On the cause of mental retardation in Down syndrome: Extrapolation from full and segmental trisomy 16 mouse models

Brain Research Reviews

Volumn 35, Issue 2, 2001, Pages 115-145

  Galdzicki, Zygmunt ^a,b   Siarey, Richard ^a   Pearce, Rosalyn ^a   Stoll, James ^a   Rapoport, Stanley I ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Action potential; Brain; Conduction; Dorsal root ganglion; Down syndrome; Electrical properties; Hippocampus; Long term depression; Long term potentiation; Mental retardation; Mouse; Nerve growth factor; Neurodevelopment; Patch clamp; Trisomy 16; Trisomy 21

Indexed keywords

CALCIUM ION; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUCOSE; N METHYL DEXTRO ASPARTIC ACID; NERVE GROWTH FACTOR; PHOSPHATIDYLINOSITIDE; POTASSIUM ION; PROTEIN KINASE C; SODIUM ION;

BRAIN SIZE; CHROMOSOME ABERRATION; DOWN SYNDROME; ELECTROPHYSIOLOGY; GENE EXPRESSION; GLUCOSE METABOLISM; HIPPOCAMPUS; HUMAN; LONG TERM POTENTIATION; MEMBRANE DEPOLARIZATION; MEMBRANE RESISTANCE; MEMBRANE STEADY POTENTIAL; MENTAL DEFICIENCY; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NEUROPATHOLOGY; NONHUMAN; PATHOGENESIS; PHENOTYPE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; REPOLARIZATION; REVIEW; SIGNAL TRANSDUCTION; SPINAL GANGLION; TRISOMY; TRISOMY 16; TRISOMY 21;

EID: 0035022091     PISSN: 01650173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0926-6410(00)00074-4     Document Type: Article

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