Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase

Journal of Biological Chemistry

Volumn 284, Issue 10, 2009, Pages 6379-6388

  Sherrer, Shanen M ^a   Brown, Jessica A ^a   Pack, Lindsey R ^a   Jasti, Vijay P ^c   Fowler, Jason D ^a   Basu, Ashis K ^c   Suo, Zucai ^a,b,d  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF CONNECTICUT   (United States)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE RESIDUES; AMINOPYRENE; BINDING AFFINITIES; BIPHASIC; DIESEL EMISSION; DNA POLYMERASE; GENETIC MUTATIONS; IN-VIVO; KINETIC MECHANISM; KINETIC STUDY; LESION BYPASS; MECHANISTIC STUDIES; NITROPOLYCYCLIC AROMATIC HYDROCARBONS; PRE-STEADY-STATE KINETIC METHODS; SLOW PHASE; SULFOLOBUS SOLFATARICUS;

AROMATIC HYDROCARBONS; BINDING ENERGY; BINDING SITES; DNA; GENES; NUCLEOTIDES; POLYCYCLIC AROMATIC HYDROCARBONS; POLYMERS; YTTRIUM ALLOYS;

NUCLEIC ACIDS;

BACTERIAL DNA; DNA POLYMERASE; DNA POLYMERASE 4; NUCLEOTIDE; UNCLASSIFIED DRUG; 1 NITROPYRENE; 1-NITROPYRENE; ARCHAEAL DNA; ARCHAEAL PROTEIN; DNA DIRECTED DNA POLYMERASE; PYRENE DERIVATIVE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; CONTROLLED STUDY; DNA ADDUCT; DNA BINDING; DNA DAMAGE; DNA SEQUENCE; DNA STRUCTURE; DNA TEMPLATE; ENZYME ACTIVE SITE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; STEADY STATE; SULFOLOBUS SOLFATARICUS; CHEMISTRY; ENZYMOLOGY; EXHAUST GAS; GENETICS; KINETICS; METABOLISM; MUTATION; PHYSIOLOGY;

SULFOLOBUS SOLFATARICUS;

ARCHAEAL PROTEINS; CATALYSIS; DNA ADDUCTS; DNA DAMAGE; DNA, ARCHAEAL; DNA-DIRECTED DNA POLYMERASE; KINETICS; MUTATION; PYRENES; SULFOLOBUS SOLFATARICUS; VEHICLE EMISSIONS;

EID: 65249138294     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M808161200     Document Type: Article

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