Differential degeneration of the locus coeruleus in dementia subtypes

Clinical Neuropathology

Volumn 30, Issue 3, 2011, Pages 104-110

  Brunnstrom H ^a   Friberg, N ^a   Lindberg, E ^a   Englund, E ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Alzheimer's disease; Frontotemporal lobar degeneration; Lewy body disease; Vascular dementia

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN DEGENERATION; BRAIN SLICE; CONTROLLED STUDY; DEMENTIA; DEPIGMENTATION; DIFFUSE LEWY BODY DISEASE; DISEASE SEVERITY; FEMALE; FRONTOTEMPORAL DEMENTIA; HUMAN; HUMAN TISSUE; LOCUS CERULEUS; LOCUS CERULEUS DEGENERATION; MAJOR CLINICAL STUDY; MALE; MULTIINFARCT DEMENTIA; PARKINSON DISEASE; PONS; PREDICTIVE VALUE; PRIORITY JOURNAL; SCORING SYSTEM; MIDDLE AGED; NERVE DEGENERATION; PATHOLOGY;

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; DEMENTIA; DEMENTIA, VASCULAR; FEMALE; HUMANS; LEWY BODY DISEASE; LOCUS COERULEUS; MALE; MIDDLE AGED; NERVE DEGENERATION; PARKINSON DISEASE;

EID: 79960121463     PISSN: 07225091     EISSN: None     Source Type: Journal    
DOI: 10.5414/NPP30104     Document Type: Article

References (28)

1. Gibbs ME, Summers RJ. Role of adrenoceptor subtypes in memory consolidation. Prog Neurobiol. 2002; 67: 345-391.
2. Berridge CW, Waterhouse BD. The locus coeruleusnoradrenergic system: modulation of behavioral state and state-dependent cognitive processes. Brain Res Rev. 2003; 42: 33-84.
3. Zweig RM, Cardillo JE, Cohen M, Giere S, Hedreen JC. The locus ceruleus and dementia in Parkinson's disease. Neurology. 1993; 43: 986-991.
4. Lyness SA, Zarow C, Chui HC. Neuron loss in key cholinergic and aminergic nuclei in Alzheimer disease: a meta-analysis. Neurobiol Aging. 2003; 24: 1-23.
5. Szot P, White SS, Greenup JL, Leverenz JB, Peskind ER, Raskind MA. Compensatory changes in the noradrenergic nervous system in the locus ceruleus and hippocampus of postmortem subjects with Alzheimer's disease and dementia with Lewy bodies. J Neurosci. 2006; 26: 467-478.
6. Haglund M, Sjöbeck M, Englund E. Locus ceruleus degeneration is ubiquitous in Alzheimer's disease: Possible implications for diagnosis and treatment. Neuropathology. 2006; 26: 528-532.
7. Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 1991; 82: 239-259.
8. Mirra SS, Heyman A, McKeel D, Sumi SM, Crain BJ, Brownlee LM, Vogel FS, Hughes JP, van Belle G, Berg L. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD): Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology. 1991; 41: 479-486.
9. Brun A. Vascular dementia: pathological findings. In: Burns A, Levy R (eds). Dementia. London: Chapman & Hall; 1994. p. 653-663.
10. Brun A, Englund E, Gustafson L, Passant U, Mann DMA, Neary D, Snowden JS; the Lund and Manchester Groups. Clinical and neuropathological criteria for frontotemporal dementia. J Neurol Neurosurg Psychiatry. 1994; 57: 416-418.
11. Wallin A, Brun A, Gustafson L, and the Swedish Consensus Group. Swedish consensus on dementia diseases. Acta Neurol Scand. 1994; 157: 1-31.
12. Braak H, Del Tredici K, Rüb U, de Vos RA, Jansen Steur EN, Braak E. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging. 2003; 24: 197-211.
13. McKeith IG, Dickson DW, Lowe J, Emre M, O'Brien JT, Feldman H, Cummings J, Duda JE, Lippa C, Perry EK, Aarsland D, Arai H, Ballard CG, Boeve B, Burn DJ, Costa D, Del Ser T, Dubois B, Galasko D, Gauthier S, Goetz CG, Gomez-Tortosa E, Halliday G, Hansen LA, Hardy J, Iwatsubo T, Kalaria RN, Kaufer D, Kenny RA, Korczyn A, Kosaka K, Lee VM, Lees A, Litvan I, Londos E, Lopez OL, Minoshima S, Mizuno Y, Molina JA, Mukaetova-Ladinska EB, Pasquier F, Perry RH, Schulz JB, Trojanowski JQ, Yamada M. Consortium on DLB. Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology. 2005; 65: 1863-1872.
14. Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL 3rd, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, Yokoo H, Murayama S, Woulfe J, Munoz DG, Dickson DW, Ince PG, Trojanowski JQ, Mann DM. Consortium for Frontotemporal Lobar Degeneration. Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathol. 2007; 114: 5-22.
15. Brunnström H, Englund E. Clinicopathological concordance in dementia diagnostics. Am J Geriatr Psychiatry. 2009; 17: 664-670.
16. Brun A, Englund E. Regional pattern of degeneration in Alzheimer's disease: neuronal loss and histopathological grading. Histopathology. 1981; 5: 549-564.
17. Brunnström H, Englund E. Comparison of four neuropathological scales for Alzheimer's disease. Clin Neuropathol. 2011; 30: 56-69.
18. Marcyniuk B, Mann DM, Yates PO. Loss of nerve cells from locus coeruleus in Alzheimer's disease is topographically arranged. Neurosci Lett. 1986; 64: 247-252.
19. Mountjoy CQ, BondareffW. Comparison of counts of neurons in the locus coeruleus made from serial sections and from a single section at the centre of the nucleus. Can J Neurol Sci. 1986; 13: 480-482.
20. Marcyniuk B, Mann DM, Yates PO. The topography of nerve cell loss from the locus caeruleus in elderly persons. Neurobiol Aging. 1989; 10: 5-9.
21. Bondareff W, Mountjoy CQ. Number of neurons in nucleus locus ceruleus in demented and non-demented patients: rapid estimation and correlated parameters. Neurobiol Aging. 1986; 7: 297-300.
22. Zarow C, Lyness SA, Mortimer JA, Chui HC. Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases. Arch Neurol. 2003; 60: 337-341.
23. Stefanova N, Bücke P, Duerr S, Wenning GK. Multiple system atrophy: an update. Lancet Neurol. 2009; 8: 1172-1178.
24. Wszolek ZK, Slowinski J, Golan M, Dickson DW. Frontotemporal dementia and parkinsonism linked to chromosome 17. Folia Neuropathol. 2005; 43: 258-270.
25. Ince PG, Clark B, Holton J, Revesz T, Wharton SB. Diseases of movement and system degenerations. In: Love S, Louis DN, Ellison DW (eds). Greenfield's neuropathology, 8th edition. London: Hodder Arnold; 2008. p. 889-1030.
26. Grudzien A, Shaw P, Weintraub S, Bigio E, Mash DC, Mesulam MM. Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease. Neurobiol Aging. 2007; 28: 327-335.
27. Modrego PJ. Depression in Alzheimer's disease. Pathophysiology, diagnosis, and treatment. J Alzheimers Dis. 2010 [Epub ahead of print].
28. Rosenberg PB, Drye LT, Martin BK, Frangakis C, Mintzer JE, Weintraub D, Porsteinsson AP, Schneider LS, Rabins PV, Munro CA, Meinert CL, Lyketsos CG; DIADS-2 Research Group. Sertraline for the treatment of depression in Alzheimer disease. Am J Geriatr Psychiatry. 2010; 18: 136-145.