Behavioral and biological effects of chronic S18986, a positive AMPA receptor modulator, during aging

Experimental Neurology

Volumn 210, Issue 1, 2008, Pages 109-117

  Bloss, Erik B ^a   Hunter, Richard G ^a   Waters, Elizabeth M ^a   Munoz, Carmen ^b   Bernard, Katie ^b   McEwen, Bruce S ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b IRIS Institut de Recherches Internationales Servier   (France)

Author keywords

Aging; AMPAR modulation; Cognitive decline; Parkinson's disease; Spatial memory

Indexed keywords

2,3 DIHYDRO 3,4 CYCLOPENTANO 1,2,4 BENZOTHIADIAZINE 1,1 DIOXIDE; AMPA RECEPTOR; NEUROPROTECTIVE AGENT; UNCLASSIFIED DRUG;

AGING; ALLOSTERISM; ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITION; CONTROLLED STUDY; DENSITOMETRY; DRUG EFFECT; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MAZE TEST; MESENCEPHALON; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; POST HOC ANALYSIS; PRIORITY JOURNAL; RAT; SPATIAL MEMORY; SUBSTANTIA NIGRA;

ADMINISTRATION, ORAL; AGE FACTORS; AGING; ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD11B; BEHAVIOR, ANIMAL; BENZOTHIADIAZINES; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CHOLINE O-ACETYLTRANSFERASE; CORTICOSTERONE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLIAL FIBRILLARY ACIDIC PROTEIN; MALE; MAZE LEARNING; MOTOR ACTIVITY; NEURONS; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; TYROSINE 3-MONOOXYGENASE;

EID: 39149131762     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2007.10.007     Document Type: Article

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