Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics

Molecular Systems Biology

Volumn 7, Issue , 2011, Pages

  Zi, Zhike ^a,b   Feng, Zipei ^b   Chapnick, Douglas A ^b   Dahl, Markus ^c   Deng, Difan ^a   Klipp, Edda ^d   Moustakas, Aristidis ^c,e   Liu, Xuedong ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF COLORADO   (United States)

^c UPPSALA UNIVERSITY   (Sweden)

^d HUMBOLDT UNIVERSITY   (Germany)

^e UPPSALA UNIVERSITY   (Sweden)

Author keywords

mathematical model; Smad; TGF ; ultrasensitivity

Indexed keywords

SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; PLASMINOGEN ACTIVATOR INHIBITOR 1; SMAD2 PROTEIN, HUMAN; SMAD7 PROTEIN, HUMAN;

ARTICLE; CELL FATE; CELL GROWTH; CELL PROLIFERATION; ENZYME ACTIVITY; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MATHEMATICAL MODEL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; BIOLOGICAL MODEL; CELL DIFFERENTIATION; CELL LINE; CYTOLOGY; GENETIC TRANSFECTION; GENETICS; KERATINOCYTE; MATHEMATICAL COMPUTING; METABOLISM; METHODOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SYSTEMS BIOLOGY;

MAMMALIA;

CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; GENE EXPRESSION; HUMANS; KERATINOCYTES; MATHEMATICAL COMPUTING; MODELS, BIOLOGICAL; PHOSPHORYLATION; PLASMINOGEN ACTIVATOR INHIBITOR 1; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD7 PROTEIN; SYSTEMS BIOLOGY; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 79957536131     PISSN: 17444292     EISSN: 17444292     Source Type: Journal    
DOI: 10.1038/msb.2011.22     Document Type: Article

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