메뉴 건너뛰기




Volumn 114, Issue 4, 2012, Pages 375-388

Virgin olive oil in preventive medicine: From legend to epigenetics

Author keywords

Extra virgin olive oil; Human health; Physiological mechanisms; Therapeutic

Indexed keywords


EID: 84859624125     PISSN: 14387697     EISSN: 14389312     Source Type: Journal    
DOI: 10.1002/ejlt.201100164     Document Type: Review
Times cited : (71)

References (120)
  • 1
    • 77958048484 scopus 로고    scopus 로고
    • Flandrin, J., Montanari, M. (Eds.), Laterza, Roma-Bari (Italy)
    • Sorcinelli, P., in: Flandrin, J., Montanari, M. (Eds.), Storia Dell'alimentazione, Laterza, Roma-Bari (Italy) 1997, pp. 632- 642.
    • (1997) Storia Dell'alimentazione , pp. 632-642
    • Sorcinelli, P.1
  • 2
    • 0033641002 scopus 로고    scopus 로고
    • L'uso dell'olio d'oliva nella medicina del mondo antico
    • Mazzini, I., L'uso dell'olio d'oliva nella medicina del mondo antico. Medizinhist. J. 2000, 35, 105- 126.
    • (2000) Medizinhist. J. , vol.35 , pp. 105-126
    • Mazzini, I.1
  • 3
    • 77958073817 scopus 로고    scopus 로고
    • Flandrin, J., Montanari, M. (Eds.), Laterza, Roma-Bari (Italy).
    • Mazzini, I., in: Flandrin, J., Montanari, M. (Eds.), Storia Dell'alimentazione, Laterza, Roma-Bari (Italy) 1997, pp. 191- 200.
    • (1997) Storia Dell'alimentazione , pp. 191-200
    • Mazzini, I.1
  • 6
    • 0028838042 scopus 로고
    • Dietary protein, cholesterol and atherosclerosis: A review of the early history
    • Kritchevsky, D., Dietary protein, cholesterol and atherosclerosis: A review of the early history. J. Utr. 1995, 125, 589- 593.
    • (1995) J. Utr. , vol.125 , pp. 589-593
    • Kritchevsky, D.1
  • 7
    • 0013951835 scopus 로고
    • Serum-cholesterol response to changes in dietary lipids
    • Keys, A., Parlin, R. W., Serum-cholesterol response to changes in dietary lipids. Am. J. Clin. Nutr. 1966, 19, 175- 181.
    • (1966) Am. J. Clin. Nutr. , vol.19 , pp. 175-181
    • Keys, A.1    Parlin, R.W.2
  • 8
    • 0014770327 scopus 로고
    • Coronary heart disease in seven countries. VII. Five-year experience in rural Italy
    • Fidanza, F., Puddu, V., Imbimbo, A. B., Menotti, A., Keys, A., Coronary heart disease in seven countries. VII. Five-year experience in rural Italy. Circulation 1970, 41, 63- 75.
    • (1970) Circulation , vol.41 , pp. 63-75
    • Fidanza, F.1    Puddu, V.2    Imbimbo, A.B.3    Menotti, A.4    Keys, A.5
  • 9
    • 0021164827 scopus 로고
    • The seven countries study: 2,289 deaths in 15 years
    • Keys, A., Menotti, A., Aravanis, C., Blackburn, H. et al., The seven countries study: 2, 289 deaths in 15 years. Prev. Med. 1984, 13, 141- 154.
    • (1984) Prev. Med. , vol.13 , pp. 141-154
    • Keys, A.1    Menotti, A.2    Aravanis, C.3    Blackburn, H.4
  • 10
    • 0021833710 scopus 로고
    • Serum cholesterol and cancer mortality in the Seven Countries Study
    • Keys, A., Aravanis, C., Blackburn, H., Buzina, R. et al., Serum cholesterol and cancer mortality in the Seven Countries Study. Am. J. Epidemiol. 1985, 121, 870- 883.
    • (1985) Am. J. Epidemiol. , vol.121 , pp. 870-883
    • Keys, A.1    Aravanis, C.2    Blackburn, H.3    Buzina, R.4
  • 11
    • 0022982012 scopus 로고
    • The diet and 15-year death rate in the Seven Countries Study
    • Keys, A., Menotti, A., Karvonen, M. J., Aravanis, C. et al., The diet and 15-year death rate in the Seven Countries Study. Am. J. Epidemiol. 1986, 124, 903- 915.
    • (1986) Am. J. Epidemiol. , vol.124 , pp. 903-915
    • Keys, A.1    Menotti, A.2    Karvonen, M.J.3    Aravanis, C.4
  • 12
    • 0024352356 scopus 로고
    • Seven Countries Study. First 20-year mortality data in 12 cohorts of six countries
    • Menotti, A., Keys, A., Aravanis, C., Blackburn, H. et al., Seven Countries Study. First 20-year mortality data in 12 cohorts of six countries. Ann. Med. 1989, 21, 175- 179.
    • (1989) Ann. Med. , vol.21 , pp. 175-179
    • Menotti, A.1    Keys, A.2    Aravanis, C.3    Blackburn, H.4
  • 13
    • 0029050073 scopus 로고
    • Cretan Mediterranean diet for prevention of coronary heart Disease
    • Renaud, S., de Lorgeril, M., Delaye, J., Cretan Mediterranean diet for prevention of coronary heart Disease. Am. J. Clin. Nutr. 1995, 61, 1360- 1367.
    • (1995) Am. J. Clin. Nutr. , vol.61 , pp. 1360-1367
    • Renaud, S.1    de Lorgeril, M.2    Delaye, J.3
  • 14
    • 0038310626 scopus 로고    scopus 로고
    • Adherence to a Mediterranean diet and survival in a Greek population
    • Trichopoulou, A., Costacou, T., Bamia, C., Trichopoulos, D., Adherence to a Mediterranean diet and survival in a Greek population. N. Engl. J. Med. 2003, 348, 2599- 2608.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 2599-2608
    • Trichopoulou, A.1    Costacou, T.2    Bamia, C.3    Trichopoulos, D.4
  • 15
    • 17644420338 scopus 로고    scopus 로고
    • Mediterranean diet and survival among patients with coronary heart disease in Greece
    • Trichopoulou, A., Bamia, C., Trichopoulos, D., Mediterranean diet and survival among patients with coronary heart disease in Greece. Arch. Intern. Med. 2005, 165, 929- 935.
    • (2005) Arch. Intern. Med. , vol.165 , pp. 929-935
    • Trichopoulou, A.1    Bamia, C.2    Trichopoulos, D.3
  • 17
    • 33646848795 scopus 로고    scopus 로고
    • The Mediterranean diet: Science and practice
    • Willett, W. C., The Mediterranean diet: Science and practice. Public Health Nutr. 2006, 9, 105- 110.
    • (2006) Public Health Nutr. , vol.9 , pp. 105-110
    • Willett, W.C.1
  • 18
    • 34248530383 scopus 로고    scopus 로고
    • Long-term adoption of a Mediterranean diet is associated with a better health status in elderly people; a cross-sectional survey in Cyprus
    • Panagiotakos, D. B., Polystipioti, A., Papairakleous, N., Polychronopoulos, E., Long-term adoption of a Mediterranean diet is associated with a better health status in elderly people; a cross-sectional survey in Cyprus. Asia Pac. J. Clin. Nutr. 2007, 16, 331- 337.
    • (2007) Asia Pac. J. Clin. Nutr. , vol.16 , pp. 331-337
    • Panagiotakos, D.B.1    Polystipioti, A.2    Papairakleous, N.3    Polychronopoulos, E.4
  • 19
    • 52649094446 scopus 로고    scopus 로고
    • Adherence to Mediterranean diet and health status: Meta-analysis
    • Sofi, F., Cesari, F., Abbate, R., Gensini, G. F. et al., Adherence to Mediterranean diet and health status: Meta-analysis. Br. Med. J. 2008, 337, a1344.
    • (2008) Br. Med. J. , vol.337
    • Sofi, F.1    Cesari, F.2    Abbate, R.3    Gensini, G.F.4
  • 20
    • 58149398550 scopus 로고    scopus 로고
    • Adherence to a Mediterranean-type diet and reduced prevalence of clustered cardiovascular risk factors in a cohort of 3,204 high-risk patients
    • Sánchez-Taínta, A., Estruch, R., Bulló, M., Gómez-Gracia, E. et al., Adherence to a Mediterranean-type diet and reduced prevalence of clustered cardiovascular risk factors in a cohort of 3, 204 high-risk patients. Eur. J. Cardiov. Prev. R 2008, 15, 589- 593.
    • (2008) Eur. J. Cardiov. Prev. R , vol.15 , pp. 589-593
    • Sánchez-Taínta, A.1    Estruch, R.2    Bulló, M.3    Gómez-Gracia, E.4
  • 21
    • 0031004377 scopus 로고    scopus 로고
    • Heart disease risk-factor status and dietary changes in the Cretan population over the past 30 years: The Seven Countries Study
    • Kafatos, A., Diacatou, A., Voukiklaris, G., Heart disease risk-factor status and dietary changes in the Cretan population over the past 30 years: The Seven Countries Study. Am. J. Clin. Nutr. 1997, 65, 1882- 1886.
    • (1997) Am. J. Clin. Nutr. , vol.65 , pp. 1882-1886
    • Kafatos, A.1    Diacatou, A.2    Voukiklaris, G.3
  • 22
    • 0028235692 scopus 로고
    • Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease
    • de Lorgeril, M., Renaud, S., Mamelle, N., Salen, P. et al., Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease. Lancet 1994, 343, 1454- 1459.
    • (1994) Lancet , vol.343 , pp. 1454-1459
    • de Lorgeril, M.1    Renaud, S.2    Mamelle, N.3    Salen, P.4
  • 23
    • 0032955055 scopus 로고    scopus 로고
    • Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: Final report of the Lyon Diet Heart Study
    • de Lorgeril, M., Salen, P., Martin, J. L., Monjaud, I. et al., Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: Final report of the Lyon Diet Heart Study. Circulation 1999, 99, 779- 785.
    • (1999) Circulation , vol.99 , pp. 779-785
    • de Lorgeril, M.1    Salen, P.2    Martin, J.L.3    Monjaud, I.4
  • 24
    • 24644503719 scopus 로고    scopus 로고
    • Genomic analysis of the response of mouse models to high-fat feeding shows a major role of nuclear receptors in the simultaneous regulation of lipid and inflammatory genes
    • Kreeft, A. J., Moen, C. J., Porter, G., Kasanmoentalib, S. et al., Genomic analysis of the response of mouse models to high-fat feeding shows a major role of nuclear receptors in the simultaneous regulation of lipid and inflammatory genes. Atherosclerosis 2005, 182, 249- 257.
    • (2005) Atherosclerosis , vol.182 , pp. 249-257
    • Kreeft, A.J.1    Moen, C.J.2    Porter, G.3    Kasanmoentalib, S.4
  • 26
    • 0038135048 scopus 로고    scopus 로고
    • Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins:a meta-analysis of 60 controlled trials
    • Mensink, R. P., Zock, P. L., Kester, A. D., Katan, M. B., Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins:a meta-analysis of 60 controlled trials. Am. J. Clin. Nutr. 2003, 77, 1146- 1155.
    • (2003) Am. J. Clin. Nutr. , vol.77 , pp. 1146-1155
    • Mensink, R.P.1    Zock, P.L.2    Kester, A.D.3    Katan, M.B.4
  • 27
    • 84859603716 scopus 로고    scopus 로고
    • I composti a struttura fenolica, componenti minoritari esclusivi dell'olio extravergine di oliva e il loro ruolo salutistico. in: proceedings of the XXI Congresso Nazionale SIPPS, Siena
    • Cerretani, L., Bendini, A., Lercker, G., Caramia, G., I composti a struttura fenolica, componenti minoritari esclusivi dell'olio extravergine di oliva e il loro ruolo salutistico. in: proceedings of the XXI Congresso Nazionale SIPPS, Siena, 2009, pp. 102- 103.
    • (2009) , pp. 102-103
    • Cerretani, L.1    Bendini, A.2    Lercker, G.3    Caramia, G.4
  • 28
    • 21344445712 scopus 로고    scopus 로고
    • Trentalance. 3-Hydroxy-3-methylglutaryl coenzyme A reductase deregulation and age-related hypercholesterolemia: A new role for ROS
    • Pallottini, V., Martini, C., Pascolini, A., Cavallini, G. et al., Trentalance. 3-Hydroxy-3-methylglutaryl coenzyme A reductase deregulation and age-related hypercholesterolemia: A new role for ROS. Mech. Ageing Dev. 2005, 126, 845- 851.
    • (2005) Mech. Ageing Dev. , vol.126 , pp. 845-851
    • Pallottini, V.1    Martini, C.2    Pascolini, A.3    Cavallini, G.4
  • 29
    • 33744991758 scopus 로고    scopus 로고
    • The role of virgin olive oil components in the modulation of endothelial function
    • Perona, J. S., Cabello-Moruno, R., Ruiz-Gutierrez, V., The role of virgin olive oil components in the modulation of endothelial function. J. Nutr. Biochem. 2006, 17, 429- 445.
    • (2006) J. Nutr. Biochem. , vol.17 , pp. 429-445
    • Perona, J.S.1    Cabello-Moruno, R.2    Ruiz-Gutierrez, V.3
  • 30
    • 34548444575 scopus 로고    scopus 로고
    • Phenolic molecules in virgin olive oils: A survey of their sensory properties, health effects, antioxidant activity and analytical methods. An overview of the last decade
    • Bendini, A., Cerretani, L., Carrasco-Pancorbo, A., Gómez-Caravaca, A. M. et al., Phenolic molecules in virgin olive oils: A survey of their sensory properties, health effects, antioxidant activity and analytical methods. An overview of the last decade. Molecules 2007, 12, 1679- 1719.
    • (2007) Molecules , vol.12 , pp. 1679-1719
    • Bendini, A.1    Cerretani, L.2    Carrasco-Pancorbo, A.3    Gómez-Caravaca, A.M.4
  • 31
    • 0030471905 scopus 로고    scopus 로고
    • Plasma lipids, erythrocyte membrane lipids and blood pressure of hypertensive women after ingestion of dietary oleic acid from two different sources
    • Ruiz-Gutiérrez, V., Muriana, F. J., Guerrero, A., Cert, A. M., Villar, J., Plasma lipids, erythrocyte membrane lipids and blood pressure of hypertensive women after ingestion of dietary oleic acid from two different sources. J. Hypertens. 1996, 14, 1483- 1490.
    • (1996) J. Hypertens. , vol.14 , pp. 1483-1490
    • Ruiz-Gutiérrez, V.1    Muriana, F.J.2    Guerrero, A.3    Cert, A.M.4    Villar, J.5
  • 32
  • 33
    • 4544288392 scopus 로고    scopus 로고
    • Effect of a mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: A randomized trial
    • Esposito, K., Marfella, R., Ciotola, M., Di Palo, C. et al., Effect of a mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: A randomized trial. JAMA 2004, 292, 1440- 1446.
    • (2004) JAMA , vol.292 , pp. 1440-1446
    • Esposito, K.1    Marfella, R.2    Ciotola, M.3    Di Palo, C.4
  • 34
    • 5144222880 scopus 로고    scopus 로고
    • Olive oil, the Mediterranean diet, and arterial blood pressure: The Greek European Prospective Investigation into Cancer and Nutrition (EPIC) study
    • Psaltopoulou, T., Naska, A., Orfanos, P., Trichopoulos, D. et al., Olive oil, the Mediterranean diet, and arterial blood pressure: The Greek European Prospective Investigation into Cancer and Nutrition (EPIC) study. Am. J. Clin. Nutr. 2004, 80, 1012- 1018.
    • (2004) Am. J. Clin. Nutr. , vol.80 , pp. 1012-1018
    • Psaltopoulou, T.1    Naska, A.2    Orfanos, P.3    Trichopoulos, D.4
  • 36
    • 38149071017 scopus 로고    scopus 로고
    • Acute combined effects of olive oil and wine on pressure wave reflections: Another beneficial influence of the Mediterranean diet antioxidants
    • Papamichael, C. M., Karatzi, K. N., Papaioannou, T. G., Karatzis, E. N. et al., Acute combined effects of olive oil and wine on pressure wave reflections: Another beneficial influence of the Mediterranean diet antioxidants? J. Hypertens. 2008, 26, 223- 229.
    • (2008) J. Hypertens. , vol.26 , pp. 223-229
    • Papamichael, C.M.1    Karatzi, K.N.2    Papaioannou, T.G.3    Karatzis, E.N.4
  • 37
    • 27644472713 scopus 로고    scopus 로고
    • Phenolic content of virgin olive oil improves ischemic reactive hyperemia in hypercholesterolemic patients
    • Ruano, J., Miranda, J. L., Fuentes, F., Moreno, J. A. et al., Phenolic content of virgin olive oil improves ischemic reactive hyperemia in hypercholesterolemic patients. J. Am. Coll. Cardiol. 2005, 46, 1864- 1868.
    • (2005) J. Am. Coll. Cardiol. , vol.46 , pp. 1864-1868
    • Ruano, J.1    Miranda, J.L.2    Fuentes, F.3    Moreno, J.A.4
  • 38
    • 20444389800 scopus 로고    scopus 로고
    • Antioxidant effect of virgin olive oil in patients with stable coronary heart disease: A randomized, crossover, controlled, clinical trial
    • Fitó, M., Cladellas, M., de la Torre, R., Martí, J. et al., Antioxidant effect of virgin olive oil in patients with stable coronary heart disease: A randomized, crossover, controlled, clinical trial. Atherosclerosis 2005, 181, 149- 158.
    • (2005) Atherosclerosis , vol.181 , pp. 149-158
    • Fitó, M.1    Cladellas, M.2    de la Torre, R.3    Martí, J.4
  • 39
    • 33646474254 scopus 로고    scopus 로고
    • Monounsaturated fatty acids, olive oil and blood pressure: Epidemiological, clinical and experimental evidence
    • Alonso, A., Ruiz-Gutierrez, V., Martínez-González, M. A., Monounsaturated fatty acids, olive oil and blood pressure: Epidemiological, clinical and experimental evidence. Public Health Nutr. 2006, 9, 251- 257.
    • (2006) Public Health Nutr. , vol.9 , pp. 251-257
    • Alonso, A.1    Ruiz-Gutierrez, V.2    Martínez-González, M.A.3
  • 40
    • 33845420450 scopus 로고    scopus 로고
    • Postprandial anti-inflammatory and antioxidant effects of extra virgin olive oil
    • Bogani, P., Galli, C., Villa, M., Visioli, F., Postprandial anti-inflammatory and antioxidant effects of extra virgin olive oil. Atherosclerosis 2007, 190, 181- 186.
    • (2007) Atherosclerosis , vol.190 , pp. 181-186
    • Bogani, P.1    Galli, C.2    Villa, M.3    Visioli, F.4
  • 41
    • 41749098830 scopus 로고    scopus 로고
    • 2-Hydroxyoleic acid affects cardiomyocyte [Ca2+]i transient and contractility in a region-dependent manner
    • Borchert, G. H., Giggey, M., Kolar, F., Wong, T. M. et al., 2-Hydroxyoleic acid affects cardiomyocyte [Ca2+]i transient and contractility in a region-dependent manner. Am. J. Physiol. Heart Circ. Physiol. 2008, 294, 1948- 1955.
    • (2008) Am. J. Physiol. Heart Circ. Physiol. , vol.294 , pp. 1948-1955
    • Borchert, G.H.1    Giggey, M.2    Kolar, F.3    Wong, T.M.4
  • 42
    • 34047246885 scopus 로고    scopus 로고
    • Adherence to the Mediterranean food pattern predicts the prevalence of hypertension, hypercholesterolemia, diabetes and obesity, among healthy adults; the accuracy of the MedDietScore
    • Panagiotakos, D. B., Pitsavos, C., Arvaniti, F., Stefanadis, C., Adherence to the Mediterranean food pattern predicts the prevalence of hypertension, hypercholesterolemia, diabetes and obesity, among healthy adults; the accuracy of the MedDietScore. Prev. Med. 2007, 44, 335- 340.
    • (2007) Prev. Med. , vol.44 , pp. 335-340
    • Panagiotakos, D.B.1    Pitsavos, C.2    Arvaniti, F.3    Stefanadis, C.4
  • 43
    • 58849150007 scopus 로고    scopus 로고
    • Inclusion of dietary evaluation in cardiovascular disease risk prediction models. increases accuracy and reduces bias of the estimations
    • Panagiotakos, D. B., Pitsavos, C., Stefanadis, C., Inclusion of dietary evaluation in cardiovascular disease risk prediction models. increases accuracy and reduces bias of the estimations. Risk Anal. 2009, 29, 176- 186.
    • (2009) Risk Anal. , vol.29 , pp. 176-186
    • Panagiotakos, D.B.1    Pitsavos, C.2    Stefanadis, C.3
  • 44
    • 15244356936 scopus 로고    scopus 로고
    • Virgin Olive Oil Study (VOLOS): Vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patients
    • Visioli, F., Caruso, D., Grande, S., Bosisio, R. et al., Virgin Olive Oil Study (VOLOS): Vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patients. Eur. J. Nutr. 2005, 44, 121- 127.
    • (2005) Eur. J. Nutr. , vol.44 , pp. 121-127
    • Visioli, F.1    Caruso, D.2    Grande, S.3    Bosisio, R.4
  • 45
    • 0036988766 scopus 로고    scopus 로고
    • Effect of extra virgin olive oil on experimental thrombosis and primary haemostasis in rats
    • Brzosko, S., De Curtis, A., Murzilli, S., de Gaetano, G. et al., Effect of extra virgin olive oil on experimental thrombosis and primary haemostasis in rats. Nutr. Metab. Cardiovasc. Dis. 2002, 12, 337- 342.
    • (2002) Nutr. Metab. Cardiovasc. Dis. , vol.12 , pp. 337-342
    • Brzosko, S.1    De Curtis, A.2    Murzilli, S.3    de Gaetano, G.4
  • 46
    • 2942530422 scopus 로고    scopus 로고
    • Oxidative stress activates the plasminogen activator inhibitor type 1 (PAI-1) promoter through an AP-1 response element and cooperates with insulin for additive effects on PAI-1 transcription
    • Vulin, A. I., Stanley, F. M., Oxidative stress activates the plasminogen activator inhibitor type 1 (PAI-1) promoter through an AP-1 response element and cooperates with insulin for additive effects on PAI-1 transcription. J. Biol. Chem. 2004, 279, 25172- 25178.
    • (2004) J. Biol. Chem. , vol.279 , pp. 25172-25178
    • Vulin, A.I.1    Stanley, F.M.2
  • 47
    • 39049184502 scopus 로고    scopus 로고
    • Antioxidants in the Mediterranean diets: An update
    • Bogani, P., Visioli, F., Antioxidants in the Mediterranean diets: An update. World Rev. Nutr. Diet 2007, 97, 162- 169.
    • (2007) World Rev. Nutr. Diet , vol.97 , pp. 162-169
    • Bogani, P.1    Visioli, F.2
  • 49
    • 38949205636 scopus 로고    scopus 로고
    • Chronic dietary fat intake modifies the postprandial response of hemostatic markers to a single fatty test meal
    • Delgado-Lista, J., Lopez-Miranda, J., Cortés, B., Perez-Martinez, P. et al., Chronic dietary fat intake modifies the postprandial response of hemostatic markers to a single fatty test meal. Am. J. Clin. Nutr. 2008, 87, 317- 322.
    • (2008) Am. J. Clin. Nutr. , vol.87 , pp. 317-322
    • Delgado-Lista, J.1    Lopez-Miranda, J.2    Cortés, B.3    Perez-Martinez, P.4
  • 50
    • 19144371367 scopus 로고    scopus 로고
    • A thromboxane effect of a hydroxytyrosol-rich olive oil wastewater extract in patients with uncomplicated type I diabetes
    • Léger, C. L., Carbonneau, M. A., Michel, F., Mas, E. et al., A thromboxane effect of a hydroxytyrosol-rich olive oil wastewater extract in patients with uncomplicated type I diabetes. Eur. J. Clin. Nutr. 2005, 59, 727- 730.
    • (2005) Eur. J. Clin. Nutr. , vol.59 , pp. 727-730
    • Léger, C.L.1    Carbonneau, M.A.2    Michel, F.3    Mas, E.4
  • 51
    • 0033945291 scopus 로고    scopus 로고
    • Phenolic compounds and squalene in olive oils: The concentration and antioxidant potential of total phenols, simple phenols, secoroids, lignans and squalene
    • Owen, R. W., Mier, W., Giacosa, A., Hull, W. E. et al., Phenolic compounds and squalene in olive oils: The concentration and antioxidant potential of total phenols, simple phenols, secoroids, lignans and squalene. Food Chem. Toxicol. 2000, 38, 647- 659.
    • (2000) Food Chem. Toxicol. , vol.38 , pp. 647-659
    • Owen, R.W.1    Mier, W.2    Giacosa, A.3    Hull, W.E.4
  • 53
    • 45549096874 scopus 로고    scopus 로고
    • Gli acidi grassi essenziali omega-6 e omega-3: Dalla loro scoperta al loro impiego in terapia
    • Caramia, G., Gli acidi grassi essenziali omega-6 e omega-3: Dalla loro scoperta al loro impiego in terapia. Minerva Pediatr. 2008, 60, 219- 233.
    • (2008) Minerva Pediatr. , vol.60 , pp. 219-233
    • Caramia, G.1
  • 54
    • 47249149700 scopus 로고    scopus 로고
    • Omega-3: Dall'olio di fegato di merluzzo alla nutrigenomica
    • Caramia, G., Omega-3: Dall'olio di fegato di merluzzo alla nutrigenomica. Minerva Pediatr. 2008, 60, 443- 455.
    • (2008) Minerva Pediatr. , vol.60 , pp. 443-455
    • Caramia, G.1
  • 55
    • 84889724680 scopus 로고    scopus 로고
    • Industrie Agrarie e Agroalimentari, Hoepli (Ed.), 4° edizione, Milano (Italy).
    • Sicheri, G., In: Industrie Agrarie e Agroalimentari, Hoepli (Ed.), 4° edizione, Milano (Italy) 2002, pp. 544- 552.
    • (2002) , pp. 544-552
    • Sicheri, G.1
  • 56
    • 0033549116 scopus 로고    scopus 로고
    • High monounsaturated fatty acids intake protects against age-related cognitive decline
    • Solfrizzi, V., Panza, F., Torres, F., Mastroianni, F. et al., High monounsaturated fatty acids intake protects against age-related cognitive decline. Neurology 1999, 52, 1524- 1530.
    • (1999) Neurology , vol.52 , pp. 1524-1530
    • Solfrizzi, V.1    Panza, F.2    Torres, F.3    Mastroianni, F.4
  • 57
    • 85071240816 scopus 로고    scopus 로고
    • Scientific Opinion on the substantiation of health claims related to polyphenols in olive and protection of LDL particles from oxidative damage
    • (ID 1333, 1638, 1639, 1696, 2865), maintenance of normal blood HDL-cholesterol concentrations (ID 1639), maintenance of normal blood pressure (ID 3781), "anti-inflammatory properties" (ID 1882), "contributes to the upper respiratory tract health" (ID 3468), "can help to maintain a normal function of gastrointestinal tract" (3779), and "contributes to body defences against external agents" (ID 3467) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
    • Agostoni, C., Bresson, J. L., Fairweather-Tait, S., Flynn, A. et al., Scientific Opinion on the substantiation of health claims related to polyphenols in olive and protection of LDL particles from oxidative damage (ID 1333, 1638, 1639, 1696, 2865), maintenance of normal blood HDL-cholesterol concentrations (ID 1639), maintenance of normal blood pressure (ID 3781), "anti-inflammatory properties" (ID 1882), "contributes to the upper respiratory tract health" (ID 3468), "can help to maintain a normal function of gastrointestinal tract" (3779), and "contributes to body defences against external agents" (ID 3467) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 EFSA J. 2011, 9, 2033.
    • (2011) EFSA J. , vol.9 , pp. 2033
    • Agostoni, C.1    Bresson, J.L.2    Fairweather-Tait, S.3    Flynn, A.4
  • 58
    • 0037387575 scopus 로고    scopus 로고
    • Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: Antiatherogenic properties of Mediterranean diet phytochemicals
    • Carluccio, M. A., Siculella, L., Ancora, M. A., Massaro, M. et al., Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: Antiatherogenic properties of Mediterranean diet phytochemicals. Arterioscler. Thromb. Vasc. Biol. 2003, 23, 622- 629.
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , pp. 622-629
    • Carluccio, M.A.1    Siculella, L.2    Ancora, M.A.3    Massaro, M.4
  • 60
    • 34250342984 scopus 로고    scopus 로고
    • Effect of a traditional Mediterranean diet on lipoprotein oxidation: A randomized controlled trial
    • Fitó, M., Guxens, M., Corella, D., Sáez, G. et al., Effect of a traditional Mediterranean diet on lipoprotein oxidation: A randomized controlled trial. Arch. Intern. Med. 2007, 167, 1195- 1203.
    • (2007) Arch. Intern. Med. , vol.167 , pp. 1195-1203
    • Fitó, M.1    Guxens, M.2    Corella, D.3    Sáez, G.4
  • 62
    • 49649092062 scopus 로고    scopus 로고
    • Relations between metabolic syndrome, oxidative stress and inflammation and cardiovascular disease
    • Holvoet, P., Relations between metabolic syndrome, oxidative stress and inflammation and cardiovascular disease. Verh. K Acad. Geneeskd. Belg. 2008, 70, 193- 219.
    • (2008) Verh. K Acad. Geneeskd. Belg. , vol.70 , pp. 193-219
    • Holvoet, P.1
  • 63
    • 0028986372 scopus 로고
    • The effect of alpha-tocopherol supplementation on LDL oxidation. A dose-response study
    • Jialal, I., Fuller, C. J., Huet, B. A., The effect of alpha-tocopherol supplementation on LDL oxidation. A dose-response study. Arterioscler. Thromb. Vasc. Biol. 1995, 15, 190.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 190
    • Jialal, I.1    Fuller, C.J.2    Huet, B.A.3
  • 64
    • 0026645528 scopus 로고
    • Supplementation with vitamin E but not beta-carotene in vivo protects low density lipoprotein from lipid peroxidation in vitro. Effect of cigarette smoking
    • Princen, H. M., van Poppel, G., Vogelezang, C., Buytenhek, R., Kok, F. J., Supplementation with vitamin E but not beta-carotene in vivo protects low density lipoprotein from lipid peroxidation in vitro. Effect of cigarette smoking. Arterioscler. Thromb. 1992, 12, 554- 562.
    • (1992) Arterioscler. Thromb. , vol.12 , pp. 554-562
    • Princen, H.M.1    van Poppel, G.2    Vogelezang, C.3    Buytenhek, R.4    Kok, F.J.5
  • 65
    • 77954366508 scopus 로고    scopus 로고
    • Diet and cancer today: An update
    • Mazzanti, R., Diet and cancer today: An update. Nutr. Ther. Metabol 2010, 28, 25- 32.
    • (2010) Nutr. Ther. Metabol , vol.28 , pp. 25-32
    • Mazzanti, R.1
  • 66
    • 56349099145 scopus 로고    scopus 로고
    • Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway
    • Reyes-Zurita, F. J., Rufino-Palomares, E. E., Lupiánez, J. A., Cascante, M., Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway. Cancer Lett. 2009, 273, 44- 54.
    • (2009) Cancer Lett. , vol.273 , pp. 44-54
    • Reyes-Zurita, F.J.1    Rufino-Palomares, E.E.2    Lupiánez, J.A.3    Cascante, M.4
  • 67
    • 77953887979 scopus 로고    scopus 로고
    • Mediatori lipidici, infezioni e infiammazioni: Evoluzione delle conoscenze e prospettive terapeutiche
    • Caramia, G., Fanos, V., Mediatori lipidici, infezioni e infiammazioni: Evoluzione delle conoscenze e prospettive terapeutiche. Giorn. It. Inf. Ped. 2007, 9, 15- 27.
    • (2007) Giorn. It. Inf. Ped. , vol.9 , pp. 15-27
    • Caramia, G.1    Fanos, V.2
  • 68
    • 24344452961 scopus 로고    scopus 로고
    • Phytochemistry: Ibuprofen-like activity in extra-virgin olive oil
    • Beauchamp, G. K., Keast, R. S., Morel, D., Lin, J. et al., Phytochemistry: Ibuprofen-like activity in extra-virgin olive oil. Nature 2005, 437, 45- 46.
    • (2005) Nature , vol.437 , pp. 45-46
    • Beauchamp, G.K.1    Keast, R.S.2    Morel, D.3    Lin, J.4
  • 69
    • 0036849837 scopus 로고    scopus 로고
    • Major phenolic compounds in olive oil: Metabolism and health effects
    • Tuck, K. L., Hayball, P. J., Major phenolic compounds in olive oil: Metabolism and health effects. J. Nutr. Biochem. 2002, 13, 636- 644.
    • (2002) J. Nutr. Biochem. , vol.13 , pp. 636-644
    • Tuck, K.L.1    Hayball, P.J.2
  • 71
    • 0036927418 scopus 로고    scopus 로고
    • Update on aspirin in the treatment and prevention of cardiovascular disease
    • Hennekens, C. H., Update on aspirin in the treatment and prevention of cardiovascular disease. Am. J. Manag. Care 2002, 8, 691- 700.
    • (2002) Am. J. Manag. Care , vol.8 , pp. 691-700
    • Hennekens, C.H.1
  • 72
    • 0021162822 scopus 로고
    • Pathophysiological mechanisms of sudden death induced by platelet activating factor
    • Lefer, A. M., Müller, H. F., Smith, J. B., Pathophysiological mechanisms of sudden death induced by platelet activating factor. J. Pharmacol. 1984, 83, 125- 130.
    • (1984) J. Pharmacol. , vol.83 , pp. 125-130
    • Lefer, A.M.1    Müller, H.F.2    Smith, J.B.3
  • 73
    • 38149012198 scopus 로고    scopus 로고
    • Population pharmacodynamic modelling of aspirin- and Ibuprofen-induced inhibition of platelet aggregation in healthy subjects
    • Hong, Y., Gengo, F. M., Rainka, M. M., Bates, V. E., Mager, D. E., Population pharmacodynamic modelling of aspirin- and Ibuprofen-induced inhibition of platelet aggregation in healthy subjects. Clin. Pharmacokinet. 2008, 47, 129- 137.
    • (2008) Clin. Pharmacokinet. , vol.47 , pp. 129-137
    • Hong, Y.1    Gengo, F.M.2    Rainka, M.M.3    Bates, V.E.4    Mager, D.E.5
  • 74
    • 51349119554 scopus 로고    scopus 로고
    • Similar reductions in the risk of human colon cancer by selective and nonselective cyclooxygenase-2 (COX-2) inhibitors
    • Harris, R. E., Beebe-Donk, J., Alshafie, G. A., Similar reductions in the risk of human colon cancer by selective and nonselective cyclooxygenase-2 (COX-2) inhibitors. BMC Cancer 2008, 8, 237.
    • (2008) BMC Cancer , vol.8 , pp. 237
    • Harris, R.E.1    Beebe-Donk, J.2    Alshafie, G.A.3
  • 75
    • 0242414463 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs can lower amyloidogenic Abeta42 by inhibiting Rho
    • Zhou, Y., Su, Y., Li, B., Liu, F. et al., Non-steroidal anti-inflammatory drugs can lower amyloidogenic Abeta42 by inhibiting Rho. Science 2003, 302, 1215- 1217.
    • (2003) Science , vol.302 , pp. 1215-1217
    • Zhou, Y.1    Su, Y.2    Li, B.3    Liu, F.4
  • 76
    • 40349111175 scopus 로고    scopus 로고
    • Therapeutic potential of gamma-secretase inhibitors and modulators
    • Imbimbo, B. P., Therapeutic potential of gamma-secretase inhibitors and modulators. Curr. Top Med. Chem. 2008, 8, 54- 61.
    • (2008) Curr. Top Med. Chem. , vol.8 , pp. 54-61
    • Imbimbo, B.P.1
  • 77
    • 0042711005 scopus 로고    scopus 로고
    • Olive oil isochromans inhibit human platelet reactivity
    • Togna, G. I., Togna, A. R., Franconi, M., Olive oil isochromans inhibit human platelet reactivity. J. Nutr. 2003, 133, 2532- 2536.
    • (2003) J. Nutr. , vol.133 , pp. 2532-2536
    • Togna, G.I.1    Togna, A.R.2    Franconi, M.3
  • 78
    • 0035188011 scopus 로고    scopus 로고
    • The metabolic availability of dietary triacylglycerols from two high oleic oils during the postprandial period does not depend on the amount of oleic acid ingested by healthy men
    • Abia, R., Pacheco, Y. M., Perona, J. S., Montero, E. et al., The metabolic availability of dietary triacylglycerols from two high oleic oils during the postprandial period does not depend on the amount of oleic acid ingested by healthy men. J. Nutr. 2001, 131, 59- 65.
    • (2001) J. Nutr. , vol.131 , pp. 59-65
    • Abia, R.1    Pacheco, Y.M.2    Perona, J.S.3    Montero, E.4
  • 79
    • 67449147095 scopus 로고    scopus 로고
    • Squalene: A natural antioxidant
    • Amarowicz, R., Squalene: A natural antioxidant? Eur. J. Lipid Sci. Technol. 2009, 111, 411- 412.
    • (2009) Eur. J. Lipid Sci. Technol. , vol.111 , pp. 411-412
    • Amarowicz, R.1
  • 81
    • 68249135718 scopus 로고    scopus 로고
    • Adipose tissue: The new endocrine organ? A review article
    • Wozniak, S. E., Gee, L. L., Wachtel, M. S., Frezza, E. E., Adipose tissue: The new endocrine organ? A review article. Dig. Dis. Sci. 2009, 54, 1847- 1856.
    • (2009) Dig. Dis. Sci. , vol.54 , pp. 1847-1856
    • Wozniak, S.E.1    Gee, L.L.2    Wachtel, M.S.3    Frezza, E.E.4
  • 82
    • 19944433652 scopus 로고    scopus 로고
    • Visfatin: A protein secreted by visceral fat that mimics the effects of insulin
    • Fukuhara, A., Matsuda, M., Nishizawa, M., Segawa, K. et al., Visfatin: A protein secreted by visceral fat that mimics the effects of insulin. Science 2005, 307, 426- 430.
    • (2005) Science , vol.307 , pp. 426-430
    • Fukuhara, A.1    Matsuda, M.2    Nishizawa, M.3    Segawa, K.4
  • 83
    • 0036261264 scopus 로고    scopus 로고
    • TNFalpha expression of subcutaneous adipose tissue in obese and morbid obese females: Relationship to adipocyte LPL activity and leptin synthesis
    • Bulló, M., Garcia-Lorda, P., Peinado-Onsurbe, J., Hernández, M. et al., TNFalpha expression of subcutaneous adipose tissue in obese and morbid obese females: Relationship to adipocyte LPL activity and leptin synthesis. Int. J. Obes. 2002, 26, 652- 658.
    • (2002) Int. J. Obes. , vol.26 , pp. 652-658
    • Bulló, M.1    Garcia-Lorda, P.2    Peinado-Onsurbe, J.3    Hernández, M.4
  • 84
    • 0142248881 scopus 로고    scopus 로고
    • Systemic inflammation, adipose tissue tumor necrosis factor, and leptin expression
    • Bulló, M., Garcia-Lorda, P., Megias, I., Salas-Salvadó, J., Systemic inflammation, adipose tissue tumor necrosis factor, and leptin expression. Obes. Res. 2003, 11, 525- 531.
    • (2003) Obes. Res. , vol.11 , pp. 525-531
    • Bulló, M.1    Garcia-Lorda, P.2    Megias, I.3    Salas-Salvadó, J.4
  • 85
    • 0348230958 scopus 로고    scopus 로고
    • Obesity is associated with macrophage accumulation in adipose tissue
    • Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., et al., Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 2003, 112, 1796- 1808.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1796-1808
    • Weisberg, S.P.1    McCann, D.2    Desai, M.3    Rosenbaum, M.4
  • 86
    • 27444437321 scopus 로고    scopus 로고
    • Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
    • Cinti, S., Mitchell, G., Barbatelli, G., Murano, I. et al., Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J. Lipid Res. 2005, 46, 2347- 2355.
    • (2005) J. Lipid Res. , vol.46 , pp. 2347-2355
    • Cinti, S.1    Mitchell, G.2    Barbatelli, G.3    Murano, I.4
  • 87
    • 0034625079 scopus 로고    scopus 로고
    • Elevation of tumor necrosis factor-alpha and increased risk of recurrent coronary events after myocardial infarction
    • Ridker, P. M., Rifai, N., Pfeffer, M., Sacks, F. et al., Elevation of tumor necrosis factor-alpha and increased risk of recurrent coronary events after myocardial infarction. Circulation 2000, 101, 2149- 2153.
    • (2000) Circulation , vol.101 , pp. 2149-2153
    • Ridker, P.M.1    Rifai, N.2    Pfeffer, M.3    Sacks, F.4
  • 88
    • 0041568670 scopus 로고    scopus 로고
    • TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes
    • Souza, S. C., Palmer, H. J., Kang, Y. H., Yamamoto, M. T. et al., TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes. J. Cell Biochem. 2003, 89, 1077- 1086.
    • (2003) J. Cell Biochem. , vol.89 , pp. 1077-1086
    • Souza, S.C.1    Palmer, H.J.2    Kang, Y.H.3    Yamamoto, M.T.4
  • 90
    • 33745896155 scopus 로고    scopus 로고
    • Recent advances in the relationship between obesity, inflammation, and insulin resistance
    • Bastard, J. P., Maachi, M., Lagathu, C., Kim, M. J. et al., Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur. Cytokine Netw. 2006, 17, 4- 12.
    • (2006) Eur. Cytokine Netw. , vol.17 , pp. 4-12
    • Bastard, J.P.1    Maachi, M.2    Lagathu, C.3    Kim, M.J.4
  • 91
    • 36249017935 scopus 로고    scopus 로고
    • Minor polar compounds extra-virgin olive oil extract (MPC-OOE) inhibits NF-kappa B translocation in human monocyte/macrophages
    • Brunelleschi, S., Bardelli, C., Amoruso, A., Gunella, G. et al., Minor polar compounds extra-virgin olive oil extract (MPC-OOE) inhibits NF-kappa B translocation in human monocyte/macrophages. Pharmacol. Res. 2007, 56, 542- 549.
    • (2007) Pharmacol. Res. , vol.56 , pp. 542-549
    • Brunelleschi, S.1    Bardelli, C.2    Amoruso, A.3    Gunella, G.4
  • 92
    • 0033397867 scopus 로고    scopus 로고
    • Dietary fat and breast cancer
    • Willett, W. C., Dietary fat and breast cancer. Toxicol. Sci. 1999, 52, 127- 146.
    • (1999) Toxicol. Sci. , vol.52 , pp. 127-146
    • Willett, W.C.1
  • 93
    • 0037256369 scopus 로고    scopus 로고
    • Olive-oil consumption and cancer risk
    • Filik, L., Ozyilkan, O., Olive-oil consumption and cancer risk. Eur. J. Clin. Nutr. 2003, 57, 191.
    • (2003) Eur. J. Clin. Nutr. , vol.57 , pp. 191
    • Filik, L.1    Ozyilkan, O.2
  • 94
    • 4043056468 scopus 로고    scopus 로고
    • High-fat corn oil diet promotes the development of high histologic grade rat DMBA induced mammary adenocarcinomas, while high olive oil diet does not
    • Costa, I., Moral, R., Solanas, M., Escrich, E., High-fat corn oil diet promotes the development of high histologic grade rat DMBA induced mammary adenocarcinomas, while high olive oil diet does not. Breast Cancer Res. Treat. 2004, 86, 225- 235.
    • (2004) Breast Cancer Res. Treat. , vol.86 , pp. 225-235
    • Costa, I.1    Moral, R.2    Solanas, M.3    Escrich, E.4
  • 95
    • 22744447495 scopus 로고    scopus 로고
    • Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor
    • Hamdi, H. K., Castellon, R., Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor. Biochem. Biophys. Res. Commun. 2005, 334, 769- 778.
    • (2005) Biochem. Biophys. Res. Commun. , vol.334 , pp. 769-778
    • Hamdi, H.K.1    Castellon, R.2
  • 96
    • 33749481920 scopus 로고    scopus 로고
    • Olive fruit extracts inhibit proliferation and induce apoptosis in HT-29 human colon cancer cells
    • Juan, M. E., Wenzel, U., Ruiz-Gutierrez, V., Daniel, H., Planas, J. M., Olive fruit extracts inhibit proliferation and induce apoptosis in HT-29 human colon cancer cells. J. Nutr. 2006, 136, 2553- 2557.
    • (2006) J. Nutr. , vol.136 , pp. 2553-2557
    • Juan, M.E.1    Wenzel, U.2    Ruiz-Gutierrez, V.3    Daniel, H.4    Planas, J.M.5
  • 97
    • 33845904631 scopus 로고    scopus 로고
    • Mediterranean dietary traditions for the molecular treatment of human cancer: Anti-oncogenic actions of the main olive oil's monounsaturated fatty acid oleic acid (18:1n-9)
    • Menendez, J. A., Lupu, R., Mediterranean dietary traditions for the molecular treatment of human cancer: Anti-oncogenic actions of the main olive oil's monounsaturated fatty acid oleic acid (18:1n-9). Curr. Pharm. Biotechnol. 2006, 7, 495- 502.
    • (2006) Curr. Pharm. Biotechnol. , vol.7 , pp. 495-502
    • Menendez, J.A.1    Lupu, R.2
  • 98
    • 33744780262 scopus 로고    scopus 로고
    • A genomic explanation connecting "Mediterranean diet", olive oil and cancer: Oleic acid, the main monounsaturated fatty acid of olive oil, induces formation of inhibitory "PEA3 transcription factor-PEA3 DNA binding site" complexes at the Her-2/neu (erbB-2) oncogene promoter in breast, ovarian and stomach cancer cells
    • Menendez, J. A., Papadimitropoulou, A., Vellon, L., Lupu, L., A genomic explanation connecting "Mediterranean diet", olive oil and cancer: Oleic acid, the main monounsaturated fatty acid of olive oil, induces formation of inhibitory "PEA3 transcription factor-PEA3 DNA binding site" complexes at the Her-2/neu (erbB-2) oncogene promoter in breast, ovarian and stomach cancer cells. Eur. J. Cancer. 2006, 42, 2425- 2432.
    • (2006) Eur. J. Cancer. , vol.42 , pp. 2425-2432
    • Menendez, J.A.1    Papadimitropoulou, A.2    Vellon, L.3    Lupu, L.4
  • 99
    • 62149134185 scopus 로고    scopus 로고
    • Fatty acid synthase: Association with insulin resistance, type 2 diabetes, and cancer
    • Menendez, J. A., Vazquez-Martin, A., Ortega, F. J., Fernandez-Real, J. M., Fatty acid synthase: Association with insulin resistance, type 2 diabetes, and cancer. Clin. Chem. 2009, 55, 425- 438.
    • (2009) Clin. Chem. , vol.55 , pp. 425-438
    • Menendez, J.A.1    Vazquez-Martin, A.2    Ortega, F.J.3    Fernandez-Real, J.M.4
  • 100
    • 34249863300 scopus 로고    scopus 로고
    • Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin™) in HER2-overexpressing breast cancer cells
    • DOI: 10.1186/1471-2407-7-80.
    • Menendez, J. A., Vazquez-Martin, A., Colomer, R., Brunet, J. et al., Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin™) in HER2-overexpressing breast cancer cells. BMC Cancer 2007, 7, 80. DOI: 10.1186/1471-2407-7-80.
    • (2007) BMC Cancer , vol.7 , pp. 80
    • Menendez, J.A.1    Vazquez-Martin, A.2    Colomer, R.3    Brunet, J.4
  • 101
    • 60549105908 scopus 로고    scopus 로고
    • TabAnti-HER2 (erbB-2) oncogene effects of phenolic compounds directly isolated from commercial Extra-Virgin Olive Oil (EVOO)
    • Menendez, J. A., Vazquez-Martin, A., Garcia-Villalba, R., Carrasco-Pancorbo, A. et al., TabAnti-HER2 (erbB-2) oncogene effects of phenolic compounds directly isolated from commercial Extra-Virgin Olive Oil (EVOO). BMC Cancer 2008, 8, 377.
    • (2008) BMC Cancer , vol.8 , pp. 377
    • Menendez, J.A.1    Vazquez-Martin, A.2    Garcia-Villalba, R.3    Carrasco-Pancorbo, A.4
  • 102
    • 60749117034 scopus 로고    scopus 로고
    • Extra-virgin olive oil polyphenols inhibit HER2 (erbB-2)-induced malignant transformation in human breast epithelial cells: Relationship between the chemical structures of extra-virgin olive oil secoiridoids and lignans and their inhibitory activities on the tyrosine kinase activity of HER2
    • Menendez, J. A., Vazquez-Martin, A., Oliveras-Ferraros, C., Garcia-Villalba, R. et al., Extra-virgin olive oil polyphenols inhibit HER2 (erbB-2)-induced malignant transformation in human breast epithelial cells: Relationship between the chemical structures of extra-virgin olive oil secoiridoids and lignans and their inhibitory activities on the tyrosine kinase activity of HER2. Int. J. Oncol. 2009, 34, 43- 451.
    • (2009) Int. J. Oncol. , vol.34 , pp. 43-451
    • Menendez, J.A.1    Vazquez-Martin, A.2    Oliveras-Ferraros, C.3    Garcia-Villalba, R.4
  • 103
    • 0042924150 scopus 로고    scopus 로고
    • Modulation of meal pattern in the rat by the anorexic lipid mediator oleoylethanolamide
    • Gaetani, S., Oveisi, F., Piomelli, D., Modulation of meal pattern in the rat by the anorexic lipid mediator oleoylethanolamide. Neuropsychopharmacology 2003, 28, 1311- 1316.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1311-1316
    • Gaetani, S.1    Oveisi, F.2    Piomelli, D.3
  • 104
    • 0041321275 scopus 로고    scopus 로고
    • Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha
    • Fu, J., Gaetani, S., Oveisi, F., Lo, J. et al., Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha. Nature 2003, 425, 90- 93.
    • (2003) Nature , vol.425 , pp. 90-93
    • Fu, J.1    Gaetani, S.2    Oveisi, F.3    Lo, J.4
  • 105
    • 19444372260 scopus 로고    scopus 로고
    • Oleoylethanolamide, an endogenous PPAR-alpha agonist, lowers body weight and hyperlipidemia in obese rats
    • Fu, J., Oveisi, F., Gaetani, S., Lin, E., Piomelli, D., Oleoylethanolamide, an endogenous PPAR-alpha agonist, lowers body weight and hyperlipidemia in obese rats. Neuropharmacology 2005, 48, 1147- 1153.
    • (2005) Neuropharmacology , vol.48 , pp. 1147-1153
    • Fu, J.1    Oveisi, F.2    Gaetani, S.3    Lin, E.4    Piomelli, D.5
  • 106
    • 17044393107 scopus 로고    scopus 로고
    • Regulation of food intake by oleoylethanolamide CMLS
    • LoVerme, J., Gaetani, S., Fu, J., Oveisi, F. et al., Regulation of food intake by oleoylethanolamide CMLS. Cell Mol. Life Sci. 2005, 62, 708- 716.
    • (2005) Cell Mol. Life Sci. , vol.62 , pp. 708-716
    • LoVerme, J.1    Gaetani, S.2    Fu, J.3    Oveisi, F.4
  • 107
    • 46749153452 scopus 로고    scopus 로고
    • The element of surprise
    • Piomelli, D., The element of surprise. Nat. Med. 2008, 14, 720- 721.
    • (2008) Nat. Med. , vol.14 , pp. 720-721
    • Piomelli, D.1
  • 108
    • 52749087007 scopus 로고    scopus 로고
    • The lipid messenger OEA links dietary fat intake to satiety
    • Schwartz, G. J., Fu, J., Astarita, G., Li, X. et al., The lipid messenger OEA links dietary fat intake to satiety. Cell Metab. 2008, 8, 281- 288.
    • (2008) Cell Metab. , vol.8 , pp. 281-288
    • Schwartz, G.J.1    Fu, J.2    Astarita, G.3    Li, X.4
  • 109
    • 79955767686 scopus 로고    scopus 로고
    • Sympathetic activity controls fat-induced oleoylethanolamide signaling in small intestine
    • Fu, J., Dipatrizio, N. V., Guijarro, A., Schwartz, G. J. et al., Sympathetic activity controls fat-induced oleoylethanolamide signaling in small intestine. J. Neurosci. 2011, 31, 5730- 5736.
    • (2011) J. Neurosci. , vol.31 , pp. 5730-5736
    • Fu, J.1    Dipatrizio, N.V.2    Guijarro, A.3    Schwartz, G.J.4
  • 110
    • 33747154772 scopus 로고    scopus 로고
    • Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network
    • Bookout, A. L., Jeong, Y., Downes, M., Yu, R. T. et al., Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell 2006, 126, 789- 799.
    • (2006) Cell , vol.126 , pp. 789-799
    • Bookout, A.L.1    Jeong, Y.2    Downes, M.3    Yu, R.T.4
  • 111
    • 50649083750 scopus 로고    scopus 로고
    • Targeted enhancement of oleoylethanolamide production in proximal small intestine induces across-meal satiety in rats
    • Fu, J., Kim, J., Oveisi, F., Astarita, G., Piomelli, D., Targeted enhancement of oleoylethanolamide production in proximal small intestine induces across-meal satiety in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2008, 295, 45- 50.
    • (2008) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.295 , pp. 45-50
    • Fu, J.1    Kim, J.2    Oveisi, F.3    Astarita, G.4    Piomelli, D.5
  • 112
    • 36048929554 scopus 로고    scopus 로고
    • Highly sensitive upregulation of apolipoprotein A-IV by peroxisome proliferator-activated receptor alpha (PPARalpha) agonist in human hepatoma cells
    • Nagasawa, M., Akasaka, Y., Ide, T., Hara, T. et al., Highly sensitive upregulation of apolipoprotein A-IV by peroxisome proliferator-activated receptor alpha (PPARalpha) agonist in human hepatoma cells. Biochem. Pharmacol. 2007, 74, 1738- 1746.
    • (2007) Biochem. Pharmacol. , vol.74 , pp. 1738-1746
    • Nagasawa, M.1    Akasaka, Y.2    Ide, T.3    Hara, T.4
  • 113
    • 56449095685 scopus 로고    scopus 로고
    • Role of endocannabinoids and their analogues in obesity and eating disorders
    • Gaetani, S., Kaye, W. H., Cuomo, V., Piomelli, D., Role of endocannabinoids and their analogues in obesity and eating disorders. Eat Weight Disord. 2008, 13, 42- 48.
    • (2008) Eat Weight Disord. , vol.13 , pp. 42-48
    • Gaetani, S.1    Kaye, W.H.2    Cuomo, V.3    Piomelli, D.4
  • 114
    • 37449000478 scopus 로고    scopus 로고
    • The cannabinoid CB1 receptor antagonist SR 141716A (Rimonabant) enhances the metabolic benefits of long-term treatment with oleoylethanolamide in Zucker rats
    • Serrano, A., Del Arco, I., Javier, F., Pavón, M. et al., The cannabinoid CB1 receptor antagonist SR 141716A (Rimonabant) enhances the metabolic benefits of long-term treatment with oleoylethanolamide in Zucker rats. Neuropharmacology 2008, 54, 226- 234.
    • (2008) Neuropharmacology , vol.54 , pp. 226-234
    • Serrano, A.1    Del Arco, I.2    Javier, F.3    Pavón, M.4
  • 116
    • 67650364418 scopus 로고    scopus 로고
    • Characterization of human gene expression changes after olive oil ingestion: An exploratory approach
    • Konstantinidou, V., Khymenets, O., Fito, M., De La Torre, R. et al., Characterization of human gene expression changes after olive oil ingestion: An exploratory approach. Folia Biol. (Praha) 2009, 55, 85- 91.
    • (2009) Folia Biol. (Praha) , vol.55 , pp. 85-91
    • Konstantinidou, V.1    Khymenets, O.2    Fito, M.3    De La Torre, R.4
  • 117
    • 64949159112 scopus 로고    scopus 로고
    • Mononuclear cell transcriptome response after sustained virgin olive oil consumption in humans: An exploratory nutrigenomics study
    • Khymenets, O., Fito, M., Covas, M. I., Farré, M. et al., Mononuclear cell transcriptome response after sustained virgin olive oil consumption in humans: An exploratory nutrigenomics study. Omics 2009, 13, 7- 19.
    • (2009) Omics , vol.13 , pp. 7-19
    • Khymenets, O.1    Fito, M.2    Covas, M.I.3    Farré, M.4
  • 118
    • 77954451328 scopus 로고    scopus 로고
    • In vivo nutrigenomic effects of virgin olive oil polyphenols within the frame of the Mediterranean diet: A randomized controlled trial
    • Konstantinidou, V., Covas, M. I., Muñoz-Aguayo, D., Khymenets, O. et al., In vivo nutrigenomic effects of virgin olive oil polyphenols within the frame of the Mediterranean diet: A randomized controlled trial. FASEB J. 2010, 24, 2546- 2557.
    • (2010) FASEB J. , vol.24 , pp. 2546-2557
    • Konstantinidou, V.1    Covas, M.I.2    Muñoz-Aguayo, D.3    Khymenets, O.4
  • 119
    • 77950930524 scopus 로고    scopus 로고
    • Gene expression changes in mononuclear cells in patients with metabolic syndrome after acute intake of phenol-rich virgin olive oil
    • Camargo, A., Ruano, J., Fernandez, J. M., Parnell, L. D. et al., Gene expression changes in mononuclear cells in patients with metabolic syndrome after acute intake of phenol-rich virgin olive oil. BMC Genomics 2010, 20, 253- 264.
    • (2010) BMC Genomics , vol.20 , pp. 253-264
    • Camargo, A.1    Ruano, J.2    Fernandez, J.M.3    Parnell, L.D.4
  • 120
    • 79955825061 scopus 로고    scopus 로고
    • Crude phenolic extracts from extra virgin olive oil circumvent de novo breast cancer resistance to HER1/HER2-targeting drugs by inducing GADD45-sensed cellular stress, G2/M arrest and hyperacetylation of Histone H3
    • Oliveras-Ferraros, C., Fernández-Arroyo, S., Vazquez-Martin, A., Lozano-Sánchez, J. et al., Crude phenolic extracts from extra virgin olive oil circumvent de novo breast cancer resistance to HER1/HER2-targeting drugs by inducing GADD45-sensed cellular stress, G2/M arrest and hyperacetylation of Histone H3. Int. J. Oncol. 2011, 38, 1533- 1547.
    • (2011) Int. J. Oncol. , vol.38 , pp. 1533-1547
    • Oliveras-Ferraros, C.1    Fernández-Arroyo, S.2    Vazquez-Martin, A.3    Lozano-Sánchez, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.