-
1
-
-
33646950265
-
PPM1A functions as a Smad phosphatase to terminate TGFβ signaling
-
Lin X., et al. PPM1A functions as a Smad phosphatase to terminate TGFβ signaling. Cell 125 (2006) 915-928
-
(2006)
Cell
, vol.125
, pp. 915-928
-
-
Lin, X.1
-
2
-
-
0036670339
-
Nucleocytoplasmic shuttling of Smads 2, 3 and 4 permits sensing of TGF-β receptor activity
-
Inman G.J., et al. Nucleocytoplasmic shuttling of Smads 2, 3 and 4 permits sensing of TGF-β receptor activity. Mol. Cell 10 (2002) 283-294
-
(2002)
Mol. Cell
, vol.10
, pp. 283-294
-
-
Inman, G.J.1
-
3
-
-
21244489290
-
Gene expression profiling demonstrates that TGF-β1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-β signaling
-
Karlsson G., et al. Gene expression profiling demonstrates that TGF-β1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-β signaling. Physiol. Genomics 21 (2005) 396-403
-
(2005)
Physiol. Genomics
, vol.21
, pp. 396-403
-
-
Karlsson, G.1
-
4
-
-
24344483878
-
Smad4 dependency defines two classes of transforming growth factor (TGF-β) target genes and distinguishes TGF-β-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses
-
Levy L., and Hill C.S. Smad4 dependency defines two classes of transforming growth factor (TGF-β) target genes and distinguishes TGF-β-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses. Mol. Cell. Biol. 25 (2005) 8108-8125
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 8108-8125
-
-
Levy, L.1
Hill, C.S.2
-
5
-
-
0041836308
-
Hierarchical model of gene regulation by transforming growth factor β
-
Yang Y.C., et al. Hierarchical model of gene regulation by transforming growth factor β. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 10269-10274
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 10269-10274
-
-
Yang, Y.C.1
-
6
-
-
0028359376
-
Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor β and activin
-
Carcamo J., et al. Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor β and activin. Mol. Cell. Biol. 14 (1994) 3810-3821
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 3810-3821
-
-
Carcamo, J.1
-
7
-
-
24944497786
-
Non-Smad TGF-β signals
-
Moustakas A., and Heldin C.H. Non-Smad TGF-β signals. J. Cell Sci. 118 (2005) 3573-3584
-
(2005)
J. Cell Sci.
, vol.118
, pp. 3573-3584
-
-
Moustakas, A.1
Heldin, C.H.2
-
8
-
-
35048875855
-
TGF-β signaling: a tale of two responses
-
Rahimi R.A., and Leof E.B. TGF-β signaling: a tale of two responses. J. Cell. Biochem. 102 (2007) 593-608
-
(2007)
J. Cell. Biochem.
, vol.102
, pp. 593-608
-
-
Rahimi, R.A.1
Leof, E.B.2
-
9
-
-
34249775225
-
Cross-talk between the bone morphogenetic protein pathway and other major signaling pathways results in tightly regulated cell-specific outcomes
-
Herpin A., and Cunningham C. Cross-talk between the bone morphogenetic protein pathway and other major signaling pathways results in tightly regulated cell-specific outcomes. FEBS J. 274 (2007) 2977-2985
-
(2007)
FEBS J.
, vol.274
, pp. 2977-2985
-
-
Herpin, A.1
Cunningham, C.2
-
11
-
-
0023865059
-
Peptide growth factors are multifunctional
-
Sporn M.B., and Roberts A.B. Peptide growth factors are multifunctional. Nature 332 (1988) 217-219
-
(1988)
Nature
, vol.332
, pp. 217-219
-
-
Sporn, M.B.1
Roberts, A.B.2
-
12
-
-
0033566915
-
Multiple roles of bone morphogenetic protein signaling in the regulation of cortical cell number and phenotype
-
Mabie P.C., et al. Multiple roles of bone morphogenetic protein signaling in the regulation of cortical cell number and phenotype. J. Neurosci. 19 (1999) 7077-7088
-
(1999)
J. Neurosci.
, vol.19
, pp. 7077-7088
-
-
Mabie, P.C.1
-
13
-
-
2342496439
-
Transforming growth factor type β induces monocyte chemotaxis and growth factor production
-
Wahl S.M., et al. Transforming growth factor type β induces monocyte chemotaxis and growth factor production. Proc. Natl. Acad. Sci. U. S. A. 84 (1987) 5788-5792
-
(1987)
Proc. Natl. Acad. Sci. U. S. A.
, vol.84
, pp. 5788-5792
-
-
Wahl, S.M.1
-
14
-
-
0023104031
-
Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor β
-
Postlethwaite A.E., et al. Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor β. J. Exp. Med. 165 (1987) 251-256
-
(1987)
J. Exp. Med.
, vol.165
, pp. 251-256
-
-
Postlethwaite, A.E.1
-
15
-
-
0035950105
-
Morphogen gradient interpretation
-
Gurdon J.B., and Bourillot P.Y. Morphogen gradient interpretation. Nature 413 (2001) 797-803
-
(2001)
Nature
, vol.413
, pp. 797-803
-
-
Gurdon, J.B.1
Bourillot, P.Y.2
-
16
-
-
0342674048
-
Type β transforming growth factor: a bifunctional regulator of cellular growth
-
Roberts A.B., et al. Type β transforming growth factor: a bifunctional regulator of cellular growth. Proc. Natl. Acad. Sci. U. S. A. 82 (1985) 119-123
-
(1985)
Proc. Natl. Acad. Sci. U. S. A.
, vol.82
, pp. 119-123
-
-
Roberts, A.B.1
-
17
-
-
0027176133
-
Biphasic effect of transforming growth factor-β 1 on in vitro angiogenesis
-
Pepper M.S., et al. Biphasic effect of transforming growth factor-β 1 on in vitro angiogenesis. Exp. Cell Res. 204 (1993) 356-363
-
(1993)
Exp. Cell Res.
, vol.204
, pp. 356-363
-
-
Pepper, M.S.1
-
18
-
-
0022471924
-
Transforming growth factor type β: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro
-
Roberts A.B., et al. Transforming growth factor type β: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc. Natl. Acad. Sci. U. S. A. 83 (1986) 4167-4171
-
(1986)
Proc. Natl. Acad. Sci. U. S. A.
, vol.83
, pp. 4167-4171
-
-
Roberts, A.B.1
-
19
-
-
0023025366
-
Transforming growth factor-β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix
-
Ignotz R.A., and Massague J. Transforming growth factor-β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J. Biol. Chem. 261 (1986) 4337-4345
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 4337-4345
-
-
Ignotz, R.A.1
Massague, J.2
-
20
-
-
0022976357
-
Enhanced production and extracellular deposition of the endothelial-type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-β
-
Laiho M., et al. Enhanced production and extracellular deposition of the endothelial-type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-β. J. Cell Biol. 103 (1986) 2403-2410
-
(1986)
J. Cell Biol.
, vol.103
, pp. 2403-2410
-
-
Laiho, M.1
-
21
-
-
0026442926
-
Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm
-
Green J.B., et al. Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm. Cell 71 (1992) 731-739
-
(1992)
Cell
, vol.71
, pp. 731-739
-
-
Green, J.B.1
-
22
-
-
0034997337
-
BMP7 controls collecting tubule cell proliferation and apoptosis via Smad1-dependent and -independent pathways
-
Piscione T.D., et al. BMP7 controls collecting tubule cell proliferation and apoptosis via Smad1-dependent and -independent pathways. Am. J. Physiol. Renal Physiol. 280 (2001) F19-F33
-
(2001)
Am. J. Physiol. Renal Physiol.
, vol.280
-
-
Piscione, T.D.1
-
23
-
-
49849089628
-
Genetic disruptions within the murine genome reveal numerous roles of the Smad gene family in development, disease, and cancer
-
ten Dijke P., and Heldin C.H. (Eds), Springer
-
Weinstein M., and Deng C.-X. Genetic disruptions within the murine genome reveal numerous roles of the Smad gene family in development, disease, and cancer. In: ten Dijke P., and Heldin C.H. (Eds). Smad Signal Transduction: Smads in Proliferation, Differentiation and Disease Vol 5 (2006), Springer 151-176
-
(2006)
Smad Signal Transduction: Smads in Proliferation, Differentiation and Disease
, vol.5
, pp. 151-176
-
-
Weinstein, M.1
Deng, C.-X.2
-
24
-
-
0033625416
-
Functional analysis of the TGF-β receptor/Smad pathway through gene ablation in mice
-
Goumans M.J., and Mummery C. Functional analysis of the TGF-β receptor/Smad pathway through gene ablation in mice. Int. J. Dev. Biol. 44 (2000) 253-265
-
(2000)
Int. J. Dev. Biol.
, vol.44
, pp. 253-265
-
-
Goumans, M.J.1
Mummery, C.2
-
25
-
-
0038548187
-
Attenuation of the TGF-β-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-β-induced growth arrest
-
Nicolas F.J., and Hill C.S. Attenuation of the TGF-β-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-β-induced growth arrest. Oncogene 22 (2003) 3698-3711
-
(2003)
Oncogene
, vol.22
, pp. 3698-3711
-
-
Nicolas, F.J.1
Hill, C.S.2
-
26
-
-
26244439497
-
The endogenous ratio of Smad2 and Smad3 influences the cytostatic function of Smad3
-
Kim S.G., et al. The endogenous ratio of Smad2 and Smad3 influences the cytostatic function of Smad3. Mol. Biol. Cell 16 (2005) 4672-4683
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 4672-4683
-
-
Kim, S.G.1
-
27
-
-
41949103636
-
SnapShot: the TGF β pathway interactome
-
378.e1
-
Taylor I.W., and Wrana J.L. SnapShot: the TGF β pathway interactome. Cell 133 (2008) 378.e1
-
(2008)
Cell
, vol.133
-
-
Taylor, I.W.1
Wrana, J.L.2
-
28
-
-
41149127885
-
Theoretical and experimental approaches to understand morphogen gradients
-
Ibanes M., and Belmonte J.C. Theoretical and experimental approaches to understand morphogen gradients. Mol. Syst. Biol. 4 (2008) 176
-
(2008)
Mol. Syst. Biol.
, vol.4
, pp. 176
-
-
Ibanes, M.1
Belmonte, J.C.2
-
29
-
-
36749099486
-
Variability and robustness in biomolecular systems
-
Barkai N., and Shilo B.Z. Variability and robustness in biomolecular systems. Mol. Cell 28 (2007) 755-760
-
(2007)
Mol. Cell
, vol.28
, pp. 755-760
-
-
Barkai, N.1
Shilo, B.Z.2
-
30
-
-
0037136555
-
Robustness of the BMP morphogen gradient in Drosophila embryonic patterning
-
Eldar A., et al. Robustness of the BMP morphogen gradient in Drosophila embryonic patterning. Nature 419 (2002) 304-308
-
(2002)
Nature
, vol.419
, pp. 304-308
-
-
Eldar, A.1
-
31
-
-
19944369429
-
Formation of the BMP activity gradient in the Drosophila embryo
-
Mizutani C.M., et al. Formation of the BMP activity gradient in the Drosophila embryo. Dev. Cell 8 (2005) 915-924
-
(2005)
Dev. Cell
, vol.8
, pp. 915-924
-
-
Mizutani, C.M.1
-
32
-
-
17644394929
-
Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo
-
Shimmi O., et al. Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo. Cell 120 (2005) 873-886
-
(2005)
Cell
, vol.120
, pp. 873-886
-
-
Shimmi, O.1
-
33
-
-
15044338867
-
Spatial bistability of Dpp-receptor interactions during Drosophila dorsal-ventral patterning
-
Wang Y.C., and Ferguson E.L. Spatial bistability of Dpp-receptor interactions during Drosophila dorsal-ventral patterning. Nature 434 (2005) 229-234
-
(2005)
Nature
, vol.434
, pp. 229-234
-
-
Wang, Y.C.1
Ferguson, E.L.2
-
34
-
-
33746813251
-
Robust, bistable patterning of the dorsal surface of the Drosophila embryo
-
Umulis D.M., et al. Robust, bistable patterning of the dorsal surface of the Drosophila embryo. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 11613-11618
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 11613-11618
-
-
Umulis, D.M.1
-
35
-
-
0037598870
-
Distinct endocytic pathways regulate TGF-β receptor signalling and turnover
-
Di Guglielmo G.M., et al. Distinct endocytic pathways regulate TGF-β receptor signalling and turnover. Nat. Cell Biol. 5 (2003) 410-421
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 410-421
-
-
Di Guglielmo, G.M.1
-
36
-
-
4344606636
-
Ligand-dependent and -independent transforming growth factor-β receptor recycling regulated by clathrin-mediated endocytosis and Rab11
-
Mitchell H., et al. Ligand-dependent and -independent transforming growth factor-β receptor recycling regulated by clathrin-mediated endocytosis and Rab11. Mol. Biol. Cell 15 (2004) 4166-4178
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 4166-4178
-
-
Mitchell, H.1
-
37
-
-
33645754505
-
Signal processing in the TGF-β superfamily ligand-receptor network
-
Vilar J.M., et al. Signal processing in the TGF-β superfamily ligand-receptor network. PLoS Comput. Biol. 2 (2006) e3
-
(2006)
PLoS Comput. Biol.
, vol.2
-
-
Vilar, J.M.1
-
38
-
-
41549094989
-
Constraint-based modeling and kinetic analysis of the Smad dependent TGF-β signaling pathway
-
Zi Z., and Klipp E. Constraint-based modeling and kinetic analysis of the Smad dependent TGF-β signaling pathway. PLoS ONE 2 (2007) e936
-
(2007)
PLoS ONE
, vol.2
-
-
Zi, Z.1
Klipp, E.2
-
39
-
-
27644583784
-
Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor β-dependent nuclear accumulation of Smads
-
Schmierer B., and Hill C.S. Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor β-dependent nuclear accumulation of Smads. Mol. Cell. Biol. 25 (2005) 9845-9858
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 9845-9858
-
-
Schmierer, B.1
Hill, C.S.2
-
40
-
-
33645891645
-
Postsynaptic mad signaling at the Drosophila neuromuscular junction
-
Dudu V., et al. Postsynaptic mad signaling at the Drosophila neuromuscular junction. Curr. Biol. 16 (2006) 625-635
-
(2006)
Curr. Biol.
, vol.16
, pp. 625-635
-
-
Dudu, V.1
-
41
-
-
4944223639
-
Analysis of Smad nucleocytoplasmic shuttling in living cells
-
Nicolas F.J., et al. Analysis of Smad nucleocytoplasmic shuttling in living cells. J. Cell Sci. 117 (2004) 4113-4125
-
(2004)
J. Cell Sci.
, vol.117
, pp. 4113-4125
-
-
Nicolas, F.J.1
-
42
-
-
33645969033
-
Dissecting the contribution of diffusion and interactions to the mobility of nuclear proteins
-
Beaudouin J., et al. Dissecting the contribution of diffusion and interactions to the mobility of nuclear proteins. Biophys. J. 90 (2006) 1878-1894
-
(2006)
Biophys. J.
, vol.90
, pp. 1878-1894
-
-
Beaudouin, J.1
-
43
-
-
33750845118
-
Systems theory of Smad signalling
-
Clarke D.C., et al. Systems theory of Smad signalling. Syst. Biol. (Stevenage) 153 (2006) 412-424
-
(2006)
Syst. Biol. (Stevenage)
, vol.153
, pp. 412-424
-
-
Clarke, D.C.1
-
44
-
-
0036333146
-
A changing morphogen gradient is interpreted by continuous transduction flow
-
Bourillot P.Y., et al. A changing morphogen gradient is interpreted by continuous transduction flow. Development 129 (2002) 2167-2180
-
(2002)
Development
, vol.129
, pp. 2167-2180
-
-
Bourillot, P.Y.1
-
45
-
-
0032524323
-
The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors
-
Dyson S., and Gurdon J.B. The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors. Cell 93 (1998) 557-568
-
(1998)
Cell
, vol.93
, pp. 557-568
-
-
Dyson, S.1
Gurdon, J.B.2
-
46
-
-
33845424529
-
A rate equation approach to elucidate the kinetics and robustness of the TGF-β pathway
-
Melke P., et al. A rate equation approach to elucidate the kinetics and robustness of the TGF-β pathway. Biophys. J. 91 (2006) 4368-4380
-
(2006)
Biophys. J.
, vol.91
, pp. 4368-4380
-
-
Melke, P.1
-
47
-
-
44349125602
-
Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system
-
Schmierer B., et al. Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 6608-6613
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 6608-6613
-
-
Schmierer, B.1
-
48
-
-
34548842261
-
Msk is required for nuclear import of TGF-β/BMP-activated Smads
-
Xu L., et al. Msk is required for nuclear import of TGF-β/BMP-activated Smads. J. Cell Biol. 178 (2007) 981-994
-
(2007)
J. Cell Biol.
, vol.178
, pp. 981-994
-
-
Xu, L.1
-
49
-
-
38348998668
-
Nuclear accumulation of Smad complexes occurs only after the midblastula transition in Xenopus
-
Saka Y., et al. Nuclear accumulation of Smad complexes occurs only after the midblastula transition in Xenopus. Development 134 (2007) 4209-4218
-
(2007)
Development
, vol.134
, pp. 4209-4218
-
-
Saka, Y.1
-
50
-
-
0036894034
-
Morphogen gradients, positional information, and Xenopus: interplay of theory and experiment
-
Green J. Morphogen gradients, positional information, and Xenopus: interplay of theory and experiment. Dev. Dyn. 225 (2002) 392-408
-
(2002)
Dev. Dyn.
, vol.225
, pp. 392-408
-
-
Green, J.1
-
51
-
-
0034798578
-
Modeling the effects of transforming growth factor-β on extracellular matrix alignment in dermal wound repair
-
Dallon J.C., et al. Modeling the effects of transforming growth factor-β on extracellular matrix alignment in dermal wound repair. Wound Repair Regen. 9 (2001) 278-286
-
(2001)
Wound Repair Regen.
, vol.9
, pp. 278-286
-
-
Dallon, J.C.1
-
52
-
-
33646249607
-
A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies
-
Ribba B., et al. A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies. Theor. Biol. Med. Model. 3 (2006) 7
-
(2006)
Theor. Biol. Med. Model.
, vol.3
, pp. 7
-
-
Ribba, B.1
-
53
-
-
32244437156
-
Shaping BMP morphogen gradients in the Drosophila embryo and pupal wing
-
O'Connor M.B., et al. Shaping BMP morphogen gradients in the Drosophila embryo and pupal wing. Development 133 (2006) 183-193
-
(2006)
Development
, vol.133
, pp. 183-193
-
-
O'Connor, M.B.1
-
54
-
-
23044466047
-
Specificity and versatility in TGF-β signaling through Smads
-
Feng X.H., and Derynck R. Specificity and versatility in TGF-β signaling through Smads. Annu. Rev. Cell Dev. Biol. 21 (2005) 659-693
-
(2005)
Annu. Rev. Cell Dev. Biol.
, vol.21
, pp. 659-693
-
-
Feng, X.H.1
Derynck, R.2
-
55
-
-
20444430827
-
Nuclear targeting of transforming growth factor-β-activated Smad complexes
-
Chen H.B., et al. Nuclear targeting of transforming growth factor-β-activated Smad complexes. J. Biol. Chem. 280 (2005) 21329-21336
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 21329-21336
-
-
Chen, H.B.1
-
56
-
-
0034253480
-
The nuclear import function of Smad2 is masked by SARA and unmasked by TGFβ-dependent phosphorylation
-
Xu L., et al. The nuclear import function of Smad2 is masked by SARA and unmasked by TGFβ-dependent phosphorylation. Nat. Cell Biol. 2 (2000) 559-562
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 559-562
-
-
Xu, L.1
-
57
-
-
32044436541
-
The mechanism of nuclear export of Smad3 involves exportin 4 and Ran
-
Kurisaki A., et al. The mechanism of nuclear export of Smad3 involves exportin 4 and Ran. Mol. Cell. Biol. 26 (2006) 1318-1332
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 1318-1332
-
-
Kurisaki, A.1
-
58
-
-
33244485265
-
The interpretation of morphogen gradients
-
Ashe H.L., and Briscoe J. The interpretation of morphogen gradients. Development 133 (2006) 385-394
-
(2006)
Development
, vol.133
, pp. 385-394
-
-
Ashe, H.L.1
Briscoe, J.2
-
59
-
-
34548049239
-
The Decapentaplegic morphogen gradient: from pattern formation to growth regulation
-
Affolter M., and Basler K. The Decapentaplegic morphogen gradient: from pattern formation to growth regulation. Nat. Rev. Genet. 8 (2007) 663-674
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 663-674
-
-
Affolter, M.1
Basler, K.2
-
60
-
-
0035480050
-
TGF-β signalling pathways in early Xenopus development
-
Hill C.S. TGF-β signalling pathways in early Xenopus development. Curr. Opin. Genet. Dev. 11 (2001) 533-540
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 533-540
-
-
Hill, C.S.1
-
61
-
-
0026496172
-
TGF β signals through a heteromeric protein kinase receptor complex
-
Wrana J.L., et al. TGF β signals through a heteromeric protein kinase receptor complex. Cell 71 (1992) 1003-1014
-
(1992)
Cell
, vol.71
, pp. 1003-1014
-
-
Wrana, J.L.1
-
62
-
-
0028170226
-
Mechanism of activation of the TGF-β receptor
-
Wrana J.L., et al. Mechanism of activation of the TGF-β receptor. Nature 370 (1994) 341-347
-
(1994)
Nature
, vol.370
, pp. 341-347
-
-
Wrana, J.L.1
-
63
-
-
0030613262
-
Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-β signaling
-
Souchelnytskyi S., et al. Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-β signaling. J. Biol. Chem. 272 (1997) 28107-28115
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28107-28115
-
-
Souchelnytskyi, S.1
-
64
-
-
0030886204
-
Transforming growth factor β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells
-
Liu X., et al. Transforming growth factor β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 10669-10674
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 10669-10674
-
-
Liu, X.1
-
65
-
-
0029834067
-
Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways
-
Lagna G., et al. Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways. Nature 383 (1996) 832-836
-
(1996)
Nature
, vol.383
, pp. 832-836
-
-
Lagna, G.1
-
66
-
-
4444250157
-
Structural basis of heteromeric smad protein assembly in TGF-β signaling
-
Chacko B.M., et al. Structural basis of heteromeric smad protein assembly in TGF-β signaling. Mol. Cell 15 (2004) 813-823
-
(2004)
Mol. Cell
, vol.15
, pp. 813-823
-
-
Chacko, B.M.1
-
67
-
-
33745188200
-
Smad7 and protein phosphatase 1 α are critical determinants in the duration of TGF-β/ALK1 signaling in endothelial cells
-
Valdimarsdottir G., et al. Smad7 and protein phosphatase 1 α are critical determinants in the duration of TGF-β/ALK1 signaling in endothelial cells. BMC Cell Biol. 7 (2006) 16
-
(2006)
BMC Cell Biol.
, vol.7
, pp. 16
-
-
Valdimarsdottir, G.1
-
68
-
-
33847716712
-
Negative regulation of TGF-β receptor/Smad signal transduction
-
Itoh S., and Ten Dijke P. Negative regulation of TGF-β receptor/Smad signal transduction. Curr. Opin. Cell Biol. 19 (2007) 176-184
-
(2007)
Curr. Opin. Cell Biol.
, vol.19
, pp. 176-184
-
-
Itoh, S.1
Ten Dijke, P.2
-
69
-
-
0034460336
-
Transforming growth factor β-independent shuttling of Smad4 between the cytoplasm and nucleus
-
Pierreux C.E., et al. Transforming growth factor β-independent shuttling of Smad4 between the cytoplasm and nucleus. Mol. Cell. Biol. 20 (2000) 9041-9054
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 9041-9054
-
-
Pierreux, C.E.1
-
70
-
-
33845605130
-
Mathematical modeling as a tool for investigating cell cycle control networks
-
Sible J.C., and Tyson J.J. Mathematical modeling as a tool for investigating cell cycle control networks. Methods 41 (2007) 238-247
-
(2007)
Methods
, vol.41
, pp. 238-247
-
-
Sible, J.C.1
Tyson, J.J.2
-
71
-
-
34548049053
-
Mathematical modeling of intracellular signaling pathways
-
Klipp E., and Liebermeister W. Mathematical modeling of intracellular signaling pathways. BMC Neurosci. 7 Suppl 1 (2006) S10
-
(2006)
BMC Neurosci.
, vol.7
, Issue.SUPPL. 1
-
-
Klipp, E.1
Liebermeister, W.2
-
72
-
-
33747830489
-
Quantitative modeling in cell biology: what is it good for? Dev
-
Mogilner A., et al. Quantitative modeling in cell biology: what is it good for? Dev. Cell 11 (2006) 279-287
-
(2006)
Cell
, vol.11
, pp. 279-287
-
-
Mogilner, A.1
-
73
-
-
33747871080
-
Quantitative models of developmental pattern formation
-
Reeves G.T., et al. Quantitative models of developmental pattern formation. Dev. Cell 11 (2006) 289-300
-
(2006)
Dev. Cell
, vol.11
, pp. 289-300
-
-
Reeves, G.T.1
-
75
-
-
33646876973
-
Hematopoiesis controlled by distinct TIF1 γ and Smad4 branches of the TGF β pathway
-
He W., et al. Hematopoiesis controlled by distinct TIF1 γ and Smad4 branches of the TGF β pathway. Cell 125 (2006) 929-941
-
(2006)
Cell
, vol.125
, pp. 929-941
-
-
He, W.1
-
76
-
-
0025222517
-
The transforming growth factor-β family
-
Massague J. The transforming growth factor-β family. Annu. Rev. Cell Biol. 6 (1990) 597-641
-
(1990)
Annu. Rev. Cell Biol.
, vol.6
, pp. 597-641
-
-
Massague, J.1
-
77
-
-
0242684423
-
Transforming growth factor-β (TGF-β) binding to the extracellular domain of the type II TGF-β receptor: receptor capture on a biosensor surface using a new coiled-coil capture system demonstrates that avidity contributes significantly to high affinity binding
-
De Crescenzo G., et al. Transforming growth factor-β (TGF-β) binding to the extracellular domain of the type II TGF-β receptor: receptor capture on a biosensor surface using a new coiled-coil capture system demonstrates that avidity contributes significantly to high affinity binding. J. Mol. Biol. 328 (2003) 1173-1183
-
(2003)
J. Mol. Biol.
, vol.328
, pp. 1173-1183
-
-
De Crescenzo, G.1
-
78
-
-
0033768824
-
Identification and characterization of constitutively active Smad2 mutants: evaluation of formation of Smad complex and subcellular distribution
-
Funaba M., and Mathews L.S. Identification and characterization of constitutively active Smad2 mutants: evaluation of formation of Smad complex and subcellular distribution. Mol. Endocrinol. 14 (2000) 1583-1591
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 1583-1591
-
-
Funaba, M.1
Mathews, L.S.2
-
79
-
-
0034517389
-
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF β receptor for degradation
-
Kavsak P., et al. Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF β receptor for degradation. Mol. Cell 6 (2000) 1365-1375
-
(2000)
Mol. Cell
, vol.6
, pp. 1365-1375
-
-
Kavsak, P.1
-
80
-
-
38649088246
-
Cooperative assembly of TGF-β superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding
-
Groppe J., et al. Cooperative assembly of TGF-β superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding. Mol. Cell 29 (2008) 157-168
-
(2008)
Mol. Cell
, vol.29
, pp. 157-168
-
-
Groppe, J.1
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