Exposure of neurons to excitotoxic levels of glutamate induces cleavage of the RNA editing enzyme, adenosine deaminase acting on RNA 2, and loss of GLUR2 editing

Neuroscience

Volumn 189, Issue , 2011, Pages 305-315

  Mahajan, S S ^a,b   Thai, K H ^a   Chen, K ^a   Ziff, E ^b  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ADAR2; AMPA receptors; Amyotrophic lateral sclerosis (ALS); Calpain activation; Excitotoxicity; RNA editing

Indexed keywords

ADENOSINE DEAMINASE; AMPA RECEPTOR; ARGININE; CALCIUM ION; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; GLUTAMATE RECEPTOR 3; GLUTAMATE RECEPTOR 4; GLUTAMIC ACID; GLUTAMINE; RNA;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; EMBRYO; EXCITOTOXICITY; MOTONEURON; NERVE CELL; NERVE CELL CULTURE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; RAT; RNA EDITING;

ADENOSINE DEAMINASE; ANIMALS; CALCIUM; CELLS, CULTURED; GLUTAMIC ACID; NEURONS; NITRIC OXIDE SYNTHASE TYPE I; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; RNA CLEAVAGE; RNA EDITING;

EID: 79960918929     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.05.027     Document Type: Article

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