AMPA receptors as drug targets in neurological disease - advantages, caveats, and future outlook

European Journal of Neuroscience

Volumn 35, Issue 12, 2012, Pages 1908-1916

  Chang, Philip K Y ^a   Verbich, David ^a   Mckinney, R Anne ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Alzheimer's disease; Ampakines; Dendritic spines; TARPs

Indexed keywords

2 [5 (4 DIMETHYLSULFAMOYLPHENYL) 6,7,8,9 TETRAHYDRO 8 METHYL 2 OXO 1H PYRROLO[3,2 H]ISOQUINOLIN 3 YLIMINOXY] 4 HYDROXYBUTYRIC ACID; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; AMPAKINE; BENZAMIDE DERIVATIVE; GLUTAMIC ACID; MIBAMPATOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PERAMPANEL; PLACEBO; POSTSYNAPTIC DENSITY PROTEIN 95; TALAMPANEL; UNCLASSIFIED DRUG; ZONAMPANEL;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; ATAXIA; BRAIN ISCHEMIA; COGNITIVE DEFECT; DIZZINESS; DROWSINESS; DRUG EFFICACY; DRUG POTENCY; DRUG TARGETING; DRUG TOLERABILITY; EPILEPSY; EXCITOTOXICITY; HUMAN; MEMORY DISORDER; MOTONEURON; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PSYCHOMOTOR DISORDER; SEIZURE; TRAUMATIC BRAIN INJURY; UNSPECIFIED SIDE EFFECT;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; EPILEPSY; EXCITATORY POSTSYNAPTIC POTENTIALS; HUMANS; MICE; MOLECULAR TARGETED THERAPY; NERVOUS SYSTEM DISEASES; NEUROTRANSMITTER AGENTS; RATS; RECEPTORS, AMPA;

EID: 84862658336     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2012.08165.x     Document Type: Article

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