Ibuprofen-like activity in extra-virgin olive oil

Nature

Volumn 437, Issue 7055, 2005, Pages 45-46

  Beauchamp, Gary K ^a   Keast, Russell S J ^a,c   Morel, Diane ^a   Lin, Jianming ^e   Pika, Jana ^e   Han, Qiang ^b   Lee, Chi Ho ^a,d   Smith, Amos B ^a,b   Breslin, Paul A S ^a  

^a UNIVERSITY OF THE SCIENCES   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c RMIT UNIVERSITY   (Australia)

^d Konkuk University   (South Korea)

^e Firmenich   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; FLAMMABILITY;

IBUPROFEN; OLIVE OIL;

VEGETABLE OILS;

ANTIINFLAMMATORY AGENT; CAFFEIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; IBUPROFEN; INDOMETACIN; NORDIHYDROGUAIARETIC ACID; OLEOCANTHAL; OLIVE OIL; UNCLASSIFIED DRUG; ALDEHYDE; EDIBLE OIL; NONSTEROID ANTIINFLAMMATORY AGENT; PHENOL DERIVATIVE; PROSTAGLANDIN SYNTHASE INHIBITOR; VEGETABLE OIL;

ENZYME;

ANALGESIA; ANTIINFLAMMATORY ACTIVITY; ARTICLE; DRUG SYNTHESIS; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; CHEMICAL STRUCTURE; CHEMISTRY; ISOLATION AND PURIFICATION; OLIVE TREE;

ALDEHYDES; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYCLOOXYGENASE INHIBITORS; DIETARY FATS, UNSATURATED; IBUPROFEN; MOLECULAR STRUCTURE; OLEA; PHENOLS; PLANT OILS;

EID: 24344452961     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/437045a     Document Type: Article

References (13)

1. Breslin, P. A. S., Gingerich, T. N. & Green, B. G. Chem. Sens. 26, 55-66 (2001).
2. Andrewes, P., Busch, J. L. H. C., De Joode, T., Groenewegen, A. & Alexandre, H. J. Agric. Food Chem. 51, 1415-1420 (2003).
3. Fischer, R., Griffen, F., Archer, R. C., Zinsmeister, S. C. & Jastram, P. S. Nature 207, 1049-1053 (1965).
4. Vane, J. R. & Botting, R. M. Inflamm. Res. 44, 1-10 (1995).
5. Harris, R. E., Beebe-Donk, J., Doss, H. & Burr Doss, D. Oncol. Rep. 13, 559-583 (2005).
6. Zhou, Y. et al. Science 302, 1215-1217 (2003).
7. Hu, F. N. Engl. J. Med. 348, 2595-2596 (2003).
8. Tuck, K., Freeman, M., Hayball, P., Stretch, G. & Stupans, I. J. Nutr. 131, 1993-1996 (2001).
9. Miro-Casas, E. et al. Clin. Chem. 49, 945-952 (2003).
10. Hennekens, C. H. Am. J. Man. Care 8 (suppl.), 691-700 (2002).
11. Lefer, A. M., Muller, H. F. & Smith, J. B. Br. J.Pharmacol. 83, 125-130 (1984).
12. Togna, G. I., Togna, A. R., Franconi, M., Marra, C. & Guiso, M. J. Nutr. 133, 2532-2536 (2003).
13. Mitchell, J. A. et al. Proc. Natl Acad. Sci. USA 90, 11693-11697 (1993).