-
1
-
-
0034604110
-
Role of transforming growth factor β in human disease
-
DOI 10.1056/NEJM200005043421807
-
G.C. Blobe, W.P. Schiemann, and H.F. Lodish Role of transforming growth factor beta in human disease N Engl J Med 342 2000 1350 1358 (Pubitemid 30408720)
-
(2000)
New England Journal of Medicine
, vol.342
, Issue.18
, pp. 1350-1358
-
-
Blobe, G.C.1
Schiemann, W.P.2
Lodish, H.F.3
-
2
-
-
0034644472
-
TGFbeta signalling in growth control, cancer, and heritable disorders
-
J.B. Massague, S.W. Blain, and R.S. Lo TGFbeta signalling in growth control, cancer, and heritable disorders Cell 103 2000 295 309
-
(2000)
Cell
, vol.103
, pp. 295-309
-
-
Massague, J.B.1
Blain, S.W.2
Lo, R.S.3
-
3
-
-
23044466047
-
Specificity and versatility in TGF-β signaling through smads
-
DOI 10.1146/annurev.cellbio.21.022404.142018
-
X.H. Feng, and R. Derynck Specificity and versatility in TGF-beta signalling through Smads Annu Rev Cell Dev Biol 21 2005 659 693 (Pubitemid 41740650)
-
(2005)
Annual Review of Cell and Developmental Biology
, vol.21
, pp. 659-693
-
-
Feng, X.-H.1
Derynck, R.2
-
4
-
-
36448936383
-
TGFβ-SMAD signal transduction: Molecular specificity and functional flexibility
-
DOI 10.1038/nrm2297, PII NRM2297
-
B. Schmierer, and C.S. Hill TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility Nat Rev Mol Cell Biol 8 2007 970 982 (Pubitemid 350174642)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.12
, pp. 970-982
-
-
Schmierer, B.1
Hill, C.S.2
-
5
-
-
58149213801
-
Non-Smad pathways in TGF-beta signalling
-
Y.E. Zhang Non-Smad pathways in TGF-beta signalling Cell Res 19 2009 128 139
-
(2009)
Cell Res
, vol.19
, pp. 128-139
-
-
Zhang, Y.E.1
-
7
-
-
34548145815
-
Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition
-
DOI 10.1074/jbc.M700194200
-
M. Zeisberg, C. Yang, M. Martino, M.B. Duncan, F. Rieder, and H. Tanjore Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition J Biol Chem 282 2007 23337 23347 (Pubitemid 47311952)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.32
, pp. 23337-23347
-
-
Zeisberg, M.1
Yang, C.2
Martino, M.3
Duncan, M.B.4
Rieder, F.5
Tanjore, H.6
Kalluri, R.7
-
8
-
-
48549084059
-
Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage
-
S. Dooley, J. Hamzavi, L. Ciuclan, P. Godoy, I. Ilkavets, and S. Ehnert Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage Gastroenterology 135 2008 642 659
-
(2008)
Gastroenterology
, vol.135
, pp. 642-659
-
-
Dooley, S.1
Hamzavi, J.2
Ciuclan, L.3
Godoy, P.4
Ilkavets, I.5
Ehnert, S.6
-
9
-
-
77950597707
-
Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice
-
K. Taura, K. Miura, K. Iwaisako, C.H. Osterreicher, Y. Kodama, and M. Penz-Osterreicher Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice Hepatology 51 2010 1027 1036
-
(2010)
Hepatology
, vol.51
, pp. 1027-1036
-
-
Taura, K.1
Miura, K.2
Iwaisako, K.3
Osterreicher, C.H.4
Kodama, Y.5
Penz-Osterreicher, M.6
-
10
-
-
36348932917
-
Profibrogenic transforming growth factor-β/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes
-
DOI 10.1002/hep.21806
-
H.L. Weng, L. Ciuclan, Y. Liu, J. Hamzavi, P. Godoy, and H. Gaitantzi Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signalling via connective tissue growth factor expression in hepatocytes Hepatology 46 2007 1257 1270 (Pubitemid 350144790)
-
(2007)
Hepatology
, vol.46
, Issue.4
, pp. 1257-1270
-
-
Weng, H.-L.1
Ciuclan, L.2
Liu, Y.3
Hamzavi, J.4
Godoy, P.5
Gaitantzi, H.6
Kanzler, S.7
Heuchel, R.8
Ueberham, U.9
Gebhardt, R.10
Breitkopf, K.11
Dooley, S.12
-
11
-
-
0031845816
-
Connective tissue growth factor mRNA expression is upregulated in bleomycin-induced lung fibrosis
-
J.A. Lasky, L.A. Ortiz, B. Tonthat, G.W. Hoyle, M. Corti, and G. Athas Connective tissue growth factor mRNA expression is upregulated in bleomycin-induced lung fibrosis Am J Physiol 275 1998 L365 L371
-
(1998)
Am J Physiol
, vol.275
-
-
Lasky, J.A.1
Ortiz, L.A.2
Tonthat, B.3
Hoyle, G.W.4
Corti, M.5
Athas, G.6
-
12
-
-
0031225015
-
Connective tissue growth factor: A mediator of TGf-β action on fibroblasts
-
DOI 10.1016/S1359-6101(97)00010-5, PII S1359610197000105
-
G.R. Grotendorst Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts Cytokine Growth Factor Rev 8 1997 171 179 (Pubitemid 28077925)
-
(1997)
Cytokine and Growth Factor Reviews
, vol.8
, Issue.3
, pp. 171-179
-
-
Grotendorst, G.R.1
-
13
-
-
68949101788
-
Connective tissue growth factor is a Smad2 regulated amplifier of transforming growth factor beta actions in hepatocytes - But without modulating bone morphogenetic protein 7 signalling
-
O.A. Gressner, B. Lahme, M. Siluschek, K. Rehbein, R. Weiskirchen, and A.M. Gressner Connective tissue growth factor is a Smad2 regulated amplifier of transforming growth factor beta actions in hepatocytes - but without modulating bone morphogenetic protein 7 signalling Hepatology 49 2009 2021 2030
-
(2009)
Hepatology
, vol.49
, pp. 2021-2030
-
-
Gressner, O.A.1
Lahme, B.2
Siluschek, M.3
Rehbein, K.4
Weiskirchen, R.5
Gressner, A.M.6
-
14
-
-
58149269185
-
Endocytic regulation of TGF-beta signalling
-
Y.G. Chen Endocytic regulation of TGF-beta signalling Cell Res 19 2009 58 70
-
(2009)
Cell Res
, vol.19
, pp. 58-70
-
-
Chen, Y.G.1
-
15
-
-
0037598870
-
Distinct endocytic pathways regulate TGF-β receptor signalling and turnover
-
DOI 10.1038/ncb975
-
G.M. Di Guglielmo, C. Le Roy, A.F. Goodfellow, and J.L. Wrana Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover Nat Cell Biol 5 2003 410 421 (Pubitemid 36592263)
-
(2003)
Nature Cell Biology
, vol.5
, Issue.5
, pp. 410-421
-
-
Di Guglielmo, G.M.1
Le Roy, C.2
Goodfellow, A.F.3
Wrana, J.L.4
-
16
-
-
0036201871
-
The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-β/Smad signalling
-
DOI 10.1046/j.1365-2443.2002.00519.x
-
F. Itoh, N. Divecha, L. Brocks, L. Oomen, H. Janssen, and J. Calafat The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-beta/Smad signalling Genes Cells 7 2002 321 331 (Pubitemid 34257665)
-
(2002)
Genes to Cells
, vol.7
, Issue.3
, pp. 321-331
-
-
Itoh, F.1
Divecha, N.2
Brocks, L.3
Oomen, L.4
Janssen, H.5
Calafat, J.6
Itoh, S.7
Dijke, P.T.8
-
17
-
-
0032428684
-
SARA, a FYVE domain protein that recruits Smad2 to the TGFβ receptor
-
DOI 10.1016/S0092-8674(00)81701-8
-
T. Tsukazaki, T.A. Chiang, A.F. Davison, L. Attisano, and J.L. Wrana SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor Cell 95 1998 779 791 (Pubitemid 29014458)
-
(1998)
Cell
, vol.95
, Issue.6
, pp. 779-791
-
-
Tsukazaki, T.1
Chiang, T.A.2
Davison, A.F.3
Attisano, L.4
Wrana, J.L.5
-
18
-
-
0035918274
-
Smurf1 interacts with transforming growth factor-beta type i receptor through Smad7 and induces receptor degradation
-
T. Ebisawa, M. Fukuchi, G. Murakami, T. Chiba, K. Tanaka, and T. Imamura Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation J Biol Chem 276 2001 12477 12480
-
(2001)
J Biol Chem
, vol.276
, pp. 12477-12480
-
-
Ebisawa, T.1
Fukuchi, M.2
Murakami, G.3
Chiba, T.4
Tanaka, K.5
Imamura, T.6
-
19
-
-
0034517389
-
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGFβ receptor for degradation
-
DOI 10.1016/S1097-2765(00)00134-9
-
P. Kavsak, R.K. Rasmussen, C.G. Causing, S. Bonni, H. Zhu, and G.H. Thomsen Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation Mol Cell 6 2000 1365 1375 (Pubitemid 32045929)
-
(2000)
Molecular Cell
, vol.6
, Issue.6
, pp. 1365-1375
-
-
Kavsak, P.1
Rasmussen, R.K.2
Causing, C.G.3
Bonni, S.4
Zhu, H.5
Thomsen, G.H.6
Wrana, J.L.7
-
20
-
-
0036272313
-
Internalization-dependent and -independent requirements for transforming growth factor β receptor signaling via the Smad pathway
-
DOI 10.1128/MCB.22.13.4750-4759.2002
-
S.G. Penheiter, H. Mitchell, N. Garamszegi, M. Edens, J.J. Dore Jr., and E.B. Leof Internalization-dependent and -independent requirements for transforming growth factor beta receptor signalling via the Smad pathway Mol Cell Biol 22 2002 4750 4759 (Pubitemid 34620410)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.13
, pp. 4750-4759
-
-
Penheiter, S.G.1
Mitchell, H.2
Garamszegi, N.3
Edens, M.4
Dore Jr., J.J.E.5
Leof, E.B.6
-
21
-
-
0037144841
-
TGF beta receptor internalization into EEA1-enriched early endosomes: Role in signalling to Smad2
-
S. Hayes, A. Chawla, and S. Corvera TGF beta receptor internalization into EEA1-enriched early endosomes: role in signalling to Smad2 J Cell Biol 158 2002 1239 1249
-
(2002)
J Cell Biol
, vol.158
, pp. 1239-1249
-
-
Hayes, S.1
Chawla, A.2
Corvera, S.3
-
22
-
-
14844307044
-
The role of internalization in transforming growth factor β1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signaling in human mesangial cells
-
DOI 10.1074/jbc.M407939200
-
C.E. Runyan, H.W. Schnaper, and A.C. Poncelet The role of internalization in transforming growth factor beta1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signalling in human mesangial cells J Biol Chem 280 2005 8300 8308 (Pubitemid 40349732)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.9
, pp. 8300-8308
-
-
Runyan, C.E.1
Schnaper, H.W.2
Poncelet, A.-C.3
-
23
-
-
69049085270
-
Inhibitors of clathrin-dependent endocytosis enhance TGFbeta signalling and responses
-
C.L. Chen, W.H. Hou, I.H. Liu, G. Hsiao, S.S. Huang, and J.S. Huang Inhibitors of clathrin-dependent endocytosis enhance TGFbeta signalling and responses J Cell Sci 122 2009 1863 1871
-
(2009)
J Cell Sci
, vol.122
, pp. 1863-1871
-
-
Chen, C.L.1
Hou, W.H.2
Liu, I.H.3
Hsiao, G.4
Huang, S.S.5
Huang, J.S.6
-
24
-
-
0031806620
-
Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathways
-
B.P. Ceresa, A.W. Kao, S.R. Santeler, and J.E. Pessin Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathways Mol Cell Biol 18 1998 3862 3870 (Pubitemid 28287909)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.7
, pp. 3862-3870
-
-
Ceresa, B.P.1
Kao, A.W.2
Santeler, S.R.3
Pessin, J.E.4
-
25
-
-
77449155377
-
Overexpression of caveolin-1 in lymphoblastoid TK6 cells enhances proliferation after irradiation with clinically relevant doses
-
D. Barzan, P. Maier, W.J. Zeller, F. Wenz, and C. Herskind Overexpression of caveolin-1 in lymphoblastoid TK6 cells enhances proliferation after irradiation with clinically relevant doses Strahlenther Onkol 186 2010 99 106
-
(2010)
Strahlenther Onkol
, vol.186
, pp. 99-106
-
-
Barzan, D.1
Maier, P.2
Zeller, W.J.3
Wenz, F.4
Herskind, C.5
-
26
-
-
41649115450
-
+ hematopoietic progenitor cells
-
DOI 10.1667/RR1067.1
-
P. Maier, C. Herskind, K. Fleckenstein, I. Spier, S. Laufs, and W.J. Zeller MDR1 gene transfer using a lentiviral SIN vector confers radioprotection to human CD34+ hematopoietic progenitor cells Radiat Res 169 2008 301 310 (Pubitemid 351521765)
-
(2008)
Radiation Research
, vol.169
, Issue.3
, pp. 301-310
-
-
Maier, P.1
Herskind, C.2
Fleckenstein, K.3
Spier, I.4
Laufs, S.5
Zeller, W.J.6
Fruehauf, S.7
Wenz, F.8
-
27
-
-
33750795440
-
Primary mouse hepatocytes for systems biology approaches: A standardized in vitro system for modelling of signal transduction pathways
-
DOI 10.1049/ip-syb:20050067
-
U. Klingmuller, A. Bauer, S. Bohl, P.J. Nickel, K. Breitkopf, and S. Dooley Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways Syst Biol (Stevenage) 153 2006 433 447 (Pubitemid 44712259)
-
(2006)
IEE Proceedings: Systems Biology
, vol.153
, Issue.6
, pp. 433-447
-
-
Klingmuller, U.1
Bauer, A.2
Bohl, S.3
Nickel, P.J.4
Breitkopf, K.5
Dooley, S.6
Zellmer, S.7
Kern, C.8
Merfort, I.9
Sparna, T.10
Donauer, J.11
Walz, G.12
Geyer, M.13
Kreutz, C.14
Hermes, M.15
Gotschel, F.16
Hecht, A.17
Walter, D.18
Egger, L.19
Neubert, K.20
Borner, C.21
Brulport, M.22
Schormann, W.23
Sauer, C.24
Baumann, F.25
Preiss, R.26
MacNelly, S.27
Godoy, P.28
Wiercinska, E.29
Ciuclan, L.30
Edelmann, J.31
Zeilinger, K.32
Heinrich, M.33
Zanger, U.M.34
Gebhardt, R.35
Maiwald, T.36
Heinrich, R.37
Timmer, J.38
Von Weizsacker, F.39
Hengstler, J.G.40
more..
-
28
-
-
67650999336
-
Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor beta-induced apoptosis
-
P. Godoy, J.G. Hengstler, I. Ilkavets, C. Meyer, A. Bachmann, and A. Muller Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor beta-induced apoptosis Hepatology 49 2009 2031 2043
-
(2009)
Hepatology
, vol.49
, pp. 2031-2043
-
-
Godoy, P.1
Hengstler, J.G.2
Ilkavets, I.3
Meyer, C.4
Bachmann, A.5
Muller, A.6
-
29
-
-
40749126837
-
Integration of transforming growth factor beta and RAS signalling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration
-
H. Hu, M. Milstein, J.M. Bliss, M. Thai, G. Malhotra, and L.C. Huynh Integration of transforming growth factor beta and RAS signalling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration Mol Cell Biol 28 2008 1573 1583
-
(2008)
Mol Cell Biol
, vol.28
, pp. 1573-1583
-
-
Hu, H.1
Milstein, M.2
Bliss, J.M.3
Thai, M.4
Malhotra, G.5
Huynh, L.C.6
-
30
-
-
48549088895
-
Clathrin-mediated internalization is essential for sustained EGFR signalling but dispensable for degradation
-
S. Sigismund, E. Argenzio, D. Tosoni, E. Cavallaro, S. Polo, and P.P. Di Fiore Clathrin-mediated internalization is essential for sustained EGFR signalling but dispensable for degradation Dev Cell 15 2008 209 219
-
(2008)
Dev Cell
, vol.15
, pp. 209-219
-
-
Sigismund, S.1
Argenzio, E.2
Tosoni, D.3
Cavallaro, E.4
Polo, S.5
Di Fiore, P.P.6
-
31
-
-
0032865109
-
Epidermal growth factor pathway substrate 15, Eps15
-
DOI 10.1016/S1357-2725(99)00042-4, PII S1357272599000424
-
A.E. Salcini, H. Chen, G. Iannolo, P. De Camilli, and P.P. Di Fiore Epidermal growth factor pathway substrate 15, Eps15 Int J Biochem Cell Biol 31 1999 805 809 (Pubitemid 29354077)
-
(1999)
International Journal of Biochemistry and Cell Biology
, vol.31
, Issue.8
, pp. 805-809
-
-
Salcini, A.E.1
Chen, H.2
Iannolo, G.3
De Camilli, P.4
Di Fiore, P.P.5
-
32
-
-
0033052332
-
Inhibition of clathrin-coated pit assembly by an Eps15 mutant
-
A. Benmerah, M. Bayrou, N. Cerf-Bensussan, and A. Dautry-Varsat Inhibition of clathrin-coated pit assembly by an Eps15 mutant J Cell Sci 112 1999 1303 1311 (Pubitemid 29243453)
-
(1999)
Journal of Cell Science
, vol.112
, Issue.9
, pp. 1303-1311
-
-
Benmerah, A.1
Bayrou, M.2
Cerf-Bensussan, N.3
Dautry-Varsat, A.4
-
33
-
-
0032498799
-
Ap-2/Eps15 interaction is required for receptor-mediated endocytosis
-
DOI 10.1083/jcb.140.5.1055
-
A. Benmerah, C. Lamaze, B. Begue, S.L. Schmid, A. Dautry-Varsat, and N. Cerf-Bensussan AP-2/Eps15 interaction is required for receptor-mediated endocytosis J Cell Biol 140 1998 1055 1062 (Pubitemid 28128866)
-
(1998)
Journal of Cell Biology
, vol.140
, Issue.5
, pp. 1055-1062
-
-
Benmerah, A.1
Lamaze, C.2
Begue, B.3
Schmid, S.L.4
Dautry-Varsat, A.5
Cerf-Bensussan, N.6
-
34
-
-
0031452290
-
Eps15 and eps15R are essential components of the endocytic pathway
-
R. Carbone, S. Fre, G. Iannolo, F. Belleudi, P. Mancini, and P.G. Pelicci Eps15 and eps15R are essential components of the endocytic pathway Cancer Res 57 1997 5498 5504 (Pubitemid 28006755)
-
(1997)
Cancer Research
, vol.57
, Issue.24
, pp. 5498-5504
-
-
Carbone, R.1
Fre, S.2
Iannolo, G.3
Belleudi, F.4
Mancini, P.5
Pelicci, P.G.6
Torrisi, M.R.7
Di Fiore, P.P.8
-
35
-
-
0027520440
-
Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation
-
DOI 10.1083/jcb.123.5.1107
-
L.H. Wang, K.G. Rothberg, and R.G. Anderson Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation J Cell Biol 123 1993 1107 1117 (Pubitemid 23352421)
-
(1993)
Journal of Cell Biology
, vol.123
, Issue.5
, pp. 1107-1117
-
-
Wang, L.-H.1
Rothberg, K.G.2
Anderson, R.G.W.3
-
36
-
-
0027534927
-
Clathrin and HA2 adaptors: Effects of potassium depletion, hypertonic medium, and cytosol acidification
-
S.H. Hansen, K. Sandvig, and B. van Deurs Clathrin and HA2 adaptors: effects of potassium depletion, hypertonic medium, and cytosol acidification J Cell Biol 121 1993 61 72 (Pubitemid 23097362)
-
(1993)
Journal of Cell Biology
, vol.121
, Issue.1
, pp. 61-72
-
-
Hansen, S.H.1
Sandvig, K.2
Van Deurs, B.3
-
37
-
-
0020626609
-
Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts
-
J.M. Larkin, M.S. Brown, J.L. Goldstein, and R.G. Anderson Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts Cell 33 1983 273 285 (Pubitemid 13096456)
-
(1983)
Cell
, vol.33
, Issue.1
, pp. 273-285
-
-
Larkin, J.M.1
Brown, M.S.2
Goldstein, J.L.3
Anderson, R.G.W.4
-
38
-
-
0024595608
-
Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation
-
DOI 10.1083/jcb.108.2.389
-
J.E. Heuser, and R.G. Anderson Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation J Cell Biol 108 1989 389 400 (Pubitemid 19065841)
-
(1989)
Journal of Cell Biology
, vol.108
, Issue.2
, pp. 389-400
-
-
Heuser, J.E.1
Anderson, R.G.W.2
-
39
-
-
36248952556
-
Cholesterol suppresses cellular TGF-β responsiveness: Implications in atherogenesis
-
DOI 10.1242/jcs.006916
-
C.L. Chen, I.H. Liu, S.J. Fliesler, X. Han, S.S. Huang, and J.S. Huang Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis J Cell Sci 120 2007 3509 3521 (Pubitemid 350120944)
-
(2007)
Journal of Cell Science
, vol.120
, Issue.20
, pp. 3509-3521
-
-
Chen, C.-L.1
Liu, I.-H.2
Fliesler, S.J.3
Han, X.4
Huang, S.S.5
Huang, J.S.6
-
40
-
-
2942614808
-
Hyaluronan regulates transforming growth factor-β1 receptor compartmentalization
-
DOI 10.1074/jbc.M403135200
-
T. Ito, J.D. Williams, D.J. Fraser, and A.O. Phillips Hyaluronan regulates transforming growth factor-beta1 receptor compartmentalization J Biol Chem 279 2004 25326 25332 (Pubitemid 38756787)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.24
, pp. 25326-25332
-
-
Ito, T.1
Williams, J.D.2
Fraser, D.J.3
Phillips, A.O.4
-
41
-
-
33744954407
-
Cellular heparan sulfate negatively modulates transforming growth factor-beta1 (TGF-beta1) responsiveness in epithelial cells
-
C.L. Chen, S.S. Huang, and J.S. Huang Cellular heparan sulfate negatively modulates transforming growth factor-beta1 (TGF-beta1) responsiveness in epithelial cells J Biol Chem 281 2006 11506 11514
-
(2006)
J Biol Chem
, vol.281
, pp. 11506-11514
-
-
Chen, C.L.1
Huang, S.S.2
Huang, J.S.3
-
42
-
-
0037119489
-
Transforming growth factor β activates Smad2 in the absence of receptor endocytosis
-
DOI 10.1074/jbc.M203495200
-
Z. Lu, J.T. Murray, W. Luo, H. Li, X. Wu, and H. Xu Transforming growth factor beta activates Smad2 in the absence of receptor endocytosis J Biol Chem 277 2002 29363 29368 (Pubitemid 41079219)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.33
, pp. 29363-29368
-
-
Lu, Z.1
Murray, J.T.2
Luo, W.3
Li, H.4
Wu, X.5
Xu, H.6
Backer, J.M.7
Chen, Y.-G.8
-
43
-
-
33749586993
-
Different routes of bone morphogenic protein (BMP) receptor endocytosis influence BMP signaling
-
DOI 10.1128/MCB.00022-06
-
A. Hartung, K. Bitton-Worms, M.M. Rechtman, V. Wenzel, J.H. Boergermann, and S. Hassel Different routes of bone morphogenic protein (BMP) receptor endocytosis influence BMP signalling Mol Cell Biol 26 2006 7791 7805 (Pubitemid 44547724)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.20
, pp. 7791-7805
-
-
Hartung, A.1
Bitton-Worms, K.2
Rechtman, M.M.3
Wenzel, V.4
Boergermann, J.H.5
Hassel, S.6
Henis, Y.I.7
Knaus, P.8
-
44
-
-
1842832338
-
Transforming growth factor-β receptors interact with AP2 by direct binding to β2 subunit
-
DOI 10.1091/mbc.02-07-0104
-
D. Yao, M. Ehrlich, Y.I. Henis, and E.B. Leof Transforming growth factor-beta receptors interact with AP2 by direct binding to beta2 subunit Mol Biol Cell 13 2002 4001 4012 (Pubitemid 35398566)
-
(2002)
Molecular Biology of the Cell
, vol.13
, Issue.11
, pp. 4001-4012
-
-
Yao, D.1
Ehrlich, M.2
Henis, Y.I.3
Leof, E.B.4
-
45
-
-
0036051343
-
Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta
-
J.G. Abreu, N.I. Ketpura, B. Reversade, and E.M. De Robertis Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta Nat Cell Biol 4 2002 599 604
-
(2002)
Nat Cell Biol
, vol.4
, pp. 599-604
-
-
Abreu, J.G.1
Ketpura, N.I.2
Reversade, B.3
De Robertis, E.M.4
-
46
-
-
33845906843
-
All in the CCN family: Essential matricellular signaling modulators emerge from the bunker
-
DOI 10.1242/jcs.03270
-
A. Leask, and D.J. Abraham All in the CCN family: essential matricellular signalling modulators emerge from the bunker J Cell Sci 119 2006 4803 4810 (Pubitemid 46017793)
-
(2006)
Journal of Cell Science
, vol.119
, Issue.23
, pp. 4803-4810
-
-
Leask, A.1
Abraham, D.J.2
-
47
-
-
33746265975
-
Inhibition of connective tissue growth factor by siRNA prevents liver fibrosis in rats
-
DOI 10.1002/jgm.894
-
G. Li, Q. Xie, Y. Shi, D. Li, M. Zhang, and S. Jiang Inhibition of connective tissue growth factor by siRNA prevents liver fibrosis in rats J Gene Med 8 2006 889 900 (Pubitemid 44097143)
-
(2006)
Journal of Gene Medicine
, vol.8
, Issue.7
, pp. 889-900
-
-
Li, G.1
Xie, Q.2
Shi, Y.3
Li, D.4
Zhang, M.5
Jiang, S.6
Zhou, H.7
Lu, H.8
Jin, Y.9
-
48
-
-
60249098260
-
Rac1 signalling regulates CTGF/CCN2 gene expression via TGFbeta/Smad signalling in chondrocytes
-
A. Woods, D. Pala, L. Kennedy, S. McLean, J.S. Rockel, and G. Wang Rac1 signalling regulates CTGF/CCN2 gene expression via TGFbeta/Smad signalling in chondrocytes Osteoarthritis Cartilage 17 2008 406 413
-
(2008)
Osteoarthritis Cartilage
, vol.17
, pp. 406-413
-
-
Woods, A.1
Pala, D.2
Kennedy, L.3
McLean, S.4
Rockel, J.S.5
Wang, G.6
-
49
-
-
41949091777
-
Molecular requirements for induction of CTGF expression by TGF-beta1 in primary osteoblasts
-
J.A. Arnott, X. Zhang, A. Sanjay, T.A. Owen, S.L. Smock, and S. Rehman Molecular requirements for induction of CTGF expression by TGF-beta1 in primary osteoblasts Bone 42 2008 871 885
-
(2008)
Bone
, vol.42
, pp. 871-885
-
-
Arnott, J.A.1
Zhang, X.2
Sanjay, A.3
Owen, T.A.4
Smock, S.L.5
Rehman, S.6
-
50
-
-
0034711307
-
Phosphatidylinositol 3-kinase function is required for transforming growth factor β-mediated epithelial to mesenchymal transition and cell migration
-
DOI 10.1074/jbc.M005912200
-
A.V. Bakin, A.K. Tomlinson, N.A. Bhowmick, H.L. Moses, and C.L. Arteaga Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration J Biol Chem 275 2000 36803 36810 (Pubitemid 32002090)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.47
, pp. 36803-36810
-
-
Bakin, A.V.1
Tomlinson, A.K.2
Bhowmick, N.A.3
Moses, H.L.4
Arteaga, C.L.5
-
51
-
-
34547587877
-
Cell size and invasion in TGF-β-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway
-
DOI 10.1083/jcb.200611146
-
S. Lamouille, and R. Derynck Cell size and invasion in TGF-beta-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway J Cell Biol 178 2007 437 451 (Pubitemid 47196152)
-
(2007)
Journal of Cell Biology
, vol.178
, Issue.3
, pp. 437-451
-
-
Lamouille, S.1
Derynck, R.2
-
52
-
-
15444372825
-
Type I transforming growth factor β receptor binds to and activates phosphatidylinositol 3-kinase
-
DOI 10.1074/jbc.M413223200
-
J.Y. Yi, I. Shin, and C.L. Arteaga Type I transforming growth factor beta receptor binds to and activates phosphatidylinositol 3-kinase J Biol Chem 280 2005 10870 10876 (Pubitemid 40395952)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.11
, pp. 10870-10876
-
-
Jae, Y.Y.1
Shin, I.2
Arteaga, C.L.3
-
53
-
-
33745050200
-
Activated type I TGFβ receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression
-
DOI 10.1038/sj.onc.1208964, PII 1208964
-
R.S. Muraoka-Cook, I. Shin, J.Y. Yi, E. Easterly, M.H. Barcellos-Hoff, and J.M. Yingling Activated type I TGFbeta receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression Oncogene 25 2006 3408 3423 (Pubitemid 43877044)
-
(2006)
Oncogene
, vol.25
, Issue.24
, pp. 3408-3423
-
-
Muraoka-Cook, R.S.1
Shin, I.2
Yi, J.Y.3
Easterly, E.4
Barcellos-Hoff, M.H.5
Yingling, J.M.6
Zent, R.7
Arteaga, C.L.8
-
54
-
-
0035794218
-
Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signalling through an interaction with the TGF-beta type i receptor
-
B. Razani, X.L. Zhang, M. Bitzer, G. von Gersdorff, E.P. Bottinger, and M.P. Lisanti Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signalling through an interaction with the TGF-beta type I receptor J Biol Chem 276 2001 6727 6738
-
(2001)
J Biol Chem
, vol.276
, pp. 6727-6738
-
-
Razani, B.1
Zhang, X.L.2
Bitzer, M.3
Von Gersdorff, G.4
Bottinger, E.P.5
Lisanti, M.P.6
-
55
-
-
64049102327
-
Specific activation of mitogen-activated protein kinase by transforming growth factor-beta receptors in lipid rafts is required for epithelial cell plasticity
-
W. Zuo, and Y.G. Chen Specific activation of mitogen-activated protein kinase by transforming growth factor-beta receptors in lipid rafts is required for epithelial cell plasticity Mol Biol Cell 20 2009 1020 1029
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1020-1029
-
-
Zuo, W.1
Chen, Y.G.2
-
56
-
-
77950481334
-
Impairment of TGF-{beta} signalling in caveolin-1 deficient hepatocytes: Role in liver regeneration
-
R. Mayoral, A.M. Valverde, C. Llorente Izquierdo, A. Gonzalez-Rodriguez, L. Bosca, and P. Martin-Sanz Impairment of TGF-{beta} signalling in caveolin-1 deficient hepatocytes: Role in liver regeneration J Biol Chem 285 2009 3633 3642
-
(2009)
J Biol Chem
, vol.285
, pp. 3633-3642
-
-
Mayoral, R.1
Valverde, A.M.2
Llorente Izquierdo, C.3
Gonzalez-Rodriguez, A.4
Bosca, L.5
Martin-Sanz, P.6
-
57
-
-
63049137530
-
Differential expression of caveolin-1 in hepatocellular carcinoma: Correlation with differentiation state, motility and invasion
-
M. Cokakli, E. Erdal, D. Nart, F. Yilmaz, O. Sagol, and M. Kilic Differential expression of caveolin-1 in hepatocellular carcinoma: correlation with differentiation state, motility and invasion BMC Cancer 9 2009 65
-
(2009)
BMC Cancer
, vol.9
, pp. 65
-
-
Cokakli, M.1
Erdal, E.2
Nart, D.3
Yilmaz, F.4
Sagol, O.5
Kilic, M.6
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