Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27

Genes and Development

Volumn 18, Issue 13, 2004, Pages 1592-1605

  Kirmizis, Antonis ^a   Bartley, Stephanie M ^a   Kuzmichev, Andrei ^b   Margueron, Raphael ^b   Reinberg, Danny ^b   Green, Roland ^c   Farnham, Peggy J ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c Roche NimbleGen Inc   (United States)

Author keywords

Chromatin immunoprecipitation; Eed; Histone methylation; Polycomb; RNA interference; Suz12

Indexed keywords

DNA; EMBRYONIC ECTODERM DEVELOPMENT PROTEIN; HISTONE H3; HISTONE LYSINE METHYLTRANSFERASE; LYSINE; POLYCOMB GROUP PROTEIN; POLYCOMB REPRESSIVE COMPLEX 2 PROTEIN; POLYCOMB REPRESSIVE COMPLEX 3 PROTEIN; PROTEIN EZH2; PROTEIN SUZ12; REGULATOR PROTEIN; REPRESSOR PROTEIN; RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CPG ISLAND; DNA MICROARRAY; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN LOCALIZATION; PROTEIN METHYLATION; RNA ANALYSIS; TRANSCRIPTION REGULATION;

CARRIER PROTEINS; COLONIC NEOPLASMS; CPG ISLANDS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENE SILENCING; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; LYSINE; MACROMOLECULAR SUBSTANCES; METHYLATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS (GENETICS); PROTEINS; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS;

EID: 3042781030     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1200204     Document Type: Article

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