Polymerization fidelity of a replicative DNA polymerase from the hyperthermophilic archaeon Sulfolobus solfataricus P2

Biochemistry

Volumn 48, Issue 31, 2009, Pages 7492-7501

  Zhang, Likui ^a,c   Brown, Jessica A ^a   Newmister, Sean A ^a   Suo, Zucai ^a,b,d  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c INSTITUTE OF MICROBIOLOGY   (China)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; BASE PAIRS; BUFFER PH; CONSERVED RESIDUES; DNA POLYMERASE; EXONUCLEASE; EXONUCLEASE ACTIVITY; GENOMIC DNA; GROUND-STATE; HIGH FIDELITY; HYPERTHERMOPHILIC ARCHAEON; IN-VIVO; INCORPORATION RATES; NUCLEOTIDE BINDING; PH CHANGE; POLYMERASE ACTIVITIES; PRE-STEADY-STATE KINETIC METHODS; REACTION TEMPERATURE; SULFOLOBUS SOLFATARICUS;

BINDING ENERGY; DNA; GENES; NUCLEIC ACIDS; NUCLEOTIDES;

POLYMERS;

DNA POLYMERASE; DNA POLYMERASE B1; MAGNESIUM ION; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; DNA REPLICATION; DNA SEQUENCE; ENZYME MECHANISM; ENZYME SPECIFICITY; MISMATCH REPAIR; NONHUMAN; PH; POLYMERIZATION; PRIORITY JOURNAL; SULFOLOBUS SOLFATARICUS; TEMPERATURE DEPENDENCE;

ARCHAEAL PROTEINS; CATALYTIC DOMAIN; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; EXONUCLEASES; KINETICS; MUTAGENESIS, SITE-DIRECTED; POLYMERS; SULFOLOBUS SOLFATARICUS;

ARCHAEA; CRENARCHAEOTA; SULFOLOBUS SOLFATARICUS;

EID: 68249097023     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi900532w     Document Type: Article

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