A lysine residue in the fingers subdomain of T7 DNA polymerase modulates the miscoding potential of 8-Oxo-7,8-dihydroguanosine

Structure

Volumn 13, Issue 11, 2005, Pages 1653-1659

  Brieba, Luis G ^a   Kokoska, Robert J ^b,c   Bebenek, Katarzyna ^b   Kunkel, Thomas A ^b   Ellenberger, Tom ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c U States Army Research Laboratory   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 OXO 7,8 DIHYDROGUANOSINE; DNA POLYMERASE; GUANOSINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONFORMATION; CRYSTAL STRUCTURE; KINETICS; PRIORITY JOURNAL; PROTEIN DOMAIN; STATISTICAL SIGNIFICANCE; WILD TYPE;

BACTERIOPHAGE T7; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DEOXYADENINE NUCLEOTIDES; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; GUANOSINE; LYSINE; MUTATION; PROTEIN STRUCTURE, TERTIARY;

EID: 27644597370     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2005.07.020     Document Type: Article

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