Mechanism of Template-independent Nucleotide Incorporation Catalyzed by a Template-dependent DNA Polymerase

Journal of Molecular Biology

Volumn 365, Issue 3, 2007, Pages 590-602

  Fiala, Kevin A ^a   Brown, Jessica A ^a   Ling, Hong ^b   Kshetry, Ajay K ^c   Zhang, Jun ^a   Taylor, John Stephen ^c   Yang, Wei ^d   Suo, Zucai ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c WASHINGTON UNIVERSITY   (United States)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

blunt end addition; Dpo4; pre steady state kinetics; pyrene nucleoside 5 triphosphate; X ray crystal structure

Indexed keywords

2',3' DIDEOXYADENOSINE TRIPHOSPHATE; DEOXYADENOSINE PHOSPHATE; DEOXYADENOSINE TRIPHOSPHATE; DEOXYRIBONUCLEOTIDE; DNA; DNA POLYMERASE; NUCLEOSIDE TRIPHOSPHATE; NUCLEOTIDE DERIVATIVE; PROTEIN DPO4; PYRENE DERIVATIVE;

ARTICLE; BASE PAIRING; BINDING AFFINITY; CONTROLLED STUDY; DNA SYNTHESIS; DNA TEMPLATE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; HUMAN IMMUNODEFICIENCY VIRUS; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; RETROVIRUS; SULFOLOBUS SOLFATARICUS; X RAY CRYSTALLOGRAPHY;

HUMAN IMMUNODEFICIENCY VIRUS; SULFOLOBUS SOLFATARICUS;

EID: 33845638804     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.10.008     Document Type: Article

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