-
1
-
-
0023696960
-
Recent Studies on the Fidelity of DNA Synthesis
-
Kunkel, T. A., and Bebenek, K. (1988) Recent Studies on the Fidelity of DNA Synthesis. Biochim. Biophys. Acta 951, 1-15.
-
(1988)
Biochim. Biophys. Acta
, vol.951
, pp. 1-15
-
-
Kunkel, T.A.1
Bebenek, K.2
-
2
-
-
34548527840
-
Studies on the Replication of the Ring-Opened Formamidopyrimidines, Fapy·dG in Escherichia coli
-
Patro, J. N., Wiederholt, C. J., Jiang, Y. L., Delaney, J. C., Essigmann, J. M., and Greenberg, M. M. (2007) Studies on the Replication of the Ring-Opened Formamidopyrimidines, Fapy·dG in Escherichia coli. Biochemistry 46, 10202-10212.
-
(2007)
Biochemistry
, vol.46
, pp. 10202-10212
-
-
Patro, J.N.1
Wiederholt, C.J.2
Jiang, Y.L.3
Delaney, J.C.4
Essigmann, J.M.5
Greenberg, M.M.6
-
3
-
-
33750968484
-
Synthesis, DNA Polymerase Incorporation, and Enzymatic Phosphate Hydrolysis of Formamidopyrimidine Nucleoside Triphosphates
-
Imoto, S., Patro, J. N., Jiang, Y. L., and Greenberg, M. M. (2006) Synthesis, DNA Polymerase Incorporation, and Enzymatic Phosphate Hydrolysis of Formamidopyrimidine Nucleoside Triphosphates. J. Am. Chem. Soc. 128, 14606-14611.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 14606-14611
-
-
Imoto, S.1
Patro, J.N.2
Jiang, Y.L.3
Greenberg, M.M.4
-
4
-
-
0032558424
-
Steady-State and Pre-Steady-State Kinetic Analysis of 8-Oxo-7,8-dihydroguanosine Triphosphate Incorporation and Extension by Replicative and Repair DNA Polymerases
-
Einolf, H. J., Schnetz-Boutaud, N., and Guengerich, F. P. (1998) Steady-State and Pre-Steady-State Kinetic Analysis of 8-Oxo-7,8-dihydroguanosine Triphosphate Incorporation and Extension by Replicative and Repair DNA Polymerases. Biochemistry 37, 13300-13312.
-
(1998)
Biochemistry
, vol.37
, pp. 13300-13312
-
-
Einolf, H.J.1
Schnetz-Boutaud, N.2
Guengerich, F.P.3
-
6
-
-
33846300306
-
Human DNA Polymerase α Uses a Combination of Positive and negative Selectivity to Polymerize Purine dNTPs with High Fidelity
-
Beckman, J., Kincaid, K., Hocek, M., Spratt, T., Engels, J., Cosstick, R., and Kuchta, R. D. (2007) Human DNA Polymerase α Uses a Combination of Positive and negative Selectivity to Polymerize Purine dNTPs with High Fidelity. Biochemistry 46, 448-460.
-
(2007)
Biochemistry
, vol.46
, pp. 448-460
-
-
Beckman, J.1
Kincaid, K.2
Hocek, M.3
Spratt, T.4
Engels, J.5
Cosstick, R.6
Kuchta, R.D.7
-
7
-
-
33746312883
-
Remarkable Sensitivity to DNA Base Shape in the DNA Polymerase Active Site
-
Sintim, H. O., and Kool, E. T. (2006) Remarkable Sensitivity to DNA Base Shape in the DNA Polymerase Active Site. Angew. Chem., Int. Ed. 45, 1974-1979.
-
(2006)
Angew. Chem., Int. Ed
, vol.45
, pp. 1974-1979
-
-
Sintim, H.O.1
Kool, E.T.2
-
8
-
-
18744364740
-
Exploration of Factors Driving Incorporation of Unnatural dNTPs into DNA by Klenow Fragment (DNA Polymerase I) and DNA Polymerase α
-
Kincaid, K., Beckman, J., Zivkovic, A., Halcomb, R. L., Engels, J. W., and Kuchta, R. D. (2005) Exploration of Factors Driving Incorporation of Unnatural dNTPs into DNA by Klenow Fragment (DNA Polymerase I) and DNA Polymerase α. Nucleic Acids Res. 33, 2620-2628.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 2620-2628
-
-
Kincaid, K.1
Beckman, J.2
Zivkovic, A.3
Halcomb, R.L.4
Engels, J.W.5
Kuchta, R.D.6
-
9
-
-
0042318450
-
Facile Polymerization of dNTPs Bearing Unnatural Base Analogues by DNA Polymerase α and Klenow Fragment (DNA Polymerase I)
-
Chiaramonte, M., Moore, C. L., Kincaid, K., and Kuchta, R. D. (2003) Facile Polymerization of dNTPs Bearing Unnatural Base Analogues by DNA Polymerase α and Klenow Fragment (DNA Polymerase I). Biochemistry 42, 10472-10481.
-
(2003)
Biochemistry
, vol.42
, pp. 10472-10481
-
-
Chiaramonte, M.1
Moore, C.L.2
Kincaid, K.3
Kuchta, R.D.4
-
10
-
-
0031027125
-
How Easily Oxidizable is DNA? One-Electron Reduction Potentials of Adenosine and Guanosine Radicals in Aqueous Solution
-
Steenken, S., and Jovanovic, S. V. (1997) How Easily Oxidizable is DNA? One-Electron Reduction Potentials of Adenosine and Guanosine Radicals in Aqueous Solution. J. Am. Chem. Soc. 119, 617-618.
-
(1997)
J. Am. Chem. Soc
, vol.119
, pp. 617-618
-
-
Steenken, S.1
Jovanovic, S.V.2
-
11
-
-
0032565577
-
Mutagenicity and Repair of Oxidative DNA Damage: Insights from Studies Using Defined Lesions
-
Wang, D., Kreutzer, D. A., and Essigmann, J. M. (1998) Mutagenicity and Repair of Oxidative DNA Damage: Insights from Studies Using Defined Lesions. Mutat. Res. 400, 99-115.
-
(1998)
Mutat. Res
, vol.400
, pp. 99-115
-
-
Wang, D.1
Kreutzer, D.A.2
Essigmann, J.M.3
-
12
-
-
33745485302
-
Mutagenesis and Carcinogenesis Caused by the Oxidation of Nucleic Acids
-
Nakabeppu, Y., Sakumi, K., Sakamoto, K., Tsuchimoto, D., Tsuzuki, T., and Nakatsu, Y. (2006) Mutagenesis and Carcinogenesis Caused by the Oxidation of Nucleic Acids. Biol. Chem. 387, 373-379.
-
(2006)
Biol. Chem
, vol.387
, pp. 373-379
-
-
Nakabeppu, Y.1
Sakumi, K.2
Sakamoto, K.3
Tsuchimoto, D.4
Tsuzuki, T.5
Nakatsu, Y.6
-
13
-
-
0025891866
-
NMR Structural Studies of the Ionizing Radiation Adduct 7-Hydro-8-oxodeoxyguanosine (8-oxo-7H-dG) Opposite Deoxyadenosine in a DNA Duplex. 8-Oxo-7H-dG(syn)·dA(anti) Alignment at Lesion Site
-
Kouchakdjian, M., Bodepudi, V., Shibutani, S., Eisenberg, M., Johnson, F., Grollman, A. P., and Patel, D. J. (1991) NMR Structural Studies of the Ionizing Radiation Adduct 7-Hydro-8-oxodeoxyguanosine (8-oxo-7H-dG) Opposite Deoxyadenosine in a DNA Duplex. 8-Oxo-7H-dG(syn)·dA(anti) Alignment at Lesion Site. Biochemistry 30, 1403-1412.
-
(1991)
Biochemistry
, vol.30
, pp. 1403-1412
-
-
Kouchakdjian, M.1
Bodepudi, V.2
Shibutani, S.3
Eisenberg, M.4
Johnson, F.5
Grollman, A.P.6
Patel, D.J.7
-
14
-
-
0028799524
-
X-ray Structure of a DNA Decamer Containing 7,8-Dihydro-8-oxoguanine
-
Lipscomb, L. A., Peek, M. E., Morningstar, M. L., Verghis, S. M., Miller, E. M., Rich, A., Essigmann, J. M., and Williams, L. D. (1995) X-ray Structure of a DNA Decamer Containing 7,8-Dihydro-8-oxoguanine. Proc. Natl. Acad. Sci. U.S.A. 92, 719-723.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A
, vol.92
, pp. 719-723
-
-
Lipscomb, L.A.1
Peek, M.E.2
Morningstar, M.L.3
Verghis, S.M.4
Miller, E.M.5
Rich, A.6
Essigmann, J.M.7
Williams, L.D.8
-
15
-
-
0037154121
-
Oxidation of 7,8-Dihydro-8-oxoguanine Affords Lesions That Are Potent Sources of Replication Errors in Vivo
-
Henderson, P. T., Delaney, J. C., Gu, F., Tannenbaum, S. R., and Essigmann, J. M. (2002) Oxidation of 7,8-Dihydro-8-oxoguanine Affords Lesions That Are Potent Sources of Replication Errors in Vivo. Biochemistry 41, 914-921.
-
(2002)
Biochemistry
, vol.41
, pp. 914-921
-
-
Henderson, P.T.1
Delaney, J.C.2
Gu, F.3
Tannenbaum, S.R.4
Essigmann, J.M.5
-
16
-
-
0026592966
-
8-Hydroxyguanine, an Abundant Form of Oxidative DNA Damage, Causes G→T and A→C Substitutions
-
Cheng, K. C., Cahill, D. S., Kasai, H., Nishimura, S., and Loeb, L. (1992) 8-Hydroxyguanine, an Abundant Form of Oxidative DNA Damage, Causes G→T and A→C Substitutions. J. Biol. Chem. 267, 166-172.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 166-172
-
-
Cheng, K.C.1
Cahill, D.S.2
Kasai, H.3
Nishimura, S.4
Loeb, L.5
-
17
-
-
0037013297
-
Assessing the Metabolic Function of the Mut T 8-Oxodeoxyguanosine Triphosphatase in Escherichia coli by Nucleotide Pool Analysis
-
Tassotto, M. L., and Mathews, C. K. (2002) Assessing the Metabolic Function of the Mut T 8-Oxodeoxyguanosine Triphosphatase in Escherichia coli by Nucleotide Pool Analysis. J. Biol. Chem. 277, 15807-15812.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 15807-15812
-
-
Tassotto, M.L.1
Mathews, C.K.2
-
18
-
-
33847007529
-
The mechanics of base excision repair, and its relationship to aging and disease
-
Wilson, D. M., and Bohr, V. A. (2007) The mechanics of base excision repair, and its relationship to aging and disease. DNA Repair 6, 544-559.
-
(2007)
DNA Repair
, vol.6
, pp. 544-559
-
-
Wilson, D.M.1
Bohr, V.A.2
-
19
-
-
0034320671
-
Mono- and Bifunctional DNA Glycosylases Involved in Repairing Oxidatively Damaged DNA
-
Kuznetsova, S. A., and Rykhlevskaya, A. I. (2000) Mono- and Bifunctional DNA Glycosylases Involved in Repairing Oxidatively Damaged DNA. Mol. Biol. 34, 860-874.
-
(2000)
Mol. Biol
, vol.34
, pp. 860-874
-
-
Kuznetsova, S.A.1
Rykhlevskaya, A.I.2
-
20
-
-
0025981359
-
Insertion of Specific Bases During DNA Synthesis Past the Oxidative-Damaged Base 8-Oxo dG
-
Shibutani, S., Takeshita, M., and Grollman, A. P. (1991) Insertion of Specific Bases During DNA Synthesis Past the Oxidative-Damaged Base 8-Oxo dG. Nature 349, 431-432.
-
(1991)
Nature
, vol.349
, pp. 431-432
-
-
Shibutani, S.1
Takeshita, M.2
Grollman, A.P.3
-
21
-
-
34548570175
-
A Highly Conserved Tyrosine Residue of Family B DNA Polymerase Contributes to Dictate Translesion Synthesis Past 8-Oxo-7,8-dihydro-2′-deoxyguanosine
-
de Vega, M., and Salas, M. (2007) A Highly Conserved Tyrosine Residue of Family B DNA Polymerase Contributes to Dictate Translesion Synthesis Past 8-Oxo-7,8-dihydro-2′-deoxyguanosine. Nucleic Acids Res. 35, 5096-5107.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 5096-5107
-
-
de Vega, M.1
Salas, M.2
-
22
-
-
2342484512
-
Lesion (In)tolerance Reveals Insights into DNA Replication Fidelity
-
Freisinger, E., Grollman, A. P., Miller, H., and Kisker, C. (2004) Lesion (In)tolerance Reveals Insights into DNA Replication Fidelity. EMBO J. 23, 1494-1505.
-
(2004)
EMBO J
, vol.23
, pp. 1494-1505
-
-
Freisinger, E.1
Grollman, A.P.2
Miller, H.3
Kisker, C.4
-
23
-
-
0026727870
-
Conformation of Guanine-8-Oxoadenine Base Pairs in the Crystal Structure of d(CGCGAATT(O8A)GCG
-
Leonard, G. A., Guy, A., Brown, T., Teoule, R., and Hunter, W. N. (1992) Conformation of Guanine-8-Oxoadenine Base Pairs in the Crystal Structure of d(CGCGAATT(O8A)GCG. Biochemistry 31, 8415-8420.
-
(1992)
Biochemistry
, vol.31
, pp. 8415-8420
-
-
Leonard, G.A.1
Guy, A.2
Brown, T.3
Teoule, R.4
Hunter, W.N.5
-
24
-
-
0027930608
-
Crystal Structure of a DNA Duplex Containing 8-Hydroxydeoxyguanine-Adenine Base Pairs
-
McAuley-Hecht, K. E., Leonard, G. A., Gibson, N. J., Thomson, J. B., Watson, W. P., Hunter, W. N., and Brown, T. (1994) Crystal Structure of a DNA Duplex Containing 8-Hydroxydeoxyguanine-Adenine Base Pairs. Biochemistry 33, 10266-10270.
-
(1994)
Biochemistry
, vol.33
, pp. 10266-10270
-
-
McAuley-Hecht, K.E.1
Leonard, G.A.2
Gibson, N.J.3
Thomson, J.B.4
Watson, W.P.5
Hunter, W.N.6
Brown, T.7
-
25
-
-
4544273926
-
Error-Prone Replication of Oxidatively Damaged DNA by a High-Fidelity DNA Polymerase
-
Hsu, G. W., Ober, M., Carell, T., and Beese, L. S. (2004) Error-Prone Replication of Oxidatively Damaged DNA by a High-Fidelity DNA Polymerase. Nature 431, 217-221.
-
(2004)
Nature
, vol.431
, pp. 217-221
-
-
Hsu, G.W.1
Ober, M.2
Carell, T.3
Beese, L.S.4
-
26
-
-
43849111224
-
Lesion Processing: High-Fidelity versus Lesion-Bypass DNA Polymerases
-
Broyde, S., Wang, L., Rechkoblit, O., Geacintov, N. E., and Patel, D. J. (2008) Lesion Processing: High-Fidelity versus Lesion-Bypass DNA Polymerases. Trends Biochem. Sci. 33, 209-219.
-
(2008)
Trends Biochem. Sci
, vol.33
, pp. 209-219
-
-
Broyde, S.1
Wang, L.2
Rechkoblit, O.3
Geacintov, N.E.4
Patel, D.J.5
-
27
-
-
58549090909
-
Role of the 2-Amino Group of Purines during dNTP Polymerization by Human DNA Polymerase a
-
Patro, J. N., Urban, M., and Kuchta, R. D. (2009) Role of the 2-Amino Group of Purines during dNTP Polymerization by Human DNA Polymerase a. Biochemistry 48, 180-189.
-
(2009)
Biochemistry
, vol.48
, pp. 180-189
-
-
Patro, J.N.1
Urban, M.2
Kuchta, R.D.3
-
28
-
-
66349091016
-
Discrimination between Right and Wrong Purine dNTPs by DNA Polymerase I from Bacillus stearothermophilus
-
Trostler, M., Delier, A., Beckman, J., Urban, M., Patro, J. N., Spratt, T. E., Beese, L. S., and Kuchta, R. D. (2009) Discrimination between Right and Wrong Purine dNTPs by DNA Polymerase I from Bacillus stearothermophilus. Biochemistry 48, 4633-4641.
-
(2009)
Biochemistry
, vol.48
, pp. 4633-4641
-
-
Trostler, M.1
Delier, A.2
Beckman, J.3
Urban, M.4
Patro, J.N.5
Spratt, T.E.6
Beese, L.S.7
Kuchta, R.D.8
-
29
-
-
0033613106
-
Abasic Template Lesions are Strong Chain Terminators for DNA Primase but not for DNA Polymerase Alpha During Synthesis of new DNA Strands
-
Zerbe, L. K., Goodman, M. F., Efrati, E., and Kuchta, R. D. (1999) Abasic Template Lesions are Strong Chain Terminators for DNA Primase but not for DNA Polymerase Alpha During Synthesis of new DNA Strands. Biochemistry 38, 12908-12914.
-
(1999)
Biochemistry
, vol.38
, pp. 12908-12914
-
-
Zerbe, L.K.1
Goodman, M.F.2
Efrati, E.3
Kuchta, R.D.4
-
30
-
-
59449102872
-
Initiation of New DNA Strands by the Herpes Simplex Virus-1 Primase-Helicase Complex and Either Herpes DNA Polymerase or Human DNA Polymerase
-
Cavanaugh, N., and Kuchta, R. D. (2009) Initiation of New DNA Strands by the Herpes Simplex Virus-1 Primase-Helicase Complex and Either Herpes DNA Polymerase or Human DNA Polymerase. J. Biol. Chem. 284, 1523-1532.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 1523-1532
-
-
Cavanaugh, N.1
Kuchta, R.D.2
-
31
-
-
0023657032
-
Kinetic Mechanism of DNA Polymerase I (Klenow)
-
Kuchta, R. D., Mizrahi, V., Benkovic, P. A., Johnson, K. A., and Benkovic, S. J. (1989) Kinetic Mechanism of DNA Polymerase I (Klenow). Biochemistry 26, 8410-8417.
-
(1989)
Biochemistry
, vol.26
, pp. 8410-8417
-
-
Kuchta, R.D.1
Mizrahi, V.2
Benkovic, P.A.3
Johnson, K.A.4
Benkovic, S.J.5
-
32
-
-
0004136246
-
-
Cold Spring Harbor Laboratories, Cold Spring Harbor, NY
-
Sambrook, J., Fritsch, E. F., Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual , Cold Spring Harbor Laboratories, Cold Spring Harbor, NY.
-
(1989)
Molecular Cloning: A Laboratory Manual
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
33
-
-
49149135789
-
Deoxunucleoside Phosphoramidites - A New Class of Key Intermediates for Deoxypolynucleotide Synthesis
-
Beaucage, S. L., and Caruthers, M. H. (1981) Deoxunucleoside Phosphoramidites - A New Class of Key Intermediates for Deoxypolynucleotide Synthesis. Tet. Lett. 22, 1859-1862.
-
(1981)
Tet. Lett
, vol.22
, pp. 1859-1862
-
-
Beaucage, S.L.1
Caruthers, M.H.2
-
34
-
-
7144238770
-
An Investigation of Several Deoxynucleoside Phosphoramidites Useful for Synthesizing Deoxynucleotides
-
McBride, L. J., and Caruthers, M. H. (1983) An Investigation of Several Deoxynucleoside Phosphoramidites Useful for Synthesizing Deoxynucleotides. Tetrahedrom Lett. 24, 245-248.
-
(1983)
Tetrahedrom Lett
, vol.24
, pp. 245-248
-
-
McBride, L.J.1
Caruthers, M.H.2
-
35
-
-
0031861823
-
Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates
-
Li, Y., Kong, Y., Korolev, S., and Waksman, G. (1998) Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates. Protein Sci. 7, 1116-1123.
-
(1998)
Protein Sci
, vol.7
, pp. 1116-1123
-
-
Li, Y.1
Kong, Y.2
Korolev, S.3
Waksman, G.4
-
36
-
-
35349009532
-
A Pre-equilibrium before Nucleotide Binding Limits Fingers Subdomain Closure by Klentaq1
-
Rothwell, P. J., and Waksman, G. (2007) A Pre-equilibrium before Nucleotide Binding Limits Fingers Subdomain Closure by Klentaq1. J. Biol. Chem. 282, 28884-28892.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 28884-28892
-
-
Rothwell, P.J.1
Waksman, G.2
-
37
-
-
0028983795
-
Crystal structure of Thermus aquaticus DNA polymerase
-
Kim, Y., Eom, S. H., Wang, J., Lee, D.-S., Suh, S. W., and Steitz, T. A. (1995) Crystal structure of Thermus aquaticus DNA polymerase. Nature 376, 612-616.
-
(1995)
Nature
, vol.376
, pp. 612-616
-
-
Kim, Y.1
Eom, S.H.2
Wang, J.3
Lee, D.-S.4
Suh, S.W.5
Steitz, T.A.6
-
38
-
-
33846011884
-
Incorporation and Replication of 8-Oxo-deoxyguanosine by the Human Mitochondrial DNA Polymerase
-
Hanes, J. W., Thai, D. M., and Johnson, K. A. (2006) Incorporation and Replication of 8-Oxo-deoxyguanosine by the Human Mitochondrial DNA Polymerase. J. Biol. Chem. 281, 36241-36248.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 36241-36248
-
-
Hanes, J.W.1
Thai, D.M.2
Johnson, K.A.3
-
39
-
-
33947170923
-
Single-turnover Kinetic Analysis of the Mutagenic Potential of 8-Oxo-7,8-dihydro-2′-deoxyguanosine during Gap-filling Synthesis Catalyzed by Human DNA Polymerases λ and β
-
Brown, J. A., Duym, W. W., Flower, J. D., and Zucai, S. (2007) Single-turnover Kinetic Analysis of the Mutagenic Potential of 8-Oxo-7,8-dihydro-2′-deoxyguanosine during Gap-filling Synthesis Catalyzed by Human DNA Polymerases λ and β. J. Mol. Biol. 367, 1258-1269.
-
(2007)
J. Mol. Biol
, vol.367
, pp. 1258-1269
-
-
Brown, J.A.1
Duym, W.W.2
Flower, J.D.3
Zucai, S.4
-
40
-
-
30944452765
-
Evidence the Errors Made by DNA Polymerase α are Corrected by DNA Polymerase δ
-
Pavlov, Y. I., Frahm, C., McElhinny, S. A. N., Niimi, A., Suzuki, M., and Kunkel, T. A. (2006) Evidence the Errors Made by DNA Polymerase α are Corrected by DNA Polymerase δ. Curr. Biol. 16, 202-207.
-
(2006)
Curr. Biol
, vol.16
, pp. 202-207
-
-
Pavlov, Y.I.1
Frahm, C.2
McElhinny, S.A.N.3
Niimi, A.4
Suzuki, M.5
Kunkel, T.A.6
|