Down syndrome fibroblast model of Alzheimer-related endosome pathology: Accelerated endocytosis promotes late endocytic defects

American Journal of Pathology

Volumn 173, Issue 2, 2008, Pages 370-384

  Cataldo, Anne M ^a,b   Mathews, Paul M ^c,d   Boiteau, Anne Boyer ^a   Hassinger, Linda C ^a   Peterhoff, Corrinne M ^c   Jiang, Ying ^c   Mullaney, Kerry ^c   Neve, Rachael L ^a,b   Gruenberg, Jean ^e   Nixon, Ralph A ^c,d  

^a MCLEAN HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; HYDROLASE; PHOSPHATIDIC ACID; RAB7 PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CELL COMPARTMENTALIZATION; CELL FUSION; CELL MIGRATION; CELL VACUOLE; CONTROLLED STUDY; DOWN SYNDROME; ENDOCYTOSIS; ENDOSOME; FIBROBLAST; HUMAN; HUMAN TISSUE; NERVE CELL; PATHOGENESIS; PRIORITY JOURNAL; RECYCLING;

EID: 48249095748     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2008.071053     Document Type: Article

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