Fidelity of nucleotide insertion at 8-oxo-7,8-dihydroguanine by mammalian DNA polymerase δ : Steady-state and pre-steady-state kinetic analysis

Journal of Biological Chemistry

Volumn 276, Issue 6, 2001, Pages 3764-3771

  Einolf, Heidi J ^a   Guengerich, F Peter ^b  

^a NOVARTIS PHARMA AG   (Switzerland)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; CELLS; CHEMICAL BONDS; DNA; REACTION KINETICS;

NUCLEOTIDES;

ENZYMES;

8 HYDROXYGUANINE; CYCLINE; DEOXYADENOSINE TRIPHOSPHATE; DEOXYCYTIDINE TRIPHOSPHATE; DNA DIRECTED DNA POLYMERASE DELTA; 8-HYDROXYGUANINE; ADENOSINE TRIPHOSPHATE; CYTIDINE TRIPHOSPHATE; DNA DIRECTED DNA POLYMERASE GAMMA; DRUG DERIVATIVE; GUANINE; PRIMER DNA; RECOMBINANT PROTEIN;

AMINO ACID ANALYSIS; ARTICLE; BINDING AFFINITY; DISSOCIATION; DNA REPLICATION; ENZYME CONFORMATION; MOLECULAR MECHANICS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; STEADY STATE; ANIMAL; CATTLE; GENETICS; HUMAN; KINETICS; METABOLISM; NUCLEOTIDE SEQUENCE;

INSERTION SEQUENCES; MAMMALIA;

ADENOSINE TRIPHOSPHATE; ANIMALS; BASE SEQUENCE; CATTLE; CYTIDINE TRIPHOSPHATE; DNA POLYMERASE III; DNA PRIMERS; GUANINE; HUMANS; KINETICS; PROLIFERATING CELL NUCLEAR ANTIGEN; RECOMBINANT PROTEINS;

EID: 0035830851     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M006696200     Document Type: Article

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