Dynamics and feedback loops in the transforming growth factor β signaling pathway

Biophysical Chemistry

Volumn 162, Issue , 2012, Pages 22-34

  Wegner, Katja ^a   Bachmann, Anastasia ^b   Schad, Jan Ulrich ^c   Lucarelli, Philippe ^d   Sahle, Sven ^c   Nickel, Peter ^d   Meyer, Christoph ^b   Klingmüller, Ursula ^d   Dooley, Steven ^b   Kummer, Ursula ^c  

^a UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Modeling; Negative and positive feedback; Oscillation; Simulation; Smad signaling

Indexed keywords

CELL PROTEIN; SKI PROTEIN; SMAD7 PROTEIN; SMURF1 PROTEIN; SMURF2 PROTEIN; SNON PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANALYTICAL PARAMETERS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL NUCLEUS; CELL SURFACE; CONTROLLED STUDY; FEEDBACK SYSTEM; GENE EXPRESSION; LIVER CELL; MALE; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; SAMPLING; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE, TUMOR; CELLS, CULTURED; COMPUTER SIMULATION; HEPATOCYTES; MALE; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UBIQUITIN-PROTEIN LIGASES;

EID: 84857373534     PISSN: 03014622     EISSN: 18734200     Source Type: Journal    
DOI: 10.1016/j.bpc.2011.12.003     Document Type: Article

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