메뉴 건너뛰기




Volumn 44, Issue 8, 2012, Pages 1276-1289

Histone modifications as a pathogenic mechanism of colorectal tumorigenesis

Author keywords

Colorectal cancer; Epigenetics; Histone acetylation; Methylation; Tumorigenesis

Indexed keywords

HISTONE; NONHISTONE PROTEIN;

EID: 84861478043     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2012.05.002     Document Type: Review
Times cited : (41)

References (175)
  • 1
    • 34447100055 scopus 로고    scopus 로고
    • Absence of MLL3 mutations in colorectal carcinomas of Korean patients [2]
    • DOI 10.1111/j.1600-0463.2007.apm-696.x
    • Ahn CH, Yoo NJ, Lee JW, Lee SH. Absence of MLL3 mutations in colorectal carcinomas of Korean patients. APMIS 2007;115:859-60. (Pubitemid 47030110)
    • (2007) APMIS , vol.115 , Issue.7 , pp. 859-860
    • Ahn, C.H.1    Yoo, N.J.2    Lee, J.W.3    Lee, S.H.4    Lee, S.H.5
  • 5
    • 34547896549 scopus 로고    scopus 로고
    • The MYST family of histone acetyltransferases and their intimate links to cancer
    • DOI 10.1038/sj.onc.1210608, PII 1210608
    • Avvakumov N, Cote J. The MYST family of histone acetyltransferases and their intimate links to cancer. Oncogene 2007;26:5395-407. (Pubitemid 47255922)
    • (2007) Oncogene , vol.26 , Issue.37 , pp. 5395-5407
    • Avvakumov, N.1    Cote, J.2
  • 7
    • 79952534189 scopus 로고    scopus 로고
    • Regulation of chromatin by histone modifications
    • Bannister AJ, Kouzarides T. Regulation of chromatin by histone modifications. Cell Research 2011;21:381-95.
    • (2011) Cell Research , vol.21 , pp. 381-395
    • Bannister, A.J.1    Kouzarides, T.2
  • 8
    • 0033837634 scopus 로고    scopus 로고
    • Regulation of gene expression by transcription factor acetylation
    • Bannister AJ, Miska EA. Regulation of gene expression by transcription factor acetylation. Cellular and Molecular Life Sciences 2000;57:1184-92. (Pubitemid 30663476)
    • (2000) Cellular and Molecular Life Sciences , vol.57 , Issue.8-9 , pp. 1184-1192
    • Bannister, A.J.1    Miska, E.A.2
  • 9
    • 33748451151 scopus 로고    scopus 로고
    • Anticancer activities of histone deacetylase inhibitors
    • DOI 10.1038/nrd2133, PII NRD2133
    • Bolden JE, Peart MJ, Johnstone RW. Anticancer activities of histone deacetylase inhibitors. Nature Reviews Drug Discovery 2006;5:769-84. (Pubitemid 44348499)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.9 , pp. 769-784
    • Bolden, J.E.1    Peart, M.J.2    Johnstone, R.W.3
  • 12
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and histone deacetylase inhibition in the re- expression of genes silenced in cancer
    • DOI 10.1038/5047
    • Cameron EE, Bachman KE, Myohanen S, Herman JG, Baylin SB. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nature Genetics 1999;21:103-7. (Pubitemid 29036293)
    • (1999) Nature Genetics , vol.21 , Issue.1 , pp. 103-107
    • Cameron, E.E.1    Bachman, K.E.2    Myohanen, S.3    Herman, J.G.4    Baylin, S.B.5
  • 13
    • 7044253370 scopus 로고    scopus 로고
    • No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer
    • Campbell IG, Choong D, Chenevix-Trench G. No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer. Breast Cancer Research 2004;6:R366-71.
    • (2004) Breast Cancer Research , vol.6
    • Campbell, I.G.1    Choong, D.2    Chenevix-Trench, G.3
  • 15
    • 67349190247 scopus 로고    scopus 로고
    • Linking DNA methylation and histone modification: Patterns and paradigms
    • Cedar H, Bergman Y. Linking DNA methylation and histone modification: patterns and paradigms. Nature Reviews Genetics 2009;10:295-304.
    • (2009) Nature Reviews Genetics , vol.10 , pp. 295-304
    • Cedar, H.1    Bergman, Y.2
  • 17
    • 0035979737 scopus 로고    scopus 로고
    • Duration of nuclear NF-κB action regulated by reversible acetylation
    • DOI 10.1126/science.1062374
    • Chen L, Fischle W, Verdin E, Greene WC. Duration of nuclear NF-κB action regulated by reversible acetylation. Science 2001;293:1653-7. (Pubitemid 32807844)
    • (2001) Science , vol.293 , Issue.5535 , pp. 1653-1657
    • Chen, L.-F.1    Fischle, W.2    Verdin, E.3    Greene, W.C.4
  • 18
    • 34249794601 scopus 로고    scopus 로고
    • WAF1 is related to acetylation of histone H3 in total chromatin in human colorectal cancer
    • Chen YX, Fang JY, Lu R, Qiu DK. Expression of p21(WAF1) is related to acetylation of histone H3 in total chromatin in human colorectal cancer. World Journal of Gastroenterology 2007;13:2209-13. (Pubitemid 46851158)
    • (2007) World Journal of Gastroenterology , vol.13 , Issue.15 , pp. 2209-2213
    • Chen, Y.-X.1    Fang, J.-Y.2    Lu, R.3    Qiu, D.-K.4
  • 20
    • 84862587893 scopus 로고    scopus 로고
    • An EZH2 polymorphism is associated with clinical outcome in metastatic colorectal cancer patients
    • Epub ahead of print
    • Crea F, Fornaro L, Paolicchi E, Masi G, Frumento P, Loupakis F, et al. An EZH2 polymorphism is associated with clinical outcome in metastatic colorectal cancer patients. Annals of Oncology 2011 (Epub ahead of print).
    • (2011) Annals of Oncology
    • Crea, F.1    Fornaro, L.2    Paolicchi, E.3    Masi, G.4    Frumento, P.5    Loupakis, F.6
  • 23
    • 1342331426 scopus 로고    scopus 로고
    • Clinicopathological significance of microsatellite instability and mutated RIZ in colorectal cancer
    • DOI 10.1093/annonc/mdh045
    • Emterling A, Wallin A, Arbman G, Sun XF. Clinicopathological significance of microsatellite instability and mutated RIZ in colorectal cancer. Annals of Oncology 2004;15:242-6. (Pubitemid 38262622)
    • (2004) Annals of Oncology , vol.15 , Issue.2 , pp. 242-246
    • Emterling, A.1    Wallin, A.2    Arbman, G.3    Sun, X.-F.4
  • 24
    • 80054123169 scopus 로고    scopus 로고
    • Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa
    • Enroth S, Rada-Iglesisas A, Andersson R, Wallerman O, Wanders A, Pahlman L, et al. Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa. BMC Cancer 2011;11:450.
    • (2011) BMC Cancer , vol.11 , pp. 450
    • Enroth, S.1    Rada-Iglesisas, A.2    Andersson, R.3    Wallerman, O.4    Wanders, A.5    Pahlman, L.6
  • 25
    • 36248983372 scopus 로고    scopus 로고
    • Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation
    • DOI 10.1074/jbc.M701847200
    • Evans PM, Zhang W, Chen X, Yang J, Bhakat KK, Liu C. Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation. Journal of Biological Chemistry 2007;282:33994-4002. (Pubitemid 350159428)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.47 , pp. 33994-34002
    • Evans, P.M.1    Zhang, W.2    Chen, X.3    Yang, J.4    Bhakat, K.K.5    Liu, C.6
  • 26
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990;61:759-67.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 27
    • 79251541733 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in the treatment of hematological malignancies and solid tumors
    • Federico M, Bagella L. Histone deacetylase inhibitors in the treatment of hematological malignancies and solid tumors. Journal of Biomedicine and Biotechnology 2011;2011:475641.
    • (2011) Journal of Biomedicine and Biotechnology , vol.2011 , pp. 475641
    • Federico, M.1    Bagella, L.2
  • 29
    • 70349958032 scopus 로고    scopus 로고
    • Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis
    • Fluge O, Gravdal K, Carlsen E, Vonen B, Kjellevold K, Refsum S, et al. Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis. British Journal of Cancer 2009;101:1282-9.
    • (2009) British Journal of Cancer , vol.101 , pp. 1282-1289
    • Fluge, O.1    Gravdal, K.2    Carlsen, E.3    Vonen, B.4    Kjellevold, K.5    Refsum, S.6
  • 30
    • 20144388146 scopus 로고    scopus 로고
    • Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
    • Fraga MF, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, Schotta G, et al. Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nature Genetics 2005;37:391-400.
    • (2005) Nature Genetics , vol.37 , pp. 391-400
    • Fraga, M.F.1    Ballestar, E.2    Villar-Garea, A.3    Boix-Chornet, M.4    Espada, J.5    Schotta, G.6
  • 31
    • 9444244427 scopus 로고    scopus 로고
    • Chromatin compaction by a polycomb group protein complex
    • DOI 10.1126/science.1100576
    • Francis NJ, Kingston RE, Woodcock CL. Chromatin compaction by a polycomb group protein complex. Science 2004;306:1574-7. (Pubitemid 39564957)
    • (2004) Science , vol.306 , Issue.5701 , pp. 1574-1577
    • Francis, N.J.1    Kingston, R.E.2    Woodcock, C.L.3
  • 35
    • 77957907885 scopus 로고    scopus 로고
    • Mutated KRAS results in overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas
    • Gaedcke J, Grade M, Jung K, Camps J, Jo P, Emons G, et al. Mutated KRAS results in overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas. Genes, Chromosomes and Cancer 2010;49:1024-34.
    • (2010) Genes, Chromosomes and Cancer , vol.49 , pp. 1024-1034
    • Gaedcke, J.1    Grade, M.2    Jung, K.3    Camps, J.4    Jo, P.5    Emons, G.6
  • 37
    • 0037135566 scopus 로고    scopus 로고
    • Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor
    • DOI 10.1074/jbc.M203423200
    • Gaughan L, Logan IR, Cook S, Neal DE, Robson CN. Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor. Journal of Biological Chemistry 2002;277:25904-13. (Pubitemid 34967070)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.29 , pp. 25904-25913
    • Gaughan, L.1    Logan, I.R.2    Cook, S.3    Neal, D.E.4    Robson, C.N.5
  • 40
    • 27944463521 scopus 로고    scopus 로고
    • Expression analysis of a subset of coregulators and three nuclear receptors in human colorectal carcinoma
    • Giannini R, Cavallini A. Expression analysis of a subset of coregulators and three nuclear receptors in human colorectal carcinoma. Anticancer Research 2005;25:4287-92. (Pubitemid 41665218)
    • (2005) Anticancer Research , vol.25 , Issue.6 B , pp. 4287-4292
    • Giannini, R.1    Cavallini, A.2
  • 41
    • 34547122494 scopus 로고    scopus 로고
    • HDAC inhibitors: Clinical update and mechanism-based potential
    • DOI 10.1016/j.bcp.2007.04.007, PII S0006295207002262
    • Glaser KB. HDAC inhibitors: clinical update and mechanism-based potential. Biochemical Pharmacology 2007;74:659-71. (Pubitemid 47096639)
    • (2007) Biochemical Pharmacology , vol.74 , Issue.5 , pp. 659-671
    • Glaser, K.B.1
  • 44
    • 0030798245 scopus 로고    scopus 로고
    • Histone acetylation in chromatin structure and transcription
    • DOI 10.1038/38664
    • Grunstein M. Histone acetylation in chromatin structure and transcription. Nature 1997;389:349-52. (Pubitemid 27415209)
    • (1997) Nature , vol.389 , Issue.6649 , pp. 349-352
    • Grunstein, M.1
  • 45
    • 0030797585 scopus 로고    scopus 로고
    • Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
    • DOI 10.1016/S0092-8674(00)80521-8
    • Gu W, Roeder RG. Activation of p53sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 1997;90:595-606. (Pubitemid 27357952)
    • (1997) Cell , vol.90 , Issue.4 , pp. 595-606
    • Gu, W.1    Roeder, R.G.2
  • 46
    • 0027485599 scopus 로고
    • Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: Implications for the possible role of dietary fibre in the prevention of large-bowel cancer
    • DOI 10.1002/ijc.2910550329
    • Hague A, Manning AM, Hanlon KA, Huschtscha LI, Hart D, Paraskeva C. Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer. International Journal of Cancer 1993;55:498-505. (Pubitemid 23300605)
    • (1993) International Journal of Cancer , vol.55 , Issue.3 , pp. 498-505
    • Hague, A.1    Manning, A.M.2    Hanlon, K.A.3    Huschtscha, L.I.4    Hart, D.5    Paraskeva, C.6
  • 48
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144:646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 50
    • 78649815150 scopus 로고    scopus 로고
    • Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers
    • Hayami S, Kelly JD, Cho HS, Yoshimatsu M, Unoki M, Tsunoda T, et al. Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers. International Journal of Cancer 2011;128:574-86.
    • (2011) International Journal of Cancer , vol.128 , pp. 574-586
    • Hayami, S.1    Kelly, J.D.2    Cho, H.S.3    Yoshimatsu, M.4    Unoki, M.5    Tsunoda, T.6
  • 51
    • 0028286187 scopus 로고
    • Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines
    • Heerdt BG, Houston MA, Augenlicht LH. Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Research 1994;54:3288-93.
    • (1994) Cancer Research , vol.54 , pp. 3288-3293
    • Heerdt, B.G.1    Houston, M.A.2    Augenlicht, L.H.3
  • 53
    • 0345357773 scopus 로고    scopus 로고
    • Gene Silencing in Cancer in Association with Promoter Hypermethylation
    • DOI 10.1056/NEJMra023075
    • Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. New England Journal of Medicine 2003;349:2042-54. (Pubitemid 37448928)
    • (2003) New England Journal of Medicine , vol.349 , Issue.21 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 54
    • 79958218684 scopus 로고    scopus 로고
    • Expression of histone deacetylase 1 and metastasis-associated protein 1 as prognostic factors in colon cancer
    • Higashijima J, Kurita N, Miyatani T, Yoshikawa K, Morimoto S, Nishioka M, et al. Expression of histone deacetylase 1 and metastasis-associated protein 1 as prognostic factors in colon cancer. Oncology Reports 2011;26:343-8.
    • (2011) Oncology Reports , vol.26 , pp. 343-348
    • Higashijima, J.1    Kurita, N.2    Miyatani, T.3    Yoshikawa, K.4    Morimoto, S.5    Nishioka, M.6
  • 57
    • 82055161827 scopus 로고    scopus 로고
    • Cancer chemoprevention by targeting the epigenome
    • Huang J, Plass C, Gerhauser C. Cancer chemoprevention by targeting the epigenome. Current Drug Targets 2011;12:1925-56.
    • (2011) Current Drug Targets , vol.12 , pp. 1925-1956
    • Huang, J.1    Plass, C.2    Gerhauser, C.3
  • 58
    • 0842320994 scopus 로고    scopus 로고
    • A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability
    • DOI 10.1073/pnas.0307276101
    • Ionov Y, Matsui S, Cowell JK. A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability. Proceedings of the National Academy of Sciences of the United States of America 2004;101:1273-8. (Pubitemid 38182679)
    • (2004) Proceedings of the National Academy of Sciences of the United States of America , vol.101 , Issue.5 , pp. 1273-1278
    • Ionov, Y.1    Matsui, S.-I.2    Cowell, J.K.3
  • 60
    • 2942612219 scopus 로고    scopus 로고
    • p300/CBP and cancer
    • DOI 10.1038/sj.onc.1207118
    • Iyer NG, Ozdag H, Caldas C. p300/CBP and cancer. Oncogene 2004;23:4225-31. (Pubitemid 38758588)
    • (2004) Oncogene , vol.23 , Issue.24 , pp. 4225-4231
    • Iyer, N.G.1    Ozdag, H.2    Caldas, C.3
  • 62
    • 0035266378 scopus 로고    scopus 로고
    • Adenovirus expressing RIZ1 in tumor suppressor gene therapy of microsatellite-unstable colorectal cancers
    • Jiang GL, Huang S. Adenovirus expressing RIZ1 in tumor suppressor gene therapy of microsatellite-unstable colorectal cancers. Cancer Research 2001;61:1796-8. (Pubitemid 32691986)
    • (2001) Cancer Research , vol.61 , Issue.5 , pp. 1796-1798
    • Jiang, G.-L.1    Huang, S.2
  • 63
    • 70349742486 scopus 로고    scopus 로고
    • DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer
    • Jin B, Yao B, Li JL, Fields CR, Delmas AL, Liu C, et al. DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer. Cancer Research 2009;69:7412-21.
    • (2009) Cancer Research , vol.69 , pp. 7412-7421
    • Jin, B.1    Yao, B.2    Li, J.L.3    Fields, C.R.4    Delmas, A.L.5    Liu, C.6
  • 64
    • 0041347519 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in cancer therapy: Is transcription the primary target?
    • DOI 10.1016/S1535-6108(03)00165-X
    • Johnstone RW, Licht JD. Histone deacetylase inhibitors in cancer therapy: is transcription the primary target. Cancer Cell 2003;4:13-8. (Pubitemid 36904157)
    • (2003) Cancer Cell , vol.4 , Issue.1 , pp. 13-18
    • Johnstone, R.W.1    Licht, J.D.2
  • 65
    • 33847065486 scopus 로고    scopus 로고
    • The Epigenomics of Cancer
    • DOI 10.1016/j.cell.2007.01.029, PII S0092867407001274
    • Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007;128:683-92. (Pubitemid 46273572)
    • (2007) Cell , vol.128 , Issue.4 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 67
  • 68
    • 35348914451 scopus 로고    scopus 로고
    • Association of the SUV39H1 histone methyltransferase with the DNA methyltransferase 1 at mRNA expression level in primary colorectal cancer
    • Kang MY, Lee BB, Kim YH, Chang DK, Kyu Park S, Chun HK, et al. Association of the SUV39H1 histone methyltransferase with the DNA methyltransferase 1 at mRNA expression level in primary colorectal cancer. International Journal of Cancer 2007;121:2192-7.
    • (2007) International Journal of Cancer , vol.121 , pp. 2192-2197
    • Kang, M.Y.1    Lee, B.B.2    Kim, Y.H.3    Chang, D.K.4    Kyu Park, S.5    Chun, H.K.6
  • 69
    • 33646562250 scopus 로고    scopus 로고
    • Modulation of cellular radiation responses by histone deacetylase inhibitors
    • DOI 10.1038/sj.onc.1209417, PII 1209417
    • Karagiannis TC, El-Osta A. Modulation of cellular radiation responses by histone deacetylase inhibitors. Oncogene 2006;25:3885-93. (Pubitemid 43990743)
    • (2006) Oncogene , vol.25 , Issue.28 , pp. 3885-3893
    • Karagiannis, T.C.1    El-Osta, A.2
  • 70
    • 80054681545 scopus 로고    scopus 로고
    • In vivo identification of tumor-suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma
    • Karreth FA, Tay Y, Perna D, Ala U, Tan SM, Rust AG, et al. In vivo identification of tumor-suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma. Cell 2011;147:382-95.
    • (2011) Cell , vol.147 , pp. 382-395
    • Karreth, F.A.1    Tay, Y.2    Perna, D.3    Ala, U.4    Tan, S.M.5    Rust, A.G.6
  • 73
    • 0018876427 scopus 로고
    • Effects of sodium butyrate and dimethylsulfoxide on biochemical properties of human colon cancer cells
    • Kim YS, Tsao D, Siddiqui B, Whitehead JS, Arnstein P, Bennett J, et al. Effects of sodium butyrate and dimethylsulfoxide on biochemical properties of human colon cancer cells. Cancer 1980;45:1185-92. (Pubitemid 10125129)
    • (1980) Cancer , vol.45 , Issue.5 SUPPL. , pp. 1185-1192
    • Kim, Y.S.1    Tsao, D.2    Siddiqui, B.3
  • 76
    • 0035522894 scopus 로고    scopus 로고
    • Two genetic hits (more or less) to cancer
    • Knudson AG. Two genetic hits (more or less) to cancer. Nature Reviews Cancer 2001;1:157-62. (Pubitemid 33741891)
    • (2001) Nature Reviews Cancer , vol.1 , Issue.2 , pp. 157-162
    • Knudson, A.G.1
  • 77
    • 77956296864 scopus 로고    scopus 로고
    • The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer
    • Kodach LL, Jacobs RJ, Heijmans J, van Noesel CJ, Langers AM, Verspaget HW, et al. The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer. Carcinogenesis 2010;31:1567-75.
    • (2010) Carcinogenesis , vol.31 , pp. 1567-1575
    • Kodach, L.L.1    Jacobs, R.J.2    Heijmans, J.3    Van Noesel, C.J.4    Langers, A.M.5    Verspaget, H.W.6
  • 78
    • 80054029971 scopus 로고    scopus 로고
    • Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers
    • Kogo R, Shimamura T, Mimori K, Kawahara K, Imoto S, Sudo T, et al. Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers. Cancer Research 2011;71:6320-6.
    • (2011) Cancer Research , vol.71 , pp. 6320-6326
    • Kogo, R.1    Shimamura, T.2    Mimori, K.3    Kawahara, K.4    Imoto, S.5    Sudo, T.6
  • 79
    • 34250634050 scopus 로고    scopus 로고
    • Targeting aberrant chromatin structure in colorectal carcinomas
    • Konishi K, Issa JP. Targeting aberrant chromatin structure in colorectal carcinomas. Cancer Journal 2007;13:49-55.
    • (2007) Cancer Journal , vol.13 , pp. 49-55
    • Konishi, K.1    Issa, J.P.2
  • 80
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin Modifications and Their Function
    • DOI 10.1016/j.cell.2007.02.005, PII S0092867407001845
    • Kouzarides T. Chromatin modifications and their function. Cell 2007;128:693-705. (Pubitemid 46273577)
    • (2007) Cell , vol.128 , Issue.4 , pp. 693-705
    • Kouzarides, T.1
  • 81
    • 35548934558 scopus 로고    scopus 로고
    • MLL translocations, histone modifications and leukaemia stem-cell development
    • DOI 10.1038/nrc2253, PII NRC2253
    • Krivtsov AV, Armstrong SA. MLL translocations, histone modifications and leukaemia stem-cell development. Nature Reviews Cancer 2007;7:823-33. (Pubitemid 350006257)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.11 , pp. 823-833
    • Krivtsov, A.V.1    Armstrong, S.A.2
  • 82
    • 36348996694 scopus 로고    scopus 로고
    • The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3
    • DOI 10.1158/0008-5472.CAN-07-1132
    • Kunizaki M, Hamamoto R, Silva FP, Yamaguchi K, Nagayasu T, Shibuya M, et al. The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3. Cancer Research 2007;67:10759-65. (Pubitemid 350145903)
    • (2007) Cancer Research , vol.67 , Issue.22 , pp. 10759-10765
    • Kunizaki, M.1    Hamamoto, R.2    Silva, F.P.3    Yamaguchi, K.4    Nagayasu, T.5    Shibuya, M.6    Nakamura, Y.7    Furukawa, Y.8
  • 84
    • 77953934846 scopus 로고    scopus 로고
    • Derepression of CLDN3 and CLDN4 during ovarian tumorigenesis is associated with loss of repressive histone modifications
    • Kwon MJ, Kim SS, Choi YL, Jung HS, Balch C, Kim SH, et al. Derepression of CLDN3 and CLDN4 during ovarian tumorigenesis is associated with loss of repressive histone modifications. Carcinogenesis 2010;31:974-83.
    • (2010) Carcinogenesis , vol.31 , pp. 974-983
    • Kwon, M.J.1    Kim, S.S.2    Choi, Y.L.3    Jung, H.S.4    Balch, C.5    Kim, S.H.6
  • 85
    • 84862909158 scopus 로고    scopus 로고
    • TCF12 protein functions as transcriptional repressor of E-cadherin, and its overexpression is correlated with metastasis of colorectal cancer
    • Lee CC, Chen WS, Chen CC, Chen LL, Lin YS, Fan CS, et al. TCF12 protein functions as transcriptional repressor of E-cadherin, and its overexpression is correlated with metastasis of colorectal cancer. Journal of Biological Chemistry 2012;287:2798-809.
    • (2012) Journal of Biological Chemistry , vol.287 , pp. 2798-2809
    • Lee, C.C.1    Chen, W.S.2    Chen, C.C.3    Chen, L.L.4    Lin, Y.S.5    Fan, C.S.6
  • 87
    • 79953324791 scopus 로고    scopus 로고
    • Transcriptional silencing of N-Myc downstream-regulated gene 1 (NDRG1) in metastatic colon cancer cell line SW620
    • Li Q, Chen H. Transcriptional silencing of N-Myc downstream-regulated gene 1 (NDRG1) in metastatic colon cancer cell line SW620. Clinical and Experimental Metastasis 2011;28:127-35.
    • (2011) Clinical and Experimental Metastasis , vol.28 , pp. 127-135
    • Li, Q.1    Chen, H.2
  • 88
    • 44049102711 scopus 로고    scopus 로고
    • Histone H3 (lys-9) deacetylation is associated with transcriptional silencing of E-cadherin in colorectal cancer cell lines
    • DOI 10.1080/07357900701837168, PII 792909407
    • Liu Y, Hong Y, Zhao Y, Ismail TM, Wong Y, Eu KW, et al. Histone H3 (lys-9) deacetylation is associated with transcriptional silencing of E-cadherin in colorectal cancer cell lines. Cancer Investigation 2008;26:575-82. (Pubitemid 351918577)
    • (2008) Cancer Investigation , vol.26 , Issue.6 , pp. 575-582
    • Liu, Y.1    Hong, Y.2    Zhao, Y.3    Ismail, T.M.4    Wong, Y.5    Eu, K.W.6
  • 90
    • 0035942170 scopus 로고    scopus 로고
    • Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia
    • DOI 10.1073/pnas.101617298
    • Magdinier F, Wolffe AP. Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia. Proceedings of the National Academy of Sciences of the United States of America 2001;98:4990-5. (Pubitemid 32397070)
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , Issue.9 , pp. 4990-4995
    • Magdinier, F.1    Wolffe, A.P.2
  • 91
    • 42149162792 scopus 로고    scopus 로고
    • HDACs and HDAC inhibitors in colon cancer
    • Mariadason JM. HDACs and HDAC inhibitors in colon cancer. Epigenetics 2008a;3:28-37. (Pubitemid 351540961)
    • (2008) Epigenetics , vol.3 , Issue.1 , pp. 28-37
    • Mariadason, J.M.1
  • 92
    • 55249099765 scopus 로고    scopus 로고
    • Making sense of HDAC2 mutations in colon cancer
    • Mariadason JM. Making sense of HDAC2 mutations in colon cancer. Gastroenterology 2008b;135:1457-9.
    • (2008) Gastroenterology , vol.135 , pp. 1457-1459
    • Mariadason, J.M.1
  • 93
    • 27644589675 scopus 로고    scopus 로고
    • The diverse functions of histone lysine methylation
    • DOI 10.1038/nrm1761, PII N1761
    • Martin C, Zhang Y. The diverse functions of histone lysine methylation. Nature Reviews Molecular Cell Biology 2005;6:838-49. (Pubitemid 41568733)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.11 , pp. 838-849
    • Martin, C.1    Zhang, Y.2
  • 96
    • 63449140634 scopus 로고    scopus 로고
    • The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways
    • Mattera L, Escaffit F, Pillaire MJ, Selves J, Tyteca S, Hoffmann JS, et al. The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways. Oncogene 2009;28:1506-17.
    • (2009) Oncogene , vol.28 , pp. 1506-1517
    • Mattera, L.1    Escaffit, F.2    Pillaire, M.J.3    Selves, J.4    Tyteca, S.5    Hoffmann, J.S.6
  • 97
    • 34347233479 scopus 로고    scopus 로고
    • DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2
    • DOI 10.1158/0008-5472.CAN-06-2029
    • McGarvey KM, Greene E, Fahrner JA, Jenuwein T, Baylin SB. DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2. Cancer Research 2007;67:5097-102. (Pubitemid 46997244)
    • (2007) Cancer Research , vol.67 , Issue.11 , pp. 5097-5102
    • McGarvey, K.M.1    Greene, E.2    Fahrner, J.A.3    Jenuwein, T.4    Baylin, S.B.5
  • 98
    • 17144412566 scopus 로고    scopus 로고
    • Clinical significance of enhancer of zeste homolog 2 expression in colorectal cancer cases
    • DOI 10.1016/j.ejso.2004.11.001, PII S0748798304003233
    • Mimori K, Ogawa K, Okamoto M, Sudo T, Inoue H, Mori M. Clinical significance of enhancer of zeste homolog 2 expression in colorectal cancer cases. European Journal of Surgical Oncology 2005;31:376-80. (Pubitemid 40521303)
    • (2005) European Journal of Surgical Oncology , vol.31 , Issue.4 , pp. 376-380
    • Mimori, K.1    Ogawa, K.2    Okamoto, M.3    Sudo, T.4    Inoue, H.5    Mori, M.6
  • 100
    • 79961148308 scopus 로고    scopus 로고
    • Long term transcriptional reactivation of epigenetically silenced genes in colorectal cancer cells requires DNA hypomethylation and histone acetylation
    • Mossman D, Scott RJ. Long term transcriptional reactivation of epigenetically silenced genes in colorectal cancer cells requires DNA hypomethylation and histone acetylation. PLoS One 2011;6:e23127.
    • (2011) PLoS One , vol.6
    • Mossman, D.1    Scott, R.J.2
  • 102
    • 38449100788 scopus 로고    scopus 로고
    • Expression profile of class I histone deacetylases in human cancer tissues
    • Nakagawa M, Oda Y, Eguchi T, Aishima S, Yao T, Hosoi F, et al. Expression profile of class I histone deacetylases in human cancer tissues. Oncology Reports 2007;18:769-74.
    • (2007) Oncology Reports , vol.18 , pp. 769-774
    • Nakagawa, M.1    Oda, Y.2    Eguchi, T.3    Aishima, S.4    Yao, T.5    Hosoi, F.6
  • 104
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • DOI 10.1038/30764
    • Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN, et al. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 1998;393:386-9. (Pubitemid 28269714)
    • (1998) Nature , vol.393 , Issue.6683 , pp. 386-389
    • Nan, X.1    Ng, H.-H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6    Bird, A.7
  • 105
    • 0037112369 scopus 로고    scopus 로고
    • Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2′- deoxycytidine
    • Nguyen CT, Weisenberger DJ, Velicescu M, Gonzales FA, Lin JC, Liang G, et al. Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2′-deoxycytidine. Cancer Research 2002;62:6456-61. (Pubitemid 35364106)
    • (2002) Cancer Research , vol.62 , Issue.22 , pp. 6456-6461
    • Nguyen, C.T.1    Weisenberger, D.J.2    Velicescu, M.3    Gonzales, F.A.4    Lin, J.C.Y.5    Liang, G.6    Jones, P.A.7
  • 107
    • 67650691722 scopus 로고    scopus 로고
    • SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer
    • Nosho K, Shima K, Irahara N, Kure S, Firestein R, Baba Y, et al. SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer. Modern Pathology 2009;22:922-32.
    • (2009) Modern Pathology , vol.22 , pp. 922-932
    • Nosho, K.1    Shima, K.2    Irahara, N.3    Kure, S.4    Firestein, R.5    Baba, Y.6
  • 108
    • 79956058282 scopus 로고    scopus 로고
    • A coactivator role of CARM1 in the dysregulation of beta-catenin activity in colorectal cancer cell growth and gene expression
    • Ou CY, LaBonte MJ, Manegold PC, So AY, Ianculescu I, Gerke DS, et al. A coactivator role of CARM1 in the dysregulation of beta-catenin activity in colorectal cancer cell growth and gene expression. Molecular Cancer Research 2011;9:660-70.
    • (2011) Molecular Cancer Research , vol.9 , pp. 660-670
    • Ou, C.Y.1    LaBonte, M.J.2    Manegold, P.C.3    So, A.Y.4    Ianculescu, I.5    Gerke, D.S.6
  • 111
    • 78649953952 scopus 로고    scopus 로고
    • Epigenetic silencing of peroxisome proliferator-activated receptor gamma is a biomarker for colorectal cancer progression and adverse patients' outcome
    • Pancione M, Sabatino L, Fucci A, Carafa V, Nebbioso A, Forte N, et al. Epigenetic silencing of peroxisome proliferator-activated receptor gamma is a biomarker for colorectal cancer progression and adverse patients' outcome. PLoS One 2010;5:e14229.
    • (2010) PLoS One , vol.5
    • Pancione, M.1    Sabatino, L.2    Fucci, A.3    Carafa, V.4    Nebbioso, A.5    Forte, N.6
  • 114
    • 33748868126 scopus 로고    scopus 로고
    • The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas
    • Pena C, Garcia JM, Garcia V, Silva J, Dominguez G, Rodriguez R, et al. The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas. International Journal of Cancer 2006;119:2098-104.
    • (2006) International Journal of Cancer , vol.119 , pp. 2098-2104
    • Pena, C.1    Garcia, J.M.2    Garcia, V.3    Silva, J.4    Dominguez, G.5    Rodriguez, R.6
  • 116
    • 0034283031 scopus 로고    scopus 로고
    • Frequent frameshift mutations of RIZ in sporadic gastrointestinal and endometrial carcinomas with microsatellite instability
    • Piao Z, Fang W, Malkhosyan S, Kim H, Horii A, Perucho M, et al. Frequent frameshift mutations of RIZ in sporadic gastrointestinal and endometrial carcinomas with microsatellite instability. Cancer Research 2000;60:4701-4.
    • (2000) Cancer Research , vol.60 , pp. 4701-4704
    • Piao, Z.1    Fang, W.2    Malkhosyan, S.3    Kim, H.4    Horii, A.5    Perucho, M.6
  • 117
    • 33646142159 scopus 로고    scopus 로고
    • Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats
    • DOI 10.1093/carcin/bgi364
    • Pogribny IP, Ross SA, Tryndyak VP, Pogribna M, Poirier LA, Karpinets TV. Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats. Carcinogenesis 2006;27:1180-6. (Pubitemid 43985433)
    • (2006) Carcinogenesis , vol.27 , Issue.6 , pp. 1180-1186
    • Pogribny, I.P.1    Ross, S.A.2    Tryndyak, V.P.3    Pogribna, M.4    Poirier, L.A.5    Karpinets, T.V.6
  • 118
    • 33645768490 scopus 로고    scopus 로고
    • Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation
    • Pruitt K, Zinn RL, Ohm JE, McGarvey KM, Kang SH, Watkins DN, et al. Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation. PLoS Genetics 2006;2:e40.
    • (2006) PLoS Genetics , vol.2
    • Pruitt, K.1    Zinn, R.L.2    Ohm, J.E.3    McGarvey, K.M.4    Kang, S.H.5    Watkins, D.N.6
  • 119
    • 66449121883 scopus 로고    scopus 로고
    • Histone H3 lysine 27 trimethylation in adult differentiated colon associated to cancer DNA hypermethylation
    • Rada-Iglesias A, Enroth S, Andersson R, Wanders A, Pahlman L, Komorowski J, et al. Histone H3 lysine 27 trimethylation in adult differentiated colon associated to cancer DNA hypermethylation. Epigenetics 2009;4:107-13.
    • (2009) Epigenetics , vol.4 , pp. 107-113
    • Rada-Iglesias, A.1    Enroth, S.2    Andersson, R.3    Wanders, A.4    Pahlman, L.5    Komorowski, J.6
  • 120
    • 80053427396 scopus 로고    scopus 로고
    • Roles of the Polycomb group proteins in stem cells and cancer
    • Richly H, Aloia L, Di Croce L. Roles of the Polycomb group proteins in stem cells and cancer. Cell Death & Disease 2011;2:e204.
    • (2011) Cell Death & Disease , vol.2
    • Richly, H.1    Aloia, L.2    Di Croce, L.3
  • 121
    • 0017767153 scopus 로고
    • N-Butyrate causes histone modification in HeLa and Friend erythroleukaemia cells
    • Riggs MG, Whittaker RG, Neumann JR, Ingram VM. n-Butyrate causes histone modification in HeLa and Friend erythroleukaemia cells. Nature 1977;268:462-4.
    • (1977) Nature , vol.268 , pp. 462-464
    • Riggs, M.G.1    Whittaker, R.G.2    Neumann, J.R.3    Ingram, V.M.4
  • 122
    • 33646354640 scopus 로고    scopus 로고
    • A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition
    • Ropero S, Fraga MF, Ballestar E, Hamelin R, Yamamoto H, Boix-Chornet M, et al. A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition. Nature Genetics 2006;38:566-9.
    • (2006) Nature Genetics , vol.38 , pp. 566-569
    • Ropero, S.1    Fraga, M.F.2    Ballestar, E.3    Hamelin, R.4    Yamamoto, H.5    Boix-Chornet, M.6
  • 123
    • 0033945861 scopus 로고    scopus 로고
    • DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
    • DOI 10.1038/77023
    • Rountree MR, Bachman KE, Baylin SB. DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nature Genetics 2000;25: 269-77. (Pubitemid 30437311)
    • (2000) Nature Genetics , vol.25 , Issue.3 , pp. 269-277
    • Rountree, M.R.1    Bachman, K.E.2    Baylin, S.B.3
  • 124
    • 77953626157 scopus 로고    scopus 로고
    • Biology of colorectal cancer
    • Saif MW, Chu E. Biology of colorectal cancer. Cancer Journal 2010;16:196-201.
    • (2010) Cancer Journal , vol.16 , pp. 196-201
    • Saif, M.W.1    Chu, E.2
  • 125
  • 126
    • 0035168321 scopus 로고    scopus 로고
    • RIZ, the retinoblastoma protein interacting zinc finger gene, is mutated in genetically unstable cancers of the pancreas, stomach, and colorectum
    • Sakurada K, Furukawa T, Kato Y, Kayama T, Huang S, Horii A. RIZ, the retinoblastoma protein interacting zinc finger gene, is mutated in genetically unstable cancers of the pancreas, stomach, and colorectum. Genes, Chromosomes and Cancer 2001;30:207-11. (Pubitemid 32044603)
    • (2001) Genes Chromosomes and Cancer , vol.30 , Issue.2 , pp. 207-211
    • Sakurada, K.1    Furukawa, T.2    Kato, Y.3    Kayama, T.4    Huang, S.5    Horii, A.6
  • 127
    • 79961170994 scopus 로고    scopus 로고
    • A ceRNA hypothesis: The Rosetta Stone of a hidden RNA language
    • Salmena L, Poliseno L, Tay Y, Kats L, Pandolfi PP. A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language. Cell 2011;146:353-8.
    • (2011) Cell , vol.146 , pp. 353-358
    • Salmena, L.1    Poliseno, L.2    Tay, Y.3    Kats, L.4    Pandolfi, P.P.5
  • 128
    • 27544505676 scopus 로고    scopus 로고
    • Chromatin modifier enzymes, the histone code and cancer
    • DOI 10.1016/j.ejca.2005.08.010, PII S0959804905007100, Transcription Factors in Cancer
    • Santos-Rosa H, Caldas C. Chromatin modifier enzymes, the histone code and cancer. European Journal of Cancer 2005;41:2381-402. (Pubitemid 41540617)
    • (2005) European Journal of Cancer , vol.41 , Issue.16 , pp. 2381-2402
    • Santos-Rosa, H.1    Caldas, C.2
  • 132
    • 0031727248 scopus 로고    scopus 로고
    • Sodium butyrate induces retinoblastoma protein dephosphorylation, p16 expression and growth arrest of colon cancer cells
    • DOI 10.1023/A:1006831330340
    • Schwartz B, Avivi-Green C, Polak-Charcon S. Sodium butyrate induces retinoblastoma protein dephosphorylation, p16 expression and growth arrest of colon cancer cells. Molecular and Cellular Biochemistry 1998;188:21-30. (Pubitemid 28493314)
    • (1998) Molecular and Cellular Biochemistry , vol.188 , Issue.1-2 , pp. 21-30
    • Schwartz, B.1    Avivi-Green, C.2    Polak-Charcon, S.3
  • 134
    • 33644763022 scopus 로고    scopus 로고
    • The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes
    • DOI 10.1101/gad.1385806
    • Sierra J, Yoshida T, Joazeiro CA, Jones KA. The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes. Genes and Development 2006;20:586-600. (Pubitemid 43345324)
    • (2006) Genes and Development , vol.20 , Issue.5 , pp. 586-600
    • Sierra, J.1    Yoshida, T.2    Joazeiro, C.A.3    Jones, K.A.4
  • 135
    • 42549095632 scopus 로고    scopus 로고
    • Enhanced methyltransferase activity of SMYD3 by the cleavage of its N-terminal region in human cancer cells
    • DOI 10.1038/sj.onc.1210929, PII 1210929
    • Silva FP, Hamamoto R, Kunizaki M, Tsuge M, Nakamura Y, Furukawa Y. Enhanced methyltransferase activity of SMYD3 by the cleavage of its N-terminal region in human cancer cells. Oncogene 2008;27:2686-92. (Pubitemid 351581465)
    • (2008) Oncogene , vol.27 , Issue.19 , pp. 2686-2692
    • Silva, F.P.1    Hamamoto, R.2    Kunizaki, M.3    Tsuge, M.4    Nakamura, Y.5    Furukawa, Y.6
  • 138
    • 33750379420 scopus 로고    scopus 로고
    • Polycomb silencers control cell fate, development and cancer
    • DOI 10.1038/nrc1991, PII NRC1991
    • Sparmann A, van Lohuizen M. Polycomb silencers control cell fate, development and cancer. Nature Reviews Cancer 2006;11:846-56. (Pubitemid 44629896)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.11 , pp. 846-856
    • Sparmann, A.1    Van Lohuizen, M.2
  • 140
    • 79952538100 scopus 로고    scopus 로고
    • Lysine methylation of promoter-bound transcription factors and relevance to cancer
    • Stark GR, Wang Y, Lu T. Lysine methylation of promoter-bound transcription factors and relevance to cancer. Cell Research 2011;3:375-80.
    • (2011) Cell Research , vol.3 , pp. 375-380
    • Stark, G.R.1    Wang, Y.2    Lu, T.3
  • 142
    • 84555208820 scopus 로고    scopus 로고
    • Histone acetyltransferases and deacetylases: Molecular and clinical implications to gastrointestinal carcinogenesis
    • Shanghai
    • Sun WJ, Zhou X, Zheng JH, Lu MD, Nie JY, Yang XJ, et al. Histone acetyltransferases and deacetylases: molecular and clinical implications to gastrointestinal carcinogenesis. Acta Biochimica et Biophysica Sinica (Shanghai) 2012;44:80-91.
    • (2012) Acta Biochimica et Biophysica Sinica , vol.44 , pp. 80-91
    • Sun, W.J.1    Zhou, X.2    Zheng, J.H.3    Lu, M.D.4    Nie, J.Y.5    Yang, X.J.6
  • 144
    • 33644825262 scopus 로고    scopus 로고
    • Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage
    • DOI 10.1016/j.ccr.2006.02.016, PII S1535610806000535
    • Suzuki K, Suzuki I, Leodolter A, Alonso S, Horiuchi S, Yamashita K, et al. Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage. Cancer Cell 2006;9:199-207. (Pubitemid 43357946)
    • (2006) Cancer Cell , vol.9 , Issue.3 , pp. 199-207
    • Suzuki, K.1    Suzuki, I.2    Leodolter, A.3    Alonso, S.4    Horiuchi, S.5    Yamashita, K.6    Perucho, M.7
  • 145
    • 54349095323 scopus 로고    scopus 로고
    • G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription
    • Tachibana M, Matsumura Y, Fukuda M, Kimura H, Shinkai Y. G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription. EMBO Journal 2008;27:2681-90.
    • (2008) EMBO Journal , vol.27 , pp. 2681-2690
    • Tachibana, M.1    Matsumura, Y.2    Fukuda, M.3    Kimura, H.4    Shinkai, Y.5
  • 146
    • 79959267832 scopus 로고    scopus 로고
    • Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker
    • Takawa M, Masuda K, Kunizaki M, Daigo Y, Takagi K, Iwai Y, et al. Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker. Cancer Science 2011;102:1298-305.
    • (2011) Cancer Science , vol.102 , pp. 1298-1305
    • Takawa, M.1    Masuda, K.2    Kunizaki, M.3    Daigo, Y.4    Takagi, K.5    Iwai, Y.6
  • 148
    • 65549152323 scopus 로고    scopus 로고
    • PRMT5, a novel TRAIL receptor-binding protein, inhibits TRAIL-induced apoptosis via nuclear factor-kappaB activation
    • Tanaka H, Hoshikawa Y, Oh-hara T, Koike S, Naito M, Noda T, et al. PRMT5, a novel TRAIL receptor-binding protein, inhibits TRAIL-induced apoptosis via nuclear factor-kappaB activation. Molecular Cancer Research 2009;7:557-69.
    • (2009) Molecular Cancer Research , vol.7 , pp. 557-569
    • Tanaka, H.1    Hoshikawa, Y.2    Oh-hara, T.3    Koike, S.4    Naito, M.5    Noda, T.6
  • 150
    • 80054700538 scopus 로고    scopus 로고
    • Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs
    • Tay Y, Kats L, Salmena L, Weiss D, Tan SM, Ala U, et al. Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs. Cell 2011;147:344-57.
    • (2011) Cell , vol.147 , pp. 344-357
    • Tay, Y.1    Kats, L.2    Salmena, L.3    Weiss, D.4    Tan, S.M.5    Ala, U.6
  • 152
    • 27144496194 scopus 로고    scopus 로고
    • A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5′ flanking region of SMYD3 is a risk factor for human cancers
    • DOI 10.1038/ng1638, PII N1638
    • Tsuge M, Hamamoto R, Silva FP, Ohnishi Y, Chayama K, Kamatani N, et al. A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5′ flanking region of SMYD3 is a risk factor for human cancers. Nature Genetics 2005;37:1104-7. (Pubitemid 41486663)
    • (2005) Nature Genetics , vol.37 , Issue.10 , pp. 1104-1107
    • Tsuge, M.1    Hamamoto, R.2    Silva, F.P.3    Ohnishi, Y.4    Chayama, K.5    Kamatani, N.6    Furukawa, Y.7    Nakamura, Y.8
  • 161
    • 34548526743 scopus 로고    scopus 로고
    • Chromatin remodeling and cancer, part I: covalent histone modifications
    • DOI 10.1016/j.molmed.2007.07.003, PII S1471491407001463
    • Wang GG, Allis CD, Chi P. Chromatin remodeling and cancer, part I: covalent histone modifications. Trends in Molecular Medicine 2007;13:363-72. (Pubitemid 47385381)
    • (2007) Trends in Molecular Medicine , vol.13 , Issue.9 , pp. 363-372
    • Wang, G.G.1    Allis, C.D.2    Chi, P.3
  • 162
    • 80051899599 scopus 로고    scopus 로고
    • Differential gene expression signatures between colorectal cancers with and without KRAS mutations: Crosstalk between the KRAS pathway and other signalling pathways
    • Watanabe T, Kobunai T, Yamamoto Y, Matsuda K, Ishihara S, Nozawa K, et al. Differential gene expression signatures between colorectal cancers with and without KRAS mutations: crosstalk between the KRAS pathway and other signalling pathways. European Journal of Cancer 2011a;47:1946-54.
    • (2011) European Journal of Cancer , vol.47 , pp. 1946-1954
    • Watanabe, T.1    Kobunai, T.2    Yamamoto, Y.3    Matsuda, K.4    Ishihara, S.5    Nozawa, K.6
  • 163
    • 80051618706 scopus 로고    scopus 로고
    • Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer
    • Watanabe Y, Castoro RJ, Kim HS, North B, Oikawa R, Hiraishi T, et al. Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer. PLoS One 2011b;6:e23320.
    • (2011) PLoS One , vol.6
    • Watanabe, Y.1    Castoro, R.J.2    Kim, H.S.3    North, B.4    Oikawa, R.5    Hiraishi, T.6
  • 164
    • 41549159879 scopus 로고    scopus 로고
    • Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: Specific role of class I histone deacetylases in vitro and in vivo
    • DOI 10.1158/1078-0432.CCR-07-0990
    • Weichert W, Roske A, Niesporek S, Noske A, Buckendahl AC, Dietel M, et al. Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo. Clinical Cancer Research 2008;14:1669-77. (Pubitemid 351469450)
    • (2008) Clinical Cancer Research , vol.14 , Issue.6 , pp. 1669-1677
    • Weichert, W.1    Roske, A.2    Niesporek, S.3    Noske, A.4    Buckendahl, A.-C.5    Dietel, M.6    Gekeler, V.7    Boehm, M.8    Beckers, T.9    Denkert, C.10
  • 168
    • 18744372758 scopus 로고    scopus 로고
    • The influence of specific luminal factors on the colonic epithelium: High-dose butyrate and physical changes suppress early carcinogenic events in rats
    • DOI 10.1007/s10350-004-0810-x
    • Wong CS, Sengupta S, Tjandra JJ, Gibson PR. The influence of specific luminal factors on the colonic epithelium: high-dose butyrate and physical changes suppress early carcinogenic events in rats. Diseases of the Colon and Rectum 2005;48:549-59. (Pubitemid 40767879)
    • (2005) Diseases of the Colon and Rectum , vol.48 , Issue.3 , pp. 549-559
    • Wong, C.S.M.1    Sengupta, S.2    Tjandra, J.J.3    Gibson, P.R.4
  • 169
    • 38749095527 scopus 로고    scopus 로고
    • Validation of biomarkers associated with 5-fiuorouracil and thymidylate synthase in colorectal cancer
    • Xi Y, Formentini A, Nakajima G, Kornmann M, Ju J. Validation of biomarkers associated with 5-fluorouracil and thymidylate synthase in colorectal cancer. Oncology Reports 2008;19:257-62. (Pubitemid 351176158)
    • (2008) Oncology Reports , vol.19 , Issue.1 , pp. 257-262
    • Xi, Y.1    Formentini, A.2    Nakajima, G.3    Kornmann, M.4    Ju, J.5
  • 170
    • 2342599619 scopus 로고    scopus 로고
    • The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases
    • Yang XJ. The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases. Nucleic Acids Research 2004;32:959-76.
    • (2004) Nucleic Acids Research , vol.32 , pp. 959-976
    • Yang, X.J.1
  • 171
    • 12244251445 scopus 로고    scopus 로고
    • Stat3 dimerization regulated by reversible acetylation of a single lysine residue
    • DOI 10.1126/science.1105166
    • Yuan ZL, Guan YJ, Chatterjee D, Chin YE. Stat3 dimerization regulated by reversible acetylation of a single lysine residue. Science 2005;307:269-73. (Pubitemid 40116244)
    • (2005) Science , vol.307 , Issue.5707 , pp. 269-273
    • Yuan, Z.-L.1    Guan, Y.-J.2    Chatterjee, D.3    Chin, Y.E.4
  • 172
    • 62049086288 scopus 로고    scopus 로고
    • PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing
    • Zhao Q, Rank G, Tan YT, Li H, Moritz RL, Simpson RJ, et al. PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing. Nature Structural & Molecular Biology 2009;16:304-11.
    • (2009) Nature Structural & Molecular Biology , vol.16 , pp. 304-311
    • Zhao, Q.1    Rank, G.2    Tan, Y.T.3    Li, H.4    Moritz, R.L.5    Simpson, R.J.6
  • 173
    • 2342603414 scopus 로고    scopus 로고
    • Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis
    • DOI 10.1016/S1535-6108(04)00114-X, PII S153561080400114X
    • Zhu P, Martin E, Mengwasser J, Schlag P, Janssen KP, Gottlicher M. Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis. Cancer Cell 2004;5:455-63. (Pubitemid 38610247)
    • (2004) Cancer Cell , vol.5 , Issue.5 , pp. 455-463
    • Zhu, P.1    Martin, E.2    Mengwasser, J.3    Schlag, P.4    Janssen, K.-P.5    Gottlicher, M.6
  • 175
    • 57649137961 scopus 로고    scopus 로고
    • Chromatin modification requirements for 15-lipoxygenase-1 transcriptional reactivation in colon cancer cells
    • Zuo X, Morris JS, Shureiqi I. Chromatin modification requirements for 15-lipoxygenase-1 transcriptional reactivation in colon cancer cells. Journal of Biological Chemistry 2008;283:31341-7.
    • (2008) Journal of Biological Chemistry , vol.283 , pp. 31341-31347
    • Zuo, X.1    Morris, J.S.2    Shureiqi, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.