-
1
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128: 683-92.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
3
-
-
33947315736
-
Cancer epigenomics: DNA methylomes and histonemodification maps
-
Esteller M. Cancer epigenomics: DNA methylomes and histonemodification maps. Nat Rev Genet 2007; 8: 286-98.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 286-298
-
-
Esteller, M.1
-
4
-
-
0033535478
-
X-chromosome inactivation
-
Lyon MF. X-chromosome inactivation. Curr Biol 1999; 9: R235-7.
-
(1999)
Curr Biol
, vol.9
-
-
Lyon, M.F.1
-
5
-
-
58549109636
-
X chromosome dosage compensation: How mammals keep the balance
-
Payer B, Lee JT. X chromosome dosage compensation: how mammals keep the balance. Annu Rev Genet 2008; 42: 733-72.
-
(2008)
Annu Rev Genet
, vol.42
, pp. 733-772
-
-
Payer, B.1
Lee, J.T.2
-
7
-
-
85047700334
-
DNA methylation, imprinting and cancer
-
Plass C, Soloway PD. DNA methylation, imprinting and cancer. Eur J Hum Genet 2002; 10: 6-16.
-
(2002)
Eur J Hum Genet
, vol.10
, pp. 6-16
-
-
Plass, C.1
Soloway, P.D.2
-
8
-
-
0034713275
-
CTCF mediates methylation-sensitive enhancerblocking activity at the H19/Igf2 locus [see comments]
-
Hark AT, Schoenherr CJ, Katz DJ, Ingram RS, Levorse JM, Tilghman SM. CTCF mediates methylation-sensitive enhancerblocking activity at the H19/Igf2 locus [see comments]. Nature 2000; 405: 486-9.
-
(2000)
Nature
, vol.405
, pp. 486-489
-
-
Hark, A.T.1
Schoenherr, C.J.2
Katz, D.J.3
Ingram, R.S.4
Levorse, J.M.5
Tilghman, S.M.6
-
9
-
-
0036145567
-
Dynamic reprogramming of DNA methylation in the early mouse embryo
-
Santos F, Hendrich B, Reik W, Dean W. Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev Biol 2002; 241: 172-82.
-
(2002)
Dev Biol
, vol.241
, pp. 172-182
-
-
Santos, F.1
Hendrich, B.2
Reik, W.3
Dean, W.4
-
10
-
-
0032401808
-
Aging and DNA methylation in colorectal mucosa and cancer
-
Ahuja N, Li Q, Mohan AL, Baylin SB, Issa JP. Aging and DNA methylation in colorectal mucosa and cancer. Cancer Res 1998; 58: 5489-94.
-
(1998)
Cancer Res
, vol.58
, pp. 5489-5894
-
-
Ahuja, N.1
Li, Q.2
Mohan, A.L.3
Baylin, S.B.4
Issa, J.P.5
-
11
-
-
77649240380
-
Widespread and tissue specific age-related DNA methylation changes in mice
-
Maegawa S, Hinkal G, Kim HS, et al. Widespread and tissue specific age-related DNA methylation changes in mice. Genome Res 2010; 20: 332-40.
-
(2010)
Genome Res
, vol.20
, pp. 332-340
-
-
Maegawa, S.1
Hinkal, G.2
Kim, H.S.3
-
12
-
-
34249275353
-
Phenotypic plasticity and the epigenetics of human disease
-
Feinberg AP. Phenotypic plasticity and the epigenetics of human disease. Nature 2007; 447: 433-40.
-
(2007)
Nature
, vol.447
, pp. 433-440
-
-
Feinberg, A.P.1
-
13
-
-
33947611552
-
Nutri-epigenomics: Lifelong remodelling of our epigenomes by nutritional and metabolic factors and beyond
-
Gallou-Kabani C, Vige A, Gross MS, Junien C. Nutri-epigenomics: lifelong remodelling of our epigenomes by nutritional and metabolic factors and beyond. Clin Chem Lab Med 2007; 45: 321-7.
-
(2007)
Clin Chem Lab Med
, vol.45
, pp. 321-327
-
-
Gallou-Kabani, C.1
Vige, A.2
Gross, M.S.3
Junien, C.4
-
14
-
-
66149091609
-
The role of epigenetics in mediating environmental effects on phenotype
-
discussion 17-9, 259-68
-
Morgan DK, Whitelaw E. The role of epigenetics in mediating environmental effects on phenotype. Nestle Nutr Workshop Ser Pediatr Program 2009; 63: 109-17; discussion 17-9, 259-68.
-
(2009)
Nestle Nutr Workshop Ser Pediatr Program
, vol.63
, pp. 109-117
-
-
Morgan, D.K.1
Whitelaw, E.2
-
15
-
-
69349093211
-
Environmental influences on epigenetic profiles
-
Suter MA, Aagaard-Tillery KM. Environmental influences on epigenetic profiles. Semin Reprod Med 2009; 27: 380-90.
-
(2009)
Semin Reprod Med
, vol.27
, pp. 380-390
-
-
Suter, M.A.1
Aagaard-Tillery, K.M.2
-
16
-
-
25844488336
-
Aberrant DNA methylation in cutaneous malignancies
-
van Doorn R, Gruis NA, Willemze R, van der Velden PA, Tensen CP. Aberrant DNA methylation in cutaneous malignancies. Semin Oncol 2005; 32: 479-87.
-
(2005)
Semin Oncol
, vol.32
, pp. 479-487
-
-
van Doorn, R.1
Gruis, N.A.2
Willemze, R.3
van der Velden, P.A.4
Tensen, C.P.5
-
17
-
-
33947310031
-
Environmental epigenomics and disease susceptibility
-
Jirtle RL, Skinner MK. Environmental epigenomics and disease susceptibility. Nat Rev Genet 2007; 8: 253-62.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 253-262
-
-
Jirtle, R.L.1
Skinner, M.K.2
-
18
-
-
53349103842
-
Diet and the epigenetic (re)programming of phenotypic differences in behavior
-
McGowan PO, Meaney MJ, Szyf M. Diet and the epigenetic (re)programming of phenotypic differences in behavior. Brain Res 2008; 1237: 12-24.
-
(2008)
Brain Res
, vol.1237
, pp. 12-24
-
-
McGowan, P.O.1
Meaney, M.J.2
Szyf, M.3
-
19
-
-
0021101229
-
The 5- methylcytosine content of DNA from human tumors
-
Gama-Sosa MA, Slagel VA, Trewyn RW, et al. The 5- methylcytosine content of DNA from human tumors. Nucleic Acids Res 1983; 11: 6883-94.
-
(1983)
Nucleic Acids Res
, vol.11
, pp. 6883-6894
-
-
Gama-Sosa, M.A.1
Slagel, V.A.2
Trewyn, R.W.3
-
20
-
-
33748106693
-
Genome-wide analysis of DNA methylation changes in human malignancies
-
Plass C, Smiraglia DJ. Genome-wide analysis of DNA methylation changes in human malignancies. Curr Top Microbiol Immunol 2006; 310: 179-98.
-
(2006)
Curr Top Microbiol Immunol
, vol.310
, pp. 179-198
-
-
Plass, C.1
Smiraglia, D.J.2
-
21
-
-
0242584449
-
Induction of tumors in mice by genomic hypomethylation
-
Gaudet F, Hodgson JG, Eden A, et al. Induction of tumors in mice by genomic hypomethylation. Science 2003; 300: 489-92.
-
(2003)
Science
, vol.300
, pp. 489-492
-
-
Gaudet, F.1
Hodgson, J.G.2
Eden, A.3
-
22
-
-
0034176798
-
DNA hypermethylation in tumorigenesis: Epigenetics joins genetics
-
Baylin SB, Herman JG. DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 2000; 16: 168-74.
-
(2000)
Trends Genet
, vol.16
, pp. 168-174
-
-
Baylin, S.B.1
Herman, J.G.2
-
24
-
-
0037068360
-
DNA methylation and breast carcinogenesis
-
Widschwendter M, Jones PA. DNA methylation and breast carcinogenesis. Oncogene 2002; 21: 5462-82.
-
(2002)
Oncogene
, vol.21
, pp. 5462-5482
-
-
Widschwendter, M.1
Jones, P.A.2
-
25
-
-
8444220925
-
Molecular biomarker in prostate cancer: The role of CpG island hypermethylation
-
Bastian PJ, Yegnasubramanian S, Palapattu GS, et al. Molecular biomarker in prostate cancer: the role of CpG island hypermethylation. Eur Urol 2004; 46: 698-708.
-
(2004)
Eur Urol
, vol.46
, pp. 698-708
-
-
Bastian, P.J.1
Yegnasubramanian, S.2
Palapattu, G.S.3
-
26
-
-
43949091796
-
Lung cancer epigenetics and genetics
-
Risch A, Plass C. Lung cancer epigenetics and genetics. Int J Cancer 2008; 123: 1-7.
-
(2008)
Int J Cancer
, vol.123
, pp. 1-7
-
-
Risch, A.1
Plass, C.2
-
27
-
-
0343621494
-
Aberrant CpGisland methylation has non-random and tumour-type-specific patterns
-
Costello JF, Fruhwald MC, Smiraglia DJ, et al. Aberrant CpGisland methylation has non-random and tumour-type-specific patterns. Nat Genet 2000; 24: 132-38.
-
(2000)
Nat Genet
, vol.24
, pp. 132-138
-
-
Costello, J.F.1
Fruhwald, M.C.2
Smiraglia, D.J.3
-
28
-
-
0033047813
-
Methylation profiling of CpG islands in human breast cancer cells
-
Huang TH, Perry MR, Laux DE. Methylation profiling of CpG islands in human breast cancer cells. Hum Mol Genet 1999; 8: 459-70.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 459-470
-
-
Huang, T.H.1
Perry, M.R.2
Laux, D.E.3
-
29
-
-
33748055105
-
MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells
-
Rauch T, Li H, Wu X, Pfeifer GP. MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells. Cancer Res 2006; 66: 7939-47.
-
(2006)
Cancer Res
, vol.66
, pp. 7939-7947
-
-
Rauch, T.1
Li, H.2
Wu, X.3
Pfeifer, G.P.4
-
30
-
-
73649110641
-
DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia
-
Figueroa ME, Lugthart S, Li Y, et al. DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia. Cancer Cell 2010; 17: 13-27.
-
(2010)
Cancer Cell
, vol.17
, pp. 13-27
-
-
Figueroa, M.E.1
Lugthart, S.2
Li, Y.3
-
31
-
-
2442716565
-
Bone morphogenetic protein 3B silencing in non-small-cell lung cancer
-
Dai Z, Popkie AP, Zhu WG, et al. Bone morphogenetic protein 3B silencing in non-small-cell lung cancer. Oncogene 2004; 23: 3521-9.
-
(2004)
Oncogene
, vol.23
, pp. 3521-3529
-
-
Dai, Z.1
Popkie, A.P.2
Zhu, W.G.3
-
32
-
-
11144356462
-
Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets
-
Rush LJ, Raval A, Funchain P, et al. Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets. Cancer Res 2004; 64: 2424-33.
-
(2004)
Cancer Res
, vol.64
, pp. 2424-2433
-
-
Rush, L.J.1
Raval, A.2
Funchain, P.3
-
33
-
-
0035899347
-
Aberrant promoter methylation of previously unidentified target genes is a common abnormality in medulloblastomas--implications for tumor biology and potential clinical utility
-
Fruhwald MC, MS OD, Dai Z, et al. Aberrant promoter methylation of previously unidentified target genes is a common abnormality in medulloblastomas--implications for tumor biology and potential clinical utility. Oncogene 2001; 20: 5033-42.
-
(2001)
Oncogene
, vol.20
, pp. 5033-5042
-
-
Fruhwald, M.C.1
Ms, O.D.2
Dai, Z.3
-
35
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister R, Pelizzola M, Dowen RH, et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 2009; 462: 315-22.
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
-
36
-
-
66449121652
-
Finding the fifth base: Genome-wide sequencing of cytosine methylation
-
Lister R, Ecker JR. Finding the fifth base: genome-wide sequencing of cytosine methylation. Genome Res 2009; 19: 959-66.
-
(2009)
Genome Res
, vol.19
, pp. 959-966
-
-
Lister, R.1
Ecker, J.R.2
-
37
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides T. Chromatin modifications and their function. Cell 2007; 128: 693-705.
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
38
-
-
32544431582
-
Epigenetics and human disease: Translating basic biology into clinical applications
-
Rodenhiser D, Mann M. Epigenetics and human disease: translating basic biology into clinical applications. CMAJ 2006; 174: 341-8.
-
(2006)
CMAJ
, vol.174
, pp. 341-348
-
-
Rodenhiser, D.1
Mann, M.2
-
39
-
-
31544481927
-
Histone deacetylases as targets for dietary cancer preventive agents: Lessons learned with butyrate, diallyl disulfide, and sulforaphane
-
Myzak MC, Dashwood RH. Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane. Curr Drug Targets 2006; 7: 443-52.
-
(2006)
Curr Drug Targets
, vol.7
, pp. 443-452
-
-
Myzak, M.C.1
Dashwood, R.H.2
-
41
-
-
56249130451
-
Targeting epigenetic mechanisms: Potential of natural products in cancer chemoprevention
-
Hauser AT, Jung M. Targeting epigenetic mechanisms: potential of natural products in cancer chemoprevention. Planta Med 2008; 74: 1593-601.
-
(2008)
Planta Med
, vol.74
, pp. 1593-1601
-
-
Hauser, A.T.1
Jung, M.2
-
42
-
-
39749127166
-
The Rpd3/Hda1 family of lysine deacetylases: From bacteria and yeast to mice and men
-
Yang XJ, Seto E. The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men. Nat Rev Mol Cell Biol 2008; 9: 206-18.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 206-218
-
-
Yang, X.J.1
Seto, E.2
-
43
-
-
73949128107
-
Histone deacetylase inhibitors in cancer therapy
-
Lane AA, Chabner BA. Histone deacetylase inhibitors in cancer therapy. J Clin Oncol 2009; 27: 5459-68.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5459-5468
-
-
Lane, A.A.1
Chabner, B.A.2
-
44
-
-
0344640906
-
Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation
-
Haggarty SJ, Koeller KM, Wong JC, Grozinger CM, Schreiber SL. Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation. Proc Natl Acad Sci U S A 2003; 100: 4389-94.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 4389-4394
-
-
Haggarty, S.J.1
Koeller, K.M.2
Wong, J.C.3
Grozinger, C.M.4
Schreiber, S.L.5
-
45
-
-
1842578986
-
Molecular evolution of the histone deacetylase family: Functional implications of phylogenetic analysis
-
Gregoretti IV, Lee YM, Goodson HV. Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis. J Mol Biol 2004; 338: 17-31.
-
(2004)
J Mol Biol
, vol.338
, pp. 17-31
-
-
Gregoretti, I.V.1
Lee, Y.M.2
Goodson, H.V.3
-
46
-
-
69949095918
-
Histone lysine methylation in genomic imprinting
-
Ciccone DN, Chen T. Histone lysine methylation in genomic imprinting. Epigenetics 2009; 4: 216-20.
-
(2009)
Epigenetics
, vol.4
, pp. 216-220
-
-
Ciccone, D.N.1
Chen, T.2
-
47
-
-
9244252580
-
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
-
Huyen Y, Zgheib O, Ditullio RA, Jr., et al. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature 2004; 432: 406-11.
-
(2004)
Nature
, vol.432
, pp. 406-411
-
-
Huyen, Y.1
Zgheib, O.2
Ditullio Jr., R.A.3
-
48
-
-
23944509075
-
The SET-domain protein superfamily: Protein lysine methyltransferases
-
Dillon SC, Zhang X, Trievel RC, Cheng X. The SET-domain protein superfamily: protein lysine methyltransferases. Genome Biol 2005; 6: 227.
-
(2005)
Genome Biol
, vol.6
, pp. 227
-
-
Dillon, S.C.1
Zhang, X.2
Trievel, R.C.3
Cheng, X.4
-
49
-
-
58149151514
-
Controlling histone methylation via trans-histone pathways
-
Fingerman IM, Du HN, Briggs SD. Controlling histone methylation via trans-histone pathways. Epigenetics 2008; 3: 237-42.
-
(2008)
Epigenetics
, vol.3
, pp. 237-242
-
-
Fingerman, I.M.1
Du, H.N.2
Briggs, S.D.3
-
50
-
-
43249102851
-
Erasing the methyl mark: Histone demethylases at the center of cellular differentiation and disease
-
Cloos PA, Christensen J, Agger K, Helin K. Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease. Genes Dev 2008; 22: 1115-40.
-
(2008)
Genes Dev
, vol.22
, pp. 1115-1140
-
-
Cloos, P.A.1
Christensen, J.2
Agger, K.3
Helin, K.4
-
51
-
-
35349006314
-
Histone lysine demethylases: Emerging roles in development, physiology and disease
-
Shi Y. Histone lysine demethylases: emerging roles in development, physiology and disease. Nat Rev Genet 2007; 8: 829-33.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 829-833
-
-
Shi, Y.1
-
52
-
-
70349469565
-
Mechanisms of polycomb gene silencing: Knowns and unknowns
-
Simon JA, Kingston RE. Mechanisms of polycomb gene silencing: knowns and unknowns. Nat Rev Mol Cell Biol 2009; 10: 697-708.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 697-708
-
-
Simon, J.A.1
Kingston, R.E.2
-
53
-
-
70350500219
-
Polycomb group proteins: Navigators of lineage pathways led astray in cancer
-
Bracken AP, Helin K. Polycomb group proteins: navigators of lineage pathways led astray in cancer. Nat Rev Cancer 2009; 9: 773-84.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 773-784
-
-
Bracken, A.P.1
Helin, K.2
-
54
-
-
33947134834
-
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
-
Bracken AP, Kleine-Kohlbrecher D, Dietrich N, et al. The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells. Genes Dev 2007; 21: 525-30.
-
(2007)
Genes Dev
, vol.21
, pp. 525-530
-
-
Bracken, A.P.1
Kleine-Kohlbrecher, D.2
Dietrich, N.3
-
55
-
-
61849137222
-
Many roads to maturity: MicroRNA biogenesis pathways and their regulation
-
Winter J, Jung S, Keller S, Gregory RI, Diederichs S. Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat Cell Biol 2009; 11: 228-34.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 228-234
-
-
Winter, J.1
Jung, S.2
Keller, S.3
Gregory, R.I.4
Diederichs, S.5
-
56
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006; 6: 857-66.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
57
-
-
73849092036
-
MicroRNAs and cancer epigenetics: A macrorevolution
-
Davalos V, Esteller M. MicroRNAs and cancer epigenetics: a macrorevolution. Curr Opin Oncol 2010; 22: 35-45.
-
(2010)
Curr Opin Oncol
, vol.22
, pp. 35-45
-
-
Davalos, V.1
Esteller, M.2
-
58
-
-
77952918274
-
Genetic variation in microRNA networks: The implications for cancer research
-
Ryan BM, Robles AI, Harris CC. Genetic variation in microRNA networks: the implications for cancer research. Nat Rev Cancer 2010; 10: 389-402.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 389-402
-
-
Ryan, B.M.1
Robles, A.I.2
Harris, C.C.3
-
59
-
-
60549084170
-
MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium
-
Schembri F, Sridhar S, Perdomo C, et al. MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc Natl Acad Sci U S A 2009; 106: 2319-24.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 2319-2324
-
-
Schembri, F.1
Sridhar, S.2
Perdomo, C.3
-
60
-
-
0037455915
-
Epigenetic gene silencing in cancer initiation and progression
-
Nephew KP, Huang TH. Epigenetic gene silencing in cancer initiation and progression. Cancer Lett 2003; 190: 125-33.
-
(2003)
Cancer Lett
, vol.190
, pp. 125-133
-
-
Nephew, K.P.1
Huang, T.H.2
-
61
-
-
18144384816
-
Targeting epigenetic regulatory mechanisms in cancer chemoprevention
-
Fay JR, Crowell JA, Kopelovich L. Targeting epigenetic regulatory mechanisms in cancer chemoprevention. Expert Opin Ther Targets 2005; 9: 315-28.
-
(2005)
Expert Opin Ther Targets
, vol.9
, pp. 315-328
-
-
Fay, J.R.1
Crowell, J.A.2
Kopelovich, L.3
-
62
-
-
52449133362
-
Stage-specific alterations of DNA methyltransferase expression, DNA hypermethylation, and DNA hypomethylation during prostate cancer progression in the transgenic adenocarcinoma of mouse prostate model
-
Morey Kinney SR, Smiraglia DJ, James SR, Moser MT, Foster BA, Karpf AR. Stage-specific alterations of DNA methyltransferase expression, DNA hypermethylation, and DNA hypomethylation during prostate cancer progression in the transgenic adenocarcinoma of mouse prostate model. Mol Cancer Res 2008; 6: 1365-74.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 1365-1374
-
-
Morey Kinney, S.R.1
Smiraglia, D.J.2
James, S.R.3
Moser, M.T.4
Foster, B.A.5
Karpf, A.R.6
-
63
-
-
69449100327
-
Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia
-
Chen SS, Raval A, Johnson AJ, et al. Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia. Proc Natl Acad Sci USA 2009; 106: 13433-8.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 13433-13438
-
-
Chen, S.S.1
Raval, A.2
Johnson, A.J.3
-
64
-
-
84859450157
-
-
Corpet D. http://www.inra.fr/reseau-nacre/sci-memb/corpet/ indexan.html.
-
-
-
Corpet, D.1
-
65
-
-
0029001154
-
Suppression of intestinal neoplasia by DNA hypomethylation
-
Laird PW, Jackson-Grusby L, Fazeli A, et al. Suppression of intestinal neoplasia by DNA hypomethylation. Cell 1995; 81: 197-205.
-
(1995)
Cell
, vol.81
, pp. 197-205
-
-
Laird, P.W.1
Jackson-Grusby, L.2
Fazeli, A.3
-
66
-
-
61549106628
-
Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice
-
Yoo CB, Chuang JC, Byun HM, et al. Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice. Cancer Prev Res (Phila Pa) 2008; 1: 233-40.
-
(2008)
Cancer Prev Res (Phila Pa)
, vol.1
, pp. 233-240
-
-
Yoo, C.B.1
Chuang, J.C.2
Byun, H.M.3
-
67
-
-
0037357210
-
Diet and DNA methylation interactions in cancer prevention
-
Ross SA. Diet and DNA methylation interactions in cancer prevention. Ann N Y Acad Sci 2003; 983: 197-207.
-
(2003)
Ann N Y Acad Sci
, vol.983
, pp. 197-207
-
-
Ross, S.A.1
-
68
-
-
48349087987
-
Introduction: Diet, epigenetic events and cancer prevention
-
Ross SA, Dwyer J, Umar A, et al. Introduction: diet, epigenetic events and cancer prevention. Nutr Rev 2008; 66 Suppl 1: S1-6.
-
(2008)
Nutr Rev
, vol.66
, Issue.SUPPL. 1
-
-
Ross, S.A.1
Dwyer, J.2
Umar, A.3
-
70
-
-
39149091066
-
Environment, diet and CpG island methylation: Epigenetic signals in gastrointestinal neoplasia
-
Johnson IT, Belshaw NJ. Environment, diet and CpG island methylation: epigenetic signals in gastrointestinal neoplasia. Food Chem Toxicol 2008; 46: 1346-59.
-
(2008)
Food Chem Toxicol
, vol.46
, pp. 1346-1359
-
-
Johnson, I.T.1
Belshaw, N.J.2
-
71
-
-
54949104629
-
A review of dietary factors and its influence on DNA methylation in colorectal carcinogenesis
-
Arasaradnam RP, Commane DM, Bradburn D, Mathers JC. A review of dietary factors and its influence on DNA methylation in colorectal carcinogenesis. Epigenetics 2008; 3: 193-8.
-
(2008)
Epigenetics
, vol.3
, pp. 193-198
-
-
Arasaradnam, R.P.1
Commane, D.M.2
Bradburn, D.3
Mathers, J.C.4
-
72
-
-
70350070121
-
Genetic and epigenetic regulations of prostate cancer by genistein
-
Molinie B, Georgel P. Genetic and epigenetic regulations of prostate cancer by genistein. Drug News Perspect 2009; 22: 247-54.
-
(2009)
Drug News Perspect
, vol.22
, pp. 247-254
-
-
Molinie, B.1
Georgel, P.2
-
74
-
-
77953506826
-
Flavonoids influence epigenetic-modifying enzyme activity: Structure - function relationships and the therapeutic potential for cancer
-
Gilbert ER, Liu D. Flavonoids influence epigenetic-modifying enzyme activity: structure - function relationships and the therapeutic potential for cancer. Curr Med Chem 2010; 17: 1756-68.
-
(2010)
Curr Med Chem
, vol.17
, pp. 1756-1768
-
-
Gilbert, E.R.1
Liu, D.2
-
75
-
-
77955621544
-
Impact on DNA Methylation in Cancer Prevention and Therapy by Bioactive Dietary Components
-
Li Y, Tollefsbol TO. Impact on DNA Methylation in Cancer Prevention and Therapy by Bioactive Dietary Components. Curr Med Chem 2010; 17: 2141-51.
-
(2010)
Curr Med Chem
, vol.17
, pp. 2141-2151
-
-
Li, Y.1
Tollefsbol, T.O.2
-
76
-
-
48349133693
-
Evidence for dietary regulation of microRNA expression in cancer cells
-
Davis CD, Ross SA. Evidence for dietary regulation of microRNA expression in cancer cells. Nutr Rev 2008; 66: 477-82.
-
(2008)
Nutr Rev
, vol.66
, pp. 477-482
-
-
Davis, C.D.1
Ross, S.A.2
-
78
-
-
77953198124
-
Regulation of microRNAs by natural agents: An emerging field in chemoprevention and chemotherapy research
-
Li Y, Kong D, Wang Z, Sarkar FH. Regulation of microRNAs by natural agents: an emerging field in chemoprevention and chemotherapy research. Pharm Res 2010; 27: 1027-41.
-
(2010)
Pharm Res
, vol.27
, pp. 1027-1041
-
-
Li, Y.1
Kong, D.2
Wang, Z.3
Sarkar, F.H.4
-
79
-
-
78349269863
-
Development of curcumin as an epigenetic agent
-
Fu S, Kurzrock R. Development of curcumin as an epigenetic agent. Cancer 2010; 116: 4670-6.
-
(2010)
Cancer
, vol.116
, pp. 4670-4676
-
-
Fu, S.1
Kurzrock, R.2
-
80
-
-
0036593394
-
Histone methyltransferases, diet nutrients and tumour suppressors
-
Huang S. Histone methyltransferases, diet nutrients and tumour suppressors. Nat Rev Cancer 2002; 2: 469-76.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 469-476
-
-
Huang, S.1
-
81
-
-
0041383927
-
Chemoprevention of colon cancer by calcium, vitamin D and folate: Molecular mechanisms
-
Lamprecht SA, Lipkin M. Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanisms. Nat Rev Cancer 2003; 3: 601-14.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 601-614
-
-
Lamprecht, S.A.1
Lipkin, M.2
-
82
-
-
79952140468
-
Folate and cancer: How DNA damage, repair and methylation impact on colon carcinogenesis
-
Duthie SJ. Folate and cancer: how DNA damage, repair and methylation impact on colon carcinogenesis. J Inherit Metab Dis 2011; 34: 101-9.
-
(2011)
J Inherit Metab Dis
, vol.34
, pp. 101-109
-
-
Duthie, S.J.1
-
83
-
-
3242764554
-
Folate, colorectal carcinogenesis, and DNA methylation: Lessons from animal studies
-
Kim YI. Folate, colorectal carcinogenesis, and DNA methylation: lessons from animal studies. Environ Mol Mutagen 2004; 44: 10-25.
-
(2004)
Environ Mol Mutagen
, vol.44
, pp. 10-25
-
-
Kim, Y.I.1
-
84
-
-
31544467532
-
Nutritional epigenetics: Impact of folate deficiency on DNA methylation and colon cancer susceptibility
-
Kim YI. Nutritional epigenetics: impact of folate deficiency on DNA methylation and colon cancer susceptibility. J Nutr 2005; 135: 2703-9.
-
(2005)
J Nutr
, vol.135
, pp. 2703-2709
-
-
Kim, Y.I.1
-
85
-
-
76549092462
-
Multivitamins, folate, and green vegetables protect against gene promoter methylation in the aerodigestive tract of smokers
-
Stidley CA, Picchi MA, Leng S, et al. Multivitamins, folate, and green vegetables protect against gene promoter methylation in the aerodigestive tract of smokers. Cancer Res 2010; 70: 568-74.
-
(2010)
Cancer Res
, vol.70
, pp. 568-574
-
-
Stidley, C.A.1
Picchi, M.A.2
Leng, S.3
-
86
-
-
33749479908
-
Downregulation of miR-122 in the rodent and human hepatocellular carcinomas
-
Kutay H, Bai S, Datta J, et al. Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. J Cell Biochem 2006; 99: 671-8.
-
(2006)
J Cell Biochem
, vol.99
, pp. 671-678
-
-
Kutay, H.1
Bai, S.2
Datta, J.3
-
87
-
-
33845312687
-
MicroRNA responses to cellular stress
-
Marsit CJ, Eddy K, Kelsey KT. MicroRNA responses to cellular stress. Cancer Res 2006; 66: 10843-8.
-
(2006)
Cancer Res
, vol.66
, pp. 10843-10848
-
-
Marsit, C.J.1
Eddy, K.2
Kelsey, K.T.3
-
88
-
-
28244462778
-
Selenium in cancer prevention: A review of the evidence and mechanism of action
-
Rayman MP. Selenium in cancer prevention: a review of the evidence and mechanism of action. Proc Nutr Soc 2005; 64: 527-42.
-
(2005)
Proc Nutr Soc
, vol.64
, pp. 527-542
-
-
Rayman, M.P.1
-
89
-
-
0345310068
-
Chemopreventive agents: Selenium
-
Combs GF, Jr., Gray WP. Chemopreventive agents: selenium. Pharmacol Ther 1998; 79: 179-92.
-
(1998)
Pharmacol Ther
, vol.79
, pp. 179-192
-
-
Combs Jr., G.F.1
Gray, W.P.2
-
90
-
-
58149383852
-
Effect of selenium and vitamin E On Risk of Prostate Cancer and Other Cancers: The Selenium and Vitamin E Cancer Prevention Trial (SELECT)
-
Lippman SM, Klein EA, Goodman PJ, et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 2009; 301: 39-51.
-
(2009)
JAMA
, vol.301
, pp. 39-51
-
-
Lippman, S.M.1
Klein, E.A.2
Goodman, P.J.3
-
91
-
-
77951140241
-
Current issues of selenium in cancer chemoprevention
-
Jung HJ, Seo YR. Current issues of selenium in cancer chemoprevention. Biofactors 2010; 36: 153-8.
-
(2010)
Biofactors
, vol.36
, pp. 153-158
-
-
Jung, H.J.1
Seo, Y.R.2
-
92
-
-
0031869119
-
Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation
-
Fiala ES, Staretz ME, Pandya GA, El-Bayoumy K, Hamilton SR. Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation. Carcinogenesis 1998; 19: 597-604.
-
(1998)
Carcinogenesis
, vol.19
, pp. 597-604
-
-
Fiala, E.S.1
Staretz, M.E.2
Pandya, G.A.3
El-Bayoumy, K.4
Hamilton, S.R.5
-
93
-
-
0034533186
-
Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells and in vivo in rat liver and colon
-
Davis CD, Uthus EO, Finley JW. Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells and in vivo in rat liver and colon. J Nutr 2000; 130: 2903-9.
-
(2000)
J Nutr
, vol.130
, pp. 2903-2909
-
-
Davis, C.D.1
Uthus, E.O.2
Finley, J.W.3
-
94
-
-
0036170179
-
Dietary selenite and azadeoxycytidine treatments affect dimethylhydrazine-induced aberrant crypt formation in rat colon and DNA methylation in HT-29 cells
-
Davis CD, Uthus EO. Dietary selenite and azadeoxycytidine treatments affect dimethylhydrazine-induced aberrant crypt formation in rat colon and DNA methylation in HT-29 cells. J Nutr 2002; 132: 292-7.
-
(2002)
J Nutr
, vol.132
, pp. 292-297
-
-
Davis, C.D.1
Uthus, E.O.2
-
95
-
-
0041417403
-
Dietary folate and selenium affect dimethylhydrazine-induced aberrant crypt formation, global DNA methylation and one-carbon metabolism in rats
-
Davis CD, Uthus EO. Dietary folate and selenium affect dimethylhydrazine-induced aberrant crypt formation, global DNA methylation and one-carbon metabolism in rats. J Nutr 2003; 133: 2907-14.
-
(2003)
J Nutr
, vol.133
, pp. 2907-2914
-
-
Davis, C.D.1
Uthus, E.O.2
-
96
-
-
56049083256
-
Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells
-
Xiang N, Zhao R, Song G, Zhong W. Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells. Carcinogenesis 2008; 29: 2175-81.
-
(2008)
Carcinogenesis
, vol.29
, pp. 2175-2181
-
-
Xiang, N.1
Zhao, R.2
Song, G.3
Zhong, W.4
-
97
-
-
77951525636
-
Selenite triggers rapid transcriptional activation of p53, and p53-mediated apoptosis in prostate cancer cells: Implication for the treatment of early-stage prostate cancer
-
Sarveswaran S, Liroff J, Zhou Z, Nikitin AY, Ghosh J. Selenite triggers rapid transcriptional activation of p53, and p53-mediated apoptosis in prostate cancer cells: Implication for the treatment of early-stage prostate cancer. Int J Oncol 2010; 36: 1419-28.
-
(2010)
Int J Oncol
, vol.36
, pp. 1419-1428
-
-
Sarveswaran, S.1
Liroff, J.2
Zhou, Z.3
Nikitin, A.Y.4
Ghosh, J.5
-
98
-
-
74249123570
-
The miR-34 family in cancer and apoptosis
-
Hermeking H. The miR-34 family in cancer and apoptosis. Cell Death Differ 2010; 17: 193-9.
-
(2010)
Cell Death Differ
, vol.17
, pp. 193-199
-
-
Hermeking, H.1
-
99
-
-
69449083759
-
Alpha-keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells
-
Nian H, Bisson WH, Dashwood WM, Pinto JT, Dashwood RH. Alpha-keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells. Carcinogenesis 2009; 30: 1416-23.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1416-1423
-
-
Nian, H.1
Bisson, W.H.2
Dashwood, W.M.3
Pinto, J.T.4
Dashwood, R.H.5
-
100
-
-
34548379910
-
Biomarker and animal models for assessment of retinoid efficacy in cancer chemoprevention
-
Niles RM. Biomarker and animal models for assessment of retinoid efficacy in cancer chemoprevention. Acta Pharmacol Sin 2007; 28: 1383-91.
-
(2007)
Acta Pharmacol Sin
, vol.28
, pp. 1383-1391
-
-
Niles, R.M.1
-
101
-
-
58149192652
-
Retinoids, rexinoids and their cognate nuclear receptors: Character and their role in chemoprevention of selected malignant diseases
-
Brtko J. Retinoids, rexinoids and their cognate nuclear receptors: character and their role in chemoprevention of selected malignant diseases. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2007; 151: 187-94.
-
(2007)
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
, vol.151
, pp. 187-194
-
-
Brtko, J.1
-
102
-
-
0036142502
-
Retinoids and their receptors in cancer development and chemoprevention
-
Sun SY, Lotan R. Retinoids and their receptors in cancer development and chemoprevention. Crit Rev Oncol Hematol 2002; 41: 41-55.
-
(2002)
Crit Rev Oncol Hematol
, vol.41
, pp. 41-55
-
-
Sun, S.Y.1
Lotan, R.2
-
103
-
-
0035749803
-
The promise of retinoids to fight against cancer
-
Altucci L, Gronemeyer H. The promise of retinoids to fight against cancer. Nat Rev Cancer 2001; 1: 181-93.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 181-193
-
-
Altucci, L.1
Gronemeyer, H.2
-
104
-
-
50949132079
-
Dietary manipulation of histone structure and function
-
Delage B, Dashwood RH. Dietary manipulation of histone structure and function. Annu Rev Nutr 2008; 28: 347-66.
-
(2008)
Annu Rev Nutr
, vol.28
, pp. 347-366
-
-
Delage, B.1
Dashwood, R.H.2
-
105
-
-
0242624636
-
Epigenetic targets in hematopoietic malignancies
-
Claus R, Lubbert M. Epigenetic targets in hematopoietic malignancies. Oncogene 2003; 22: 6489-96.
-
(2003)
Oncogene
, vol.22
, pp. 6489-6496
-
-
Claus, R.1
Lubbert, M.2
-
106
-
-
34249331209
-
MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia
-
Garzon R, Pichiorri F, Palumbo T, et al. MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia. Oncogene 2007; 26: 4148-57.
-
(2007)
Oncogene
, vol.26
, pp. 4148-4157
-
-
Garzon, R.1
Pichiorri, F.2
Palumbo, T.3
-
107
-
-
77949906655
-
Non-coding RNAs change their expression profile after Retinoid induced differentiation of the promyelocytic cell line NB4
-
Rossi A, D'Urso OF, Gatto G, et al. Non-coding RNAs change their expression profile after Retinoid induced differentiation of the promyelocytic cell line NB4. BMC Res Notes 2010; 3: 24.
-
(2010)
BMC Res Notes
, vol.3
, pp. 24
-
-
Rossi, A.1
D'Urso, O.F.2
Gatto, G.3
-
108
-
-
0036558155
-
Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer
-
Sirchia SM, Ren M, Pili R, et al. Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer. Cancer Res 2002; 62: 2455-61.
-
(2002)
Cancer Res
, vol.62
, pp. 2455-2461
-
-
Sirchia, S.M.1
Ren, M.2
Pili, R.3
-
109
-
-
0038527642
-
Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor
-
Di Croce L, Raker VA, Corsaro M, et al. Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 2002; 295: 1079-82.
-
(2002)
Science
, vol.295
, pp. 1079-1082
-
-
Di Croce, L.1
Raker, V.A.2
Corsaro, M.3
-
110
-
-
10044243603
-
Epigenomic changes during leukemia cell differentiation: Analysis of histone acetylation and cytosine methylation using CpG island microarrays
-
Nouzova M, Holtan N, Oshiro MM, et al. Epigenomic changes during leukemia cell differentiation: analysis of histone acetylation and cytosine methylation using CpG island microarrays. J Pharmacol Exp Ther 2004; 311: 968-81.
-
(2004)
J Pharmacol Exp Ther
, vol.311
, pp. 968-981
-
-
Nouzova, M.1
Holtan, N.2
Oshiro, M.M.3
-
111
-
-
3342913667
-
Epigenetic regulation of human telomerase reverse transcriptase promoter activity during cellular differentiation
-
Liu L, Saldanha SN, Pate MS, Andrews LG, Tollefsbol TO. Epigenetic regulation of human telomerase reverse transcriptase promoter activity during cellular differentiation. Genes Chromosomes Cancer 2004; 41: 26-37.
-
(2004)
Genes Chromosomes Cancer
, vol.41
, pp. 26-37
-
-
Liu, L.1
Saldanha, S.N.2
Pate, M.S.3
Andrews, L.G.4
Tollefsbol, T.O.5
-
112
-
-
75149127233
-
Retinoid-induced histone deacetylation inhibits telomerase activity in estrogen receptor-negative breast cancer cells
-
Phipps SM, Love WK, White T, Andrews LG, Tollefsbol TO. Retinoid-induced histone deacetylation inhibits telomerase activity in estrogen receptor-negative breast cancer cells. Anticancer Res 2009; 29: 4959-64.
-
(2009)
Anticancer Res
, vol.29
, pp. 4959-4964
-
-
Phipps, S.M.1
Love, W.K.2
White, T.3
Andrews, L.G.4
Tollefsbol, T.O.5
-
113
-
-
63449129708
-
Differential expression of epigenetic modulators during human embryonic stem cell differentiation
-
Phipps SM, Love WK, Mott TE, Andrews LG, Tollefsbol TO. Differential expression of epigenetic modulators during human embryonic stem cell differentiation. Mol Biotechnol 2009; 41: 201-7.
-
(2009)
Mol Biotechnol
, vol.41
, pp. 201-207
-
-
Phipps, S.M.1
Love, W.K.2
Mott, T.E.3
Andrews, L.G.4
Tollefsbol, T.O.5
-
114
-
-
76549130531
-
A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide
-
Tang XH, Albert M, Scognamiglio T, Gudas LJ. A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide. Cancer Prev Res (Phila Pa) 2009; 2: 1100-10.
-
(2009)
Cancer Prev Res (Phila Pa)
, vol.2
, pp. 1100-1110
-
-
Tang, X.H.1
Albert, M.2
Scognamiglio, T.3
Gudas, L.J.4
-
115
-
-
77950874457
-
Cancer-preventive activities of tocopherols and tocotrienols
-
Ju J, Picinich SC, Yang Z, et al. Cancer-preventive activities of tocopherols and tocotrienols. Carcinogenesis 2010; 31: 533-42.
-
(2010)
Carcinogenesis
, vol.31
, pp. 533-542
-
-
Ju, J.1
Picinich, S.C.2
Yang, Z.3
-
116
-
-
51349168072
-
Multitargeted therapy of cancer by tocotrienols
-
Nesaretnam K. Multitargeted therapy of cancer by tocotrienols. Cancer Lett 2008; 269: 388-95.
-
(2008)
Cancer Lett
, vol.269
, pp. 388-395
-
-
Nesaretnam, K.1
-
117
-
-
53049092870
-
Vitamin E Dependent MicroRNA Regulation in Rat Liver
-
Gaedicke S, Zhang X, Schmelzer C, et al. Vitamin E dependent microRNA regulation in rat liver. FEBS Lett 2008; 582: 3542-6.
-
(2008)
FEBS Lett
, vol.582
, pp. 3542-3546
-
-
Gaedicke, S.1
Zhang, X.2
Schmelzer, C.3
-
118
-
-
77957916110
-
Dietary vitamin E deficiency does not affect global and specific DNA methylation patterns in rat liver
-
Fischer A, Gaedicke S, Frank J, Doring F, Rimbach G. Dietary vitamin E deficiency does not affect global and specific DNA methylation patterns in rat liver. Br J Nutr 2010; 104: 935-40.
-
(2010)
Br J Nutr
, vol.104
, pp. 935-940
-
-
Fischer, A.1
Gaedicke, S.2
Frank, J.3
Doring, F.4
Rimbach, G.5
-
120
-
-
37149022209
-
Review article: The role of butyrate on colonic function
-
Hamer HM, Jonkers D, Venema K, Vanhoutvin S, Troost FJ, Brummer RJ. Review article: the role of butyrate on colonic function. Aliment Pharmacol Ther 2008; 27: 104-19.
-
(2008)
Aliment Pharmacol Ther
, vol.27
, pp. 104-119
-
-
Hamer, H.M.1
Jonkers, D.2
Venema, K.3
Vanhoutvin, S.4
Troost, F.J.5
Brummer, R.J.6
-
121
-
-
0942301264
-
Microbial degradation products influence colon cancer risk: The butyrate controversy
-
Lupton JR. Microbial degradation products influence colon cancer risk: the butyrate controversy. J Nutr 2004; 134: 479-82.
-
(2004)
J Nutr
, vol.134
, pp. 479-482
-
-
Lupton, J.R.1
-
122
-
-
0017767153
-
n-Butyrate causes histone modification in HeLa and Friend erythroleukaemia cells
-
Riggs MG, Whittaker RG, Neumann JR, Ingram VM. n-Butyrate causes histone modification in HeLa and Friend erythroleukaemia cells. Nature 1977; 268: 462-4.
-
(1977)
Nature
, vol.268
, pp. 462-464
-
-
Riggs, M.G.1
Whittaker, R.G.2
Neumann, J.R.3
Ingram, V.M.4
-
123
-
-
0017886958
-
Sodium butyrate inhibits histone deacetylation in cultured cells
-
Candido EP, Reeves R, Davie JR. Sodium butyrate inhibits histone deacetylation in cultured cells. Cell 1978; 14: 105-13.
-
(1978)
Cell
, vol.14
, pp. 105-113
-
-
Candido, E.P.1
Reeves, R.2
Davie, J.R.3
-
124
-
-
0017864644
-
The effect of sodium butyrate on histone modification
-
Sealy L, Chalkley R. The effect of sodium butyrate on histone modification. Cell 1978; 14: 115-21.
-
(1978)
Cell
, vol.14
, pp. 115-121
-
-
Sealy, L.1
Chalkley, R.2
-
125
-
-
51849099492
-
The short chain fatty acid butyrate induces promoter demethylation and reactivation of RARbeta2 in colon cancer cells
-
Spurling CC, Suhl JA, Boucher N, Nelson CE, Rosenberg DW, Giardina C. The short chain fatty acid butyrate induces promoter demethylation and reactivation of RARbeta2 in colon cancer cells. Nutr Cancer 2008; 60: 692-702.
-
(2008)
Nutr Cancer
, vol.60
, pp. 692-702
-
-
Spurling, C.C.1
Suhl, J.A.2
Boucher, N.3
Nelson, C.E.4
Rosenberg, D.W.5
Giardina, C.6
-
126
-
-
70349570169
-
A human, doubleblind, placebo-controlled, crossover trial of prebiotic, probiotic, and synbiotic supplementation: Effects on luminal, inflammatory, epigenetic, and epithelial biomarkers of colorectal cancer
-
Worthley DL, Le Leu RK, Whitehall VL, et al. A human, doubleblind, placebo-controlled, crossover trial of prebiotic, probiotic, and synbiotic supplementation: effects on luminal, inflammatory, epigenetic, and epithelial biomarkers of colorectal cancer. Am J Clin Nutr 2009; 90: 578-86.
-
(2009)
Am J Clin Nutr
, vol.90
, pp. 578-586
-
-
Worthley, D.L.1
Le Leu, R.K.2
Whitehall, V.L.3
-
127
-
-
52649132486
-
MicroRNA differential expression profile during differentiation of embryonic stem cells towards hepatocytes induced by sodium butyrate
-
Chen YJ, Min J, Shang CZ, et al. [MicroRNA differential expression profile during differentiation of embryonic stem cells towards hepatocytes induced by sodium butyrate]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2008; 30: 469-73.
-
(2008)
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
, vol.30
, pp. 469-473
-
-
Chen, Y.J.1
Min, J.2
Shang, C.Z.3
-
128
-
-
67649449180
-
Cancer prevention by tea: Animal studies, molecular mechanisms and human relevance
-
Yang CS, Wang X, Lu G, Picinich SC. Cancer prevention by tea: animal studies, molecular mechanisms and human relevance. Nat Rev Cancer 2009; 9: 429-39.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 429-439
-
-
Yang, C.S.1
Wang, X.2
Lu, G.3
Picinich, S.C.4
-
129
-
-
0345275879
-
Tea polyphenol (-)- epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines
-
Fang MZ, Wang Y, Ai N, et al. Tea polyphenol (-)- epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res 2003; 63: 7563-70.
-
(2003)
Cancer Res
, vol.63
, pp. 7563-7570
-
-
Fang, M.Z.1
Wang, Y.2
Ai, N.3
-
130
-
-
25144507259
-
Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids
-
Lee WJ, Shim JY, Zhu BT. Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids. Mol Pharmacol 2005; 68: 1018-30.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 1018-1030
-
-
Lee, W.J.1
Shim, J.Y.2
Zhu, B.T.3
-
131
-
-
77955608756
-
Promoter demethylation and chromatin remodeling by green tea polyphenols leads to reexpression of GSTP1 in human prostate cancer cells
-
Pandey M, Shukla S, Gupta S. Promoter demethylation and chromatin remodeling by green tea polyphenols leads to reexpression of GSTP1 in human prostate cancer cells. Int J Cancer 2009.
-
(2009)
Int J Cancer
-
-
Pandey, M.1
Shukla, S.2
Gupta, S.3
-
132
-
-
31544441371
-
Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols
-
Lee WJ, Zhu BT. Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols. Carcinogenesis 2006; 27: 269-77.
-
(2006)
Carcinogenesis
, vol.27
, pp. 269-277
-
-
Lee, W.J.1
Zhu, B.T.2
-
133
-
-
33845969839
-
Dietary polyphenols may affect DNA methylation
-
Fang M, Chen D, Yang CS. Dietary polyphenols may affect DNA methylation. J Nutr 2007; 137: 223S-28S.
-
(2007)
J Nutr
, vol.137
-
-
Fang, M.1
Chen, D.2
Yang, C.S.3
-
134
-
-
38649100332
-
Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG
-
Berletch JB, Liu C, Love WK, Andrews LG, Katiyar SK, Tollefsbol TO. Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG. J Cell Biochem 2008; 103: 509-19.
-
(2008)
J Cell Biochem
, vol.103
, pp. 509-519
-
-
Berletch, J.B.1
Liu, C.2
Love, W.K.3
Andrews, L.G.4
Katiyar, S.K.5
Tollefsbol, T.O.6
-
135
-
-
49549087270
-
Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells
-
Kato K, Long NK, Makita H, et al. Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells. Br J Cancer 2008; 99: 647-54.
-
(2008)
Br J Cancer
, vol.99
, pp. 647-654
-
-
Kato, K.1
Long, N.K.2
Makita, H.3
-
136
-
-
67650892068
-
Promoter demethylation of WIF-1 by epigallocatechin-3-gallate in lung cancer cells
-
Gao Z, Xu Z, Hung MS, et al. Promoter demethylation of WIF-1 by epigallocatechin-3-gallate in lung cancer cells. Anticancer Res 2009; 29: 2025-30.
-
(2009)
Anticancer Res
, vol.29
, pp. 2025-2030
-
-
Gao, Z.1
Xu, Z.2
Hung, M.S.3
-
137
-
-
33751530490
-
Mining the Wnt pathway for cancer therapeutics
-
Barker N, Clevers H. Mining the Wnt pathway for cancer therapeutics. Nat Rev Drug Discov 2006; 5: 997-1014.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 997-1014
-
-
Barker, N.1
Clevers, H.2
-
138
-
-
27644597195
-
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5- aza-2'-deoxycytidine
-
Chuang JC, Yoo CB, Kwan JM, et al. Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5- aza-2'-deoxycytidine. Mol Cancer Ther 2005; 4: 1515-20.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1515-1520
-
-
Chuang, J.C.1
Yoo, C.B.2
Kwan, J.M.3
-
139
-
-
33645086120
-
Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines
-
Stresemann C, Brueckner B, Musch T, Stopper H, Lyko F. Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines. Cancer Res 2006; 66: 2794-800.
-
(2006)
Cancer Res
, vol.66
, pp. 2794-2800
-
-
Stresemann, C.1
Brueckner, B.2
Musch, T.3
Stopper, H.4
Lyko, F.5
-
140
-
-
37149017725
-
Annurca apple polyphenols have potent demethylating activity and can reactivate silenced tumor suppressor genes in colorectal cancer cells
-
Fini L, Selgrad M, Fogliano V, et al. Annurca apple polyphenols have potent demethylating activity and can reactivate silenced tumor suppressor genes in colorectal cancer cells. J Nutr 2007; 137: 2622-8.
-
(2007)
J Nutr
, vol.137
, pp. 2622-2628
-
-
Fini, L.1
Selgrad, M.2
Fogliano, V.3
-
141
-
-
56249137618
-
Cancer chemopreventive potential of apples, apple juice, and apple components
-
Gerhauser C. Cancer chemopreventive potential of apples, apple juice, and apple components. Planta Med 2008; 74: 1608-24.
-
(2008)
Planta Med
, vol.74
, pp. 1608-1624
-
-
Gerhauser, C.1
-
142
-
-
70349975929
-
Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer
-
Volate SR, Muga SJ, Issa AY, Nitcheva D, Smith T, Wargovich MJ. Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer. Mol Carcinog 2009; 48: 920-33.
-
(2009)
Mol Carcinog
, vol.48
, pp. 920-933
-
-
Volate, S.R.1
Muga, S.J.2
Issa, A.Y.3
Nitcheva, D.4
Smith, T.5
Wargovich, M.J.6
-
143
-
-
0035964175
-
Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols
-
Gupta S, Hastak K, Ahmad N, Lewin JS, Mukhtar H. Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols. Proc Natl Acad Sci U S A 2001; 98: 10350-5.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10350-10355
-
-
Gupta, S.1
Hastak, K.2
Ahmad, N.3
Lewin, J.S.4
Mukhtar, H.5
-
144
-
-
8844264520
-
The chemopreventive action of catechins in the TRAMP mouse model of prostate carcinogenesis is accompanied by clusterin over-expression
-
Caporali A, Davalli P, Astancolle S, et al. The chemopreventive action of catechins in the TRAMP mouse model of prostate carcinogenesis is accompanied by clusterin over-expression. Carcinogenesis 2004; 25: 2217-24.
-
(2004)
Carcinogenesis
, vol.25
, pp. 2217-2224
-
-
Caporali, A.1
Davalli, P.2
Astancolle, S.3
-
145
-
-
63549136229
-
Effective prostate cancer chemopreventive intervention with green tea polyphenols in the TRAMP model depends on the stage of the disease
-
Adhami VM, Siddiqui IA, Sarfaraz S, et al. Effective prostate cancer chemopreventive intervention with green tea polyphenols in the TRAMP model depends on the stage of the disease. Clin Cancer Res 2009; 15: 1947-53.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1947-1953
-
-
Adhami, V.M.1
Siddiqui, I.A.2
Sarfaraz, S.3
-
146
-
-
64249158774
-
DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients
-
Yuasa Y, Nagasaki H, Akiyama Y, et al. DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients. Int J Cancer 2009; 124: 2677-82.
-
(2009)
Int J Cancer
, vol.124
, pp. 2677-2682
-
-
Yuasa, Y.1
Nagasaki, H.2
Akiyama, Y.3
-
147
-
-
77950907191
-
The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival
-
Balasubramanian S, Adhikary G, Eckert RL. The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival. Carcinogenesis 2010; 31: 496-503.
-
(2010)
Carcinogenesis
, vol.31
, pp. 496-503
-
-
Balasubramanian, S.1
Adhikary, G.2
Eckert, R.L.3
-
148
-
-
73949133652
-
Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells
-
Tsang WP, Kwok TT. Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells. J Nutr Biochem 2010; 21: 140-6.
-
(2010)
J Nutr Biochem
, vol.21
, pp. 140-146
-
-
Tsang, W.P.1
Kwok, T.T.2
-
149
-
-
55949134303
-
DNA methylomes, histone codes and miRNAs: Tying it all together
-
Guil S, Esteller M. DNA methylomes, histone codes and miRNAs: tying it all together. Int J Biochem Cell Biol 2009; 41: 87-95.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 87-95
-
-
Guil, S.1
Esteller, M.2
-
150
-
-
33748988463
-
Addressing the soy and breast cancer relationship: Review, commentary, and workshop proceedings
-
Messina M, McCaskill-Stevens W, Lampe JW. Addressing the soy and breast cancer relationship: review, commentary, and workshop proceedings. J Natl Cancer Inst 2006; 98: 1275-84.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1275-1284
-
-
Messina, M.1
McCaskill-Stevens, W.2
Lampe, J.W.3
-
151
-
-
60849134580
-
Isoflavones, and prostate cancer
-
Jian L. Soy, isoflavones, and prostate cancer. Mol Nutr Food Res 2009; 53: 217-26.
-
(2009)
Mol Nutr Food Res
, vol.53
, pp. 217-226
-
-
Soy, J.L.1
-
152
-
-
52949095784
-
Isoflavones and the prevention of breast and prostate cancer: New perspectives opened by nutrigenomics
-
[Steiner C, Arnould S, Scalbert A, Manach C. Isoflavones and the prevention of breast and prostate cancer: new perspectives opened by nutrigenomics. Br J Nutr 2008; 99 E Suppl 1: ES78-108.
-
(2008)
Br J Nutr
, vol.99 E
, Issue.SUPPL. 1
-
-
Steiner, C.1
Arnould, S.2
Scalbert, A.3
Manach, C.4
-
155
-
-
70349573116
-
The effect of genistein aglycone on cancer and cancer risk: A review of in vitro, preclinical, and clinical studies
-
Taylor CK, Levy RM, Elliott JC, Burnett BP. The effect of genistein aglycone on cancer and cancer risk: a review of in vitro, preclinical, and clinical studies. Nutr Rev 2009; 67: 398-415.
-
(2009)
Nutr Rev
, vol.67
, pp. 398-415
-
-
Taylor, C.K.1
Levy, R.M.2
Elliott, J.C.3
Burnett, B.P.4
-
156
-
-
43249085452
-
The role of early life genistein exposures in modifying breast cancer risk
-
Warri A, Saarinen NM, Makela S, Hilakivi-Clarke L. The role of early life genistein exposures in modifying breast cancer risk. Br J Cancer 2008; 98: 1485-93.
-
(2008)
Br J Cancer
, vol.98
, pp. 1485-1493
-
-
Warri, A.1
Saarinen, N.M.2
Makela, S.3
Hilakivi-Clarke, L.4
-
157
-
-
34547558889
-
Nutritional modulation of terminal end buds: Its relevance to breast cancer prevention
-
Hilakivi-Clarke L. Nutritional modulation of terminal end buds: its relevance to breast cancer prevention. Curr Cancer Drug Targets 2007; 7: 465-74.
-
(2007)
Curr Cancer Drug Targets
, vol.7
, pp. 465-474
-
-
Hilakivi-Clarke, L.1
-
158
-
-
0036781142
-
Anti-oestrogenic prevention of breast cancer--the make or break point
-
Powles TJ. Anti-oestrogenic prevention of breast cancer--the make or break point. Nat Rev Cancer 2002; 2: 787-94.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 787-794
-
-
Powles, T.J.1
-
159
-
-
12144290788
-
Isoflavones stimulate estrogen receptor-mediated core histone acetylation
-
Hong T, Nakagawa T, Pan W, et al. Isoflavones stimulate estrogen receptor-mediated core histone acetylation. Biochem Biophys Res Commun 2004; 317: 259-64.
-
(2004)
Biochem Biophys Res Commun
, vol.317
, pp. 259-264
-
-
Hong, T.1
Nakagawa, T.2
Pan, W.3
-
160
-
-
42349103444
-
Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification
-
Majid S, Kikuno N, Nelles J, et al. Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification. Cancer Res 2008; 68: 2736-44.
-
(2008)
Cancer Res
, vol.68
, pp. 2736-2744
-
-
Majid, S.1
Kikuno, N.2
Nelles, J.3
-
161
-
-
46049103996
-
Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells
-
Kikuno N, Shiina H, Urakami S, et al. Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. Int J Cancer 2008; 123: 552-60.
-
(2008)
Int J Cancer
, vol.123
, pp. 552-560
-
-
Kikuno, N.1
Shiina, H.2
Urakami, S.3
-
162
-
-
55749097776
-
Genistein downregulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
-
Basak S, Pookot D, Noonan EJ, Dahiya R. Genistein downregulates androgen receptor by modulating HDAC6-Hsp90 chaperone function. Mol Cancer Ther 2008; 7: 3195-202.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3195-3202
-
-
Basak, S.1
Pookot, D.2
Noonan, E.J.3
Dahiya, R.4
-
163
-
-
26444451123
-
Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy
-
Fang MZ, Chen D, Sun Y, Jin Z, Christman JK, Yang CS. Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy. Clin Cancer Res 2005; 11: 7033-41.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7033-7041
-
-
Fang, M.Z.1
Chen, D.2
Sun, Y.3
Jin, Z.4
Christman, J.K.5
Yang, C.S.6
-
164
-
-
39749140314
-
Modulation of gene methylation by genistein or lycopene in breast cancer cells
-
King-Batoon A, Leszczynska JM, Klein CB. Modulation of gene methylation by genistein or lycopene in breast cancer cells. Environ Mol Mutagen 2008; 49: 36-45.
-
(2008)
Environ Mol Mutagen
, vol.49
, pp. 36-45
-
-
King-Batoon, A.1
Leszczynska, J.M.2
Klein, C.B.3
-
165
-
-
77955870856
-
Soy Phytoestrogens Modify DNA Methylation of GSTP1, RASSF1A, EPH2 and BRCA1 Promoter in Prostate Cancer Cells
-
Vardi A, Bosviel R, Rabiau N, et al. Soy Phytoestrogens Modify DNA Methylation of GSTP1, RASSF1A, EPH2 and BRCA1 Promoter in Prostate Cancer Cells. In vivo 2010; 24: 393-400.
-
(2010)
In Vivo
, vol.24
, pp. 393-400
-
-
Vardi, A.1
Bosviel, R.2
Rabiau, N.3
-
166
-
-
67449084948
-
Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms
-
Li Y, Liu L, Andrews LG, Tollefsbol TO. Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms. Int J Cancer 2009; 125: 286-96.
-
(2009)
Int J Cancer
, vol.125
, pp. 286-296
-
-
Li, Y.1
Liu, L.2
Andrews, L.G.3
Tollefsbol, T.O.4
-
167
-
-
64349112758
-
BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer
-
Majid S, Dar AA, Ahmad AE, et al. BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer. Carcinogenesis 2009; 30: 662-70.
-
(2009)
Carcinogenesis
, vol.30
, pp. 662-670
-
-
Majid, S.1
Dar, A.A.2
Ahmad, A.E.3
-
168
-
-
74549216395
-
Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-Cell translocation gene 3 in prostate cancer
-
Majid S, Dar AA, Shahryari V, et al. Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-Cell translocation gene 3 in prostate cancer. Cancer 2010; 116: 66-76.
-
(2010)
Cancer
, vol.116
, pp. 66-76
-
-
Majid, S.1
Dar, A.A.2
Shahryari, V.3
-
169
-
-
70949103350
-
Modulation of microRNA associated with ovarian cancer cells by genistein
-
Parker LP, Taylor DD, Kesterson J, Metzinger DS, Gercel-Taylor C. Modulation of microRNA associated with ovarian cancer cells by genistein. Eur J Gynaecol Oncol 2009; 30: 616-21.
-
(2009)
Eur J Gynaecol Oncol
, vol.30
, pp. 616-621
-
-
Parker, L.P.1
Taylor, D.D.2
Kesterson, J.3
Metzinger, D.S.4
Gercel-Taylor, C.5
-
170
-
-
69249096109
-
Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-tomesenchymal transition in gemcitabine-resistant pancreatic cancer cells
-
Li Y, VandenBoom TG, 2nd, Kong D, et al. Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-tomesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res 2009; 69: 6704-12.
-
(2009)
Cancer Res
, vol.69
, pp. 6704-6712
-
-
Li, Y.1
Vandenboom 2nd., T.G.2
Kong, D.3
-
171
-
-
77950822746
-
Regulation of minichromosome maintenance gene family by microRNA-1296 and genistein in prostate cancer
-
Majid S, Dar AA, Saini S, et al. Regulation of minichromosome maintenance gene family by microRNA-1296 and genistein in prostate cancer. Cancer Res 2010; 70: 2809-18.
-
(2010)
Cancer Res
, vol.70
, pp. 2809-2818
-
-
Majid, S.1
Dar, A.A.2
Saini, S.3
-
172
-
-
70349316774
-
Genistein inhibits growth of human uveal melanoma cells and affects microRNA-27a and target gene expression
-
Sun Q, Cong R, Yan H, et al. Genistein inhibits growth of human uveal melanoma cells and affects microRNA-27a and target gene expression. Oncol Rep 2009; 22: 563-7.
-
(2009)
Oncol Rep
, vol.22
, pp. 563-567
-
-
Sun, Q.1
Cong, R.2
Yan, H.3
-
173
-
-
3242721652
-
Genistein alters methylation patterns in mice
-
Day JK, Bauer AM, DesBordes C, et al. Genistein alters methylation patterns in mice. J Nutr 2002; 132: 2419S-23S.
-
(2002)
J Nutr
, vol.132
-
-
Day, J.K.1
Bauer, A.M.2
Desbordes, C.3
-
174
-
-
33645633542
-
Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome
-
Dolinoy DC, Weidman JR, Waterland RA, Jirtle RL. Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome. Environ Health Perspect 2006; 114: 567-72.
-
(2006)
Environ Health Perspect
, vol.114
, pp. 567-572
-
-
Dolinoy, D.C.1
Weidman, J.R.2
Waterland, R.A.3
Jirtle, R.L.4
-
175
-
-
52949108784
-
Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice
-
Guerrero-Bosagna CM, Sabat P, Valdovinos FS, Valladares LE, Clark SJ. Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice. BMC Physiol 2008; 8: 17.
-
(2008)
BMC Physiol
, vol.8
, pp. 17
-
-
Guerrero-Bosagna, C.M.1
Sabat, P.2
Valdovinos, F.S.3
Valladares, L.E.4
Clark, S.J.5
-
176
-
-
57349126317
-
Persistent hypomethylation in the promoter of nucleosomal binding protein 1 (Nsbp1) correlates with overexpression of Nsbp1 in mouse uteri neonatally exposed to diethylstilbestrol or genistein
-
Tang WY, Newbold R, Mardilovich K, et al. Persistent hypomethylation in the promoter of nucleosomal binding protein 1 (Nsbp1) correlates with overexpression of Nsbp1 in mouse uteri neonatally exposed to diethylstilbestrol or genistein. Endocrinology 2008; 149: 5922-31.
-
(2008)
Endocrinology
, vol.149
, pp. 5922-5931
-
-
Tang, W.Y.1
Newbold, R.2
Mardilovich, K.3
-
177
-
-
61649113446
-
Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women
-
Qin W, Zhu W, Shi H, et al. Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women. Nutr Cancer 2009; 61: 238-44.
-
(2009)
Nutr Cancer
, vol.61
, pp. 238-244
-
-
Qin, W.1
Zhu, W.2
Shi, H.3
-
178
-
-
65649091667
-
Modulation of DNA methylation by a sesquiterpene lactone parthenolide
-
Liu Z, Liu S, Xie Z, et al. Modulation of DNA methylation by a sesquiterpene lactone parthenolide. J Pharmacol Exp Ther 2009; 329: 505-14.
-
(2009)
J Pharmacol Exp Ther
, vol.329
, pp. 505-514
-
-
Liu, Z.1
Liu, S.2
Xie, Z.3
-
179
-
-
48449083208
-
Molecular basis of parthenolide-dependent proapoptotic activity in cancer cells
-
Pajak B, Gajkowska B, Orzechowski A. Molecular basis of parthenolide-dependent proapoptotic activity in cancer cells. Folia Histochem Cytobiol 2008; 46: 129-35.
-
(2008)
Folia Histochem Cytobiol
, vol.46
, pp. 129-135
-
-
Pajak, B.1
Gajkowska, B.2
Orzechowski, A.3
-
180
-
-
84934442428
-
Cancer chemopreventive effects of curcumin
-
Surh YJ, Chun KS. Cancer chemopreventive effects of curcumin. Adv Exp Med Biol 2007; 595: 149-72.
-
(2007)
Adv Exp Med Biol
, vol.595
, pp. 149-172
-
-
Surh, Y.J.1
Chun, K.S.2
-
181
-
-
51349137454
-
Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins
-
Kunnumakkara AB, Anand P, Aggarwal BB. Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins. Cancer Lett 2008; 269: 199-225.
-
(2008)
Cancer Lett
, vol.269
, pp. 199-225
-
-
Kunnumakkara, A.B.1
Anand, P.2
Aggarwal, B.B.3
-
182
-
-
73349094986
-
Curcumin and cancer cells: How many ways can curry kill tumor cells selectively?
-
Ravindran J, Prasad S, Aggarwal BB. Curcumin and cancer cells: how many ways can curry kill tumor cells selectively? AAPS J2009; 11: 495-510.
-
AAPS J2009
, vol.11
, pp. 495-510
-
-
Ravindran, J.1
Prasad, S.2
Aggarwal, B.B.3
-
183
-
-
77952528309
-
Synergistic role of curcumin with current therapeutics in colorectal cancer: Minireview
-
Patel BB, Majumdar AP. Synergistic role of curcumin with current therapeutics in colorectal cancer: minireview. Nutr Cancer 2009; 61: 842-6.
-
(2009)
Nutr Cancer
, vol.61
, pp. 842-846
-
-
Patel, B.B.1
Majumdar, A.P.2
-
184
-
-
10944243759
-
Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription
-
Balasubramanyam K, Varier RA, Altaf M, et al. Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. J Biol Chem 2004; 279: 51163-71.
-
(2004)
J Biol Chem
, vol.279
, pp. 51163-51171
-
-
Balasubramanyam, K.1
Varier, R.A.2
Altaf, M.3
-
185
-
-
15744370742
-
Curcumin-induced histone hypoacetylation: The role of reactive oxygen species
-
Kang J, Chen J, Shi Y, Jia J, Zhang Y. Curcumin-induced histone hypoacetylation: the role of reactive oxygen species. Biochem Pharmacol 2005; 69: 1205-13.
-
(2005)
Biochem Pharmacol
, vol.69
, pp. 1205-1213
-
-
Kang, J.1
Chen, J.2
Shi, Y.3
Jia, J.4
Zhang, Y.5
-
186
-
-
36248957463
-
Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells
-
Chen Y, Shu W, Chen W, Wu Q, Liu H, Cui G. Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells. Basic Clin Pharmacol Toxicol 2007; 101: 427-33.
-
(2007)
Basic Clin Pharmacol Toxicol
, vol.101
, pp. 427-433
-
-
Chen, Y.1
Shu, W.2
Chen, W.3
Wu, Q.4
Liu, H.5
Cui, G.6
-
187
-
-
0028867742
-
Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]
-
Singh S, Aggarwal BB. Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J Biol Chem 1995; 270: 24995-5000.
-
(1995)
J Biol Chem
, vol.270
, pp. 24995-5000
-
-
Singh, S.1
Aggarwal, B.B.2
-
188
-
-
58549094898
-
Curcumin is a potent DNA hypomethylation agent
-
Liu Z, Xie Z, Jones W, et al. Curcumin is a potent DNA hypomethylation agent. Bioorg Med Chem Lett 2009; 19: 706-9.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 706-709
-
-
Liu, Z.1
Xie, Z.2
Jones, W.3
-
189
-
-
41649090153
-
Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells
-
Sun M, Estrov Z, Ji Y, Coombes KR, Harris DH, Kurzrock R. Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells. Mol Cancer Therap 2008; 7: 464-73.
-
(2008)
Mol Cancer Therap
, vol.7
, pp. 464-473
-
-
Sun, M.1
Estrov, Z.2
Ji, Y.3
Coombes, K.R.4
Harris, D.H.5
Kurzrock, R.6
-
190
-
-
77951745289
-
Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF
-
Ali S, Ahmad A, Banerjee S, et al. Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF. Cancer Res 2010; 70: 3606-17.
-
(2010)
Cancer Res
, vol.70
, pp. 3606-3617
-
-
Ali, S.1
Ahmad, A.2
Banerjee, S.3
-
191
-
-
77955589719
-
Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway
-
Zhang J, Zhang T, Ti X, et al. Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway. Biochem Biophys Res Commun 2010; 399: 1-6.
-
(2010)
Biochem Biophys Res Commun
, vol.399
, pp. 1-6
-
-
Zhang, J.1
Zhang, T.2
Ti, X.3
-
192
-
-
0024520726
-
Ellagitannins as active constituents of medicinal plants
-
Okuda T, Yoshida T, Hatano T. Ellagitannins as active constituents of medicinal plants. Planta Med 1989; 55: 117-22.
-
(1989)
Planta Med
, vol.55
, pp. 117-122
-
-
Okuda, T.1
Yoshida, T.2
Hatano, T.3
-
193
-
-
67149144844
-
Ellagitannin (BJA3121), an antiproliferative natural polyphenol compound, can regulate the expression of MiRNAs in HepG2 cancer cells
-
Wen XY, Wu SY, Li ZQ, et al. Ellagitannin (BJA3121), an antiproliferative natural polyphenol compound, can regulate the expression of MiRNAs in HepG2 cancer cells. Phytother Res 2009; 23: 778-84.
-
(2009)
Phytother Res
, vol.23
, pp. 778-784
-
-
Wen, X.Y.1
Wu, S.Y.2
Li, Z.Q.3
-
194
-
-
67649238683
-
Glucosinolates in Brassica vegetables: The influence of the food supply chain on intake, bioavailability and human health
-
Verkerk R, Schreiner M, Krumbein A, et al. Glucosinolates in Brassica vegetables: the influence of the food supply chain on intake, bioavailability and human health. Mol Nutr Food Res 2009; 53 Suppl 2: S219.
-
Mol Nutr Food Res 2009; 53 Suppl
, vol.2
-
-
Verkerk, R.1
Schreiner, M.2
Krumbein, A.3
-
195
-
-
51549095960
-
Cancer chemotherapy with indole-3-carbinol, bis(3'-indolyl)methane and synthetic analogs
-
Safe S, Papineni S, Chintharlapalli S. Cancer chemotherapy with indole-3-carbinol, bis(3'-indolyl)methane and synthetic analogs. Cancer Lett 2008; 269: 326-38.
-
(2008)
Cancer Lett
, vol.269
, pp. 326-338
-
-
Safe, S.1
Papineni, S.2
Chintharlapalli, S.3
-
196
-
-
33745875948
-
Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from Brassicaceae
-
Pappa G, Lichtenberg M, Iori R, Barillari J, Bartsch H, Gerhauser C. Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from Brassicaceae. Mutat Res 2006; 599: 76-87.
-
(2006)
Mutat Res
, vol.599
, pp. 76-87
-
-
Pappa, G.1
Lichtenberg, M.2
Iori, R.3
Barillari, J.4
Bartsch, H.5
Gerhauser, C.6
-
197
-
-
76749152907
-
miR-146a suppresses invasion of pancreatic cancer cells
-
Li Y, Vandenboom TG, 2nd, Wang Z, et al. miR-146a suppresses invasion of pancreatic cancer cells. Cancer Res 2010; 70: 1486-95.
-
(2010)
Cancer Res
, vol.70
, pp. 1486-1495
-
-
Li, Y.1
Vandenboom 2nd., T.G.2
Wang, Z.3
-
198
-
-
61449208911
-
Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke
-
Izzotti A, Calin GA, Arrigo P, Steele VE, Croce CM, De Flora S. Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke. FASEB J 2009; 23: 806-12.
-
(2009)
FASEB J
, vol.23
, pp. 806-812
-
-
Izzotti, A.1
Calin, G.A.2
Arrigo, P.3
Steele, V.E.4
Croce, C.M.5
de Flora, S.6
-
199
-
-
70450224878
-
Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways
-
Bhattacharya K, Samanta SK, Tripathi R, et al. Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways. Biochem Pharmacol 2010; 79: 361-72.
-
(2010)
Biochem Pharmacol
, vol.79
, pp. 361-372
-
-
Bhattacharya, K.1
Samanta, S.K.2
Tripathi, R.3
-
200
-
-
77949865239
-
Fluorescent epigenetic small molecule induces expression of the tumor suppressor rasassociation domain family 1A and inhibits human prostate xenograft
-
Sheikh KD, Banerjee PP, Jagadeesh S, et al. Fluorescent epigenetic small molecule induces expression of the tumor suppressor rasassociation domain family 1A and inhibits human prostate xenograft. J Med Chem 2010; 53: 2376-82.
-
(2010)
J Med Chem
, vol.53
, pp. 2376-2382
-
-
Sheikh, K.D.1
Banerjee, P.P.2
Jagadeesh, S.3
-
201
-
-
0037008775
-
An essential role for DNA methyltransferase DNMT3B in cancer cell survival
-
Beaulieu N, Morin S, Chute IC, Robert MF, Nguyen H, MacLeod AR. An essential role for DNA methyltransferase DNMT3B in cancer cell survival. J Biol Chem 2002; 277: 28176-81.
-
(2002)
J Biol Chem
, vol.277
, pp. 28176-28181
-
-
Beaulieu, N.1
Morin, S.2
Chute, I.C.3
Robert, M.F.4
Nguyen, H.5
Macleod, A.R.6
-
202
-
-
34250377801
-
Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs
-
Blecha JE, Anderson MO, Chow JM, et al. Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs. Bioorg Med Chem Lett 2007; 17: 4026-9.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 4026-4029
-
-
Blecha, J.E.1
Anderson, M.O.2
Chow, J.M.3
-
203
-
-
77954288819
-
Molecular mechanisms and clinical applications of nordihydroguaiaretic acid (NDGA) and its derivatives: An update
-
[Lu JM, Nurko J, Weakley SM, et al. Molecular mechanisms and clinical applications of nordihydroguaiaretic acid (NDGA) and its derivatives: an update. Med Sci Monit 2010; 16: RA93-100.
-
(2010)
Med Sci Monit
, vol.16
-
-
Lu, J.M.1
Nurko, J.2
Weakley, S.M.3
-
204
-
-
38549094538
-
A pilot dose-escalation study of the effects of nordihydroguareacetic acid on hormone and prostate specific antigen levels in patients with relapsed prostate cancer
-
Ryan CJ, Harzstark AH, Rosenberg J, et al. A pilot dose-escalation study of the effects of nordihydroguareacetic acid on hormone and prostate specific antigen levels in patients with relapsed prostate cancer. BJU Int 2008; 101: 436-9.
-
(2008)
BJU Int
, vol.101
, pp. 436-439
-
-
Ryan, C.J.1
Harzstark, A.H.2
Rosenberg, J.3
-
205
-
-
38349052930
-
Reactivation of methylation-silenced tumor suppressor gene p16INK4a by nordihydroguaiaretic acid and its implication in G1 cell cycle arrest
-
Cui Y, Lu C, Liu L, et al. Reactivation of methylation-silenced tumor suppressor gene p16INK4a by nordihydroguaiaretic acid and its implication in G1 cell cycle arrest. Life Sci 2008; 82: 247-55.
-
(2008)
Life Sci
, vol.82
, pp. 247-255
-
-
Cui, Y.1
Lu, C.2
Liu, L.3
-
206
-
-
42349113438
-
Nordihydroguaiaretic acid restores expression of silenced E-cadherin gene in human breast cancer cell lines and xenografts
-
Cui Y, Lu C, Kang A, et al. Nordihydroguaiaretic acid restores expression of silenced E-cadherin gene in human breast cancer cell lines and xenografts. Anticancer Drugs 2008; 19: 487-94.
-
(2008)
Anticancer Drugs
, vol.19
, pp. 487-494
-
-
Cui, Y.1
Lu, C.2
Kang, A.3
-
207
-
-
45049086493
-
2'-Deoxy-N4-[2-(4- nitrophenyl)ethoxycarbonyl]-5-azacytidine: A novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1
-
Byun HM, Choi SH, Laird PW, et al. 2'-Deoxy-N4-[2-(4- nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1. Cancer Lett 2008; 266: 238-48.
-
(2008)
Cancer Lett
, vol.266
, pp. 238-248
-
-
Byun, H.M.1
Choi, S.H.2
Laird, P.W.3
-
208
-
-
51349149762
-
Multitargeted therapy of cancer by lycopene
-
van Breemen RB, Pajkovic N. Multitargeted therapy of cancer by lycopene. Cancer Lett 2008; 269: 339-51.
-
(2008)
Cancer Lett
, vol.269
, pp. 339-351
-
-
van Breemen, R.B.1
Pajkovic, N.2
-
209
-
-
34247606510
-
Molecular basis for chemoprevention by sulforaphane: A comprehensive review
-
Juge N, Mithen RF, Traka M. Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell Mol Life Sci 2007; 64: 1105-27.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 1105-1127
-
-
Juge, N.1
Mithen, R.F.2
Traka, M.3
-
210
-
-
34548445866
-
Discovery and development of sulforaphane as a cancer chemopreventive phytochemical
-
Zhang Y, Tang L. Discovery and development of sulforaphane as a cancer chemopreventive phytochemical. Acta Pharmacol Sin 2007; 28: 1343-54.
-
(2007)
Acta Pharmacol Sin
, vol.28
, pp. 1343-1354
-
-
Zhang, Y.1
Tang, L.2
-
211
-
-
51349088974
-
Multi-targeted prevention of cancer by sulforaphane
-
Clarke JD, Dashwood RH, Ho E. Multi-targeted prevention of cancer by sulforaphane. Cancer Lett 2008; 269: 291-304.
-
(2008)
Cancer Lett
, vol.269
, pp. 291-304
-
-
Clarke, J.D.1
Dashwood, R.H.2
Ho, E.3
-
212
-
-
0034538640
-
Inhibition of carcinogenesis by isothiocyanates
-
Hecht SS. Inhibition of carcinogenesis by isothiocyanates. Drug Metab Rev 2000; 32: 395-411.
-
(2000)
Drug Metab Rev
, vol.32
, pp. 395-411
-
-
Hecht, S.S.1
-
213
-
-
77449106593
-
Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention
-
Cheung KL, Kong AN. Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention. AAPS J 2010; 12: 87-97.
-
(2010)
AAPS J
, vol.12
, pp. 87-97
-
-
Cheung, K.L.1
Kong, A.N.2
-
214
-
-
77149128638
-
Inhibition of autophagy potentiates sulforaphane-induced apoptosis in human colon cancer cells
-
Nishikawa T, Tsuno NH, Okaji Y, et al. Inhibition of autophagy potentiates sulforaphane-induced apoptosis in human colon cancer cells. Ann Surg Oncol 2010; 17: 592-602.
-
(2010)
Ann Surg Oncol
, vol.17
, pp. 592-602
-
-
Nishikawa, T.1
Tsuno, N.H.2
Okaji, Y.3
-
215
-
-
33745282435
-
Sulforaphane causes autophagy to inhibit release of cytochrome C and apoptosis in human prostate cancer cells
-
Herman-Antosiewicz A, Johnson DE, Singh SV. Sulforaphane causes autophagy to inhibit release of cytochrome C and apoptosis in human prostate cancer cells. Cancer Res 2006; 66: 5828-35.
-
(2006)
Cancer Res
, vol.66
, pp. 5828-5835
-
-
Herman-Antosiewicz, A.1
Johnson, D.E.2
Singh, S.V.3
-
216
-
-
33947244444
-
Phenethyl isothiocyanate inhibits angiogenesis in vitro and ex vivo
-
Xiao D, Singh SV. Phenethyl isothiocyanate inhibits angiogenesis in vitro and ex vivo. Cancer Res 2007; 67: 2239-46.
-
(2007)
Cancer Res
, vol.67
, pp. 2239-2246
-
-
Xiao, D.1
Singh, S.V.2
-
217
-
-
65949086045
-
Atg5 regulates phenethyl isothiocyanate-induced autophagic and apoptotic cell death in human prostate cancer cells
-
Bommareddy A, Hahm ER, Xiao D, et al. Atg5 regulates phenethyl isothiocyanate-induced autophagic and apoptotic cell death in human prostate cancer cells. Cancer Res 2009; 69: 3704-12.
-
(2009)
Cancer Res
, vol.69
, pp. 3704-3712
-
-
Bommareddy, A.1
Hahm, E.R.2
Xiao, D.3
-
218
-
-
33748146888
-
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate
-
Trachootham D, Zhou Y, Zhang H, et al. Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate. Cancer Cell 2006; 10: 241-52.
-
(2006)
Cancer Cell
, vol.10
, pp. 241-252
-
-
Trachootham, D.1
Zhou, Y.2
Zhang, H.3
-
219
-
-
84859450158
-
-
[http://www.cancer.gov/clinicaltrials.
-
-
-
-
220
-
-
63049105405
-
Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: Studies with sulforaphane and garlic organosulfur compounds
-
Nian H, Delage B, Ho E, Dashwood RH. Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds. Environ Mol Mutagen 2009; 50: 213-21.
-
(2009)
Environ Mol Mutagen
, vol.50
, pp. 213-221
-
-
Nian, H.1
Delage, B.2
Ho, E.3
Dashwood, R.H.4
-
221
-
-
4143130097
-
A novel mechanism of chemoprotection by sulforaphane: Inhibition of histone deacetylase
-
Myzak MC, Karplus PA, Chung FL, Dashwood RH. A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase. Cancer Res 2004; 64: 5767-74.
-
(2004)
Cancer Res
, vol.64
, pp. 5767-5774
-
-
Myzak, M.C.1
Karplus, P.A.2
Chung, F.L.3
Dashwood, R.H.4
-
222
-
-
33645324413
-
Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells
-
Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E. Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells. Carcinogenesis 2006; 27: 811-9.
-
(2006)
Carcinogenesis
, vol.27
, pp. 811-819
-
-
Myzak, M.C.1
Hardin, K.2
Wang, R.3
Dashwood, R.H.4
Ho, E.5
-
223
-
-
34147135143
-
Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines
-
Pledgie-Tracy A, Sobolewski MD, Davidson NE. Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines. Mol Cancer Ther 2007; 6: 1013-21.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1013-1021
-
-
Pledgie-Tracy, A.1
Sobolewski, M.D.2
Davidson, N.E.3
-
224
-
-
70349741087
-
Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6
-
Gibbs A, Schwartzman J, Deng V, Alumkal J. Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6. Proc Natl Acad Sci U S A 2009; 106: 16663-8.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 16663-16668
-
-
Gibbs, A.1
Schwartzman, J.2
Deng, V.3
Alumkal, J.4
-
225
-
-
77955352742
-
Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines
-
Meeran SM, Patel SN, Tollefsbol TO. Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines. PLoS One 2010; 5: e11457.
-
(2010)
PLoS One
, vol.e11457
, pp. 5
-
-
Meeran, S.M.1
Patel, S.N.2
Tollefsbol, T.O.3
-
226
-
-
34548456881
-
Dietary histone deacetylase inhibitors: From cells to mice to man
-
Dashwood RH, Ho E. Dietary histone deacetylase inhibitors: from cells to mice to man. Semin Cancer Biol 2007; 17: 363-9.
-
(2007)
Semin Cancer Biol
, vol.17
, pp. 363-369
-
-
Dashwood, R.H.1
Ho, E.2
-
227
-
-
33645825587
-
Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice
-
Myzak MC, Dashwood WM, Orner GA, Ho E, Dashwood RH. Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice. FASEB J 2006; 20: 506-8.
-
(2006)
FASEB J
, vol.20
, pp. 506-508
-
-
Myzak, M.C.1
Dashwood, W.M.2
Orner, G.A.3
Ho, E.4
Dashwood, R.H.5
-
228
-
-
33846838750
-
Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects
-
Myzak MC, Tong P, Dashwood WM, Dashwood RH, Ho E. Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects. Exp Biol Med (Maywood) 2007; 232: 227-34.
-
(2007)
Exp Biol Med (Maywood)
, vol.232
, pp. 227-234
-
-
Myzak, M.C.1
Tong, P.2
Dashwood, W.M.3
Dashwood, R.H.4
Ho, E.5
-
229
-
-
33846217828
-
Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer
-
Wang LG, Beklemisheva A, Liu XM, Ferrari AC, Feng J, Chiao JW. Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer. Mol Carcinog 2007; 46: 24-31.
-
(2007)
Mol Carcinog
, vol.46
, pp. 24-31
-
-
Wang, L.G.1
Beklemisheva, A.2
Liu, X.M.3
Ferrari, A.C.4
Feng, J.5
Chiao, J.W.6
-
230
-
-
48749118821
-
De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc
-
Wang LG, Liu XM, Fang Y, et al. De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc. Int J Oncol 2008; 33: 375-80.
-
(2008)
Int J Oncol
, vol.33
, pp. 375-380
-
-
Wang, L.G.1
Liu, X.M.2
Fang, Y.3
-
231
-
-
77956544792
-
Prostate cancer chemopreventive activity of phenethyl isothiocyanate through epigenetic regulation (Review)
-
Wang LG, Chiao JW. Prostate cancer chemopreventive activity of phenethyl isothiocyanate through epigenetic regulation (Review). Int J Oncol 2010; 37: 533-9.
-
(2010)
Int J Oncol
, vol.37
, pp. 533-539
-
-
Wang, L.G.1
Chiao, J.W.2
-
232
-
-
77649196362
-
Chemoprevention of cigarette smoke-induced alterations of MicroRNA expression in rat lungs
-
Izzotti A, Calin GA, Steele VE, et al. Chemoprevention of cigarette smoke-induced alterations of MicroRNA expression in rat lungs. Cancer Prev Res (Phila Pa) 2010; 3: 62-72.
-
(2010)
Cancer Prev Res (Phila Pa)
, vol.3
, pp. 62-72
-
-
Izzotti, A.1
Calin, G.A.2
Steele, V.E.3
-
233
-
-
77952304948
-
Modulation of microRNA expression by budesonide, phenethyl isothiocyanate, and cigarette smoke in mouse liver and lung
-
Izzotti A, Larghero P, Cartiglia C, et al. Modulation of microRNA expression by budesonide, phenethyl isothiocyanate, and cigarette smoke in mouse liver and lung. Carcinogenesis 2010; 31: 894-901.
-
(2010)
Carcinogenesis
, vol.31
, pp. 894-901
-
-
Izzotti, A.1
Larghero, P.2
Cartiglia, C.3
-
234
-
-
65349138314
-
Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways
-
Lu Q, Lin X, Feng J, et al. Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways. J Hematol Oncol 2008; 1: 6.
-
(2008)
J Hematol Oncol
, vol.1
, pp. 6
-
-
Lu, Q.1
Lin, X.2
Feng, J.3
-
235
-
-
33645822781
-
Epigenetic mechanism of growth inhibition induced by phenylhexyl isothiocyanate in prostate cancer cells
-
Beklemisheva AA, Fang Y, Feng J, Ma X, Dai W, Chiao JW. Epigenetic mechanism of growth inhibition induced by phenylhexyl isothiocyanate in prostate cancer cells. Anticancer Res 2006; 26: 1225-30.
-
(2006)
Anticancer Res
, vol.26
, pp. 1225-1230
-
-
Beklemisheva, A.A.1
Fang, Y.2
Feng, J.3
Ma, X.4
Dai, W.5
Chiao, J.W.6
-
236
-
-
33646823481
-
Phenylhexyl isothiocyanate inhibits histone deacetylases and remodels chromatins to induce growth arrest in human leukemia cells
-
Ma X, Fang Y, Beklemisheva A, et al. Phenylhexyl isothiocyanate inhibits histone deacetylases and remodels chromatins to induce growth arrest in human leukemia cells. Int J Oncol 2006; 28: 1287-93.
-
(2006)
Int J Oncol
, vol.28
, pp. 1287-1293
-
-
Ma, X.1
Fang, Y.2
Beklemisheva, A.3
-
237
-
-
70449792133
-
Experiment study of PHI on histone methylation and acetylation in Molt-4 cells
-
Huang YQ, Ma XD, Zhen RJ, Chiao JW, Liu DL. [Experiment study of PHI on histone methylation and acetylation in Molt-4 cells]. Zhonghua Xue Ye Xue Za Zhi 2007; 28: 612-5.
-
(2007)
Zhonghua Xue Ye Xue Za Zhi
, vol.28
, pp. 612-615
-
-
Huang, Y.Q.1
Ma, X.D.2
Zhen, R.J.3
Chiao, J.W.4
Liu, D.L.5
-
238
-
-
73249153643
-
Deficient histone acetylation in acute leukemia and the correction by an isothiocyanate
-
Xiao L, Huang Y, Zhen R, Chiao JW, Liu D, Ma X. Deficient histone acetylation in acute leukemia and the correction by an isothiocyanate. Acta Haematol 2010; 123: 71-6.
-
(2010)
Acta Haematol
, vol.123
, pp. 71-76
-
-
Xiao, L.1
Huang, Y.2
Zhen, R.3
Chiao, J.W.4
Liu, D.5
Ma, X.6
-
239
-
-
77955492958
-
Phenylhexyl isothiocyanate(PHI) regulates histone methylation and acetylation and induces apoptosis in SMMC-7721 cells
-
Huang YQ, Ma XD, Lai YD, Wang XZ, Chiao JW, Liu DL. [Phenylhexyl isothiocyanate(PHI) regulates histone methylation and acetylation and induces apoptosis in SMMC-7721 cells]. Zhonghua Gan Zang Bing Za Zhi 2010; 18: 209-12.
-
(2010)
Zhonghua Gan Zang Bing Za Zhi
, vol.18
, pp. 209-212
-
-
Huang, Y.Q.1
Ma, X.D.2
Lai, Y.D.3
Wang, X.Z.4
Chiao, J.W.5
Liu, D.L.6
-
240
-
-
0034774806
-
Allium vegetables and organosulfur compounds: Do they help prevent cancer?
-
Bianchini F, Vainio H. Allium vegetables and organosulfur compounds: do they help prevent cancer? Environ Health Perspect 2001; 109: 893-902.
-
(2001)
Environ Health Perspect
, vol.109
, pp. 893-902
-
-
Bianchini, F.1
Vainio, H.2
-
241
-
-
51349109112
-
Multitargeted prevention and therapy of cancer by diallyl trisulfide and related Allium vegetable-derived organosulfur compounds
-
Powolny AA, Singh SV. Multitargeted prevention and therapy of cancer by diallyl trisulfide and related Allium vegetable-derived organosulfur compounds. Cancer Lett 2008; 269: 305-14.
-
(2008)
Cancer Lett
, vol.269
, pp. 305-314
-
-
Powolny, A.A.1
Singh, S.V.2
-
242
-
-
0036437194
-
Induction of histone acetylation and inhibition of growth of mouse erythroleukemia cells by S-allylmercaptocysteine
-
Lea MA, Rasheed M, Randolph VM, Khan F, Shareef A, desBordes C. Induction of histone acetylation and inhibition of growth of mouse erythroleukemia cells by S-allylmercaptocysteine. Nutr Cancer 2002; 43: 90-102.
-
(2002)
Nutr Cancer
, vol.43
, pp. 90-102
-
-
Lea, M.A.1
Rasheed, M.2
Randolph, V.M.3
Khan, F.4
Shareef, A.5
Desbordes, C.6
-
243
-
-
51849103354
-
Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter
-
Nian H, Delage B, Pinto JT, Dashwood RH. Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter. Carcinogenesis 2008; 29: 1816-24.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1816-1824
-
-
Nian, H.1
Delage, B.2
Pinto, J.T.3
Dashwood, R.H.4
-
244
-
-
48349139851
-
Diallyl disulfide increases histone acetylation in colon cells in vitro and in vivo
-
Druesne-Pecollo N, Chaumontet C, Latino-Martel P. Diallyl disulfide increases histone acetylation in colon cells in vitro and in vivo. Nutr Rev 2008; 66 Suppl 1: S39-41.
-
(2008)
Nutr Rev
, vol.66
, Issue.SUPPL. 1
-
-
Druesne-Pecollo, N.1
Chaumontet, C.2
Latino-Martel, P.3
-
245
-
-
33846452520
-
In vivo treatment by diallyl disulfide increases histone acetylation in rat colonocytes
-
Druesne-Pecollo N, Chaumontet C, Pagniez A, et al. In vivo treatment by diallyl disulfide increases histone acetylation in rat colonocytes. Biochem Biophys Res Commun 2007; 354: 140-7.
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 140-147
-
-
Druesne-Pecollo, N.1
Chaumontet, C.2
Pagniez, A.3
-
246
-
-
33750291392
-
The aureolic acid family of antitumor compounds: Structure, mode of action, biosynthesis, and novel derivatives
-
Lombo F, Menendez N, Salas JA, Mendez C. The aureolic acid family of antitumor compounds: structure, mode of action, biosynthesis, and novel derivatives. Appl Microbiol Biotechnol 2006; 73: 1-14.
-
(2006)
Appl Microbiol Biotechnol
, vol.73
, pp. 1-14
-
-
Lombo, F.1
Menendez, N.2
Salas, J.A.3
Mendez, C.4
-
247
-
-
34748837820
-
Mithramycin A inhibits DNA methyltransferase and metastasis potential of lung cancer cells
-
Lin RK, Hsu CH, Wang YC. Mithramycin A inhibits DNA methyltransferase and metastasis potential of lung cancer cells. Anticancer Drugs 2007; 18: 1157-64.
-
(2007)
Anticancer Drugs
, vol.18
, pp. 1157-1164
-
-
Lin, R.K.1
Hsu, C.H.2
Wang, Y.C.3
-
248
-
-
70349578960
-
Expression of miR-210 during erythroid differentiation and induction of gamma-globin gene expression
-
Bianchi N, Zuccato C, Lampronti I, Borgatti M, Gambari R. Expression of miR-210 during erythroid differentiation and induction of gamma-globin gene expression. BMB Rep 2009; 42: 493-9.
-
(2009)
BMB Rep
, vol.42
, pp. 493-499
-
-
Bianchi, N.1
Zuccato, C.2
Lampronti, I.3
Borgatti, M.4
Gambari, R.5
-
249
-
-
0034326799
-
Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin
-
Han JW, Ahn SH, Park SH, et al. Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin. Cancer Res 2000; 60: 6068-74.
-
(2000)
Cancer Res
, vol.60
, pp. 6068-6074
-
-
Han, J.W.1
Ahn, S.H.2
Park, S.H.3
-
250
-
-
39849091786
-
Histone deacetylase inhibitor apicidin downregulates DNA methyltransferase 1 expression and induces repressive histone modifications via recruitment of corepressor complex to promoter region in human cervix cancer cells
-
You JS, Kang JK, Lee EK, et al. Histone deacetylase inhibitor apicidin downregulates DNA methyltransferase 1 expression and induces repressive histone modifications via recruitment of corepressor complex to promoter region in human cervix cancer cells. Oncogene 2008; 27: 1376-86.
-
(2008)
Oncogene
, vol.27
, pp. 1376-1386
-
-
You, J.S.1
Kang, J.K.2
Lee, E.K.3
-
251
-
-
33644837942
-
Non-steroidal anti-inflammatory drugs for cancer prevention: Promise, perils and pharmacogenetics
-
Ulrich CM, Bigler J, Potter JD. Non-steroidal anti-inflammatory drugs for cancer prevention: promise, perils and pharmacogenetics. Nat Rev Cancer 2006; 6: 130-40.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 130-140
-
-
Ulrich, C.M.1
Bigler, J.2
Potter, J.D.3
-
252
-
-
0035496616
-
Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2
-
Gupta RA, Dubois RN. Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2. Nat Rev Cancer 2001; 1: 11-21.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 11-21
-
-
Gupta, R.A.1
Dubois, R.N.2
-
253
-
-
64049109107
-
Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung
-
Harris RE. Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung. Inflammopharmacology 2009; 17: 55-67.
-
(2009)
Inflammopharmacology
, vol.17
, pp. 55-67
-
-
Harris, R.E.1
-
254
-
-
4944242891
-
Polyamines and cancer: Old molecules, new understanding
-
Gerner EW, Meyskens FL, Jr. Polyamines and cancer: old molecules, new understanding. Nat Rev Cancer 2004; 4: 781-92.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 781-792
-
-
Gerner, E.W.1
Meyskens Jr., F.L.2
-
255
-
-
0345535621
-
Development of difluoromethylornithine (DFMO) as a chemoprevention agent
-
Meyskens FL, Jr., Gerner EW. Development of difluoromethylornithine (DFMO) as a chemoprevention agent. Clin Cancer Res 1999; 5: 945-51.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 945-951
-
-
Meyskens Jr., F.L.1
Gerner, E.W.2
-
256
-
-
55549132996
-
Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: A randomized placebo-controlled, double-blind trial
-
Meyskens FL, Jr., McLaren CE, Pelot D, et al. Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial. Cancer Prev Res (Phila Pa) 2008; 1: 32-8.
-
(2008)
Cancer Prev Res (Phila Pa)
, vol.1
, pp. 32-38
-
-
Meyskens Jr., F.L.1
McLaren, C.E.2
Pelot, D.3
-
257
-
-
6444226573
-
Modulation by celecoxib and difluoromethylornithine of the methylation of DNA and the estrogen receptor-alpha gene in rat colon tumors
-
Pereira MA, Tao L, Wang W, et al. Modulation by celecoxib and difluoromethylornithine of the methylation of DNA and the estrogen receptor-alpha gene in rat colon tumors. Carcinogenesis 2004; 25: 1917-23.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1917-1923
-
-
Pereira, M.A.1
Tao, L.2
Wang, W.3
-
258
-
-
0842325660
-
Modulation of DNA hypomethylation as a surrogate endpoint biomarker for chemoprevention of colon cancer
-
Tao L, Wang W, Kramer PM, Lubet RA, Steele VE, Pereira MA. Modulation of DNA hypomethylation as a surrogate endpoint biomarker for chemoprevention of colon cancer. Mol Carcinog 2004; 39: 79-84.
-
(2004)
Mol Carcinog
, vol.39
, pp. 79-84
-
-
Tao, L.1
Wang, W.2
Kramer, P.M.3
Lubet, R.A.4
Steele, V.E.5
Pereira, M.A.6
-
260
-
-
27144509196
-
DNA methyltransferase inhibitors and the development of epigenetic cancer therapies
-
Lyko F, Brown R. DNA methyltransferase inhibitors and the development of epigenetic cancer therapies. J Natl Cancer Inst 2005; 97: 1498-506.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1498-1506
-
-
Lyko, F.1
Brown, R.2
-
261
-
-
53249121556
-
Sirtuins--novel therapeutic targets to treat age-associated diseases
-
Lavu S, Boss O, Elliott PJ, Lambert PD. Sirtuins--novel therapeutic targets to treat age-associated diseases. Nat Rev Drug Discov 2008; 7: 841-53.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 841-853
-
-
Lavu, S.1
Boss, O.2
Elliott, P.J.3
Lambert, P.D.4
-
262
-
-
58849158388
-
How does SIRT1 affect metabolism, senescence and cancer?
-
Brooks CL, Gu W. How does SIRT1 affect metabolism, senescence and cancer? Nat Rev Cancer 2009; 9: 123-8.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 123-128
-
-
Brooks, C.L.1
Gu, W.2
-
263
-
-
77952714326
-
SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling
-
Holloway KR, Calhoun TN, Saxena M, et al. SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling. Proc Natl Acad Sci U S A 2010; 107: 9216-21.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 9216-9221
-
-
Holloway, K.R.1
Calhoun, T.N.2
Saxena, M.3
-
264
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
Howitz KT, Bitterman KJ, Cohen HY, et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 2003; 425: 191-6.
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
-
265
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen HY, Miller C, Bitterman KJ, et al. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 2004; 305: 390-2.
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
-
266
-
-
0031561513
-
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
-
Jang M, Cai L, Udeani GO, et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 1997; 275: 218-20.
-
(1997)
Science
, vol.275
, pp. 218-220
-
-
Jang, M.1
Cai, L.2
Udeani, G.O.3
-
267
-
-
45849124668
-
Resveratrol as an inhibitor of carcinogenensis
-
Pezzuto JM. Resveratrol as an inhibitor of carcinogenensis. Pharm Biol 2008; 46: 443-573.
-
(2008)
Pharm Biol
, vol.46
, pp. 443-573
-
-
Pezzuto, J.M.1
-
268
-
-
51349132313
-
Cancer chemopreventive and therapeutic potential of resveratrol: Mechanistic perspectives
-
Kundu JK, Surh YJ. Cancer chemopreventive and therapeutic potential of resveratrol: mechanistic perspectives. Cancer Lett 2008; 269: 243-61.
-
(2008)
Cancer Lett
, vol.269
, pp. 243-261
-
-
Kundu, J.K.1
Surh, Y.J.2
-
269
-
-
33745962138
-
Therapeutic potential of resveratrol: The in vivo evidence
-
Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 2006; 5: 493-506.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 493-506
-
-
Baur, J.A.1
Sinclair, D.A.2
-
270
-
-
77957721534
-
Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFbeta signaling pathway in SW480 cells
-
Tili E, Michaille JJ, Alder H, et al. Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFbeta signaling pathway in SW480 cells. Biochem Pharmacol 2010; 80: 2057-65.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 2057-2065
-
-
Tili, E.1
Michaille, J.J.2
Alder, H.3
-
271
-
-
77956290858
-
Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD
-
Tili E, Michaille JJ, Adair B, et al. Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD. Carcinogenesis 2010; 31: 1561-66.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1561-1566
-
-
Tili, E.1
Michaille, J.J.2
Adair, B.3
-
272
-
-
55449104382
-
The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases
-
Olaharski AJ, Rine J, Marshall BL, et al. The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases. PLoS Genet 2005; 1: e77.
-
(2005)
PLoS Genet
, vol.e77
, pp. 1
-
-
Olaharski, A.J.1
Rine, J.2
Marshall, B.L.3
-
273
-
-
33646254136
-
Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes
-
Heltweg B, Gatbonton T, Schuler AD, et al. Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes. Cancer Res 2006; 66: 4368-77.
-
(2006)
Cancer Res
, vol.66
, pp. 4368-4377
-
-
Heltweg, B.1
Gatbonton, T.2
Schuler, A.D.3
-
274
-
-
4143089466
-
Implications of small molecule activators and inhibitors of histone acetyltransferases in chromatin therapy
-
Varier RA, Swaminathan V, Balasubramanyam K, Kundu TK. Implications of small molecule activators and inhibitors of histone acetyltransferases in chromatin therapy. Biochem Pharmacol 2004; 68: 1215-20.
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 1215-1220
-
-
Varier, R.A.1
Swaminathan, V.2
Balasubramanyam, K.3
Kundu, T.K.4
-
276
-
-
33746581782
-
Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation
-
Sun Y, Jiang X, Chen S, Price BD. Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation. FEBS Lett 2006; 580: 4353-6.
-
(2006)
FEBS Lett
, vol.580
, pp. 4353-4356
-
-
Sun, Y.1
Jiang, X.2
Chen, S.3
Price, B.D.4
-
277
-
-
46749127067
-
Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factorkappaBalpha kinase, leading to potentiation of apoptosis
-
Sung B, Pandey MK, Ahn KS, et al. Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factorkappaBalpha kinase, leading to potentiation of apoptosis. Blood 2008; 111: 4880-91.
-
(2008)
Blood
, vol.111
, pp. 4880-4891
-
-
Sung, B.1
Pandey, M.K.2
Ahn, K.S.3
-
278
-
-
70349237039
-
Emerging role of Garcinol, the antioxidant chalcone from Garcinia indica Choisy and its synthetic analogs
-
Padhye S, Ahmad A, Oswal N, Sarkar FH. Emerging role of Garcinol, the antioxidant chalcone from Garcinia indica Choisy and its synthetic analogs. J Hematol Oncol 2009; 2: 38.
-
(2009)
J Hematol Oncol
, vol.2
, pp. 38
-
-
Padhye, S.1
Ahmad, A.2
Oswal, N.3
Sarkar, F.H.4
-
279
-
-
4043146501
-
Polyisoprenylated benzophenone, garcinol, a natural histone acetyltransferase inhibitor, represses chromatin transcription and alters global gene expression
-
Balasubramanyam K, Altaf M, Varier RA, et al. Polyisoprenylated benzophenone, garcinol, a natural histone acetyltransferase inhibitor, represses chromatin transcription and alters global gene expression. J Biol Chem 2004; 279: 33716-26.
-
(2004)
J Biol Chem
, vol.279
, pp. 33716-33726
-
-
Balasubramanyam, K.1
Altaf, M.2
Varier, R.A.3
-
280
-
-
77950796660
-
Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins
-
Prasad S, Ravindran J, Sung B, Pandey MK, Aggarwal BB. Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins. Mol Cancer Ther 2010; 9: 856-68.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 856-868
-
-
Prasad, S.1
Ravindran, J.2
Sung, B.3
Pandey, M.K.4
Aggarwal, B.B.5
-
282
-
-
70350417325
-
Bile acids: Regulation of apoptosis by ursodeoxycholic acid
-
Amaral JD, Viana RJ, Ramalho RM, Steer CJ, Rodrigues CM. Bile acids: regulation of apoptosis by ursodeoxycholic acid. J Lipid Res 2009; 50: 1721-34.
-
(2009)
J Lipid Res
, vol.50
, pp. 1721-1734
-
-
Amaral, J.D.1
Viana, R.J.2
Ramalho, R.M.3
Steer, C.J.4
Rodrigues, C.M.5
-
283
-
-
33751566970
-
Ursodeoxycholic acid modulates histone acetylation and induces differentiation and senescence
-
Akare S, Jean-Louis S, Chen W, Wood DJ, Powell AA, Martinez JD. Ursodeoxycholic acid modulates histone acetylation and induces differentiation and senescence. Int J Cancer 2006; 119: 2958-69.
-
(2006)
Int J Cancer
, vol.119
, pp. 2958-2969
-
-
Akare, S.1
Jean-Louis, S.2
Chen, W.3
Wood, D.J.4
Powell, A.A.5
Martinez, J.D.6
-
284
-
-
67649305191
-
Epigenetics in cancer: Targeting chromatin modifications
-
Ellis L, Atadja PW, Johnstone RW. Epigenetics in cancer: targeting chromatin modifications. Mol Cancer Ther 2009; 8: 1409-20.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1409-1420
-
-
Ellis, L.1
Atadja, P.W.2
Johnstone, R.W.3
-
285
-
-
33947214077
-
Chaetocin: A promising new antimyeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress
-
Isham CR, Tibodeau JD, Jin W, Xu R, Timm MM, Bible KC. Chaetocin: a promising new antimyeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress. Blood 2007; 109: 2579-88.
-
(2007)
Blood
, vol.109
, pp. 2579-2588
-
-
Isham, C.R.1
Tibodeau, J.D.2
Jin, W.3
Xu, R.4
Timm, M.M.5
Bible, K.C.6
-
286
-
-
70349464819
-
p21(WAF1) gene promoter is epigenetically silenced by CTIP2 and SUV39H1
-
Cherrier T, Suzanne S, Redel L, et al. p21(WAF1) gene promoter is epigenetically silenced by CTIP2 and SUV39H1. Oncogene 2009; 28: 3380-9.
-
(2009)
Oncogene
, vol.28
, pp. 3380-3389
-
-
Cherrier, T.1
Suzanne, S.2
Redel, L.3
-
287
-
-
75749102137
-
Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition
-
Lakshmikuttyamma A, Scott SA, DeCoteau JF, Geyer CR. Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition. Oncogene 2010; 29: 576-88.
-
(2010)
Oncogene
, vol.29
, pp. 576-588
-
-
Lakshmikuttyamma, A.1
Scott, S.A.2
Decoteau, J.F.3
Geyer, C.R.4
-
288
-
-
73149118652
-
Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes
-
Huang Y, Stewart TM, Wu Y, et al. Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes. Clin Cancer Res 2009; 15: 7217-28.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7217-7228
-
-
Huang, Y.1
Stewart, T.M.2
Wu, Y.3
-
289
-
-
34249934238
-
Inhibition of lysinespecific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes
-
Huang Y, Greene E, Murray Stewart T, et al. Inhibition of lysinespecific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes. Proc Natl Acad Sci U S A 2007; 104: 8023-8.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 8023-8028
-
-
Huang, Y.1
Greene, E.2
Murray Stewart, T.3
-
290
-
-
51349137876
-
Multi-targeted therapy of cancer by omega-3 fatty acids
-
Berquin IM, Edwards IJ, Chen YQ. Multi-targeted therapy of cancer by omega-3 fatty acids. Cancer Lett 2008; 269: 363-77.
-
(2008)
Cancer Lett
, vol.269
, pp. 363-377
-
-
Berquin, I.M.1
Edwards, I.J.2
Chen, Y.Q.3
-
291
-
-
77950889840
-
Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells
-
Dimri M, Bommi P, Sahasrabuddhe AA, Khandekar JD, Dimri GP. Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells. Carcinogenesis 2010; 31: 489-95.
-
(2010)
Carcinogenesis
, vol.31
, pp. 489-495
-
-
Dimri, M.1
Bommi, P.2
Sahasrabuddhe, A.A.3
Khandekar, J.D.4
Dimri, G.P.5
-
292
-
-
73949158230
-
n-3 Polyunsaturated fatty acids modulate carcinogen-directed non-coding microRNA signatures in rat colon
-
Davidson LA, Wang N, Shah MS, Lupton JR, Ivanov I, Chapkin RS. n-3 Polyunsaturated fatty acids modulate carcinogen-directed non-coding microRNA signatures in rat colon. Carcinogenesis 2009; 30: 2077-84.
-
(2009)
Carcinogenesis
, vol.30
, pp. 2077-2084
-
-
Davidson, L.A.1
Wang, N.2
Shah, M.S.3
Lupton, J.R.4
Ivanov, I.5
Chapkin, R.S.6
-
293
-
-
40249100742
-
Epigenetic regulation of telomerase in retinoid-induced differentiation of human leukemia cells
-
Love WK, Berletch JB, Andrews LG, Tollefsbol TO. Epigenetic regulation of telomerase in retinoid-induced differentiation of human leukemia cells. Int J Oncol 2008; 32: 625-31.
-
(2008)
Int J Oncol
, vol.32
, pp. 625-631
-
-
Love, W.K.1
Berletch, J.B.2
Andrews, L.G.3
Tollefsbol, T.O.4
-
294
-
-
0035000305
-
Transient vs. prolonged histone hyperacetylation: Effects on colon cancer cell growth, differentiation, and apoptosis
-
Wu JT, Archer SY, Hinnebusch B, Meng S, Hodin RA. Transient vs. prolonged histone hyperacetylation: effects on colon cancer cell growth, differentiation, and apoptosis. Am J Physiol Gastrointest Liver Physiol 2001; 280: G482-90.
-
(2001)
Am J Physiol Gastrointest Liver Physiol
, vol.280
-
-
Wu, J.T.1
Archer, S.Y.2
Hinnebusch, B.3
Meng, S.4
Hodin, R.A.5
-
295
-
-
4344666663
-
Histone deacetylase inhibitors upregulate death receptor 5/TRAIL-R2 and sensitize apoptosis induced by TRAIL/APO2-L in human malignant tumor cells
-
Nakata S, Yoshida T, Horinaka M, Shiraishi T, Wakada M, Sakai T. Histone deacetylase inhibitors upregulate death receptor 5/TRAIL-R2 and sensitize apoptosis induced by TRAIL/APO2-L in human malignant tumor cells. Oncogene 2004; 23: 6261-71.
-
(2004)
Oncogene
, vol.23
, pp. 6261-6271
-
-
Nakata, S.1
Yoshida, T.2
Horinaka, M.3
Shiraishi, T.4
Wakada, M.5
Sakai, T.6
-
296
-
-
32944462300
-
Rapid alteration of microRNA levels by histone deacetylase inhibition
-
Scott GK, Mattie MD, Berger CE, Benz SC, Benz CC. Rapid alteration of microRNA levels by histone deacetylase inhibition. Cancer Res 2006; 66: 1277-81.
-
(2006)
Cancer Res
, vol.66
, pp. 1277-1281
-
-
Scott, G.K.1
Mattie, M.D.2
Berger, C.E.3
Benz, S.C.4
Benz, C.C.5
-
297
-
-
76549087131
-
Lack of evidence for green tea polyphenols as DNA methylation inhibitors in murine prostate
-
Morey Kinney SR, Zhang W, Pascual M, et al. Lack of evidence for green tea polyphenols as DNA methylation inhibitors in murine prostate. Cancer Prev Res (Phila Pa) 2009; 2: 1065-75.
-
(2009)
Cancer Prev Res (Phila Pa)
, vol.2
, pp. 1065-1075
-
-
Morey Kinney, S.R.1
Zhang, W.2
Pascual, M.3
-
298
-
-
73749085369
-
The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells
-
Paluszczak J, Krajka-Kuzniak V, Baer-Dubowska W. The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells. Toxicol Lett 2010; 192: 119-25.
-
(2010)
Toxicol Lett
, vol.192
, pp. 119-125
-
-
Paluszczak, J.1
Krajka-Kuzniak, V.2
Baer-Dubowska, W.3
-
299
-
-
77953608981
-
Longterm genistein treatment of MCF-7 cells decreases acetylated histone 3 expression and alters growth responses to mitogens and histone deacetylase inhibitors
-
Jawaid K, Crane SR, Nowers JL, Lacey M, Whitehead SA. Longterm genistein treatment of MCF-7 cells decreases acetylated histone 3 expression and alters growth responses to mitogens and histone deacetylase inhibitors. J Steroid Biochem Mol Biol 2010; 120: 164-71.
-
(2010)
J Steroid Biochem Mol Biol
, vol.120
, pp. 164-171
-
-
Jawaid, K.1
Crane, S.R.2
Nowers, J.L.3
Lacey, M.4
Whitehead, S.A.5
-
300
-
-
34548071458
-
Mahanine reverses an epigenetically silenced tumor suppressor gene RASSF1A in human prostate cancer cells
-
Jagadeesh S, Sinha S, Pal BC, Bhattacharya S, Banerjee PP. Mahanine reverses an epigenetically silenced tumor suppressor gene RASSF1A in human prostate cancer cells. Biochem Biophys Res Commun 2007; 362: 212-7.
-
(2007)
Biochem Biophys Res Commun
, vol.362
, pp. 212-217
-
-
Jagadeesh, S.1
Sinha, S.2
Pal, B.C.3
Bhattacharya, S.4
Banerjee, P.P.5
-
301
-
-
0032905851
-
5-Aza-2'-deoxycytidine is chemopreventive in a 4-(methyl-nitrosamino)-1-(3-pyridyl)-1- butanone-induced primary mouse lung tumor model
-
Lantry LE, Zhang Z, Crist KA, et al. 5-Aza-2'-deoxycytidine is chemopreventive in a 4-(methyl-nitrosamino)-1-(3-pyridyl)-1- butanone-induced primary mouse lung tumor model. Carcinogenesis 1999; 20: 343-6.
-
(1999)
Carcinogenesis
, vol.20
, pp. 343-346
-
-
Lantry, L.E.1
Zhang, Z.2
Crist, K.A.3
-
302
-
-
0242442588
-
Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer
-
Belinsky SA, Klinge DM, Stidley CA, et al. Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer. Cancer Res 2003; 63: 7089-93.
-
(2003)
Cancer Res
, vol.63
, pp. 7089-7093
-
-
Belinsky, S.A.1
Klinge, D.M.2
Stidley, C.A.3
-
303
-
-
31544458225
-
Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer
-
McCabe MT, Low JA, Daignault S, Imperiale MJ, Wojno KJ, Day ML. Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer. Cancer Res 2006; 66: 385-92.
-
(2006)
Cancer Res
, vol.66
, pp. 385-392
-
-
McCabe, M.T.1
Low, J.A.2
Daignault, S.3
Imperiale, M.J.4
Wojno, K.J.5
Day, M.L.6
-
304
-
-
33644990380
-
Angiostatic activity of DNA methyltransferase inhibitors
-
Hellebrekers DM, Jair KW, Vire E, et al. Angiostatic activity of DNA methyltransferase inhibitors. Mol Cancer Ther 2006; 5: 467-75.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 467-475
-
-
Hellebrekers, D.M.1
Jair, K.W.2
Vire, E.3
-
305
-
-
30644474460
-
Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9
-
Greiner D, Bonaldi T, Eskeland R, Roemer E, Imhof A. Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9. Nat Chem Biol 2005; 1: 143-5.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 143-145
-
-
Greiner, D.1
Bonaldi, T.2
Eskeland, R.3
Roemer, E.4
Imhof, A.5
-
306
-
-
0038576158
-
The power and the promise of DNA methylation markers
-
Laird PW. The power and the promise of DNA methylation markers. Nat Rev Cancer 2003; 3: 253-66.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 253-266
-
-
Laird, P.W.1
-
307
-
-
0030742792
-
Arsenic alters cytosine methylation patterns of the promoter of the tumor suppressor gene p53 in human lung cells: A model for a mechanism of carcinogenesis
-
Mass MJ, Wang L. Arsenic alters cytosine methylation patterns of the promoter of the tumor suppressor gene p53 in human lung cells: a model for a mechanism of carcinogenesis. Mutat Res 1997; 386: 263-77.
-
(1997)
Mutat Res
, vol.386
, pp. 263-277
-
-
Mass, M.J.1
Wang, L.2
-
308
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A 1996; 93: 9821-6.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
309
-
-
0033556427
-
Extensive intra- and interindividual heterogeneity of p15INK4B methylation in acute myeloid leukemia
-
Aggerholm A, Guldberg P, Hokland M, Hokland P. Extensive intra- and interindividual heterogeneity of p15INK4B methylation in acute myeloid leukemia. Cancer Res 1999; 59: 436-41.
-
(1999)
Cancer Res
, vol.59
, pp. 436-441
-
-
Aggerholm, A.1
Guldberg, P.2
Hokland, M.3
Hokland, P.4
-
310
-
-
0034654669
-
MethyLight: A highthroughput assay to measure DNA methylation
-
Eads CA, Danenberg KD, Kawakami K, et al. MethyLight: a highthroughput assay to measure DNA methylation. Nucleic Acids Res 2000; 28: E32.
-
(2000)
Nucleic Acids Res
, vol.28
-
-
Eads, C.A.1
Danenberg, K.D.2
Kawakami, K.3
-
311
-
-
0030825309
-
COBRA: A sensitive and quantitative DNA methylation assay
-
Xiong Z, Laird PW. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res 1997; 25: 2532-4.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2532-2534
-
-
Xiong, Z.1
Laird, P.W.2
-
312
-
-
33947671871
-
Quantification of DNA methylation in electrofluidics chips (Bio-COBRA)
-
Brena RM, Auer H, Kornacker K, Plass C. Quantification of DNA methylation in electrofluidics chips (Bio-COBRA). Nat Protoc 2006; 1: 52-8.
-
(2006)
Nat Protoc
, vol.1
, pp. 52-58
-
-
Brena, R.M.1
Auer, H.2
Kornacker, K.3
Plass, C.4
-
313
-
-
0026546877
-
A genomic sequencing protocol that yields a positive display of 5- methylcytosine residues in individual DNA strands
-
Frommer M, McDonald LE, Millar DS, et al. A genomic sequencing protocol that yields a positive display of 5- methylcytosine residues in individual DNA strands. Proc Natl Acad Sci U S A 1992; 89: 1827-31.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 1827-1831
-
-
Frommer, M.1
McDonald, L.E.2
Millar, D.S.3
-
314
-
-
38449113853
-
DNA methylation analysis by pyrosequencing
-
Tost J, Gut IG. DNA methylation analysis by pyrosequencing. Nat Protoc 2007; 2: 2265-75.
-
(2007)
Nat Protoc
, vol.2
, pp. 2265-2275
-
-
Tost, J.1
Gut, I.G.2
-
315
-
-
0036314920
-
Quantitative methylation analysis using methylation-sensitive single-nucleotide primer extension (Ms- SNuPE)
-
Gonzalgo ML, Jones PA. Quantitative methylation analysis using methylation-sensitive single-nucleotide primer extension (Ms- SNuPE). Methods 2002; 27: 128-33.
-
(2002)
Methods
, vol.27
, pp. 128-133
-
-
Gonzalgo, M.L.1
Jones, P.A.2
-
316
-
-
73449102901
-
Qualitative and quantitative genotyping using single base primer extension coupled with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MassARRAY)
-
Oeth P, del Mistro G, Marnellos G, Shi T, van den Boom D. Qualitative and quantitative genotyping using single base primer extension coupled with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MassARRAY). Methods Mol Biol 2009; 578: 307-43.
-
(2009)
Methods Mol Biol
, vol.578
, pp. 307-343
-
-
Oeth, P.1
del Mistro, G.2
Marnellos, G.3
Shi, T.4
van den Boom, D.5
-
317
-
-
27644548948
-
Quantitative highthroughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry
-
Ehrich M, Nelson MR, Stanssens P, et al. Quantitative highthroughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry. Proc Natl Acad Sci U S A 2005; 102: 15785-90.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15785-15790
-
-
Ehrich, M.1
Nelson, M.R.2
Stanssens, P.3
-
318
-
-
34547476585
-
Global, comparative analysis of tissuespecific promoter CpG methylation
-
Schilling E, Rehli M. Global, comparative analysis of tissuespecific promoter CpG methylation. Genomics 2007; 90: 314-23.
-
(2007)
Genomics
, vol.90
, pp. 314-323
-
-
Schilling, E.1
Rehli, M.2
-
319
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber M, Hellmann I, Stadler MB, et al. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 2007; 39: 457-66.
-
(2007)
Nat Genet
, vol.39
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
-
320
-
-
33746756014
-
Comparative isoschizomer profiling of cytosine methylation: The HELP assay
-
Khulan B, Thompson RF, Ye K, et al. Comparative isoschizomer profiling of cytosine methylation: the HELP assay. Genome Res 2006; 16: 1046-55.
-
(2006)
Genome Res
, vol.16
, pp. 1046-1055
-
-
Khulan, B.1
Thompson, R.F.2
Ye, K.3
-
321
-
-
0030888263
-
Identification of DNA methylation markers for human breast carcinomas using the methylation-sensitive restriction fingerprinting technique
-
Huang TH, Laux DE, Hamlin BC, Tran P, Tran H, Lubahn DB. Identification of DNA methylation markers for human breast carcinomas using the methylation-sensitive restriction fingerprinting technique. Cancer Res 1997; 57: 1030-4.
-
(1997)
Cancer Res
, vol.57
, pp. 1030-1034
-
-
Huang, T.H.1
Laux, D.E.2
Hamlin, B.C.3
Tran, P.4
Tran, H.5
Lubahn, D.B.6
-
322
-
-
34247136384
-
Techniques used in studies of epigenome dysregulation due to aberrant DNA methylation: An emphasis on fetal-based adult diseases
-
Ho SM, Tang WY. Techniques used in studies of epigenome dysregulation due to aberrant DNA methylation: an emphasis on fetal-based adult diseases. Reprod Toxicol 2007; 23: 267-82.
-
(2007)
Reprod Toxicol
, vol.23
, pp. 267-282
-
-
Ho, S.M.1
Tang, W.Y.2
-
323
-
-
0036322489
-
Applications of CpG island microarrays for high-throughput analysis of DNA methylation
-
Yan PS, Chen CM, Shi H, Rahmatpanah F, Wei SH, Huang TH. Applications of CpG island microarrays for high-throughput analysis of DNA methylation. J Nutr 2002; 132: 2430S-34S.
-
(2002)
J Nutr
, vol.132
-
-
Yan, P.S.1
Chen, C.M.2
Shi, H.3
Rahmatpanah, F.4
Wei, S.H.5
Huang, T.H.6
-
324
-
-
34250782684
-
Extraction, purification and analysis of histones
-
Shechter D, Dormann HL, Allis CD, Hake SB. Extraction, purification and analysis of histones. Nat Protoc 2007; 2: 1445-57.
-
(2007)
Nat Protoc
, vol.2
, pp. 1445-1457
-
-
Shechter, D.1
Dormann, H.L.2
Allis, C.D.3
Hake, S.B.4
-
325
-
-
20444444649
-
Mechanism of human SIRT1 activation by resveratrol
-
Borra MT, Smith BC, Denu JM. Mechanism of human SIRT1 activation by resveratrol. J Biol Chem 2005; 280: 17187-95.
-
(2005)
J Biol Chem
, vol.280
, pp. 17187-17195
-
-
Borra, M.T.1
Smith, B.C.2
Denu, J.M.3
-
326
-
-
0000032126
-
Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase
-
Kwon HJ, Owa T, Hassig CA, Shimada J, Schreiber SL. Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase. Proc Natl Acad Sci U S A 1998; 95: 3356-61.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 3356-3361
-
-
Kwon, H.J.1
Owa, T.2
Hassig, C.A.3
Shimada, J.4
Schreiber, S.L.5
-
327
-
-
0033714888
-
HATs off: Selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF
-
Lau OD, Kundu TK, Soccio RE, et al. HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF. Mol Cell 2000; 5: 589-95.
-
(2000)
Mol Cell
, vol.5
, pp. 589-595
-
-
Lau, O.D.1
Kundu, T.K.2
Soccio, R.E.3
-
328
-
-
0035694922
-
Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase
-
Wang H, Cao R, Xia L, et al. Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase. Mol Cell 2001; 8: 1207-17.
-
(2001)
Mol Cell
, vol.8
, pp. 1207-1217
-
-
Wang, H.1
Cao, R.2
Xia, L.3
-
329
-
-
38749142157
-
Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies
-
Zhang X, Guo C, Chen Y, et al. Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies. Nat Methods 2008; 5: 163-5.
-
(2008)
Nat Methods
, vol.5
, pp. 163-165
-
-
Zhang, X.1
Guo, C.2
Chen, Y.3
-
330
-
-
50849090969
-
Genome-wide analysis of transcription factor binding sites based on ChIP-Seq data
-
Valouev A, Johnson DS, Sundquist A, et al. Genome-wide analysis of transcription factor binding sites based on ChIP-Seq data. Nat Methods 2008; 5: 829-34.
-
(2008)
Nat Methods
, vol.5
, pp. 829-834
-
-
Valouev, A.1
Johnson, D.S.2
Sundquist, A.3
-
331
-
-
22144486551
-
Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1
-
Carroll JS, Liu XS, Brodsky AS, et al. Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell 2005; 122: 33-43.
-
(2005)
Cell
, vol.122
, pp. 33-43
-
-
Carroll, J.S.1
Liu, X.S.2
Brodsky, A.S.3
-
332
-
-
45549091261
-
OSU-HDAC42, a histone deacetylase inhibitor, blocks prostate tumor progression in the transgenic adenocarcinoma of the mouse prostate model
-
Sargeant AM, Rengel RC, Kulp SK, et al. OSU-HDAC42, a histone deacetylase inhibitor, blocks prostate tumor progression in the transgenic adenocarcinoma of the mouse prostate model. Cancer Res 2008; 68: 3999-4009.
-
(2008)
Cancer Res
, vol.68
, pp. 3999-4009
-
-
Sargeant, A.M.1
Rengel, R.C.2
Kulp, S.K.3
|