DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 703, Issue 1, 2010, Pages 18-23

  Beard, William A ^a   Batra, Vinod K ^a   Wilson, Samuel H ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Base excision repair; DNA polymerase; Endogenous DNA damage; Fidelity; Structure

Indexed keywords

8 HYDROXYGUANINE; ADENINE; CYTOSINE; DNA DIRECTED DNA POLYMERASE BETA;

BASE PAIRING; DNA DAMAGE; DNA SYNTHESIS; DNA TEMPLATE; ENZYME STRUCTURE; HYDROGEN BOND; MUTAGENICITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CONFORMATION; REVIEW;

ANIMALS; DNA DAMAGE; DNA POLYMERASE BETA; DNA REPAIR; DNA REPAIR ENZYMES; DNA-DIRECTED DNA POLYMERASE; GUANINE; HUMANS; MODELS, MOLECULAR; MUTAGENS; OXIDATIVE STRESS; PHOSPHORIC MONOESTER HYDROLASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78549267771     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2010.07.013     Document Type: Review

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