Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase

Nature

Volumn 431, Issue 7005, 2004, Pages 217-221

  Hsu, Gerald W ^a   Ober, Matthias ^b   Carell, Thomas ^b   Beese, Lorena S ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; ENZYMES; GENES; OXIDATION; OXYGEN; TUMORS;

ADENINE; AEROBIC RESPIRATION; MISMATCH RECOGNITION; REACTIVE OXYGEN SPECIES;

DNA;

8 HYDROXYDEOXYGUANOSINE; DNA POLYMERASE;

BIOLOGY; DNA;

ACCURACY; ARTICLE; BASE MISPAIRING; CRYSTAL STRUCTURE; DNA DAMAGE; DNA REPLICATION; GENE MUTATION; MISMATCH REPAIR; MUTAGENESIS; PRIORITY JOURNAL;

BASE PAIRING; BASE SEQUENCE; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DNA; DNA DAMAGE; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; GUANOSINE; KINETICS; MODELS, MOLECULAR; MUTAGENESIS; OXIDATION-REDUCTION; OXIDATIVE STRESS; SUBSTRATE SPECIFICITY;

EID: 4544273926     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02908     Document Type: Article

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