-
1
-
-
79951967895
-
The diagnostic challenge of psychiatric symptoms in neurodegenerative disease: Rates of and risk factors for prior psychiatric diagnosis in patients with early neurodegenerative disease
-
Woolley J. D., Khan B. K., Murthy N. K., Miller B. L., Rankin K. P., The diagnostic challenge of psychiatric symptoms in neurodegenerative disease: rates of and risk factors for prior psychiatric diagnosis in patients with early neurodegenerative disease Journal of Clinical Psychiatry 2011 72 2 126 133
-
(2011)
Journal of Clinical Psychiatry
, vol.72
, Issue.2
, pp. 126-133
-
-
Woolley, J.D.1
Khan, B.K.2
Murthy, N.K.3
Miller, B.L.4
Rankin, K.P.5
-
2
-
-
77955857970
-
Clinical features and pathogenesis of Alzheimer's disease: Involvement of mitochondria and mitochondrial DNA
-
Mancuso M., Orsucci D., LoGerfo A., Calsolaro V., Siciliano G., Clinical features and pathogenesis of Alzheimer's disease: involvement of mitochondria and mitochondrial DNA Advances in Experimental Medicine and Biology 2010 685 34 44
-
(2010)
Advances in Experimental Medicine and Biology
, vol.685
, pp. 34-44
-
-
Mancuso, M.1
Orsucci, D.2
Logerfo, A.3
Calsolaro, V.4
Siciliano, G.5
-
3
-
-
79955727727
-
The cholinergic system in aging and neuronal degeneration
-
Schliebs R., Arendt T., The cholinergic system in aging and neuronal degeneration Behavioural Brain Research 2011 221 2 555 563
-
(2011)
Behavioural Brain Research
, vol.221
, Issue.2
, pp. 555-563
-
-
Schliebs, R.1
Arendt, T.2
-
4
-
-
33846583006
-
Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease
-
DOI 10.1016/j.neurobiolaging.2006.02.007, PII S0197458006000455
-
Grudzien A., Shaw P., Weintraub S., Bigio E., Mash D. C., Mesulam M. M., Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease Neurobiology of Aging 2007 28 3 327 335 (Pubitemid 46178530)
-
(2007)
Neurobiology of Aging
, vol.28
, Issue.3
, pp. 327-335
-
-
Grudzien, A.1
Shaw, P.2
Weintraub, S.3
Bigio, E.4
Mash, D.C.5
Mesulam, M.M.6
-
5
-
-
33751270153
-
Locus ceruleus degeneration is ubiquitous in Alzheimer's disease: Possible implications for diagnosis and treatment
-
DOI 10.1111/j.1440-1789.2006.00725.x
-
Haglund M., Sjbeck M., Englund E., Locus ceruleus degeneration is ubiquitous in Alzheimer's disease: possible implications for diagnosis and treatment Neuropathology 2006 26 6 528 532 (Pubitemid 44800288)
-
(2006)
Neuropathology
, vol.26
, Issue.6
, pp. 528-532
-
-
Haglund, M.1
Sjobeck, M.2
Englund, E.3
-
6
-
-
67349158815
-
Variations in the neuropathology of familial Alzheimer's disease
-
Shepherd C., McCann H., Halliday G. M., Variations in the neuropathology of familial Alzheimer's disease Acta Neuropathologica 2009 118 1 37 52
-
(2009)
Acta Neuropathologica
, vol.118
, Issue.1
, pp. 37-52
-
-
Shepherd, C.1
McCann, H.2
Halliday, G.M.3
-
7
-
-
77956293354
-
Alzheimer's disease amyloid- links lens and brain pathology in down syndrome
-
Moncaster J. A., Pineda R., Moir R. D., Lu S., Burton M. A., Ghosh J. G., Ericsson M., Soscia S. J., Mocofanescu A., Folkerth R. D., Robb R. M., Kuszak J. R., Clark J. I., Tanzi R. E., Hunter D. G., Goldstein L. E., Alzheimer's disease amyloid- links lens and brain pathology in down syndrome PLoS ONE 2010 5 5
-
(2010)
PLoS ONE
, vol.5
, Issue.5
-
-
Moncaster, J.A.1
Pineda, R.2
Moir, R.D.3
Lu, S.4
Burton, M.A.5
Ghosh, J.G.6
Ericsson, M.7
Soscia, S.J.8
Mocofanescu, A.9
Folkerth, R.D.10
Robb, R.M.11
Kuszak, J.R.12
Clark, J.I.13
Tanzi, R.E.14
Hunter, D.G.15
Goldstein, L.E.16
-
8
-
-
77952316871
-
Cognitive deficits and associated neurological complications in individuals with Down's syndrome
-
Lott I. T., Dierssen M., Cognitive deficits and associated neurological complications in individuals with Down's syndrome The Lancet Neurology 2010 9 6 623 633
-
(2010)
The Lancet Neurology
, vol.9
, Issue.6
, pp. 623-633
-
-
Lott, I.T.1
Dierssen, M.2
-
9
-
-
13344293701
-
Presence of soluble amyloid -peptide precedes amyloid plaque formation in Down's syndrome
-
Teller J. K., Russo C., DeBusk L. M., Angelini G., Zaccheo D., Dagna-Bricarelli F., Scartezzini P., Bertolini S., Mann D. M. A., Tabaton M., Gambetti P., Presence of soluble amyloid -peptide precedes amyloid plaque formation in Down's syndrome Nature Medicine 1996 2 1 93 95
-
(1996)
Nature Medicine
, vol.2
, Issue.1
, pp. 93-95
-
-
Teller, J.K.1
Russo, C.2
Debusk, L.M.3
Angelini, G.4
Zaccheo, D.5
Dagna-Bricarelli, F.6
Scartezzini, P.7
Bertolini, S.8
Mann, D.M.A.9
Tabaton, M.10
Gambetti, P.11
-
10
-
-
79958729432
-
Positron emission tomography of brain -amyloid and tau levels in adults with down syndrome
-
Nelson L. D., Siddarth P., Kepe V., Scheibel K. E., Huang S. C., Barrio J. R., Small G. W., Positron emission tomography of brain -amyloid and tau levels in adults with down syndrome Archives of Neurology 2011 68 6 768 774
-
(2011)
Archives of Neurology
, vol.68
, Issue.6
, pp. 768-774
-
-
Nelson, L.D.1
Siddarth, P.2
Kepe, V.3
Scheibel, K.E.4
Huang, S.C.5
Barrio, J.R.6
Small, G.W.7
-
11
-
-
79451471618
-
The pathological process underlying Alzheimer's disease in individuals under thirty
-
Braak H., Del Tredici K., The pathological process underlying Alzheimer's disease in individuals under thirty Acta Neuropathologica 2011 121 2 171 181
-
(2011)
Acta Neuropathologica
, vol.121
, Issue.2
, pp. 171-181
-
-
Braak, H.1
Del Tredici, K.2
-
12
-
-
34848922135
-
APP locus duplication in a Finnish family with dementia and intracerebral haemorrhage
-
Rovelet-Lecrux A., Frebourg T., Tuominen H., Majamaa K., Campion D., Remes A. M., APP locus duplication in a Finnish family with dementia and intracerebral haemorrhage Journal of Neurology, Neurosurgery and Psychiatry 2007 78 10 1158 1159
-
(2007)
Journal of Neurology, Neurosurgery and Psychiatry
, vol.78
, Issue.10
, pp. 1158-1159
-
-
Rovelet-Lecrux, A.1
Frebourg, T.2
Tuominen, H.3
Majamaa, K.4
Campion, D.5
Remes, A.M.6
-
14
-
-
33846983823
-
How and when environmental agents and dietary factors affect the course of Alzheimer's disease: The "LEARn" model (Latent Early-Life Associated Regulation) may explain the triggering of AD
-
DOI 10.2174/156720507780362164
-
Lahiri D. K., Maloney B., Basha M. R., Yuan W. G., Zawia N. H., How and when environmental agents and dietary factors affect the course of Alzheimer's disease: the LEARn model (Latent Early-Life Associated Regulation) may explain the triggering of AD Current Alzheimer Research 2007 4 2 219 228 (Pubitemid 46557511)
-
(2007)
Current Alzheimer Research
, vol.4
, Issue.2
, pp. 219-228
-
-
Lahiri, D.K.1
Maloney, B.2
Basha, Md.R.3
Yuan, W.G.4
Zawia, N.H.5
-
17
-
-
57149120604
-
Setting a public health research agenda for Down syndrome: Summary of a meeting sponsored by the centers for disease control and prevention and the national down syndrome society
-
DOI 10.1002/ajmg.a.32581
-
Rasmussen S. A., Whitehead N., Collier S. A., Fras J. L., Setting a public health research agenda for Down syndrome: summary of a meeting sponsored by the centers for disease control and prevention and the national down syndrome society American Journal of Medical Genetics, Part A 2008 146 23 2998 3010 (Pubitemid 352774639)
-
(2008)
American Journal of Medical Genetics, Part A
, vol.146
, Issue.23
, pp. 2998-3010
-
-
Rasmussen, S.A.1
Whitehead, N.2
Collier, S.A.3
Frias, J.L.4
-
18
-
-
77952020384
-
The role of chromosome 21 in hematology and oncology
-
Fonatsch C., The role of chromosome 21 in hematology and oncology Genes Chromosomes and Cancer 2010 49 6 497 508
-
(2010)
Genes Chromosomes and Cancer
, vol.49
, Issue.6
, pp. 497-508
-
-
Fonatsch, C.1
-
19
-
-
33947168891
-
Mechanisms of disease: DNA repair defects and neurological disease
-
DOI 10.1038/ncpneuro0448, PII NCPNEURO0448
-
Rao K. S., Mechanisms of disease: DNA repair defects and neurological disease Nature Clinical Practice Neurology 2007 3 3 162 172 (Pubitemid 46403943)
-
(2007)
Nature Clinical Practice Neurology
, vol.3
, Issue.3
, pp. 162-172
-
-
Rao, K.S.1
-
21
-
-
5044234361
-
Chromosome 21 and Down syndrome: From genomics to pathophysiology
-
DOI 10.1038/nrg1448
-
Antonarakis S. E., Lyle R., Dermitzakis E. T., Reymond A., Deutsch S., Chromosome 21 and Down syndrome: from genomics to pathophysiology Nature Reviews Genetics 2004 5 10 725 738 (Pubitemid 39336357)
-
(2004)
Nature Reviews Genetics
, vol.5
, Issue.10
, pp. 725-738
-
-
Antonarakis, S.E.1
Lyle, R.2
Dermitzakis, E.T.3
Reymond, A.4
Deutsch, S.5
-
22
-
-
79951897216
-
A noradrenergic lesion exacerbates neurodegeneration in a down syndrome mouse model
-
Lockrow J., Boger H., Gerhardt G., Aston-Jones G., Bachman D., Granholm A.-C., A noradrenergic lesion exacerbates neurodegeneration in a down syndrome mouse model Journal of Alzheimer's Disease 2011 23 3 471 489
-
(2011)
Journal of Alzheimer's Disease
, vol.23
, Issue.3
, pp. 471-489
-
-
Lockrow, J.1
Boger, H.2
Gerhardt, G.3
Aston-Jones, G.4
Bachman, D.5
Granholm, A.-C.6
-
23
-
-
0035671551
-
Dementia in people with Down's syndrome
-
DOI 10.1002/gps.502
-
Tyrrell J., Cosgrave M., McCarron M., McPherson J., Calvert J., Kelly A., McLaughlin M., Gill M., Lawlor B. A., Dementia in people with Down's syndrome International Journal of Geriatric Psychiatry 2001 16 12 1168 1174 (Pubitemid 34044185)
-
(2001)
International Journal of Geriatric Psychiatry
, vol.16
, Issue.12
, pp. 1168-1174
-
-
Tyrrell, J.1
Cosgrave, M.2
McCarron, M.3
McPherson, J.4
Calvert, J.5
Kelly, A.6
McLaughlin, M.7
Gill, M.8
Lawlor, B.A.9
-
24
-
-
77952318065
-
Executive function in adolescents with Down Syndrome
-
Lanfranchi S., Jerman O., Dal Pont E., Alberti A., Vianello R., Executive function in adolescents with Down Syndrome Journal of Intellectual Disability Research 2010 54 4 308 319
-
(2010)
Journal of Intellectual Disability Research
, vol.54
, Issue.4
, pp. 308-319
-
-
Lanfranchi, S.1
Jerman, O.2
Dal Pont, E.3
Alberti, A.4
Vianello, R.5
-
25
-
-
3042857513
-
Review of donepezil, rivastigmine, galantamine and memantine for the treatment of dementia in Alzheimer's disease in adults with Down syndrome: Implications for the intellectual disability population
-
DOI 10.1002/gps.1077
-
Prasher V. P., Review of donepezil, rivastigmine, galantamine and memantine for the treatment of dementia in Alzheimer's disease in adults with Down syndrome: implications for the intellectual disability population International Journal of Geriatric Psychiatry 2004 19 6 509 515 (Pubitemid 38877997)
-
(2004)
International Journal of Geriatric Psychiatry
, vol.19
, Issue.6
, pp. 509-515
-
-
Prasher, V.P.1
-
26
-
-
0034854122
-
Down syndrome and alzheimer's disease: A link between development and aging
-
DOI 10.1002/mrdd.1025
-
Lott I. T., Head E., Down syndrome and alzheimer's disease: a link between development and aging Mental Retardation and Developmental Disabilities Research Reviews 2001 7 3 172 178 (Pubitemid 32843808)
-
(2001)
Mental Retardation and Developmental Disabilities Research Reviews
, vol.7
, Issue.3
, pp. 172-178
-
-
Lott, I.T.1
Head, E.2
-
27
-
-
11444269588
-
Alzheimer disease and Down syndrome: Factors in pathogenesis
-
DOI 10.1016/j.neurobiolaging.2004.08.005, PII S0197458004002672, Developmental Origins of Aging in the Brain and Blood Vessels
-
Lott I. T., Head E., Alzheimer disease and Down syndrome: factors in pathogenesis Neurobiology of Aging 2005 26 3 383 389 (Pubitemid 40082722)
-
(2005)
Neurobiology of Aging
, vol.26
, Issue.3
, pp. 383-389
-
-
Lott, I.T.1
Head, E.2
-
28
-
-
48249095748
-
Down syndrome fibroblast model of Alzheimer-related endosome pathology: Accelerated endocytosis promotes late endocytic defects
-
Cataldo A. M., Mathews P. M., Boiteau A. B., Hassinger L. C., Peterhoff C. M., Jiang Y., Mullaney K., Neve R. L., Gruenberg J., Nixon R. A., Down syndrome fibroblast model of Alzheimer-related endosome pathology: accelerated endocytosis promotes late endocytic defects American Journal of Pathology 2008 173 2 370 384
-
(2008)
American Journal of Pathology
, vol.173
, Issue.2
, pp. 370-384
-
-
Cataldo, A.M.1
Mathews, P.M.2
Boiteau, A.B.3
Hassinger, L.C.4
Peterhoff, C.M.5
Jiang, Y.6
Mullaney, K.7
Neve, R.L.8
Gruenberg, J.9
Nixon, R.A.10
-
29
-
-
0033869715
-
Endocytic pathway abnormalities precede amyloid β deposition in sporadic alzheimer's disease and down syndrome: Differential effects of APOE genotype and presenilin mutations
-
Cataldo A. M., Peterhoff C. M., Troncoso J. C., Gomez-Isla T., Hyman B. T., Nixon R. A., Endocytic pathway abnormalities precede amyloid deposition in sporadic alzheimer's disease and down syndrome: differential effects of APOE genotype and presenilin mutations American Journal of Pathology 2000 157 1 277 286 (Pubitemid 30641743)
-
(2000)
American Journal of Pathology
, vol.157
, Issue.1
, pp. 277-286
-
-
Cataldo, A.M.1
Peterhoff, C.M.2
Troncoso, J.C.3
Gomez-Isla, T.4
Hyman, B.T.5
Nixon, R.A.6
-
30
-
-
36448964118
-
Gene expression profiling in the adult Down syndrome brain
-
DOI 10.1016/j.ygeno.2007.08.005, PII S0888754307002054
-
Lockstone H. E., Harris L. W., Swatton J. E., Wayland M. T., Holland A. J., Bahn S., Gene expression profiling in the adult Down syndrome brain Genomics 2007 90 6 647 660 (Pubitemid 350166832)
-
(2007)
Genomics
, vol.90
, Issue.6
, pp. 647-660
-
-
Lockstone, H.E.1
Harris, L.W.2
Swatton, J.E.3
Wayland, M.T.4
Holland, A.J.5
Bahn, S.6
-
31
-
-
0036406902
-
The brain in Down syndrome (Trisomy 21)
-
DOI 10.1007/s00415-002-0799-9
-
Lubec G., Engidawork E., The brain in Down syndrome (Trisomy 21) Journal of Neurology 2002 249 10 1347 1356 (Pubitemid 35217655)
-
(2002)
Journal of Neurology
, vol.249
, Issue.10
, pp. 1347-1356
-
-
Lubec, G.1
Engidawork, E.2
-
32
-
-
0037186074
-
Altered metabolism of the amyloid β precursor protein is associated with mitochondrial dysfunction in Down's syndrome
-
DOI 10.1016/S0896-6273(02)00604-9
-
Busciglio J., Pelsman A., Wong C., Pigino G., Yuan M., Mori H., Yankner B. A., Altered metabolism of the amyloid precursor protein is associated with mitochondrial dysfunction in Down's syndrome Neuron 2002 33 5 677 688 (Pubitemid 34219240)
-
(2002)
Neuron
, vol.33
, Issue.5
, pp. 677-688
-
-
Busciglio, J.1
Pelsman, A.2
Wong, C.3
Pigino, G.4
Yuan, M.5
Mori, H.6
Yankner, B.A.7
-
33
-
-
75149118999
-
Neuroinflammation in Alzheimer's disease and mild cognitive impairment: A field in its infancy
-
McGeer E. G., McGeer P. L., Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy Journal of Alzheimer's Disease 2010 19 1 355 361
-
(2010)
Journal of Alzheimer's Disease
, vol.19
, Issue.1
, pp. 355-361
-
-
McGeer, E.G.1
McGeer, P.L.2
-
34
-
-
77955281765
-
Activated astroglia during chronic inflammation in Alzheimer's disease-Do they neglect their neurosupportive roles?
-
Fuller S., Steele M., Mnch G., Activated astroglia during chronic inflammation in Alzheimer's disease-Do they neglect their neurosupportive roles? Mutation Research 2010 690 1-2 40 49
-
(2010)
Mutation Research
, vol.690
, Issue.12
, pp. 40-49
-
-
Fuller, S.1
Steele, M.2
Mnch, G.3
-
35
-
-
14644396515
-
Ets-2 promotes the activation of a mitochondrial death pathway in down's syndrome neurons
-
DOI 10.1523/JNEUROSCI.5107-04.2005
-
Helguera P., Pelsman A., Pigino G., Wolvetang E., Head E., Busciglio J., ets-2 promotes the activation of a mitochondrial death pathway in down's syndrome neurons Journal of Neuroscience 2005 25 9 2295 2303 (Pubitemid 40322270)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.9
, pp. 2295-2303
-
-
Helguera, P.1
Pelsman, A.2
Pigino, G.3
Wolvetang, E.4
Head, E.5
Busciglio, J.6
-
36
-
-
33748744258
-
Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome
-
DOI 10.1093/hmg/ddl211
-
Shukkur E. A., Shimohata A., Akagi T., Yu W., Yamaguchi M., Murayama M., Chui D., Takeuchi T., Amano K., Subramhanya K. H., Hashikawa T., Sago H., Epstein C. J., Takashima A., Yamakawa K., Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome Human Molecular Genetics 2006 15 18 2752 2762 (Pubitemid 44400402)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.18
, pp. 2752-2762
-
-
Shukkur, E.A.1
Shimohata, A.2
Akagi, T.3
Yu, W.4
Yamaguchi, M.5
Murayama, M.6
Chui, D.7
Takeuchi, T.8
Amano, K.9
Subramhanya, K.H.10
Hashikawa, T.11
Sago, H.12
Epstein, C.J.13
Takashima, A.14
Yamakawa, K.15
-
37
-
-
1642268979
-
Functional and morphological alterations in compound transgenic mice overexpreszing Cu/Zn superoxide dismutaze and amyloid precursor protein
-
DOI 10.1111/j.1460-9568.2004.03188.x
-
Harris-Cerruti C., Kamsler A., Kaplan B., Lamb B., Segal M., Groner Y., Functional and morphological alterations in compound transgenic mice overexpreszing Cu/Zn superoxide dismutaze and amyloid precursor protein European Journal of Neuroscience 2004 19 5 1174 1190 (Pubitemid 38387195)
-
(2004)
European Journal of Neuroscience
, vol.19
, Issue.5
, pp. 1174-1190
-
-
Harris-Cerruti, C.1
Kamsler, A.2
Kaplan, B.3
Lamb, B.4
Segal, M.5
Groner, Y.6
-
38
-
-
33846081524
-
Beta-amyloid, oxidative stress and down syndrome
-
DOI 10.2174/156720506779025305
-
Lott I. T., Head E., Doran E., Busciglio J., Beta-amyloid, oxidative stress and down syndrome Current Alzheimer Research 2006 3 5 521 528 (Pubitemid 46066428)
-
(2006)
Current Alzheimer Research
, vol.3
, Issue.5
, pp. 521-528
-
-
Lott, I.T.1
Head, E.2
Doran, E.3
Busciglio, J.4
-
40
-
-
0242348738
-
Mouse models of Down syndrome: How useful can they be? Comparison of the gene content of human chromosome 21 with orthologous mouse genomic regions
-
DOI 10.1016/S0378-1119(03)00769-8
-
Gardiner K., Fortna A., Bechtel L., Davisson M. T., Mouse models of Down syndrome: how useful can they be? Comparison of the gene content of human chromosome 21 with orthologous mouse genomic regions Gene 2003 318 1-2 137 147 (Pubitemid 37338399)
-
(2003)
Gene
, vol.318
, Issue.1-2
, pp. 137-147
-
-
Gardiner, K.1
Fortna, A.2
Bechtel, L.3
Davisson, M.T.4
-
41
-
-
69949189925
-
Age-dependent dysregulation of brain amyloid precursor protein in the Ts65Dn Down syndrome mouse model
-
Choi J. H. K., Berger J. D., Mazzella M. J., Morales-Corraliza J., Cataldo A. M., Nixon R. A., Ginsberg S. D., Levy E., Mathews P. M., Age-dependent dysregulation of brain amyloid precursor protein in the Ts65Dn Down syndrome mouse model Journal of Neurochemistry 2009 110 6 1818 1827
-
(2009)
Journal of Neurochemistry
, vol.110
, Issue.6
, pp. 1818-1827
-
-
Choi, J.H.K.1
Berger, J.D.2
Mazzella, M.J.3
Morales-Corraliza, J.4
Cataldo, A.M.5
Nixon, R.A.6
Ginsberg, S.D.7
Levy, E.8
Mathews, P.M.9
-
42
-
-
33745512851
-
Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration
-
DOI 10.1016/j.neuron.2006.05.022, PII S0896627306004144
-
Salehi A., Delcroix J. D., Belichenko P. V., Zhan K., Wu C., Valletta J. S., Takimoto-Kimura R., Kleschevnikov A. M., Sambamurti K., Chung P. P., Xia W., Villar A., Campbell W. A., Kulnane L. S., Nixon R. A., Lamb B. T., Epstein C. J., Stokin G. B., Goldstein L. S. B., Mobley W. C., Increased app expression in a mouse model of Down's Syndrome disrupts NGF transport and causes cholinergic neuron degeneration Neuron 2006 51 1 29 42 (Pubitemid 43963336)
-
(2006)
Neuron
, vol.51
, Issue.1
, pp. 29-42
-
-
Salehi, A.1
Delcroix, J.-D.2
Belichenko, P.V.3
Zhan, K.4
Wu, C.5
Valletta, J.S.6
Takimoto-Kimura, R.7
Kleschevnikov, A.M.8
Sambamurti, K.9
Chung, P.P.10
Xia, W.11
Villar, A.12
Campbell, W.A.13
Kulnane, L.S.14
Nixon, R.A.15
Lamb, B.T.16
Epstein, C.J.17
Stokin, G.B.18
Goldstein, L.S.B.19
Mobley, W.C.20
more..
-
43
-
-
3042521332
-
Behavioral and neurobiological markers of Alzheimer's disease in Ts65Dn mice: Effects of estrogen
-
DOI 10.1016/j.neurobiolaging.2003.10.010, PII S0197458003002409
-
Hunter C. L., Bimonte-Nelson H. A., Nelson M., Eckman C. B., Granholm A. C., Behavioral and neurobiological markers of Alzheimer's disease in Ts65Dn mice: effects of estrogen Neurobiology of Aging 2004 25 7 873 884 (Pubitemid 38813167)
-
(2004)
Neurobiology of Aging
, vol.25
, Issue.7
, pp. 873-884
-
-
Hunter, C.L.1
Bimonte-Nelson, H.A.2
Nelson, M.3
Eckman, C.B.4
Granholm, A.-C.5
-
44
-
-
79955755924
-
Neural stem cells reduce hippocampal tau and reelin accumulation in aged Ts65Dn down syndrome mice
-
Kern D. S., Maclean K. N., Jiang H., Synder E. Y., Sladek J. R., Bjugstad K. B., Neural stem cells reduce hippocampal tau and reelin accumulation in aged Ts65Dn down syndrome mice Cell Transplantation 2011 20 3 371 379
-
(2011)
Cell Transplantation
, vol.20
, Issue.3
, pp. 371-379
-
-
Kern, D.S.1
MacLean, K.N.2
Jiang, H.3
Synder, E.Y.4
Sladek, J.R.5
Bjugstad, K.B.6
-
45
-
-
71749117874
-
Amyloid overload does not directly correlate with SAPK/JNK activation and tau protein phosphorylation in the cerebellar cortex of Ts65Dn mice
-
Lomoio S., Scherini E., Necchi D., -Amyloid overload does not directly correlate with SAPK/JNK activation and tau protein phosphorylation in the cerebellar cortex of Ts65Dn mice Brain Research 2009 1297 198 206
-
(2009)
Brain Research
, vol.1297
, pp. 198-206
-
-
Lomoio, S.1
Scherini, E.2
Necchi, D.3
-
46
-
-
9144267928
-
Minocycline prevents cholinergic loss in a mouse model of Down's syndrome
-
DOI 10.1002/ana.20250
-
Hunter C. L., Bachman D., Granholm A. C., Minocycline prevents cholinergic loss in a mouse model of Down's syndrome Annals of Neurology 2004 56 5 675 688 (Pubitemid 39540748)
-
(2004)
Annals of Neurology
, vol.56
, Issue.5
, pp. 675-688
-
-
Hunter, C.L.1
Bachman, D.2
Granholm, A.-C.3
-
47
-
-
77949489547
-
Impaired plasticity at specific subset of striatal synapses in the Ts65Dn mouse model of down syndrome
-
Di Filippo M., Tozzi A., Ghiglieri V., Picconi B., Costa C., Cipriani S., Tantucci M., Belcastro V., Calabresi P., Impaired plasticity at specific subset of striatal synapses in the Ts65Dn mouse model of down syndrome Biological Psychiatry 2010 67 7 666 671
-
(2010)
Biological Psychiatry
, vol.67
, Issue.7
, pp. 666-671
-
-
Di Filippo, M.1
Tozzi, A.2
Ghiglieri, V.3
Picconi, B.4
Costa, C.5
Cipriani, S.6
Tantucci, M.7
Belcastro, V.8
Calabresi, P.9
-
48
-
-
59649101958
-
Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of down syndrome
-
Belichenko P. V., Kleschevnikov A. M., Masliah E., Wu C., Takimoto-Kimura R., Salehi A., Mobley W. C., Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of down syndrome Journal of Comparative Neurology 2009 512 4 453 466
-
(2009)
Journal of Comparative Neurology
, vol.512
, Issue.4
, pp. 453-466
-
-
Belichenko, P.V.1
Kleschevnikov, A.M.2
Masliah, E.3
Wu, C.4
Takimoto-Kimura, R.5
Salehi, A.6
Mobley, W.C.7
-
49
-
-
2942591228
-
Failed retrograde transport of NGF in a mouse model of Down's syndrome: Reversal of cholinergic neurodegenerative phenotypes following NGF infusion
-
DOI 10.1073/pnas.181219298
-
Cooper J. D., Salehi A., Delcroix J. D., Howe C. L., Belichenko P. V., Chua-Couzens J., Kilbridge J. F., Carlson E. J., Epstein C. J., Mobley W. C., Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion Proceedings of the National Academy of Sciences of the United States of America 2001 98 18 10439 10444 (Pubitemid 32803038)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.18
, pp. 10439-10444
-
-
Cooper, J.D.1
Salehi, A.2
Delcroix, J.-D.3
Howe, C.L.4
Belichenko, P.V.5
Chua-Couzens, J.6
Kilbridge, J.F.7
Carlson, E.J.8
Epstein, C.J.9
Mobley, W.C.10
-
50
-
-
0344405753
-
Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome
-
DOI 10.1016/S0168-0102(03)00005-1
-
Hunter C. L., Isacson O., Nelson M., Bimonte-Nelson H., Seo H., Lin L., Ford K., Kindy M. S., Granholm A. C., Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome Neuroscience Research 2003 45 4 437 445 (Pubitemid 36355843)
-
(2003)
Neuroscience Research
, vol.45
, Issue.4
, pp. 437-445
-
-
Hunter, C.L.1
Isacson, O.2
Nelson, M.3
Bimonte-Nelson, H.4
Seo, H.5
Lin, L.6
Ford, K.7
Kindy, M.S.8
Granholm, A.-C.9
-
51
-
-
18244388693
-
Abnormal APP, cholinergic and cognitive function in Ts65Dn Down's model mice
-
DOI 10.1016/j.expneurol.2004.11.017
-
Seo H., Isacson O., Abnormal APP, cholinergic and cognitive function in Ts65Dn Down's model mice Experimental Neurology 2005 193 2 469 480 (Pubitemid 40626769)
-
(2005)
Experimental Neurology
, vol.193
, Issue.2
, pp. 469-480
-
-
Seo, H.1
Isacson, O.2
-
52
-
-
0037450168
-
Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome
-
DOI 10.1016/S0166-4328(02)00082-7, PII S0166432802000827
-
Bimonte-Nelson H. A., Hunter C. L., Nelson M. E., Granholm A. C. E., Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome Behavioural Brain Research 2003 139 1-2 47 57 (Pubitemid 36300789)
-
(2003)
Behavioural Brain Research
, vol.139
, Issue.1-2
, pp. 47-57
-
-
Bimonte-Nelson, H.A.1
Hunter, C.L.2
Nelson, M.E.3
Granholm, A.-C.E.4
-
53
-
-
0034097607
-
Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of down's syndrome
-
DOI 10.1006/exnr.1999.7289
-
Granholm A. C. E., Sanders L. A., Crnic L. S., Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of down's syndrome Experimental Neurology 2000 161 2 647 663 (Pubitemid 30137022)
-
(2000)
Experimental Neurology
, vol.161
, Issue.2
, pp. 647-663
-
-
Granholm, A.-C.E.1
Sanders, L.A.2
Crnic, L.S.3
-
54
-
-
10544243361
-
Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome
-
DOI 10.1073/pnas.93.23.13333
-
Holtzman D. M., Santucci D., Kilbridge J., Chua-Couzens J., Fontana D. J., Daniels S. E., Johnson R. M., Chen K., Sun Y., Carlson E., Alleva E., Epstein C. J., Mobley W. C., Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome Proceedings of the National Academy of Sciences of the United States of America 1996 93 23 13333 13338 (Pubitemid 26382816)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.23
, pp. 13333-13338
-
-
Holtzman, D.M.1
Santucci, D.2
Kilbridge, J.3
Chua-Couzens, J.4
Fontana, D.J.5
Daniels, S.E.6
Johnson, R.M.7
Chen, K.8
Sun, Y.9
Carlson, E.10
Alleva, E.11
Epstein, C.J.12
Mobley, W.C.13
-
55
-
-
77951836101
-
Restoration of norepinephrine-modulated contextual memory in a mouse model of Down syndrome
-
Salehi A., Faizi M., Colas D., Valletta J., Laguna J., Takimoto-Kimura R., Kleschevnikov A., Wagner S. L., Aisen P., Shamloo M., Mobley W. C., Restoration of norepinephrine-modulated contextual memory in a mouse model of Down syndrome Science Translational Medicine 2009 1 7 7 17
-
(2009)
Science Translational Medicine
, vol.1
, Issue.7
, pp. 7-17
-
-
Salehi, A.1
Faizi, M.2
Colas, D.3
Valletta, J.4
Laguna, J.5
Takimoto-Kimura, R.6
Kleschevnikov, A.7
Wagner, S.L.8
Aisen, P.9
Shamloo, M.10
Mobley, W.C.11
-
56
-
-
0037460101
-
Behavioral comparison of 4 and 6 month-old Ts65Dn mice: Age-related impairments in working and reference memory
-
DOI 10.1016/S0166-4328(02)00275-9, PII S0166432802002759
-
Hunter C. L., Bimonte H. A., Granholm A. C. E., Behavioral comparison of 4 and 6 month-old Ts65Dn mice: age-related impairments in working and reference memory Behavioural Brain Research 2003 138 2 121 131 (Pubitemid 36071351)
-
(2003)
Behavioural Brain Research
, vol.138
, Issue.2
, pp. 121-131
-
-
Hunter, C.L.1
Bimonte, H.A.2
Granholm, A.-C.E.3
-
57
-
-
65949098892
-
The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome
-
Belichenko N. P., Belichenko P. V., Kleschevnikov A. M., Salehi A., Reeves R. H., Mobley W. C., The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome Journal of Neuroscience 2009 29 18 5938 5948
-
(2009)
Journal of Neuroscience
, vol.29
, Issue.18
, pp. 5938-5948
-
-
Belichenko, N.P.1
Belichenko, P.V.2
Kleschevnikov, A.M.3
Salehi, A.4
Reeves, R.H.5
Mobley, W.C.6
-
58
-
-
34447338354
-
Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice
-
DOI 10.1093/hmg/ddm022
-
Olson L. E., Roper R. J., Sengstaken C. L., Peterson E. A., Aquino V., Galdzicki Z., Siarey R., Pletnikov M., Moran T. H., Reeves R. H., Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice Human Molecular Genetics 2007 16 7 774 782 (Pubitemid 47061624)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.7
, pp. 774-782
-
-
Olson, L.E.1
Roper, R.J.2
Sengstaken, C.L.3
Peterson, E.A.4
Aquino, V.5
Galdzicki, Z.6
Siarey, R.7
Pletnikov, M.8
Moran, T.H.9
Reeves, R.H.10
-
59
-
-
0036468772
-
Alzheimer's disease and Down's syndrome: Roles of APP, trophic factors and ACh
-
DOI 10.1016/S0166-2236(02)02037-4, PII S0166223602020373
-
Isacson O., Seo H., Lin L., Albeck D., Granholm A. C., Alzheimer's disease and Down's syndrome: roles of APP, trophic factors and ACh Trends in Neurosciences 2002 25 2 79 84 (Pubitemid 34123299)
-
(2002)
Trends in Neurosciences
, vol.25
, Issue.2
, pp. 79-84
-
-
Isacson, O.1
Seo, H.2
Lin, L.3
Albeck, D.4
Granholm, A.-C.5
-
60
-
-
33748300905
-
Reduced short latency afferent inhibition in patients with Down syndrome and Alzheimer-type dementia
-
DOI 10.1016/j.clinph.2006.07.134, PII S1388245706011436
-
Nardone R., Marth R., Ausserer H., Bratti A., Tezzon F., Reduced short latency afferent inhibition in patients with Down syndrome and Alzheimer-type dementia Clinical Neurophysiology 2006 117 10 2204 2210 (Pubitemid 44333280)
-
(2006)
Clinical Neurophysiology
, vol.117
, Issue.10
, pp. 2204-2210
-
-
Nardone, R.1
Marth, R.2
Ausserer, H.3
Bratti, A.4
Tezzon, F.5
-
61
-
-
33947673494
-
Pharmacotherapy for cognitive impairment in a mouse model of Down syndrome
-
DOI 10.1038/nn1860, PII NN1860
-
Fernandez F., Morishita W., Zuniga E., Nguyen J., Blank M., Malenka R. C., Garner C. C., Pharmacotherapy for cognitive impairment in a mouse model of Down syndrome Nature Neuroscience 2007 10 4 411 413 (Pubitemid 46494581)
-
(2007)
Nature Neuroscience
, vol.10
, Issue.4
, pp. 411-413
-
-
Fernandez, F.1
Morishita, W.2
Zuniga, E.3
Nguyen, J.4
Blank, M.5
Malenka, R.C.6
Garner, C.C.7
-
62
-
-
0029114706
-
A mouse model for Down syndrome exhibits learning and behaviour deficits
-
Reeves R. H., Irving N. G., Moran T. H., Wohn A., Kitt C., Sisodia S. S., Schmidt C., Bronson R. T., Davisson M. T., A mouse model for Down syndrome exhibits learning and behaviour deficits Nature Genetics 1995 11 2 177 184
-
(1995)
Nature Genetics
, vol.11
, Issue.2
, pp. 177-184
-
-
Reeves, R.H.1
Irving, N.G.2
Moran, T.H.3
Wohn, A.4
Kitt, C.5
Sisodia, S.S.6
Schmidt, C.7
Bronson, R.T.8
Davisson, M.T.9
-
63
-
-
0031890117
-
Impaired spatial working and reference memory in segmental trisomy (Ts65Dn) mice
-
DOI 10.1016/S0166-4328(97)00116-2, PII S0166432897001162
-
Demas G. E., Nelson R. J., Krueger B. K., Yarowsky P. J., Impaired spatial working and reference memory in segmental trisomy (Ts65Dn) mice Behavioural Brain Research 1998 90 2 199 201 (Pubitemid 28080561)
-
(1998)
Behavioural Brain Research
, vol.90
, Issue.2
, pp. 199-201
-
-
Demas, G.E.1
Nelson, R.J.2
Krueger, B.K.3
Yarowsky, P.J.4
-
64
-
-
0035825304
-
Ts65Dn mice, a model for Down syndrome, have deficits in context discrimination learning suggesting impaired hippocampal function
-
DOI 10.1016/S0166-4328(00)00313-2, PII S0166432800003132
-
Hyde L. A., Frisone D. F., Crnic L. S., Ts65Dn mice, a model for Down syndrome, have deficits in context discrimination learning suggesting impaired hippocampal function Behavioural Brain Research 2001 118 1 53 60 (Pubitemid 32037113)
-
(2001)
Behavioural Brain Research
, vol.118
, Issue.1
, pp. 53-60
-
-
Hyde, L.A.1
Frisone, D.F.2
Crnic, L.S.3
-
65
-
-
0035022091
-
On the cause of mental retardation in Down syndrome: Extrapolation from full and segmental trisomy 16 mouse models
-
DOI 10.1016/S0926-6410(00)00074-4, PII S0926641000000744
-
Galdzicki Z., Siarey R., Pearce R., Stoll J., Rapoport S. I., On the cause of mental retardation in Down syndrome: extrapolation from full and segmental trisomy 16 mouse models Brain Research Reviews 2001 35 2 115 145 (Pubitemid 32411469)
-
(2001)
Brain Research Reviews
, vol.35
, Issue.2
, pp. 115-145
-
-
Galdzicki, Z.1
Siarey, R.2
Pearce, R.3
Stoll, J.4
Rapoport, S.I.5
-
66
-
-
79958203027
-
Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down Syndrome: Activation of 1-adrenergic receptor by xamoterol as a potential cognitive enhancer
-
Faizi M., Bader P. L., Tun C., Encarnacion A., Kleschevnikov A., Belichenko P., Saw N., Priestley M., Tsien R. W., Mobley W. C., Shamloo M., Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down Syndrome: activation of 1-adrenergic receptor by xamoterol as a potential cognitive enhancer Neurobiology of Disease 2011 43 2 397 413
-
(2011)
Neurobiology of Disease
, vol.43
, Issue.2
, pp. 397-413
-
-
Faizi, M.1
Bader, P.L.2
Tun, C.3
Encarnacion, A.4
Kleschevnikov, A.5
Belichenko, P.6
Saw, N.7
Priestley, M.8
Tsien, R.W.9
Mobley, W.C.10
Shamloo, M.11
-
67
-
-
36849017423
-
Age-related changes in memory and in acetylcholine functions in the hippocampus in the Ts65Dn mouse, a model of Down syndrome
-
DOI 10.1016/j.nlm.2007.05.007, PII S1074742707000846
-
Chang Q., Gold P. E., Age-related changes in memory and in acetylcholine functions in the hippocampus in the Ts65Dn mouse, a model of Down syndrome Neurobiology of Learning and Memory 2008 89 2 167 177 (Pubitemid 350235961)
-
(2008)
Neurobiology of Learning and Memory
, vol.89
, Issue.2
, pp. 167-177
-
-
Chang, Q.1
Gold, P.E.2
-
68
-
-
83055172862
-
On the promise of pharmacotherapies targeted at cognitive and neurodegenerative components of down syndrome
-
Costa A. C.S., On the promise of pharmacotherapies targeted at cognitive and neurodegenerative components of down syndrome Developmental Neuroscience 2011 33 5 414 427
-
(2011)
Developmental Neuroscience
, vol.33
, Issue.5
, pp. 414-427
-
-
Costa, A.C.S.1
-
69
-
-
43649094588
-
Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test
-
DOI 10.1038/sj.npp.1301535, PII 1301535
-
Costa A. C. S., Scott-McKean J. J., Stasko M. R., Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test Neuropsychopharmacology 2008 33 7 1624 1632 (Pubitemid 351684704)
-
(2008)
Neuropsychopharmacology
, vol.33
, Issue.7
, pp. 1624-1632
-
-
Costa, A.C.S.1
Scott-McKean, J.J.2
Stasko, M.R.3
-
70
-
-
79955723158
-
Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome
-
Lockrow J., Boger H., Bimonte-Nelson H., Granholm A.-C., Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome Behavioural Brain Research 2011 221 2 610 622
-
(2011)
Behavioural Brain Research
, vol.221
, Issue.2
, pp. 610-622
-
-
Lockrow, J.1
Boger, H.2
Bimonte-Nelson, H.3
Granholm, A.-C.4
-
71
-
-
77954972900
-
Memantine normalizes several phenotypic features in the Ts65Dn mouse model of down syndrome
-
Rueda N., Llorens-Martn M., Flrez J., Valdizn E., Banerjee P., Trejo J. L., Martnez-Cué C., Memantine normalizes several phenotypic features in the Ts65Dn mouse model of down syndrome Journal of Alzheimer's Disease 2010 21 1 277 290
-
(2010)
Journal of Alzheimer's Disease
, vol.21
, Issue.1
, pp. 277-290
-
-
Rueda, N.1
Llorens-Martn, M.2
Flrez, J.3
Valdizn, E.4
Banerjee, P.5
Trejo, J.L.6
Martnez-Cué, C.7
-
72
-
-
33746452680
-
Altered signaling pathways underlying abnormal hippocampal synaptic plasticity in the Ts65Dn mouse model of Down syndrome
-
DOI 10.1111/j.1471-4159.2006.03971.x
-
Siarey R. J., Kline-Burgess A., Cho M., Balbo A., Best T. K., Harashima C., Klann E., Galdzicki Z., Altered signaling pathways underlying abnormal hippocampal synaptic plasticity in the Ts65Dn mouse model of Down syndrome Journal of Neurochemistry 2006 98 4 1266 1277 (Pubitemid 44127800)
-
(2006)
Journal of Neurochemistry
, vol.98
, Issue.4
, pp. 1266-1277
-
-
Siarey, R.J.1
Kline-Burgess, A.2
Cho, M.3
Balbo, A.4
Best, T.K.5
Harashima, C.6
Klann, E.7
Galdzicki, Z.8
-
73
-
-
0033646677
-
Sequence of cognitive decline in dementia in adults with Down's syndrome
-
Devenny D. A., Krinsky-McHale S. J., Sersen G., Silverman W. P., Sequence of cognitive decline in dementia in adults with Down's syndrome Journal of Intellectual Disability Research 2000 44 6 654 665
-
(2000)
Journal of Intellectual Disability Research
, vol.44
, Issue.6
, pp. 654-665
-
-
Devenny, D.A.1
Krinsky-Mchale, S.J.2
Sersen, G.3
Silverman, W.P.4
-
74
-
-
45249087489
-
Functional consequences of locus coeruleus degeneration in Alzheimer's disease
-
DOI 10.2174/156720508784533286
-
Weinshenker D., Functional consequences of locus coeruleus degeneration in Alzheimer's disease Current Alzheimer Research 2008 5 3 342 345 (Pubitemid 351840281)
-
(2008)
Current Alzheimer Research
, vol.5
, Issue.3
, pp. 342-345
-
-
Weinshenker, D.1
-
75
-
-
0036546148
-
Noradrenergic Depletion Potentiates β-Amyloid-Induced Cortical Inflammation: Implications for Alzheimer's Disease
-
Heneka M. T., Galea E., Gavriluyk V., Dumitrescu-Ozimek L., Daeschner J., O'Banion M. K., Weinberg G., Klockgether T., Feinstein D. L., Noradrenergic depletion potentiates -amyloid-induced cortical inflammation: implications for Alzheimer's disease Journal of Neuroscience 2002 22 7 2434 2442 (Pubitemid 37465791)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.7
, pp. 2434-2442
-
-
Heneka, M.T.1
Galea, E.2
Gavriluyk, V.3
Dumitrescu-Ozimek, L.4
Daeschner, J.5
O'Banion, M.K.6
Weinberg, G.7
Klockgether, T.8
Feinstein, D.L.9
-
76
-
-
77950547609
-
Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine
-
Heneka M. T., Nadrigny F., Regen T., Martinez-Hernandez A., Dumitrescu-Ozimek L., Terwel D., Jardanhazi-Kurutz D., Walter J., Kirchhoff F., Hanisch U. K., Kummer M. P., Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine Proceedings of the National Academy of Sciences of the United States of America 2010 107 13 6058 6063
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, Issue.13
, pp. 6058-6063
-
-
Heneka, M.T.1
Nadrigny, F.2
Regen, T.3
Martinez-Hernandez, A.4
Dumitrescu-Ozimek, L.5
Terwel, D.6
Jardanhazi-Kurutz, D.7
Walter, J.8
Kirchhoff, F.9
Hanisch, U.K.10
Kummer, M.P.11
-
77
-
-
77956225289
-
Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits
-
Jardanhazi-Kurutz D., Kummer M. P., Terwel D., Vogel K., Dyrks T., Thiele A., Heneka M. T., Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits Neurochemistry International 2010 57 4 375 382
-
(2010)
Neurochemistry International
, vol.57
, Issue.4
, pp. 375-382
-
-
Jardanhazi-Kurutz, D.1
Kummer, M.P.2
Terwel, D.3
Vogel, K.4
Dyrks, T.5
Thiele, A.6
Heneka, M.T.7
-
78
-
-
21744440927
-
The neurotransmitter noradrenaline rescues septal cholinergic neurons in culture from degeneration caused by low-level oxidative stress
-
DOI 10.1124/mol.104.007864
-
Traver S., Salthun-Lassalle B., Marien M., Hirsch E. C., Colpaert F., Michel P. P., The neurotransmitter noradrenaline rescues septal cholinergic neurons in culture from degeneration caused by low-level oxidative stress Molecular Pharmacology 2005 67 6 1882 1891 (Pubitemid 41007770)
-
(2005)
Molecular Pharmacology
, vol.67
, Issue.6
, pp. 1882-1891
-
-
Traver, S.1
Salthun-Lassalle, B.2
Marien, M.3
Hirsch, E.C.4
Colpaert, F.5
Michel, P.P.6
-
79
-
-
0031980889
-
Pharmacology of sensory stimulation-evoked increases in frontal cortical acetylcholine release
-
DOI 10.1016/S0306-4522(97)00546-0, PII S0306452297005460
-
Acquas E., Wilson C., Fibiger H. C., Pharmacology of sensory stimulation-evoked increases in frontal cortical acetylcholine release Neuroscience 1998 85 1 73 83 (Pubitemid 28228416)
-
(1998)
Neuroscience
, vol.85
, Issue.1
, pp. 73-83
-
-
Acquas, E.1
Wilson, C.2
Fibiger, H.C.3
-
80
-
-
34548228945
-
Norepinephrine and the dentate gyrus
-
DOI 10.1016/S0079-6123(07)63018-0, PII S0079612307630180, The Dentate Gyrus: A Comprehensive Guide to Structure, Function, and Clinical Implications
-
Harley C. W., Norepinephrine and the dentate gyrus Progress in Brain Research 2007 163 299 318 (Pubitemid 47321442)
-
(2007)
Progress in Brain Research
, vol.163
, pp. 299-318
-
-
Harley, C.W.1
-
81
-
-
32544449785
-
Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice
-
DOI 10.1523/JNEUROSCI.4236-05.2006
-
Heneka M. T., Ramanathan M., Jacobs A. H., Dumitrescu-Ozimek L., Bilkei-Gorzo A., Debeir T., Sastre M., Galldiks N., Zimmer A., Hoehn M., Heiss W. D., Klockgether T., Staufenbiel M., Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice Journal of Neuroscience 2006 26 5 1343 1354 (Pubitemid 43237005)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.5
, pp. 1343-1354
-
-
Heneka, M.T.1
Ramanathan, M.2
Jacobs, A.H.3
Dumitrescu-Ozimek, L.4
Bilkei-Gorzo, A.5
Debeir, T.6
Sastre, M.7
Galldiks, N.8
Zimmer, A.9
Hoehn, M.10
Heiss, W.-D.11
Klockgether, T.12
Staufenbiel, M.13
-
82
-
-
34249281253
-
Noradrenaline deficiency in brain increases β-amyloid plaque burden in an animal model of Alzheimer's disease
-
DOI 10.1016/j.neurobiolaging.2006.06.003, PII S0197458006001977
-
Kalinin S., Gavrilyuk V., Polak P. E., Vasser R., Zhao J., Heneka M. T., Feinstein D. L., Noradrenaline deficiency in brain increases -amyloid plaque burden in an animal model of Alzheimer's disease Neurobiology of Aging 2007 28 8 1206 1214 (Pubitemid 46810064)
-
(2007)
Neurobiology of Aging
, vol.28
, Issue.8
, pp. 1206-1214
-
-
Kalinin, S.1
Gavrilyuk, V.2
Polak, P.E.3
Vasser, R.4
Zhao, J.5
Heneka, M.T.6
Feinstein, D.L.7
-
83
-
-
27644444245
-
The PDAPP mouse model of Alzheimer's disease: Locus coeruleus neuronal shrinkage
-
DOI 10.1002/cne.20744
-
Gekman D. C., Nelson O., Liang F., Liang C. L., Games D., The PDAPP mouse model of Alzheimer's disease: Locus coeruleus neuronal shrinkage Journal of Comparative Neurology 2005 492 4 469 476 (Pubitemid 41572463)
-
(2005)
Journal of Comparative Neurology
, vol.492
, Issue.4
, pp. 469-476
-
-
Gekman, D.C.1
Nelson, O.2
Liang, F.3
Liang, C.-L.4
Games, D.5
-
84
-
-
0026492005
-
Disease-specific patterns of locus coeruleus cell loss
-
German D. C., Manaye K. F., White C. L., Woodward D. J., McIntire D. D., Smith W. K., Kalaria R. N., Mann D. M. A., Disease-specific patterns of locus coeruleus cell loss Annals of Neurology 1992 32 5 667 676
-
(1992)
Annals of Neurology
, vol.32
, Issue.5
, pp. 667-676
-
-
German, D.C.1
Manaye, K.F.2
White, C.L.3
Woodward, D.J.4
McIntire, D.D.5
Smith, W.K.6
Kalaria, R.N.7
Mann, D.M.A.8
-
86
-
-
0037337815
-
Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases
-
DOI 10.1001/archneur.60.3.337
-
Zarow C., Lyness S. A., Mortimer J. A., Chui H. C., Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases Archives of Neurology 2003 60 3 337 341 (Pubitemid 36314358)
-
(2003)
Archives of Neurology
, vol.60
, Issue.3
, pp. 337-341
-
-
Zarow, C.1
Lyness, S.A.2
Mortimer, J.A.3
Chui, H.C.4
-
87
-
-
79960121463
-
Differential degeneration of the locus coeruleus in dementia subtypes
-
Brunnstrm H., Friberg N., Lindberg E., Englund E., Differential degeneration of the locus coeruleus in dementia subtypes Clinical Neuropathology 2011 30 3 104 110
-
(2011)
Clinical Neuropathology
, vol.30
, Issue.3
, pp. 104-110
-
-
Brunnstrm, H.1
Friberg, N.2
Lindberg, E.3
Englund, E.4
-
88
-
-
61649118193
-
Atomoxetine for the treatment of executive dysfunction in Parkinson's disease: A pilot open-label study
-
Marsh L., Biglan K., Gerstenhaber M., Williams J. R., Atomoxetine for the treatment of executive dysfunction in Parkinson's disease: a pilot open-label study Movement Disorders 2009 24 2 277 282
-
(2009)
Movement Disorders
, vol.24
, Issue.2
, pp. 277-282
-
-
Marsh, L.1
Biglan, K.2
Gerstenhaber, M.3
Williams, J.R.4
-
89
-
-
69449085737
-
Atomoxetine augmentation of cholinesterase inhibitor therapy in patients with alzheimer disease: 6-month, randomized, double-blind, placebo-controlled, parallel-trial study
-
Mohs R. C., Shiovitz T. M., Tariot P. N., Porsteinsson A. P., Baker K. D., Feldman P. D., Atomoxetine augmentation of cholinesterase inhibitor therapy in patients with alzheimer disease: 6-month, randomized, double-blind, placebo-controlled, parallel-trial study American Journal of Geriatric Psychiatry 2009 17 9 752 759
-
(2009)
American Journal of Geriatric Psychiatry
, vol.17
, Issue.9
, pp. 752-759
-
-
Mohs, R.C.1
Shiovitz, T.M.2
Tariot, P.N.3
Porsteinsson, A.P.4
Baker, K.D.5
Feldman, P.D.6
-
91
-
-
33644869901
-
Inflammation and neurodegenerative diseases
-
Griffin W. S. T., Inflammation and neurodegenerative diseases American Journal of Clinical Nutrition 2006 83 2 470S 474S (Pubitemid 44713221)
-
(2006)
American Journal of Clinical Nutrition
, vol.83
, Issue.2
-
-
Griffin, W.S.T.1
-
92
-
-
11444256801
-
Glia and their cytokines in progression of neurodegeneration
-
DOI 10.1016/j.neurobiolaging.2004.05.010, PII S0197458004002921, Developmental Origins of Aging in the Brain and Blood Vessels
-
Mrak R. E., Griffin W. S. T., Glia and their cytokines in progression of neurodegeneration Neurobiology of Aging 2005 26 3 349 354 (Pubitemid 40082718)
-
(2005)
Neurobiology of Aging
, vol.26
, Issue.3
, pp. 349-354
-
-
Mrak, R.E.1
Griffin, W.S.T.2
-
93
-
-
0030855888
-
Serum interleukin-6 levels correlate with the severity of dementia in down syndrome and in Alzheimer's disease
-
Klmn J., Juhsz A., Laird G., Dickens P., Jrdnhzy T., Rimanczy., Boncz I., Parry-Jones W. L.I., Janka Z., Serum interleukin-6 levels correlate with the severity of dementia in down syndrome and in Alzheimer's disease Acta Neurologica Scandinavica 1997 96 4 236 240 (Pubitemid 27402491)
-
(1997)
Acta Neurologica Scandinavica
, vol.96
, Issue.4
, pp. 236-240
-
-
Kalman, J.1
Juhasz, A.2
Laird, G.3
Dickens, P.4
Jardanhazy, T.5
Rimanoczy, A.6
Boncz, I.7
Parry-Jones, W.L.I.8
Janka, Z.9
-
94
-
-
24944524929
-
Brain cholinergic vulnerability: Relevance to behavior and disease
-
DOI 10.1016/j.bcp.2005.05.019, PII S0006295205003503
-
McKinney M., Brain cholinergic vulnerability: relevance to behavior and disease Biochemical Pharmacology 2005 70 8 1115 1124 (Pubitemid 41317506)
-
(2005)
Biochemical Pharmacology
, vol.70
, Issue.8
, pp. 1115-1124
-
-
McKinney, M.1
-
95
-
-
0038582538
-
Tumor necrosis factor-α triggers cell death of sensitized potassium chloride-stimulated cholinergic neurons
-
DOI 10.1016/S0169-328X(03)00092-5
-
Zassler B., Weis C., Humpel C., Tumor necrosis factor- triggers cell death of sensitized potassium chloride-stimulated cholinergic neurons Molecular Brain Research 2003 113 1-2 78 85 (Pubitemid 36579069)
-
(2003)
Molecular Brain Research
, vol.113
, Issue.1-2
, pp. 78-85
-
-
Zassler, B.1
Weis, C.2
Humpel, C.3
-
96
-
-
41749124775
-
Microglia-neuron interaction in inflammatory and degenerative diseases: Role of cholinergic and noradrenergic systems
-
DOI 10.2174/187152707783399193
-
Carnevale D., De Simone R., Minghetti L., Microglia-neuron interaction in inflammatory and degenerative diseases: role of cholinergic and noradrenergic systems CNS and Neurological Disorders 2007 6 6 388 397 (Pubitemid 351486253)
-
(2007)
CNS and Neurological Disorders - Drug Targets
, vol.6
, Issue.6
, pp. 388-397
-
-
Carnevale, D.1
De Simone, R.2
Minghetti, L.3
-
97
-
-
0023026959
-
Number of neurons in nucleus locus ceruleus in demented and non-demented patients: Rapid estimation and correlated parameters
-
DOI 10.1016/0197-4580(86)90010-2
-
Bondareff W., Mountjoy C. Q., Number of neurons in nucleus locus ceruleus in demented and non-demented patients: rapid estimation and correlated parameters Neurobiology of Aging 1986 7 4 297 300 (Pubitemid 17172372)
-
(1986)
Neurobiology of Aging
, vol.7
, Issue.4
, pp. 297-300
-
-
Bondareff, W.1
Mountjoy, C.Q.2
-
98
-
-
0024825268
-
Neuropathology of aminergic nuclei in Alzheimer's disease
-
Zweig R. M., Ross C. A., Hedreen J. C., Steele C., Cardillo J. E., Whitehouse P. J., Folstein M. F., Price D. L., Neuropathology of aminergic nuclei in Alzheimer's disease Progress in Clinical and Biological Research 1989 317 353 365
-
(1989)
Progress in Clinical and Biological Research
, vol.317
, pp. 353-365
-
-
Zweig, R.M.1
Ross, C.A.2
Hedreen, J.C.3
Steele, C.4
Cardillo, J.E.5
Whitehouse, P.J.6
Folstein, M.F.7
Price, D.L.8
-
99
-
-
0035993240
-
Noradrenergic regulation of inflammatory gene expression in brain
-
Feinstein D. L., Heneka M. T., Gavrilyuk V., Dello Russo C., Weinberg G., Galea E., Noradrenergic regulation of inflammatory gene expression in brain Neurochemistry International 2002 41 5 357 365
-
(2002)
Neurochemistry International
, vol.41
, Issue.5
, pp. 357-365
-
-
Feinstein, D.L.1
Heneka, M.T.2
Gavrilyuk, V.3
Dello Russo, C.4
Weinberg, G.5
Galea, E.6
-
100
-
-
37849050242
-
Neurotrophic factors in Alzheimer's disease: Role of axonal transport
-
Schindowski K., Belarbi K., Buée L., Neurotrophic factors in Alzheimer's disease: role of axonal transport Genes, Brain and Behavior 2008 7 1 43 56
-
(2008)
Genes, Brain and Behavior
, vol.7
, Issue.1
, pp. 43-56
-
-
Schindowski, K.1
Belarbi, K.2
Buée, L.3
-
101
-
-
0346849771
-
Trafficking the NGF signal: Implications for normal and degenerating neurons
-
Delcroix J. D., Valletta J., Wu C., Howe C. L., Lai C. F., Cooper J. D., Belichenko P. V., Salehi A., Mobley W. C., Trafficking the NGF signal: implications for normal and degenerating neurons Progress in Brain Research 2004 146 3 23 (Pubitemid 37541372)
-
(2004)
Progress in Brain Research
, vol.146
, pp. 3-23
-
-
Delcroix, J.-D.1
Valletta, J.2
Wu, C.3
Howe, C.L.4
Lai, C.-F.5
Cooper, J.D.6
Belichenko, P.V.7
Salehi, A.8
Mobley, W.C.9
-
102
-
-
16844377812
-
The role of nerve growth factor receptors in cholinergic basal forebrain degeneration in prodromal Alzheimer disease
-
Counts S. E., Mufson E. J., The role of nerve growth factor receptors in cholinergic basal forebrain degeneration in prodromal Alzheimer disease Journal of Neuropathology and Experimental Neurology 2005 64 4 263 272 (Pubitemid 40489553)
-
(2005)
Journal of Neuropathology and Experimental Neurology
, vol.64
, Issue.4
, pp. 263-272
-
-
Counts, S.E.1
Mufson, E.J.2
-
103
-
-
33750963813
-
Nerve growth factor in treatment and pathogenesis of Alzheimer's disease
-
DOI 10.1016/j.pneurobio.2006.09.001, PII S0301008206001092
-
Williams B. J., Eriksdotter-Jonhagen M., Granholm A. C., Nerve growth factor in treatment and pathogenesis of Alzheimer's disease Progress in Neurobiology 2006 80 3 114 128 (Pubitemid 44739167)
-
(2006)
Progress in Neurobiology
, vol.80
, Issue.3
, pp. 114-128
-
-
Williams, B.J.1
Eriksdotter-Jonhagen, M.2
Granholm, A.-C.3
-
104
-
-
0029039162
-
Nerve growth factor in Alzheimer's disease: Defective retrograde transport to nucleus basalis
-
Mufson E. J., Conner J. M., Kordower J. H., Nerve growth factor in Alzheimer's disease: defective retrograde transport to nucleus basalis NeuroReport 1995 6 7 1063 1066
-
(1995)
NeuroReport
, vol.6
, Issue.7
, pp. 1063-1066
-
-
Mufson, E.J.1
Conner, J.M.2
Kordower, J.H.3
-
105
-
-
33846574233
-
Age-dependent loss of NGF signaling in the rat basal forebrain is due to disrupted MAPK activation
-
DOI 10.1016/j.neulet.2006.11.040, PII S0304394006012717
-
Williams B., Granholm A. C., Sambamurti K., Age-dependent loss of NGF signaling in the rat basal forebrain is due to disrupted MAPK activation Neuroscience Letters 2007 413 2 110 114 (Pubitemid 46177399)
-
(2007)
Neuroscience Letters
, vol.413
, Issue.2
, pp. 110-114
-
-
Williams, B.1
Granholm, A.-C.2
Sambamurti, K.3
-
106
-
-
76549096350
-
Alzheimer's-related endosome dysfunction in Down syndrome is A -independent but requires APP and is reversed by BACE-1 inhibition
-
Jiang Y., Mullaney K. A., Peterhoff C. M., Che S., Schmidt S. D., Boyer-Boiteau A., Ginsberg S. D., Cataldo A. M., Mathews P. M., Nixon R. A., Alzheimer's-related endosome dysfunction in Down syndrome is A -independent but requires APP and is reversed by BACE-1 inhibition Proceedings of the National Academy of Sciences of the United States of America 2010 107 4 1630 1635
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, Issue.4
, pp. 1630-1635
-
-
Jiang, Y.1
Mullaney, K.A.2
Peterhoff, C.M.3
Che, S.4
Schmidt, S.D.5
Boyer-Boiteau, A.6
Ginsberg, S.D.7
Cataldo, A.M.8
Mathews, P.M.9
Nixon, R.A.10
-
107
-
-
78049427173
-
Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression
-
Ginsberg S. D., Alldred M. J., Counts S. E., Cataldo A. M., Neve R. L., Jiang Y., Wuu J., Chao M. V., Mufson E. J., Nixon R. A., Che S., Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression Biological Psychiatry 2010 68 10 885 893
-
(2010)
Biological Psychiatry
, vol.68
, Issue.10
, pp. 885-893
-
-
Ginsberg, S.D.1
Alldred, M.J.2
Counts, S.E.3
Cataldo, A.M.4
Neve, R.L.5
Jiang, Y.6
Wuu, J.7
Chao, M.V.8
Mufson, E.J.9
Nixon, R.A.10
Che, S.11
-
108
-
-
70349241688
-
Multiple functions of precursor BDNF to CNS neurons: Negative regulation of neurite growth, spine formation and cell survival
-
ARTICLE 27
-
Koshimizu H., Kiyosue K., Hara T., Hazama S., Suzuki S., Uegaki K., Nagappan G., Zaitsev E., Hirokawa T., Tatsu Y., Ogura A., Lu B., Kojima M., Multiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival Molecular Brain 2009 2 1, article 27
-
(2009)
Molecular Brain
, vol.2
, pp. 1
-
-
Koshimizu, H.1
Kiyosue, K.2
Hara, T.3
Hazama, S.4
Suzuki, S.5
Uegaki, K.6
Nagappan, G.7
Zaitsev, E.8
Hirokawa, T.9
Tatsu, Y.10
Ogura, A.11
Lu, B.12
Kojima, M.13
-
109
-
-
0036047652
-
Neurotrophic factors and Alzheimer's disease: Are we focusing on the wrong molecule?
-
Fahnestock M., Garzon D., Holsinger R. M.D., Michalski B., Neurotrophic factors and Alzheimer's disease: are we focusing on the wrong molecule? Journal of Neural Transmission 2002 62, supplement 241 252 (Pubitemid 37046668)
-
(2002)
Journal of Neural Transmission, Supplement
, Issue.62
, pp. 241-252
-
-
Fahnestock, M.1
Garzon, D.2
Holsinger, R.M.D.3
Michalski, B.4
-
110
-
-
84856087357
-
Cooperation between cholinergic and glutamatergic receptors are essential to induce BDNF-dependent long-lasting memory storage
-
Navakkode S., Korte M., Cooperation between cholinergic and glutamatergic receptors are essential to induce BDNF-dependent long-lasting memory storage Hippocampus 2012 22 22 335 346
-
(2012)
Hippocampus
, vol.22
, Issue.22
, pp. 335-346
-
-
Navakkode, S.1
Korte, M.2
-
111
-
-
77649327305
-
Age-related changes in plasma levels of BDNF in Down syndrome patients
-
Dogliotti G., Galliera E., Licastro F., Corsi M. M., Age-related changes in plasma levels of BDNF in Down syndrome patients Immunity and Ageing 2010 7, article 2
-
(2010)
Immunity and Ageing
, vol.72
-
-
Dogliotti, G.1
Galliera, E.2
Licastro, F.3
Corsi, M.M.4
-
112
-
-
79960832275
-
Involvement of BDNF in age-dependent alterations in the hippocampus
-
von Bohlen O., Halbach, Involvement of BDNF in age-dependent alterations in the hippocampus Frontiers in Aging Neuroscience 2010 2, article 36
-
(2010)
Frontiers in Aging Neuroscience
, vol.236
-
-
Von Bohlen, O.1
Halbach2
-
113
-
-
77951295329
-
Exercise and time-dependent benefits to learning and memory
-
Berchtold N. C., Castello N., Cotman C. W., Exercise and time-dependent benefits to learning and memory Neuroscience 2010 167 3 588 597
-
(2010)
Neuroscience
, vol.167
, Issue.3
, pp. 588-597
-
-
Berchtold, N.C.1
Castello, N.2
Cotman, C.W.3
-
114
-
-
20444398484
-
Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus
-
DOI 10.1016/j.neuroscience.2005.03.026, PII S0306452205003659
-
Berchtold N. C., Chinn G., Chou M., Kesslak J. P., Cotman C. W., Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus Neuroscience 2005 133 3 853 861 (Pubitemid 40798336)
-
(2005)
Neuroscience
, vol.133
, Issue.3
, pp. 853-861
-
-
Berchtold, N.C.1
Chinn, G.2
Chou, M.3
Kesslak, J.P.4
Cotman, C.W.5
-
115
-
-
79151472357
-
Treadmill exercise prevents decline in spatial learning and memory in APP/PS1 transgenic mice through improvement of hippocampal long-term potentiation
-
Liu H. -L., Zhao G., Cai K., Zhao H. -H., Shi L. -D., Treadmill exercise prevents decline in spatial learning and memory in APP/PS1 transgenic mice through improvement of hippocampal long-term potentiation Behavioural Brain Research 2011 218 2 308 314
-
(2011)
Behavioural Brain Research
, vol.218
, Issue.2
, pp. 308-314
-
-
Liu, H.-L.1
Zhao, G.2
Cai, K.3
Zhao, H.-H.4
Shi, L.-D.5
-
116
-
-
44649117985
-
Upregulation of hippocampal TrkB and synaptotagmin is involved in treadmill exercise-enhanced aversive memory in mice
-
Liu Y. F., Chen H. I., Yu L., Kuo Y. M., Wu F. S., Chuang J. I., Liao P. C., Jen C. J., Upregulation of hippocampal TrkB and synaptotagmin is involved in treadmill exercise-enhanced aversive memory in mice Neurobiology of Learning and Memory 2008 90 1 81 89
-
(2008)
Neurobiology of Learning and Memory
, vol.90
, Issue.1
, pp. 81-89
-
-
Liu, Y.F.1
Chen, H.I.2
Yu, L.3
Kuo, Y.M.4
Wu, F.S.5
Chuang, J.I.6
Liao, P.C.7
Jen, C.J.8
-
117
-
-
67649774919
-
Exercise improves cognition and hippocampal plasticity in APOE {lunate}4 mice
-
Nichol K., Deeny S. P., Seif J., Camaclang K., Cotman C. W., Exercise improves cognition and hippocampal plasticity in APOE {lunate}4 mice Alzheimer's and Dementia 2009 5 4 287 294
-
(2009)
Alzheimer's and Dementia
, vol.5
, Issue.4
, pp. 287-294
-
-
Nichol, K.1
Deeny, S.P.2
Seif, J.3
Camaclang, K.4
Cotman, C.W.5
-
118
-
-
15244353111
-
Regulation of trophic factor expression by innervating target regions in intraocular double transplants
-
Willis L., Quintero E. M., Nelson M., Granholm A. C., Regulation of trophic factor expression by innervating target regions in intraocular double transplants Cell Transplantation 2005 14 1 21 29 (Pubitemid 40387675)
-
(2005)
Cell Transplantation
, vol.14
, Issue.1
, pp. 21-29
-
-
Willis, L.1
Quintero, E.M.2
Nelson, M.3
Granholm, A.-Ch.4
-
119
-
-
77950652321
-
Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity
-
Counts S. E., Mufson E. J., Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity Journal of Neurochemistry 2010 113 3 649 660
-
(2010)
Journal of Neurochemistry
, vol.113
, Issue.3
, pp. 649-660
-
-
Counts, S.E.1
Mufson, E.J.2
-
120
-
-
69549103145
-
Recent advances in our understanding of neurodegeneration
-
Jellinger K. A., Recent advances in our understanding of neurodegeneration Journal of Neural Transmission 2009 116 9 1111 1162
-
(2009)
Journal of Neural Transmission
, vol.116
, Issue.9
, pp. 1111-1162
-
-
Jellinger, K.A.1
-
121
-
-
58149396679
-
Oxidative stress and cognitive ability in adults with Down syndrome
-
Strydom A., Dickinson M. J., Shende S., Pratico D., Walker Z., Oxidative stress and cognitive ability in adults with Down syndrome Progress in Neuro-Psychopharmacology and Biological Psychiatry 2009 33 1 76 80
-
(2009)
Progress in Neuro-Psychopharmacology and Biological Psychiatry
, vol.33
, Issue.1
, pp. 76-80
-
-
Strydom, A.1
Dickinson, M.J.2
Shende, S.3
Pratico, D.4
Walker, Z.5
-
122
-
-
73849112556
-
Structural features of ischemic damage in the hippocampus
-
Nikonenko A. G., Radenovic L., Andjus P. R., Skibo G. G., Structural features of ischemic damage in the hippocampus Anatomical Record 2009 292 12 1914 1921
-
(2009)
Anatomical Record
, vol.292
, Issue.12
, pp. 1914-1921
-
-
Nikonenko, A.G.1
Radenovic, L.2
Andjus, P.R.3
Skibo, G.G.4
-
123
-
-
78649516312
-
Oxidative stress in Alzheimer's disease hippocampus: A topographical study
-
Cruz-Snchez F. F., Girons X., Ortega A., Alameda F., Lafuente J. V., Oxidative stress in Alzheimer's disease hippocampus: a topographical study Journal of the Neurological Sciences 2010 299 1-2 163 167
-
(2010)
Journal of the Neurological Sciences
, vol.299
, Issue.12
, pp. 163-167
-
-
Cruz-Snchez, F.F.1
Girons, X.2
Ortega, A.3
Alameda, F.4
Lafuente, J.V.5
-
124
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura A., Perry G., Aliev G., Hirai K., Takeda A., Balraj E. K., Jones P. K., Ghanbari H., Wataya T., Shimohama S., Chiba S., Atwood C. S., Petersen R. B., Smith M. A., Oxidative damage is the earliest event in Alzheimer disease Journal of Neuropathology and Experimental Neurology 2001 60 8 759 767 (Pubitemid 32678256)
-
(2001)
Journal of Neuropathology and Experimental Neurology
, vol.60
, Issue.8
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
Hirai, K.4
Takeda, A.5
Balraj, E.K.6
Jones, P.K.7
Ghanbari, H.8
Wataya, T.9
Shimohama, S.10
Chiba, S.11
Atwood, C.S.12
Petersen, R.B.13
Smith, M.A.14
-
125
-
-
0033758324
-
Neuronal oxidative stress precedes amyloid- deposition in down syndrome
-
Nunomura A., Perry G., Pappolla M. A., Friedland R. P., Hirai K., Chiba S., Smith M. A., Neuronal oxidative stress precedes amyloid- deposition in down syndrome Journal of Neuropathology and Experimental Neurology 2000 59 11 1011 1017
-
(2000)
Journal of Neuropathology and Experimental Neurology
, vol.59
, Issue.11
, pp. 1011-1017
-
-
Nunomura, A.1
Perry, G.2
Pappolla, M.A.3
Friedland, R.P.4
Hirai, K.5
Chiba, S.6
Smith, M.A.7
-
126
-
-
69449096141
-
Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease
-
Massaad C. A., Washington T. M., Pautler R. G., Klann E., Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease Proceedings of the National Academy of Sciences of the United States of America 2009 106 32 13576 13581
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.32
, pp. 13576-13581
-
-
Massaad, C.A.1
Washington, T.M.2
Pautler, R.G.3
Klann, E.4
-
127
-
-
0037096203
-
Why does SOD overexpression sometimes enhance, sometimes decrease, hydrogen peroxide production? A minimalist explanation
-
DOI 10.1016/S0891-5849(02)00861-4, PII S0891584902008614
-
Gardner R., Salvador A., Moradas-Ferreira P., Why does SOD overexpression sometimes enhance, sometimes decrease, hydrogen peroxide production? A minimalist explanation Free Radical Biology and Medicine 2002 32 12 1351 1357 (Pubitemid 34607639)
-
(2002)
Free Radical Biology and Medicine
, vol.32
, Issue.12
, pp. 1351-1357
-
-
Gardner, R.1
Salvador, A.2
Moradas-Ferreira, P.3
-
128
-
-
0035233637
-
Protein levels of human peroxiredoxin subtypes in brains of patients with Alzheimer's disease and Down Syndrome
-
Kim S. H., Fountoulakis M., Cairns N., Lubec G., Protein levels of human peroxiredoxin subtypes in brains of patients with Alzheimer's disease and Down Syndrome Journal of Neural Transmission 2001 61, supplement 223 235 (Pubitemid 38085085)
-
(2001)
Journal of Neural Transmission, Supplement
, Issue.61
, pp. 223-235
-
-
Kim, S.H.1
Fountoulakis, M.2
Cairns, N.3
Lubec, G.4
-
129
-
-
57649221161
-
Evidence of oxidative stress in Alzheimer's disease brain and antioxidant therapy: Lights and shadows
-
Pratic D., Evidence of oxidative stress in Alzheimer's disease brain and antioxidant therapy: lights and shadows Annals of the New York Academy of Sciences 2008 1147 70 78
-
(2008)
Annals of the New York Academy of Sciences
, vol.1147
, pp. 70-78
-
-
Pratic, D.1
-
130
-
-
40949121945
-
Supplementation with antioxidants and folinic acid for children with Down's syndrome: Randomised controlled trial
-
DOI 10.1136/bmj.39465.544028.AE
-
Ellis J. M., Hooi K. T., Gilbert R. E., Muller D. P. R., Henley W., Moy R., Pumphrey R., Ani C., Davies S., Edwards V., Green H., Salt A., Logan S., Supplementation with antioxidants and folinic acid for children with Down's syndrome: randomised controlled trial British Medical Journal 2008 336 7644 594 597 (Pubitemid 351439516)
-
(2008)
BMJ
, vol.336
, Issue.7644
, pp. 594-597
-
-
Ellis, J.M.1
Hooi, K.T.2
Gilbert, R.E.3
Muller, D.P.R.4
Henley, W.5
Moy, R.6
Pumphrey, R.7
Ani, C.8
Davies, S.9
Edwards, V.10
Green, H.11
Salt, A.12
Logan, S.13
-
131
-
-
62049085639
-
Cholinergic degeneration and memory loss delayed by vitamin e in a Down syndrome mouse model
-
Lockrow J., Prakasam A., Huang P., Bimonte-Nelson H., Sambamurti K., Granholm A. C., Cholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model Experimental Neurology 2009 216 2 278 289
-
(2009)
Experimental Neurology
, vol.216
, Issue.2
, pp. 278-289
-
-
Lockrow, J.1
Prakasam, A.2
Huang, P.3
Bimonte-Nelson, H.4
Sambamurti, K.5
Granholm, A.C.6
-
132
-
-
34249672242
-
Aβ oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine
-
DOI 10.1074/jbc.M607483200
-
De Felice F. G., Velasco P. T., Lambert M. P., Viola K., Fernandez S. J., Ferreira S. T., Klein W. L., A oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine Journal of Biological Chemistry 2007 282 15 11590 11601 (Pubitemid 47100810)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.15
, pp. 11590-11601
-
-
De Felice, F.G.1
Velasco, P.T.2
Lambert, M.P.3
Viola, K.4
Fernandez, S.J.5
Ferreira, S.T.6
Klein, W.L.7
-
133
-
-
0034641936
-
Apoptosis in the nervous system
-
Yuan J., Yankner B. A., Apoptosis in the nervous system Nature 2000 407 6805 802 809
-
(2000)
Nature
, vol.407
, Issue.6805
, pp. 802-809
-
-
Yuan, J.1
Yankner, B.A.2
-
134
-
-
34447306022
-
RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress: A potential pathogenic process in neurodegeneration
-
DOI 10.1093/hmg/ddm049
-
Porta S., Serra S. A., Huch M., Valverde M. A., Llorens F., Estivill X., Arbonés M. L., Mart E., RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress: a potential pathogenic process in neurodegeneration Human Molecular Genetics 2007 16 9 1039 1050 (Pubitemid 47062725)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.9
, pp. 1039-1050
-
-
Porta, S.1
Serra, S.A.2
Huch, M.3
Valverde, M.A.4
Llorens, F.5
Estivill, X.6
Arbones, M.L.7
Marti, E.8
-
135
-
-
26444452685
-
Atomoxetine and stroop task performance in adult attention-deficit/ hyperactivity disorder
-
DOI 10.1089/cap.2005.15.664
-
Faraone S. V., Biederman J., Spencer T., Michelson D., Adler L., Reimherr F., Seidman L., Atomoxetine and stroop task performance in adult attention-deficit/ hyperactivity disorder Journal of Child and Adolescent Psychopharmacology 2005 15 4 664 670 (Pubitemid 41434370)
-
(2005)
Journal of Child and Adolescent Psychopharmacology
, vol.15
, Issue.4
, pp. 664-670
-
-
Faraone, S.V.1
Biederman, J.2
Spencer, T.3
Michelson, D.4
Adler, L.5
Reimherr, F.6
Seidman, L.7
|