Kinetic basis for the differing response to an oxidative lesion by a replicative and a lesion bypass DNA polymerase from Sulfolobus solfataricus

Biochemistry

Volumn 51, Issue 16, 2012, Pages 3485-3496

  Maxwell, Brian A ^a   Suo, Zucai ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASE PAIRS; DNA LESIONS; DNA POLYMERASE; DNA REPLICATIONS; DNA SUBSTRATES; EXONUCLEASE ACTIVITY; GENOMIC MUTATION; HIGH TEMPERATURE; HYPERTHERMOPHILES; HYPERTHERMOPHILIC; LESION BYPASS; LESION SITE; OXIDATIVE DAMAGE; POLYMERASE ACTIVITIES; PRE-STEADY STATE; REPLICATION FORK; SULFOLOBUS SOLFATARICUS; SWITCHING MECHANISM;

KINETICS; NUCLEOTIDES; POLYMERS;

DNA;

8 HYDROXYGUANINE; DNA DIRECTED DNA POLYMERASE BETA; DNA POLYMERASE; EXONUCLEASE; NUCLEOTIDE;

ARTICLE; BASE PAIRING; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; ENZYME ACTIVITY; HYPERTHERMOPHILIC ARCHAEON; KINETICS; NONHUMAN; PRIORITY JOURNAL; STEADY STATE; SULFOLOBUS SOLFATARICUS; WILD TYPE;

ARCHAEAL PROTEINS; BASE PAIRING; BASE SEQUENCE; DNA; DNA DAMAGE; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; GUANINE; KINETICS; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; SULFOLOBUS SOLFATARICUS;

EID: 84860189814     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300246r     Document Type: Article

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