Mononuclear cell transcriptome response after sustained virgin olive oil consumption in humans: An exploratory nutrigenomics study

OMICS A Journal of Integrative Biology

Volumn 13, Issue 1, 2009, Pages 7-19

  Khymenets, Olha ^a,b   Fitó, Montserat ^a,b   Covas, María Isabel ^a,b   Farré, Magí ^a,c   Pujadas, Maria Antonia ^a,b   Muñoz, Daniel ^a   Konstantinidou, Valentini ^a,b   De La Torre, Rafael ^a,b,d  

^a HOSPITAL DEL MAR   (Spain)

^b Instituto de Salud Carlos III   (Spain)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^d UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

NEURONAL APOPTOSIS INHIBITORY PROTEIN; OLIVE OIL; RNA; TRANSCRIPTOME; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

ADAM17 GENE; ADULT; ALDH1A1 GENE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CONTROLLED STUDY; DIET SUPPLEMENTATION; DISEASE COURSE; ERCC5 GENE; FEMALE; GENE; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; LIAS GENE; MALE; MEDITERRANEAN DIET; NORMAL HUMAN; NUTRIGENOMICS; OGT GENE; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMERASE CHAIN REACTION; PPARBP GENE; PRIORITY JOURNAL; TN FSF10 GENE; USP48 GENE; XRCC5 GENE;

ADULT; ATHEROSCLEROSIS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; DIET, MEDITERRANEAN; DIETARY FATS; DIETARY SUPPLEMENTS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; LEUKOCYTES, MONONUCLEAR; LIPIDS; MALE; NUTRIGENOMICS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLANT OILS; YOUNG ADULT;

EID: 64949159112     PISSN: 15362310     EISSN: None     Source Type: Journal    
DOI: 10.1089/omi.2008.0079     Document Type: Article

References (78)

1. Abia, R., Pacheco, Y.M., Perona, J.S., Montero, E., Muriana, F.J., and Ruiz-Gutiérrez, V. (2001). The metabolic availability of dietary triacylglycerols from two high oleic oils during the postprandial period does not depend on the amount of oleic acid ingested by healthy men. J Nutr 131, 59-65.
2. Allman-farinelli, M.A., Gomes, K., Favaloro, E.J., and Petocz, P. (2005). A diet rich in high-oleic-acid sunflower oil favorably alters low-density lipoprotein cholesterol, triglycerides, and factor VII coagulant activity. J Am Diet Assoc 105, 1071-1079.
3. Badeau, M., Adlercreutz, H., Kaihovaara, P., and Tikkanen, M.J. (2005). Estrogen A-ring structure and antioxidative effect on lipoproteins. J Steroid Biochem Mol Biol 96, 271-278.
4. Bast, A., and Haenen, G.R. (2003). Lipoic acid: a multifunctional antioxidant. Biofactors 17, 207-213.
5. Blankenberg, S., Barbaux, S., and Tiret, L. (2003). Adhesion molecules and atherosclerosis. Atherosclerosis 170, 191-203.
6. Brunner, E.J., Mosd l, A., Witte, D.R., Martikainen, P., Stafford, M., Shipley, M.J. et al. (2008). Dietary patterns and 15-y risks of major coronary events, diabetes, and mortality. Am J Clin Nutr 87, 1414-1421.
7. Chang, H.W., Kim, S.Y., Yi, S.L., Son, S.H., Song Do, Y., Moon, S.Y., et al. (2006). Expression of Ku80 correlates with sensitivities to radiation in cancer cell lines of the head and neck. Oral Oncol 42, 979-986.
8. Choudhary, S., Xiao, T., Vergara, L.A., Srivastava, S., Nees, D., Piatigorsky, J., et al. (2005). Role of aldehyde dehydrogenase isozymes in the defense of rat lens and human lens epithelial cells against oxidative stress. Invest Ophthalmol Vis Sci 46, 259-267.
9. Clément, V., Dunand-Sauthier, I., and Clarkson, S.G. (2006). Suppression of UV-induced apoptosis by the human DNA repair protein XPG. Cell Death Differ 13, 478-488.
10. Clément, V., Dunand-Sauthier, I., Wiznerowicz, M., and Clark-son, S.G. (2007). UV-induced apoptosis in XPG-deficient fi-broblasts involves activation of CD95 and caspases but not p53. DNA Repair (Amst) 6, 602-614.
11. Corona, G., Deiana, M., Incani, A., Vauzour, D., Dessí, M.A., and Spencer, J.P. (2007). Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects. Biochem Biophys Res Commun 362, 606-611.
12. Covas, M.I., Nyyssönen, K., Poulsen, H.E., Kaikkonen, J., Zunft, H.J., Kiesewetter, H., et al., EUROLIVE Study Group. (2006). The effect of polyphenols in olive oil on heart disease risk factors: a randomized trial. Ann Intern Med 145, 333-341.
13. De Laat, W.L., Jaspers, N.G., and Hoeijmakers, J.H. (1999). Molecular mechanism of nucleotide excision repair. Genes Dev 13, 768-785.
14. Deveraux, Q.L., and Reed, J.C. (1999). IAP family proteins-suppressors of apoptosis. Genes Dev 13, 239-252.
15. Duan, S.Z., Ivashchenko, C.Y., Usher, M.G., and Mortensen, R.M. (2008). PPAR-gamma in the cardiovascular system. PPAR Res 2008, 745804.
16. Duplus, E., Glorian, M., and Forest, C. (2000). Fatty acid regulation of gene transcription. J Biol Chem 275, 30749-30752.
17. Esterbauer, H., Schaur, R.J., and Zollner, H. (1991). Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 11, 81-128.
18. Estruch, R., Martínez-González, M.A., Corella, D., Salas-Sal-vadó, J., Ruiz-Gutiérrez, V., Covas, M.I., et al., PREDIMED Study Investigators. (2006). Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial. Ann Intern Med 145, 1-11.
19. Fitó, M., Cladellas, M., De La Torre, R., Martí, J., Alcántara, M., Pujadas-Bastardes, M., et al. The members of the SOLOS Investigators. (2005). Antioxidant effect of virgin olive oil in patients with stable coronary heart disease: a randomized, crossover, controlled, clinical trial. Atherosclerosis 181, 149- 158.
20. Friedewald, W.T., Levy, R.I., and Fredrickson, D.S. (1972). Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracen-trifuge. Clin Chem 18, 499-502.
21. Fülöp, N., Marchase, R.B., and Chatham, J.C. (2007). Role of protein O-linked N-acetyl-glucosamine in mediating cell function and survival in the cardiovascular system. Cardiovasc Res 73, 288-297.
22. Ge, K., Cho, Y.W., Guo, H., Hong, T.B., Guermah, M., Ito, M., et al. (2008). Alternative mechanisms by which mediator subunit MED1/TRAP220 regulates peroxisome proliferator-activated receptor gamma-stimulated adipogenesis and target gene expression. Mol Cell Biol 28, 1081-1091.
23. Gimeno, E., Calero, E., Castellote, A.I., Lamuela-Raventos, R.M., De La Torre-Boronat, M.C., and Lopez-Sabater, M.C. (2000). Simultaneous determination od alpha-tocopherol and beta-carotene in olive oil by RP-HPLC. J Chromatogr A 881, 255-259.
24. Glisovic, T., Bachorik, J.L., Yong, J., and Dreyfuss, G. (2008). RNA-binding proteins and post-transcriptional gene regulation. FEBS Lett 582, 1977-1986.
25. Goldberg, A.L. (2003). Protein degradation and protection against misfolded or damaged proteins. Nature 426, 895-899.
26. Golks, A., Tran, T.T., Goetschy, J.F., and Guerini, D. (2007). Requirement for O-linked N-acetylglucosaminyltransferase in lymphocytes activation. EMBO J 26, 4368-4379.
27. Hashimoto, S., Nagai, S., Sese, J., Suzuki, T., Obata, A., Sato, T., et al. (2003). Gene expression profile in human leukocytes. Blood 101, 3509-3513.
28. Herrmann, J., Ciechanover, A., Lerman, L.O., and Lerman, A. (2004). The ubiquitin-proteasome system in cardiovascular diseases-a hypothesis extended. Cardiovasc Res 61, 11-21.
29. Holvoet, P., Mertens, A., Verhamme, P., Bogaerts, K., Beyens, G., Verhaeghe, R., et al. (2001). Circulating oxidized LDL is a useful marker for identifying patients with coronary artery disease. Arterioscler Thromb Vasc Biol 21, 844-848.
30. Iqbal, R., Anand, S., Ounpuu, S., Islam, S., Zhang, X., Rangara-jan, S., et al., INTERHEART Study Investigators. (2008). Dietary patterns and the risk of acute myocardial infarction in 52 countries: results of the INTERHEART study. Circulation 118, 1929-1937.
31. Kavurma, M.M., and Bennett, M.R. (2008). Expression, regula- tion and function of trail in atherosclerosis. Biochem Pharmacol 75, 1441-1450.
32. Kayagaki, N., Yamaguchi, N., Nakayama, M., Eto, H., Okumura, K., and Yagita, H. (1999). Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: a novel mechanism for the antitumor effects of type I IFNs. J Exp Med 189, 1451- 1460.
33. Kemp, T.J., Moore, J.M., and Griffith, T.S. (2004). Human B cells express functional TRAIL/Apo-2 ligand after CpG-contain-ing oligodeoxynucleotide stimulation. J Immunol 173, 892- 899.
34. Kempe, S., Kestler, H., Lasar, A., and Wirth, T. (2005). NF-kap-paB controls the global pro-inflammatory response in endo-thelial cells: evidence for the regulation of a pro-atherogenic program. Nucleic Acids Res 33, 5308-5319.
35. Khymenets, O., Ortuño, J., Fitó, M., Covas, M.A., Farré, M., and De La Torre, R. (2005). Evaluation of RNA isolation procedures from human blood and its application for gene expression studies (Sod-1, Sod-2). Anal Biochem 347, 156-158.
36. Kris-Etherton, P.M., Pearson, T.A., Wan, Y., Hargrove, R.L., Mo-riarty, K., Fishell, V., et al. (1999). High-monounsaturated fatty acid diets lower both plasma cholesterol and triacylglycerol concentrations. Am J Clin Nutr 70, 1009-1015.
37. Kromhout, D. (2001). Diet and cardiovascular diseases. J Nutr Health Aging 5, 144-149.
38. Kurz, M., Pischel, H., Hartung, H.P., and Kieseier, B.C. (2005). Tumor necrosis factor-alpha-converting enzyme is expressed in the inflamed peripheral nervous system. J Peripher Nerv Syst 10, 311-318.
39. Langheinrich, A.C., and Bohle, R.M. (2005). Atherosclerosis: humoral and cellular factors of inflammation. Virchows Arch 446, 101-111.
40. Langie, S.A., Knaapen, A.M., Houben, J.M., Van Kempen, F.C., De Hoon, J.P., Gottschalk, R.W., et al. (2007). The role of glu-tathione in the regulation of nucleotide excision repair during oxidative stress. Toxicol Lett 168, 302-309.
41. Li, N., Boyd, K., Dempsey, P.J., and Vignali, D.A. (2007). Non-cell autonomous expression of TNF-alpha-converting enzyme ADAM17 is required for normal lymphocyte development. J Immunol 178, 4214-4221.
42. Livak, K.J., and Schmittgen, T.D. (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C (T)) Method. Methods 25, 402-408.
43. Lockhart, P.J., Hulihan, M., Lincoln, S., Hussey, J., Skipper, L., Bisceglio, G., et al. (2004). Identification of the human ubiq-uitin specific protease 31 (USP31) gene: structure, sequence and expression analysis. DNA Seq 15, 9-14.
44. Machowetz, A., Poulsen, H.E., Gruendel, S., Weimann, A., Fitó, M., Marrugat, J., et al. (2007). Effect of olive oils on biomark-ers of oxidative DNA stress in Northern and Southern Europeans. FASEB J 21, 45-52.
45. Mahmoudi, M., Mercer, J., and Bennett, M. (2006). DNA damage and repair in atherosclerosis. Cardiovasc Res 71, 259- 268.
46. Martinon, F. (2007). Orchestration of pathogen recognition by inflammasome diversity: variations on a common theme. Eur J Immunol 137, 3003-3006.
47. Mauro, V.P., and Edelman, G.M. (2002). The ribosome filter hypothesis. Proc Natl Acad Sci USA 99, 12031-12036.
48. Meng, X., Li, Z.M., Zhou, Y.J., Cao, Y.L., and Zhang, J. (2008). Effect of the antioxidant alpha-lipoic acid on apoptosis in human umbilical vein endothelial cells induced by high glucose. Clin Exp Med 8, 43-49.
49. Mi, H., Guo, N., Kejariwal, A., and Thomas, P.D. (2007). PAN- THER version 6: protein sequence and function evolution data with expanded representation of biological pathways. Nucleic Acids Res 35, D247-D252.
50. Miró-Casas, E., Covas, M.I., Fitó, M., Farré- Albadalejo, M., Mar-rugat, J., and De La Torre, R. (2003). Tyrosol and hydroxyty-rosol are absorbed from moderate and sustained doses of virgin olive oil in humans. Eur J Clin Nutr 57, 186-190.
51. Moini, H., Packer, L., and Saris, N.E. (2002). Antioxidant and prooxidant activities of alpha-lipoic acid and dihydrolipoic acid.Toxicol Appl Pharmacol 182, 84-90.
52. Morey, J.S., Ryan, J.C., and Van Dolah, F.M. (2006). Microarray validation: factors influencing correlation between oligonu-cleotide microarrays and real-time PCR. Biol Proced Online 8, 175-193.
53. Murano, K., Okuwaki, M., Hisaoka, M., and Nagata, K. (2008). Transcription regulation of rRNA gene by a multi-functional nucleolar protein, B23/nucleophosmin through its histone chaperone activity. Mol Cell Biol 28, 3114-3126.
54. Ohtsu, H., Dempsey, P.J., Frank, G.D., Brailoiu, E., Higuchi, S., Suzuki, H., et al. (2006). ADAM17 mediates epidermal growth factor receptor transactivation and vascular smooth muscle cell hypertrophy induced by angiotensin II. Arterioscler Thromb Vasc Biol 26, e133-e137.
55. Ordovas, J.M., Kaput, J., and Corella, D. (2007). Nutrition in the genomics era: cardiovascular disease risk and the Mediterranean diet. Mol Nutr Food Res 51, 1293-1299.
56. Palmer, C., Diehn, M., Alizadeh, A.A., and Brown, P.O. (2006). Cell-type specific gene expression profiles of leukocytes in human peripheral blood. BMC Genomics 7, 115.
57. Rodriguez-Rodriguez, R., Herrera, M.D., De Sotomayor, M.A., and Ruiz-Gutierrez, V. (2007). Pomace olive oil improves en-dothelial function in spontaneously hypertensive rats by increasing endothelial nitric oxide synthase expression. Am J Hypertens 20, 728-734.
58. Ross, R. (1999). Atherosclerosis is an inflammatory disease. Am Heart J 138, S419-S420.
59. Ruiz-Gutiérrez, V., Morgado, N., Prada, J.L., Pérez- Jiménez, F., and Suriana, F.J. (1998). Composition of human VLDL tria-cylglycerols after ingestion of olive oil and high oleic sunflower oil. J Nutr 128, 570-576.
60. Satue, M.T., Lopez, M.C., and Agramont, A. (1994). Fatty acid composition of trout oil. Food Chem 50, 363-365.
61. Singleton, V.L., and Ross, J.A. (1965). Colorimetry of total phe-nolics with phosphomolybdic-phosphotungstic acid reagent. Am J Enol Vitic 116, 144-158.
62. Solomon, A., Akabayov, B., Frenkel, A., Milla, M.E., and Sagi, I. (2007). Key feature of the catalytic cycle of TNF-alpha converting enzyme involves communication between distal protein sites and the enzyme catalytic core. Proc Natl Acad Sci USA 104, 4931-4936.
63. Srinath Reddy, K., and Katan, M.B. (2004). Diet, nutrition and the prevention of hypertension and cardiovascular diseases. Public Health Nutr 7, 167-186.
64. Stanchi, F., Bertocco, E., Toppo, S., Dioguardi, R., Simionati, B., Cannata, N., et al. (2001). Characterization of 16 novel human genes showing high similarity to yeast sequences. Yeast 18, 69-80.
65. Swaminathan, V., Kishore, A.H., Febitha, K.K., and Kundu, T.K. (2005). Human histone chaperone nucleophosmin enhances acetylation-dependent chromatin transcription. Mol Cell Biol 25, 7534-7545.
66. Tellier, E., Canault, M., Poggi, M., Bonardo, B., Nicolay, A., Alessi, M.C., et al. (2008). HDLs activate ADAM17-dependent shedding. J Cell Physiol 214, 687-693.
67. Thacker, J., and Zdzienicka, M.Z. (2004). The XRCC genes: expanding roles in DNA double-strand break repair. DNA Repair (Amst) 3, 1081-1090.
68. Thomas, P.D., Campbell, M.J., Kejariwal, A., Mi, H., Karlak, B., Daverman, R., et al. (2003). PANTHER: a library of protein families and subfamilies indexed by function. Genome Res 13, 2129-2141.
69. Thoas, P.D., Kejariwal, A., Guo, N., Mi, H., Campbell, M.J., Muruganujan, A., et al. (2006). Applications for protein sequence-function evolution data: mRNA/protein expression analysis and coding SNP scoring tools. Nucleic Acids Res 34, W645-W650.
70. Trichopoulou, A., Kouris-Blazos, A., Wahlovist, M.L., Gnardel-lis, C., Lagiou, P., Polychronopoulos, E., et al. (1995). Diet and overall survival in elderly people. BMJ 311, 1457-1460.
71. Trichopoulou, A., Costacou, T., Bamia, C., and Trichopoulos, D. (2003). Adherence to a Mediterranean diet and survival in a Greek population. N Engl J Med 348, 2599-2608.
72. Vasiliou, V., Pappa, A., and Petersen, D.R. (2000). Role of aldehyde dehydrogenases in endogenous and xenobiotic metabolism. Chem Biol Interact 129, 1-19.
73. Vieira, O., Escargueil-Blanc, I., Jürgens, G., Borner, C., Almeida, L., Salvayre, R., et al. (2000). Oxidized LDLs alter the activity of the ubiquitin-proteasome pathway: potential role in oxidized LDL-induced apoptosis. FASEB J 14, 532-542.
74. Weinbrenner, T., Fitó, M., De La Torre, R., Saez, G.T., Rijken, P., Tormos, C., et al. (2004). Olive oils high in phenolic compounds modulate oxidative/antioxidative status in men. J Nutr 134, 2314-2321.
75. Zachara, N.E., and Hart, G.W. (2006). Cell signaling, the essential role of O-GlcNAc. Biochim Biophys Acta 1761, 599-617.
76. Zachara, N.E., O'Donnell, N., Cheung, W.D., Mercer, J.J., Marth, J.D., and Hart, G.W. (2004). Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells. J Biol Chem 279, 30133-30142.
77. Zhang, W.J., Bird, K.E., McMillen, T.S., Leboeuf, R.C., Hagen, T.M., and Frei, B. (2008). Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice. Circulation 117, 421-428.
78. Zhou, Z., Connell, M.C., and MacEwan, D.J. (2007). TNFR1-in-duced NF-kappaB, but not ERK, p38MAPK or JNK activation, mediates TNF-induced ICAM-1 and VCAM-1 expression on endothelial cells. Cell Signal 19, 1238-1248.