DNA lesion alters global conformational dynamics of Y-family DNA polymerase during catalysis

Journal of Biological Chemistry

Volumn 287, Issue 16, 2012, Pages 13040-13047

  Maxwell, Brian A ^a   Xu, Cuiling ^a   Suo, Zucai ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONAL DYNAMICS; CONFORMATIONAL TRANSITIONS; DNA LESIONS; DNA POLYMERASE; GENOMIC MUTATION; IN-VIVO; KINETIC STUDY; NUCLEOTIDE BINDING; OXIDATIVE DAMAGE; STOPPED FLOW; SULFOLOBUS SOLFATARICUS;

DYNAMICS; NUCLEOTIDES; POLYMERS;

DNA;

8 HYDROXYDEOXYGUANOSINE; DNA POLYMERASE; NUCLEOTIDE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DNA BINDING; DNA DAMAGE; ENZYME CONFORMATION; ENZYME KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SULFOLOBUS SOLFATARICUS;

BACTERIAL PROTEINS; CATALYSIS; DNA DAMAGE; DNA POLYMERASE BETA; DNA, BACTERIAL; FLUORESCENCE RESONANCE ENERGY TRANSFER; GUANINE; OXIDATIVE STRESS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SULFOLOBUS SOLFATARICUS;

SULFOLOBUS SOLFATARICUS;

EID: 84859765696     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.345835     Document Type: Article

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