-
0034517389
-
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation
-
P. Kavsak, R.K. Rasmussen, C.G. Causing, S. Bonni, H. Zhu, G.H. Thomsen, and J.L. Wrana Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation Mol. Cell 6 2000 1365 1375
-
(2000)
Mol. Cell
, vol.6
, pp. 1365-1375
-
-
Kavsak, P.1
Rasmussen, R.K.2
Causing, C.G.3
Bonni, S.4
Zhu, H.5
Thomsen, G.H.6
Wrana, J.L.7
-
60
-
-
20444474176
-
The balance between acetylation and deacetylation controls Smad7 stability
-
M. Simonsson, C.H. Heldin, J. Ericsson, and E. Gronroos The balance between acetylation and deacetylation controls Smad7 stability J. Biol. Chem. 280 2005 21797 21803
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 21797-21803
-
-
Simonsson, M.1
Heldin, C.H.2
Ericsson, J.3
Gronroos, E.4
-
61
-
-
73649085521
-
TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling
-
Y. Watanabe TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling Mol. Cell 37 2010 123 134
-
(2010)
Mol. Cell
, vol.37
, pp. 123-134
-
-
Watanabe, Y.1
-
63
-
-
0842281496
-
Ski and SnoN: Negative regulators of TGF-beta signaling
-
K. Luo Ski and SnoN: negative regulators of TGF-beta signaling Curr. Opin. Genet. Dev. 14 2004 65 70
-
(2004)
Curr. Opin. Genet. Dev.
, vol.14
, pp. 65-70
-
-
Luo, K.1
-
64
-
-
0033595704
-
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
-
S.L. Stroschein, W. Wang, S. Zhou, Q. Zhou, and K. Luo Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein Science 286 1999 771 774
-
(1999)
Science
, vol.286
, pp. 771-774
-
-
Stroschein, S.L.1
Wang, W.2
Zhou, S.3
Zhou, Q.4
Luo, K.5
-
65
-
-
0033607240
-
SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling
-
Y. Sun, X. Liu, E. Ng-Eaton, H.F. Lodish, and R.A. Weinberg SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling Proc. Nat. Acad. Sci. U.S.A. 96 1999 12442 12447
-
(1999)
Proc. Nat. Acad. Sci. U.S.A.
, vol.96
, pp. 12442-12447
-
-
Sun, Y.1
Liu, X.2
Ng-Eaton, E.3
Lodish, H.F.4
Weinberg, R.A.5
-
66
-
-
34548238145
-
Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation
-
L. Levy, M. Howell, D. Das, S. Harkin, V. Episkopou, and C.S. Hill Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation Mol. Cell. Biol. 27 2007 6068 6083
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 6068-6083
-
-
Levy, L.1
Howell, M.2
Das, D.3
Harkin, S.4
Episkopou, V.5
Hill, C.S.6
-
67
-
-
34547108879
-
Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling
-
Y. Nagano Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling J. Biol. Chem. 282 2007 20492 20501
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 20492-20501
-
-
Nagano, Y.1
-
68
-
-
0037044575
-
The IkappaB-NF-kappaB signaling module: Temporal control and selective gene activation
-
A. Hoffmann, A. Levchenko, M.L. Scott, and D. Baltimore The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation Science 298 2002 1241 1245
-
(2002)
Science
, vol.298
, pp. 1241-1245
-
-
Hoffmann, A.1
Levchenko, A.2
Scott, M.L.3
Baltimore, D.4
-
69
-
-
33745451921
-
Oscillations and variability in the p53 system
-
N. Geva-Zatorsky Oscillations and variability in the p53 system Mol. Systems Biol. 2 2006 2006 0033
-
(2006)
Mol. Systems Biol.
, vol.2
, Issue.2006
, pp. 0033
-
-
Geva-Zatorsky, N.1
-
70
-
-
56749160113
-
Design principles of biochemical oscillators
-
B. Novak, and J.J. Tyson Design principles of biochemical oscillators Nat. Rev. Mol. Cell Biol. 9 2008 981 991
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 981-991
-
-
Novak, B.1
Tyson, J.J.2
-
71
-
-
33847716712
-
Negative regulation of TGF-beta receptor/Smad signal transduction
-
S. Itoh, and P. ten Dijke Negative regulation of TGF-beta receptor/Smad signal transduction Curr. Opin. Cell Biol. 19 2007 176 184
-
(2007)
Curr. Opin. Cell Biol.
, vol.19
, pp. 176-184
-
-
Itoh, S.1
Ten Dijke, P.2
-
73
-
-
30944451715
-
The early history of TGF-beta, and a brief glimpse of its future
-
M.B. Sporn The early history of TGF-beta, and a brief glimpse of its future Cytokine Growth Factor Rev. 17 2006 3 7
-
(2006)
Cytokine Growth Factor Rev.
, vol.17
, pp. 3-7
-
-
Sporn, M.B.1
-
74
-
-
33646691720
-
Id1 is a critical mediator in TGF-beta-induced transdifferentiation of rat hepatic stellate cells
-
E. Wiercinska Id1 is a critical mediator in TGF-beta-induced transdifferentiation of rat hepatic stellate cells Hepatology 43 2006 1032 1041
-
(2006)
Hepatology
, vol.43
, pp. 1032-1041
-
-
Wiercinska, E.1
-
75
-
-
0034023371
-
Functions of mammalian Smad genes as revealed by targeted gene disruption in mice
-
M. Weinstein, X. Yang, and C. Deng Functions of mammalian Smad genes as revealed by targeted gene disruption in mice Cytokine Growth Factor Rev. 11 2000 49 58
-
(2000)
Cytokine Growth Factor Rev.
, vol.11
, pp. 49-58
-
-
Weinstein, M.1
Yang, X.2
Deng, C.3
-
76
-
-
0035827581
-
Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts
-
E. Piek Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts J. Biol. Chem. 276 2001 19945 19953
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19945-19953
-
-
Piek, E.1
-
77
-
-
26244439497
-
The endogenous ratio of Smad2 and Smad3 influences the cytostatic function of Smad3
-
S.G. Kim, H.A. Kim, H.S. Jong, J.H. Park, N.K. Kim, S.H. Hong, T.Y. Kim, and Y.J. Bang The endogenous ratio of Smad2 and Smad3 influences the cytostatic function of Smad3 Mol. Biol. Cell 16 2005 4672 4683
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 4672-4683
-
-
Kim, S.G.1
Kim, H.A.2
Jong, H.S.3
Park, J.H.4
Kim, N.K.5
Hong, S.H.6
Kim, T.Y.7
Bang, Y.J.8
-
78
-
-
77953026276
-
Roles for the type III TGF-beta receptor in human cancer
-
C.E. Gatza, S.Y. Oh, and G.C. Blobe Roles for the type III TGF-beta receptor in human cancer Cell. Signal. 22 2010 1163 1174
-
(2010)
Cell. Signal.
, vol.22
, pp. 1163-1174
-
-
Gatza, C.E.1
Oh, S.Y.2
Blobe, G.C.3
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