Attenuation of the TGF-β-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-β-induced growth arrest

Oncogene

Volumn 22, Issue 24, 2003, Pages 3698-3711

  Nicolás, Francisco J ^a,b   Hill, Caroline S ^a  

^a THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^b HOSPITAL UNIVERSITARIO MORALES MESEGUER   (Spain)

Author keywords

Cell cycle arrest; Pancreatic tumor cells; Signal duration; Smad; TGF

Indexed keywords

PROTEIN P21; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; ACTIVIN RECEPTOR 1; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; DNA BINDING PROTEIN; SMAD4 PROTEIN; SMAD4 PROTEIN, HUMAN; TGF BETA TYPE I RECEPTOR; TGF-BETA TYPE I RECEPTOR; TRANSACTIVATOR PROTEIN;

ARTICLE; CANCER INVASION; CELL CYCLE; CELL GROWTH; CELL NUCLEUS; CELL PROLIFERATION; CORRELATION ANALYSIS; EPITHELIUM CELL; GENE EXPRESSION; GENE FUNCTION; HUMAN; HUMAN CELL; PANCREAS TUMOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR CELL LINE; CELL CULTURE; CELL DIVISION; DRUG EFFECT; GENETIC TRANSCRIPTION; PATHOLOGY; PHYSIOLOGY;

ACTIVIN RECEPTORS, TYPE I; CELL CYCLE; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA-BINDING PROTEINS; HUMANS; PANCREATIC NEOPLASMS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SMAD4 PROTEIN; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED;

EID: 0038548187     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206420     Document Type: Article

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