Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase

EMBO Journal

Volumn 23, Issue 17, 2004, Pages 3452-3461

  Brieba, Luis G ^a   Eichman, Brandt F ^a   Kokoska, Robert J ^b   Doublié, Sylvia ^a,c   Kunkel, Tom A ^b   Ellenberger, Tom ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

DNA damage; DNA polymerase; Protein crystallography; Replication fidelity

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; DEOXYADENOSINE TRIPHOSPHATE; DNA POLYMERASE;

ARTICLE; CRYSTAL STRUCTURE; DNA DAMAGE; DNA REPLICATION; ENZYME CONFORMATION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; X RAY CRYSTALLOGRAPHY;

BACTERIOPHAGE T7; BASE PAIR MISMATCH; BASE PAIRING; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DEOXYADENINE NUCLEOTIDES; DEOXYCYTIDINE; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; ELECTROSTATICS; GUANOSINE; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; RECOMBINANT PROTEINS;

INSERTION SEQUENCES;

EID: 4644259458     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600354     Document Type: Article

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