-
1
-
-
0032499756
-
P21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells
-
Archer S.Y., Meng S., Shei A., Hodin R.A. p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells. Proc. Natl. Acad. Sci. USA. 95:1998;6791-6796.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6791-6796
-
-
Archer, S.Y.1
Meng, S.2
Shei, A.3
Hodin, R.A.4
-
2
-
-
0038494686
-
Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase-8-mediated apoptosis and downregulation of c-FLIP protein
-
Aron J.L., Parthun M.R., Marcucci G., Kitada S., Mone A.P., Davis M.E., Shen T., Murphy T., Wickham J., Kanakry C.et al. Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase-8-mediated apoptosis and downregulation of c-FLIP protein. Blood. 102:2003;652-658.
-
(2003)
Blood
, vol.102
, pp. 652-658
-
-
Aron, J.L.1
Parthun, M.R.2
Marcucci, G.3
Kitada, S.4
Mone, A.P.5
Davis, M.E.6
Shen, T.7
Murphy, T.8
Wickham, J.9
Kanakry, C.10
-
3
-
-
0034802325
-
Up-regulation of p21(WAF1/CIP1) by histone deacetylase inhibitors reduces their cytotoxicity
-
Burgess A.J., Pavey S., Warrener R., Hunter L.J., Piva T.J., Musgrove E.A., Saunders N., Parsons P.G., Gabrielli B.G. Up-regulation of p21(WAF1/CIP1) by histone deacetylase inhibitors reduces their cytotoxicity. Mol. Pharmacol. 60:2001;828-837.
-
(2001)
Mol. Pharmacol.
, vol.60
, pp. 828-837
-
-
Burgess, A.J.1
Pavey, S.2
Warrener, R.3
Hunter, L.J.4
Piva, T.J.5
Musgrove, E.A.6
Saunders, N.7
Parsons, P.G.8
Gabrielli, B.G.9
-
4
-
-
18644367141
-
Induction and superinduction of growth arrest and DNA damage gene 45 (GADD45) alpha and beta messenger RNAs by histone deacetylase inhibitors trichostatin A (TSA) and butyrate in SW620 human colon carcinoma cells
-
Chen Z., Clark S., Birkeland M., Sung C.M., Lago A., Liu R., Kirkpatrick R., Johanson K., Winkler J.D., Hu E. Induction and superinduction of growth arrest and DNA damage gene 45 (GADD45) alpha and beta messenger RNAs by histone deacetylase inhibitors trichostatin A (TSA) and butyrate in SW620 human colon carcinoma cells. Cancer Lett. 188:2002;127-140.
-
(2002)
Cancer Lett.
, vol.188
, pp. 127-140
-
-
Chen, Z.1
Clark, S.2
Birkeland, M.3
Sung, C.M.4
Lago, A.5
Liu, R.6
Kirkpatrick, R.7
Johanson, K.8
Winkler, J.D.9
Hu, E.10
-
5
-
-
0037108309
-
Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment
-
Daskalakis M., Nguyen T.T., Nguyen C., Guldberg P., Kohler G., Wijermans P., Jones P.A., Lubbert M. Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment. Blood. 100:2002;2957-2964.
-
(2002)
Blood
, vol.100
, pp. 2957-2964
-
-
Daskalakis, M.1
Nguyen, T.T.2
Nguyen, C.3
Guldberg, P.4
Kohler, G.5
Wijermans, P.6
Jones, P.A.7
Lubbert, M.8
-
6
-
-
0038527642
-
Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor
-
Di Croce L., Raker V.A., Corsaro M., Fazi F., Fanelli M., Faretta M., Fuks F., Lo Coco F., Kouzarides T., Nervi C.et al. Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science. 295:2002;1079-1082.
-
(2002)
Science
, vol.295
, pp. 1079-1082
-
-
Di Croce, L.1
Raker, V.A.2
Corsaro, M.3
Fazi, F.4
Fanelli, M.5
Faretta, M.6
Fuks, F.7
Lo Coco, F.8
Kouzarides, T.9
Nervi, C.10
-
7
-
-
0035132140
-
Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia
-
Ferrara F.F., Fazi F., Bianchini A., Padula F., Gelmetti V., Minucci S., Mancini M., Pelicci P.G., Lo Coco F., Nervi C. Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia. Cancer Res. 61:2001;2-7.
-
(2001)
Cancer Res.
, vol.61
, pp. 2-7
-
-
Ferrara, F.F.1
Fazi, F.2
Bianchini, A.3
Padula, F.4
Gelmetti, V.5
Minucci, S.6
Mancini, M.7
Pelicci, P.G.8
Lo Coco, F.9
Nervi, C.10
-
8
-
-
0042905956
-
Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: Defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines
-
Glaser K.B., Staver M.J., Waring J.F., Stender J., Ulrich R.G., Davidsen S.K. Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors. Defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines Mol. Cancer Ther. 2:2003;151-163.
-
(2003)
Mol. Cancer Ther.
, vol.2
, pp. 151-163
-
-
Glaser, K.B.1
Staver, M.J.2
Waring, J.F.3
Stender, J.4
Ulrich, R.G.5
Davidsen, S.K.6
-
9
-
-
18244383806
-
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
-
Gottlicher M., Minucci S., Zhu P., Kramer O.H., Schimpf A., Giavara S., Sleeman J.P., Lo Coco F., Nervi C., Pelicci P.G., Heinzel T. Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J. 20:2001;6969-6978.
-
(2001)
EMBO J.
, vol.20
, pp. 6969-6978
-
-
Gottlicher, M.1
Minucci, S.2
Zhu, P.3
Kramer, O.H.4
Schimpf, A.5
Giavara, S.6
Sleeman, J.P.7
Lo Coco, F.8
Nervi, C.9
Pelicci, P.G.10
Heinzel, T.11
-
10
-
-
0036008097
-
Deacetylase enzymes: Biological functions and the use of small-molecule inhibitors
-
Grozinger C.M., Schreiber S.L. Deacetylase enzymes. biological functions and the use of small-molecule inhibitors Chem. Biol. 9:2002;3-16.
-
(2002)
Chem. Biol.
, vol.9
, pp. 3-16
-
-
Grozinger, C.M.1
Schreiber, S.L.2
-
11
-
-
0344640906
-
Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation
-
Haggarty S.J., Koeller K.M., Wong J.C., Grozinger C.M., Schreiber S.L. Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation. Proc. Natl. Acad. Sci. USA. 100:2003;4389-4394.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4389-4394
-
-
Haggarty, S.J.1
Koeller, K.M.2
Wong, J.C.3
Grozinger, C.M.4
Schreiber, S.L.5
-
12
-
-
0035189761
-
Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia
-
He L.Z., Tolentino T., Grayson P., Zhong S., Warrell R.P. Jr., Rifkind R.A., Marks P.A., Richon V.M., Pandolfi P.P. Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia. J. Clin. Invest. 108:2001;1321-1330.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1321-1330
-
-
He, L.Z.1
Tolentino, T.2
Grayson, P.3
Zhong, S.4
Warrell R.P., Jr.5
Rifkind, R.A.6
Marks, P.A.7
Richon, V.M.8
Pandolfi, P.P.9
-
13
-
-
0038485588
-
Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA)
-
Henderson C., Mizzau M., Paroni G., Maestro R., Schneider C., Brancolini C. Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA). J. Biol. Chem. 278:2003;12579-12589.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12579-12589
-
-
Henderson, C.1
Mizzau, M.2
Paroni, G.3
Maestro, R.4
Schneider, C.5
Brancolini, C.6
-
14
-
-
0037161744
-
HDAC6 is a microtubule-associated deacetylase
-
Hubbert C., Guardiola A., Shao R., Kawaguchi Y., Ito A., Nixon A., Yoshida M., Wang X.F., Yao T.P. HDAC6 is a microtubule-associated deacetylase. Nature. 417:2002;455-458.
-
(2002)
Nature
, vol.417
, pp. 455-458
-
-
Hubbert, C.1
Guardiola, A.2
Shao, R.3
Kawaguchi, Y.4
Ito, A.5
Nixon, A.6
Yoshida, M.7
Wang, X.F.8
Yao, T.P.9
-
15
-
-
0036828101
-
MS-27-275, an inhibitor of histone deacetylase, has marked in vitro and in vivo antitumor activity against pediatric solid tumors
-
Jaboin J., Wild J., Hamidi H., Khanna C., Kim C.J., Robey R., Bates S.E., Thiele C.J. MS-27-275, an inhibitor of histone deacetylase, has marked in vitro and in vivo antitumor activity against pediatric solid tumors. Cancer Res. 62:2002;6108-6115.
-
(2002)
Cancer Res.
, vol.62
, pp. 6108-6115
-
-
Jaboin, J.1
Wild, J.2
Hamidi, H.3
Khanna, C.4
Kim, C.J.5
Robey, R.6
Bates, S.E.7
Thiele, C.J.8
-
16
-
-
0035839136
-
Translating the histone code
-
Jenuwein T., Allis C.D. Translating the histone code. Science. 293:2001;1074-1080.
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
17
-
-
0036527775
-
Histone-deacetylase inhibitors: Novel drugs for the treatment of cancer
-
Johnstone R.W. Histone-deacetylase inhibitors. novel drugs for the treatment of cancer Nat. Rev. Drug Discov. 1:2002;287-299.
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 287-299
-
-
Johnstone, R.W.1
-
18
-
-
0037169358
-
Apoptosis: A link between cancer genetics and chemotherapy
-
Johnstone R.W., Ruefli A.A., Lowe S.W. Apoptosis. a link between cancer genetics and chemotherapy Cell. 108:2002;153-164.
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
-
19
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones P.A., Baylin S.B. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3:2002;415-428.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
21
-
-
0037093346
-
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
-
Langley E., Pearson M., Faretta M., Bauer U.M., Frye R.A., Minucci S., Pelicci P.G., Kouzarides T. Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. EMBO J. 21:2002;2383-2396.
-
(2002)
EMBO J.
, vol.21
, pp. 2383-2396
-
-
Langley, E.1
Pearson, M.2
Faretta, M.3
Bauer, U.M.4
Frye, R.A.5
Minucci, S.6
Pelicci, P.G.7
Kouzarides, T.8
-
22
-
-
0034662614
-
Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: Comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer
-
Mariadason J.M., Corner G.A., Augenlicht L.H. Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids. comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer Cancer Res. 60:2000;4561-4572.
-
(2000)
Cancer Res.
, vol.60
, pp. 4561-4572
-
-
Mariadason, J.M.1
Corner, G.A.2
Augenlicht, L.H.3
-
23
-
-
0036014986
-
Histone deacetylases as therapeutic targets in hematologic malignancies
-
Melnick A., Licht J.D. Histone deacetylases as therapeutic targets in hematologic malignancies. Curr. Opin. Hematol. 9:2002;322-332.
-
(2002)
Curr. Opin. Hematol.
, vol.9
, pp. 322-332
-
-
Melnick, A.1
Licht, J.D.2
-
24
-
-
0037589018
-
Molecular sequelae of histone deacetylase inhibition in human malignant B cells
-
Mitsiades N., Mitsiades C.S., Richardson P.G., McMullan C., Poulaki V., Fanourakis G., Schlossman R., Chauhan D., Munshi N.C., Hideshima T.et al. Molecular sequelae of histone deacetylase inhibition in human malignant B cells. Blood. 101:2003;4055-4062.
-
(2003)
Blood
, vol.101
, pp. 4055-4062
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Richardson, P.G.3
McMullan, C.4
Poulaki, V.5
Fanourakis, G.6
Schlossman, R.7
Chauhan, D.8
Munshi, N.C.9
Hideshima, T.10
-
25
-
-
0037291214
-
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
-
North B.J., Marshall B.L., Borra M.T., Denu J.M., Verdin E. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol. Cell. 11:2003;437-444.
-
(2003)
Mol. Cell
, vol.11
, pp. 437-444
-
-
North, B.J.1
Marshall, B.L.2
Borra, M.T.3
Denu, J.M.4
Verdin, E.5
-
26
-
-
0034086168
-
Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells
-
Qiu L., Burgess A., Fairlie D.P., Leonard H., Parsons P.G., Gabrielli B.G. Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells. Mol. Biol. Cell. 11:2000;2069-2083.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 2069-2083
-
-
Qiu, L.1
Burgess, A.2
Fairlie, D.P.3
Leonard, H.4
Parsons, P.G.5
Gabrielli, B.G.6
-
27
-
-
0034730127
-
Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation
-
Richon V.M., Sandhoff T.W., Rifkind R.A., Marks P.A. Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation. Proc. Natl. Acad. Sci. USA. 97:2000;10014-10019.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10014-10019
-
-
Richon, V.M.1
Sandhoff, T.W.2
Rifkind, R.A.3
Marks, P.A.4
-
28
-
-
0035845541
-
The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species
-
Ruefli A.A., Ausserlechner M.J., Bernhard D., Sutton V.R., Tainton K.M., Kofler R., Smyth M.J., Johnstone R.W. The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species. Proc. Natl. Acad. Sci. USA. 98:2001;10833-10838.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10833-10838
-
-
Ruefli, A.A.1
Ausserlechner, M.J.2
Bernhard, D.3
Sutton, V.R.4
Tainton, K.M.5
Kofler, R.6
Smyth, M.J.7
Johnstone, R.W.8
-
29
-
-
0035147369
-
Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases
-
Taddei A., Maison C., Roche D., Almouzni G. Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases. Nat. Cell Biol. 3:2001;114-120.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 114-120
-
-
Taddei, A.1
Maison, C.2
Roche, D.3
Almouzni, G.4
-
30
-
-
0012508834
-
Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma
-
Yamashita K., Upadhyay S., Osada M., Hoque M.O., Xiao Y., Mori M., Sato F., Meltzer S.J., Sidransky D. Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma. Cancer Cell. 2:2002;485-495.
-
(2002)
Cancer Cell
, vol.2
, pp. 485-495
-
-
Yamashita, K.1
Upadhyay, S.2
Osada, M.3
Hoque, M.O.4
Xiao, Y.5
Mori, M.6
Sato, F.7
Meltzer, S.J.8
Sidransky, D.9
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