Replication of damaged DNA: Molecular defect in Xeroderma pigmentosum variant cells

Mutation Research - DNA Repair

Volumn 435, Issue 2, 1999, Pages 111-119

  Cordonnier, Agnes M ^a   Fuchs, Robert P P ^a  

^a Cancerogenese Mutagenese Molec S   (France)

Author keywords

DNA; Replication; Xeroderma pigmentosum

Indexed keywords

DNA POLYMERASE; PYRIMIDINE DIMER;

DNA DAMAGE; DNA REPLICATION; DNA SYNTHESIS; EXCISION REPAIR; HUMAN; MAMMAL CELL; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; ULTRAVIOLET RADIATION; XERODERMA PIGMENTOSUM;

EID: 0032703301     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(99)00047-6     Document Type: Article

References (66)

1. Lehmann A.R. The relationship between pyrimidine dimers and replicating DNA in UV-irradiated human fibroblasts. Nucleic Acids Res. 7:1979;1901-1912.
2. Park S.D., Cleaver J.E. Postreplication repair: question of its definition and possible alteration in Xeroderma pigmentosum cell strains. Proc. Natl. Acad. Sci. U.S.A. 76:1979;3927-3931.
3. Cordeiro S.M., Zaritskaya L.S., Price L.K., Kaufmann W.K. Replication fork bypass of a pyrimidine dimer blocking leading strand DNA synthesis. J. Biol. Chem. 272:1997;13945-13954.
4. Svoboda D.L., Briley L.P., Vos J.M. Defective bypass replication of a leading strand cyclobutane thymine dimer in Xeroderma pigmentosum variant cell extracts. Cancer Res. 58:1998;2445-2448.
5. Ensch-Simon I., Burgers P.M., Taylor J.S. Bypass of a site-specific cis-syn thymine dimer in an SV40 vector during in vitro replication by HeLa and XPV cell-free extracts. Biochemistry. 37:1998;8218-8226.
6. Cordonnier A., Lehmann A.R., Fuchs R.P.P. Impaired translesion synthesis in Xeroderma pigmentosum variant extracts. Mol. Cell. Biol. 19:1999;2206-2211.
7. Masutani C., Araki M., Yamada A., Kusumoto R., Nogimori T., Maekawa T., Iwai S., Hanaoka F. Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity. EMBO J. 18:1999;3491-3501.
8. Waga S., Hannon G.J., Beach D., Stillman B. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature. 369:1994;574-578.
9. Carty M.P., Zernik K.M., McGrath S., Dixon K. UV light-induced DNA synthesis arrest in HeLa cells is associated with changes in phosphorylation of human single-stranded DNA-binding protein. EMBO J. 13:1994;2114-2123.
10. Lehmann A.R. Postreplication repair of DNA in ultraviolet-irradiated mammalian cells. J. Mol. Biol. 66:1972;319-337.
11. Ganesan A.K. Persistence of pyrimidine dimers during post-replication repair in ultraviolet light-irradiated Escherichia coli K12. J. Mol. Biol. 87:1974;103-119.
12. Resnick M.A., Boyce J., Cox B. Postreplication repair in Saccharomyces cerevisiae. J. Bacteriol. 146:1981;285-290.
13. Fornace A.J. Recombination of parent and daughter strand after uv-irradiation in mammalian cells. Nature (London). 304:1983;552-554.
14. Spivak G., Hanawalt P.C. Translesion DNA synthesis in the dihydrofolate reductase domain of UV-irradiated CHO cells. Biochemistry. 31:1992;6794-6800.
15. Meneghini R., Hanawalt P.C. T4-endonuclease V-sensitive sites in DNA from ultraviolet-irradiated human cells. Biochem. Biophys. Acta. 425:1976;428-437.
16. N.P. Higgins, K. Kato, B. Strauss, A model for replication repair in mammalian cells, J. Mol. Biol. (1976) 417-425.
17. Lehmann A.R., Kirk-Bell S., Arlett C.F., Paterson M.C., Lohman P.H.M., de Weerd-Kastelein E.A., Bootsma D. Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation. Proc. Natl. Acad. Sci. U.S.A. 72:1975;219-233.
18. Arlett C.F., Harcourt S.A., Broughton B.C. The influence of caffeine on cell survival in excision-proficient and excision-deficient xeroderma pigmentosum and normal human cell strains following ultraviolet-light irradiation. Mutat. Res. 33:1975;341-346.
19. Maher V.M., Ouellette L.M., Mittlestat M., McCormick J.J. Synergistic effect of caffeine on the cytotoxicity of ultraviolet irradiation and of hydrocarbon epoxides in strains of Xeroderma pigmentosum. Nature. 258:1975;760-763.
20. d'Ambrosio S.M., Setlow R.B. Defective and enhanced postreplication repair in classical and variant xeroderma pigmentosum cells treated with N-Acetoxy-2-acetylaminofluorene. Cancer Res. 38:1978;1147-1153.
21. Misra R.R., Vos J.-M.H. Defective replication of psoralen adducts detected at the gene-specific level in Xeroderma pigmentosum variant cells. Mol. Cell. Biol. 13:1993;1002-1012.
22. Maher V.M., Ouellette L.M., Curren R.D., McCormick J.J. Frequency of ultraviolet light-induced mutations is higher in Xeroderma pigmentosum variant cells than in normal human cells. Nature (London). 261:1976;593-595.
23. Cordeiro S.M., Boyer J.C., Smith B.A., Kaufmann W.K. Xeroderma pigmentosum variant and normal fibroblasts show the same response to the inhibition of DNA replication by benzo[a]pyrene-diol-epoxide-I. Carcinogenesis. 7:1986;1783-1786.
24. Boyer J.C., Kaufmann W.K., Brylawski B.P., Cordeiro-Stone M. Defective postreplication repair in Xeroderma pigmentosum variant fibroblasts. Cancer Res. 50:1990;2593-2598.
25. Berger C.A., Edenberg H.J. Pyrimidine dimers block simian virus 40 replication forks. Mol. Cell. Biol. 6:1986;3443-3450.
26. Sarasin A.R., Hanawalt P.C. Replication of ultraviolet-irradiated simian virus 40 in monkey kidney cells. J. Mol. Biol. 138:1980;299-319.
27. Stacks P.C., White J.H., Dixon K. Accommodation of pyrimidine dimers during replication of UV-damaged simian virus 40 DNA. Mol. Cell. Biol. 3:1983;1403-1411.
28. Bredberg A., Kraemer K.H., Seidman M.M. Restricted ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum cells. Proc. Natl. Acad. Sci. U.S.A. 83:1986;8273-8277.
29. Hauser J., Seidman M.M., Sidur K., Dixon K. Sequence specificity of point mutations induced during passage of a UV-irradiated shuttle vector plasmid in monkey cells. Mol. Cell. Biol. 6:1986;277-285.
30. Carty M.P., Hauser J., Levine A.S., Dixon K. Replication and mutagenesis of uv-damaged DNA templates in human and monkey cell extracts. Mol. Cell. Biol. 13:1993;533-542.
31. Thomas D.C., Nguyen D.C., Piegorsch W.W., Kunkel T.A. Relative probability of mutagenic translesion synthesis on the leading and lagging strands during replication of UV-irradiated DNA in a human cell extract. Biochemistry. 32:1993;11476-11482.
32. Thomas D.C., Svoboda D.L., Vos J.M., Kunkel T.A. Strand specificity of mutagenic bypass replication of DNA containing psoralen monoadducts in a human cell extract. Mol. Cell. Biol. 16:1996;2537-2544.
33. Carty M.P., Lawrence C.W., Dixon K. Complete replication of plasmid DNA containing a single UV-induced lesion in human cell extracts. J. Biol. Chem. 271:1996;9637-9647.
34. Svoboda D.L., Vos J.-M.H. Differential replication of a single, UV-induced lesion in the leading or lagging strand by a human cell extract: fork uncoupling or gap formation. Proc. Natl. Acad. Sci. U.S.A. 92:1995;11975-11979.
35. Thomas D.C., Veaute X., Kunkel T.A., Fuchs R.P.P. Mutagenic replication in human cell extracts of DNA containing site-specific N-2-acetylaminofluorene adducts. Proc. Natl. Acad. Sci. U.S.A. 91:1994;7752-7756.
36. Thomas D.C., Veaute X., Fuchs R.P.P., Kunkel T.A. Frequency and fidelity of translesion synthesis of site-specific N-2-acetylaminofluorene adducts during DNA replication in a human cell extract. J. Biol. Chem. 270:1995;21226-21233.
37. Veaute X., Sarasin A. Differential replication of a single N-2-acetylaminofluorene lesion in the leading or lagging strand DNA in a human cell extract. J. Biol. Chem. 272:1997;15351-15357.
38. Cordeiro S.M., Makhov A.M., Zaritskaya L.S., Griffith J.D. Analysis of DNA replication forks encountering a pyrimidine dimer in the template to the leading strand. J. Mol. Biol. 289:1999;1207-1218.
39. Masutani C., Kusumoto R., Yamada A., Dohmae N., Yokoi M., Yuasa M., Araki M., Iwai S., Takio M., Hanaoka F. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η Nature. 399:1999;700-704.
40. Johnson R.E., Kondratick C.M., Prakash S., Prakash L. hRAD30 mutations in the variant form of xeroderma pigmentosum. Science. 285:1999;263-265.
41. Myhr B.C., Turnbull D., Di P.J. Ultraviolet mutagenesis of normal and xeroderma pigmentosum variant human fibroblasts. Mutat. Res. 62:1979;341-353.
42. McCormick J.J., Kateley K.S., Watanabe M., Maher V.M. Abnormal sensitivity of human fibroblasts from xeroderma pigmentosum variants to transformation to anchorage independence by ultraviolet radiation. Cancer Res. 46:1986;489-492.
43. Wang Y.C., Maher V.M., McCormick J.J. Xeroderma pigmentosum variant cells are less likely than normal cells to incorporate dAMP opposite photoproducts during replication of UV-irradiated plasmids. Proc. Natl. Acad. Sci. U.S.A. 88:1991;7810-7814.
44. McGregor D., Wei V.M., Maher J.J., McCormick Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light. Mol. Cell. Biol. 19:1999;147-154.
45. Wang Y.C., Maher V.M., Mitchell D.L., McCormick J.J. Evidence from mutation spectra that the UV hypermutability of xeroderma pigmentosum variant cells reflects abnormal, error-prone replication on a template containing photoproducts. Mol. Cell. Biol. 13:1993;4276-4283.
46. Sykes R.C., Lin D., Hwang S.J., Framson P.E., Chinault A.C. Yeast ARS function and nuclear matrix association coincide in a short sequence from the human HPRT locus. Mol. Gen. Genet. 212:1988;301-309.
47. Rajagopalan M., Chi L., Woodgate R., O'Donnel M., Goodman M.F., Echols H. Activity of the purified mutagenesis proteins UmuC, UmuD′ and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III. Proc. Natl. Acad. Sci. U.S.A. 89:1992;10777-10781.
48. Napolitano R.L., Lambert I.B., Fuchs R.P.P. SOS factors involved in translesion synthesis. Proc. Natl. Acad. Sci. U.S.A. 94:1997;5733-5738.
49. Maenhaut-Michel G., Janel-Bintz R., Fuchs R.P.P. An umuDC-independent SOS pathway for frameshift mutagenesis. Mol. Gen. Genet. 235:1992;373-380.
50. Fuchs R.P.P., Napolitano R. Inactivation of DNA proofreading obviates the need for SOS induction in frameshift mutagenesis. Proc. Natl. Acad. Sci. U.S.A. 95:1998;13114-13119.
51. Wagner J., Gruz P., Kim S.-R., Yamada M., Matsui K., Fuchs R.P.P., Nohmi T. The dinB gene encodes a novel E. coli DNA polymerase (DNA pol IV) involved in mutagenesis. Mol. Cell. 4:1999;281-286.
52. Kim S.R., Maenhaut M.G., Yamada M., Yamamoto Y., Matsui K., Sofuni T., Nohmi T., Ohmori H. Multiple pathways for SOS-induced mutagenesis in Escherichia coli: an overexpression of dinB/dinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNA. Proc. Natl. Acad. Sci. U.S.A. 94:1997;13792-13797.
53. Lawrence C.W., Hinkle D.C. DNA polymerase ζ and the control of DNA damage induced mutagenesis in eukaryotes. Cancer Surveys. 28:1997;21-31.
54. Baynton K., Bresson A., Fuchs R.P.P. Distinct roles for Rev1p and Rev7p during translesion synthesis in Saccharomyces cerevisiae. Molec. Microbiol. 34:1999;. in press.
55. Nelson J.R., Lawrence C.W., Hinkle D.C. Deoxycytidyl transferase activity of yeast REV1 protein. Nature. 382:1996;729-731.
56. Johnson R.E., Prakash S., Prakash L. Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Polη Science. 283:1999;1001-1004.
57. McDonald J.P., Levine A.S., Woodgate R. The Saccharomyces cerevisiae RAD30 gene, a homologue of Escherichia coli dinB and umuC, is DNA damage inducible and functions in a novel error-free postreplication repair mechanism. Genetics. 147:1997;1557-1568.
58. Roush A.A., Suarez M., Friedberg E.C., Radman M., Siede W. Deletion of the Saccharomyces cerevisiae gene RAD30 encoding an Escherichia coli DinB homolog confers UV radiation sensitivity and altered mutability. Mol. Gen. Genet. 257:1998;686-692.
59. Johnson R.E., Prakash S., Prakash L. Yeast DNA repair protein RAD5 that promotes instability of simple repetitive sequences is a DNA-dependent ATPase. J. Biol. Chem. 269:1994;28259-28262.
60. Johnson R.E., Prakash S., Prakash L. Requirement of DNA polymerase activity of yeast rad30 protein for its biological function. J. Biol. Chem. 274:1999;15975-15977.
61. Gibbs P.E., McGregor W.G., Maher V.M., Nisson P., Lawrence C.W. A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta. Proc. Natl. Acad. Sci. U.S.A. 95:1998;6876-6880.
62. Friedberg E.C., Gerlach V.L. Novel DNA polymerase offer clues to the molecular basis of mutagenesis. Cell. 98:1999;413-416.
63. J.P. McDonald, V. Rapic-Otrin, J.A. Epstein, X. Wang, D.J. Wolgemuth, R. Woodgate, Genomics (1999) in press.
64. Wixler V., Laplantine E., Geerts D., Sonnenberg A., Petersohn D., Eckes B., Paulsson M., Aumailley M. Identification of novel interaction partners for the conserved membrane proximal region of α-integin cytoplasmic domains. FEBS Letters. 445:1999;351-355.
65. Jonczyk P., Nowicka A. Specific in vivo protein-protein interactions between Escherichia coli SOS mutagenesis proteins. J. Bacteriol. 178:1996;2580-2585.
66. Baynton K., Bresson-Roy A., Fuchs R.P.P. Analysis of damage tolerance pathways in Saccharomyces cerevisiae: a requirement for Rev3 DNA polymerase in translesion synthesis. Mol. Cell. Biol. 18:1998;960-966.