-
1
-
-
64049102360
-
Dynamic localization of hepatocellular transporters in health and disease
-
M. G. Roma, F. A. Crocenzi, and A. D. Mottino: Dynamic localization of hepatocellular transporters in health and disease. World J. Gastroenterol. 14, 6786-6801 (2008).
-
(2008)
World J. Gastroenterol
, vol.14
, pp. 6786-6801
-
-
Roma, M.G.1
Crocenzi, F.A.2
Mottino, A.D.3
-
2
-
-
0033459277
-
The role of the sinusoidal endothelium in liver function
-
J. Reichen, The Role of the Sinusoidal Endothelium in Liver Function. News Physiol Sci. 14, 117-121 (1999).
-
(1999)
News Physiol Sci
, vol.14
, pp. 117-121
-
-
Reichen, J.1
-
3
-
-
63449107281
-
Physiology of bile secretion
-
A. Esteller, Physiology of bile secretion. World J. Gastroenterol. 14, 5641-5649 (2008).
-
(2008)
World J. Gastroenterol
, vol.14
, pp. 5641-5649
-
-
Esteller, A.1
-
4
-
-
0033470181
-
The good, the bad, and the ugly
-
A. F. Hofmann, Bile Acids: The Good, the Bad, and the Ugly. News Physiol Sci. 14, 24-29 (1999).
-
(1999)
News Physiol Sci
, vol.14
, pp. 24-29
-
-
Hofmann, A.F.1
Acids, B.2
-
5
-
-
0036256463
-
Mechanisms of hepatic transport of drugs: Implications for cholestatic drug reactions
-
DOI 10.1055/s-2002-30099
-
A. Bohan and J. L. Boyer: Mechanisms of hepatic transport of drugs: implications for cholestatic drug reactions. Semin. Liver Dis. 22, 123-136 (2002). (Pubitemid 34496466)
-
(2002)
Seminars in Liver Disease
, vol.22
, Issue.2
, pp. 123-136
-
-
Bohan, A.1
Boyer, J.L.2
-
6
-
-
0033736448
-
Hepatic transport of bile salts
-
G. A. Kullak-Ublick, B. Stieger, B. Hagenbuch, and P. J. Meier: Hepatic transport of bile salts. Semin. Liver Dis. 20, 273-292 (2000).
-
(2000)
Semin. Liver Dis
, vol.20
, pp. 273-292
-
-
Kullak-Ublick, G.A.1
Stieger, B.2
Hagenbuch, B.3
Meier, P.J.4
-
7
-
-
36849094413
-
Review article: The function and regulation of proteins involved in bile salt biosynthesis and transport
-
DOI 10.1111/j.1365-2036.2007.03522.x
-
A. Pellicoro and K. N. Faber: Review article: The function and regulation of proteins involved in bile salt biosynthesis and transport. Aliment. Pharmacol. Ther. 26 Suppl 2, 149-160 (2007). (Pubitemid 350233340)
-
(2007)
Alimentary Pharmacology and Therapeutics
, vol.26
, Issue.SUPPL. 2
, pp. 149-160
-
-
Pellicoro, A.1
Faber, K.N.2
-
8
-
-
25144450046
-
Apical/basolateral surface expression of drug transporters and its role in vectorial drug transport
-
DOI 10.1007/s11095-005-6810-2
-
K. Ito, H. Suzuki, T. Horie, and Y. Sugiyama: Apical/basolateral surface expression of drug transporters and its role in vectorial drug transport. Pharm. Res. 22, 1559-1577 (2005). (Pubitemid 41355896)
-
(2005)
Pharmaceutical Research
, vol.22
, Issue.10
, pp. 1559-1577
-
-
Ito, K.1
Suzuki, H.2
Horie, T.3
Sugiyama, Y.4
-
9
-
-
34548103493
-
Role of OATP transporters in the disposition of drugs
-
DOI 10.2217/14622416.8.7.787
-
M. Niemi, Role of OATP transporters in the disposition of drugs. Pharmacogenomics. 8, 787-802 (2007). (Pubitemid 47288978)
-
(2007)
Pharmacogenomics
, vol.8
, Issue.7
, pp. 787-802
-
-
Niemi, M.1
-
10
-
-
0030753125
-
Molecular aspects of hepatobiliary transport
-
M. Muller and P. L. Jansen: Molecular aspects of hepatobiliary transport. Am J Physiol 272, G1285-G1303 (1997).
-
(1997)
Am J Physiol
, vol.272
-
-
Muller, M.1
Jansen, P.L.2
-
11
-
-
0037379362
-
Bile salt transporters: Molecular characterization, function, and regulation
-
M. Trauner and J. L. Boyer: Bile salt transporters: molecular characterization, function, and regulation. Physiol Rev. 83, 633-671 (2003). (Pubitemid 36378680)
-
(2003)
Physiological Reviews
, vol.83
, Issue.2
, pp. 633-671
-
-
Trauner, M.1
Boyer, J.L.2
-
12
-
-
0034968246
-
Comparison of "type I" and "type II" organic cation transport by organic cation transporters and organic anion-transporting polypeptides
-
J. E. van Montfoort, M. Muller, G. M. Groothuis, D. K. Meijer, H. Koepsell, and P. J. Meier: Comparison of "type I" and "type II" organic cation transport by organic cation transporters and organic anion-transporting polypeptides. J. Pharmacol. Exp. Ther. 298, 110-115 (2001). (Pubitemid 32574516)
-
(2001)
Journal of Pharmacology and Experimental Therapeutics
, vol.298
, Issue.1
, pp. 110-115
-
-
Van Montfoort, J.E.1
Muller, M.2
Groothuis, G.M.M.3
Meijer, D.K.F.4
Koepsell, H.5
Meier, P.J.6
-
13
-
-
0034604611
-
+ -coupled glutamine transporter
-
DOI 10.1074/jbc.M002282200
-
Y. J. Fei, M. Sugawara, T. Nakanishi, W. Huang, H. Wang, P. D. Prasad, F. H. Leibach, and V. Ganapathy: Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter. J. Biol. Chem. 275, 23707-23717 (2000). (Pubitemid 30624656)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.31
, pp. 23707-23717
-
-
Fei, Y.-J.1
Sugawara, M.2
Nakanishi, T.3
Huang, W.4
Wang, H.5
Prasad, P.D.6
Leibach, F.H.7
Ganapathy, V.8
-
14
-
-
0030778079
-
Hepatic secretion of phospholipid vesicles in the mouse critically depends on mdr2 or MDR3 P-glycoprotein expression: Visualization by electron microscopy
-
A. R. Crawford, A. J. Smith, V. C. Hatch, R. P. Oude Elferink, P. Borst, and J. M. Crawford: Hepatic secretion of phospholipid vesicles in the mouse critically depends on mdr2 or MDR3 P-glycoprotein expression. Visualization by electron microscopy. J Clin Invest 100, 2562-2567 (1997). (Pubitemid 27514896)
-
(1997)
Journal of Clinical Investigation
, vol.100
, Issue.10
, pp. 2562-2567
-
-
Crawford, A.R.1
Smith, A.J.2
Hatch, V.C.3
Oude Elferink, R.P.J.4
Borst, P.5
Crawford, J.M.6
-
15
-
-
0036733732
-
Biliary cholesterol secretion by the twinned sterol half-transporters ABCG5 and ABCG8
-
DOI 10.1172/JCI200216548
-
H. Wittenburg and M. C. Carey: Biliary cholesterol secretion by the twinned sterol half-transporters ABCG5 and ABCG8. J. Clin. Invest 110, 605-609 (2002). (Pubitemid 34988782)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.5
, pp. 605-609
-
-
Wittenburg, H.1
Carey, M.C.2
-
16
-
-
33745738902
-
Bile salt excretory pump: Biology and pathobiology
-
DOI 10.1097/01.mpg.0000226385.71859.5f, PII 0000517620060700100003
-
F. J. Suchy and M. Ananthanarayanan: Bile salt excretory pump: biology and pathobiology. J. Pediatr. Gastroenterol. Nutr. 43 Suppl 1, S10-S16 (2006). (Pubitemid 44014972)
-
(2006)
Journal of Pediatric Gastroenterology and Nutrition
, vol.43
, Issue.1 SUPPL. 1
-
-
Suchy, F.J.1
Ananthanarayanan, M.2
-
17
-
-
0035831094
-
Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump
-
DOI 10.1016/S0005-2736(00)00355-2, PII S0005273600003552
-
H. Akita, H. Suzuki, K. Ito, S. Kinoshita, N. Sato, H. Takikawa, and Y. Sugiyama: Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump. Biochim. Biophys. Acta 1511, 7-16 (2001). (Pubitemid 32206667)
-
(2001)
Biochimica et Biophysica Acta - Biomembranes
, vol.1511
, Issue.1
, pp. 7-16
-
-
Akita, H.1
Suzuki, H.2
Ito, K.3
Kinoshita, S.4
Sato, N.5
Takikawa, H.6
Sugiyama, Y.7
-
18
-
-
0033104810
-
Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione
-
C. C. Paulusma, M. A. van Geer, R. Evers, M. Heijn, R. Ottenhoff, P. Borst, and R. P. Oude Elferink: Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione. Biochem J 338 ( Pt 2), 393-401 (1999).
-
(1999)
Biochem J
, vol.338
, Issue.PART 2
, pp. 393-401
-
-
Paulusma, C.C.1
Van Geer, M.A.2
Evers, R.3
Heijn, M.4
Ottenhoff, R.5
Borst, P.6
Oude Elferink, R.P.7
-
19
-
-
0034803328
-
Nifedipine modulation of biliary GSH and GSSG/conjugate efflux in normal and regenerating rat liver
-
B. Yang and C. E. Hill: Nifedipine modulation of biliary GSH and GSSG/conjugate efflux in normal and regenerating rat liver. Am J Physiol 281, G85-G94 (2001).
-
(2001)
Am J Physiol
, vol.281
-
-
Yang, B.1
Hill, C.E.2
-
20
-
-
0026497882
-
Glutathione as a primary osmotic driving force in hepatic bile formation
-
N. Ballatori and A. T. Truong: Glutathione as a primary osmotic driving force in hepatic bile formation. Am J Physiol 263, G617-G624 (1992).
-
(1992)
Am J Physiol
, vol.263
-
-
Ballatori, N.1
Truong, A.T.2
-
21
-
-
33745698666
-
Cholangiocyte anion exchange and biliary bicarbonate excretion
-
J. M. Banales, J. Prieto, and J. F. Medina: Cholangiocyte anion exchange and biliary bicarbonate excretion. World J. Gastroenterol. 12, 3496-3511 (2006). (Pubitemid 43997027)
-
(2006)
World Journal of Gastroenterology
, vol.12
, Issue.22
, pp. 3496-3511
-
-
Banales, J.M.1
Prieto, J.2
Medina, J.F.3
-
23
-
-
0034614467
-
Tissue-specific N-terminal isoforms from overlapping alternate promoters of the human AE2 anion exchanger gene
-
DOI 10.1006/bbrc.1999.1951
-
J. F. Medina, J. Lecanda, A. Acin, P. Ciesielczyk, and J. Prieto: Tissue-specific N-terminal isoforms from overlapping alternate promoters of the human AE2 anion exchanger gene. Biochem. Biophys. Res. Commun. 267, 228-235 (2000). (Pubitemid 30072535)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.267
, Issue.1
, pp. 228-235
-
-
Medina, J.F.1
Lecanda, J.2
Acin, A.3
Ciesielczyk, P.4
Prieto, J.5
-
24
-
-
2942596086
-
2 in primary hepatocytes
-
DOI 10.1016/j.bbrc.2004.05.080, PII S0006291X04010575
-
V. Aranda, I. Martinez, S. Melero, J. Lecanda, J. M. Banales, J. Prieto, and J. F. Medina: Shared apical sorting of anion exchanger isoforms AE2a, AE2b1, and AE2b2 in primary hepatocytes. Biochem. Biophys. Res. Commun. 319, 1040-1046 (2004). (Pubitemid 38739424)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.319
, Issue.3
, pp. 1040-1046
-
-
Aranda, V.1
Martinez, I.2
Melero, S.3
Lecanda, J.4
Banales, J.M.5
Prieto, J.6
Medina, J.F.7
-
25
-
-
0037151071
-
Expression and localization of aquaporin water channels in rat hepatocytes. Evidence for a role in canalicular bile secretion
-
DOI 10.1074/jbc.M202394200
-
R. C. Huebert, P. L. Splinter, F. Garcia, R. A. Marinelli, and N. F. LaRusso: Expression and localization of aquaporin water channels in rat hepatocytes. Evidence for a role in canalicular bile secretion. J Biol Chem 277, 22710- 22717 (2002). (Pubitemid 34967250)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.25
, pp. 22710-22717
-
-
Huebert, R.C.1
Splinter, P.L.2
Garcia, F.3
Marinelli, R.A.4
Larusso, N.F.5
-
26
-
-
0035853805
-
The water channel aquaporin-8 is mainly intracellular in rat hepatocytes, and its plasma membrane insertion is stimulated by cyclic AMP
-
F. Garcia, A. Kierbel, M. C. Larocca, S. A. Gradilone, P. Splinter, N. F. LaRusso, and R. A. Marinelli: The water channel aquaporin-8 is mainly intracellular in rat hepatocytes, and its plasma membrane insertion is stimulated by cyclic AMP. J Biol Chem 276, 12147-12152 (2001).
-
(2001)
J Biol Chem
, vol.276
, pp. 12147-12152
-
-
Garcia, F.1
Kierbel, A.2
Larocca, M.C.3
Gradilone, S.A.4
Splinter, P.5
Larusso, N.F.6
Marinelli, R.A.7
-
27
-
-
13844309817
-
Liver aquaporins: Significance in canalicular and ductal bile formation
-
R. A. Marinelli, S. A. Gradilone, F. I. Carreras, G. Calamita, and G. L. Lehmann: Liver aquaporins: significance in canalicular and ductal bile formation. Ann. Hepatol. 3, 130-136 (2004).
-
(2004)
Ann. Hepatol.
, vol.3
, pp. 130-136
-
-
Marinelli, R.A.1
Gradilone, S.A.2
Carreras, F.I.3
Calamita, G.4
Lehmann, G.L.5
-
28
-
-
58249120675
-
Knockdown of hepatocyte aquaporin-8 by RNA interference induces defective bile canalicular water transport
-
M. C. Larocca, L. R. Soria, M. V. Espelt, G. L. Lehmann, and R. A. Marinelli: Knockdown of hepatocyte aquaporin-8 by RNA interference induces defective bile canalicular water transport. Am. J. Physiol Gastrointest. Liver Physiol 296, G93-100 (2009).
-
(2009)
Am. J. Physiol Gastrointest, Liver Physiol
, vol.296
-
-
Larocca, M.C.1
Soria, L.R.2
Espelt, M.V.3
Lehmann, G.L.4
Marinelli, R.A.5
-
29
-
-
0036614376
-
Altered localization and activity of canalicular Mrp2 in estradiol-17β-D-glucuronide-induced cholestasis
-
DOI 10.1053/jhep.2002.33327
-
A. D. Mottino, J. Cao, L. M. Veggi, F. A. Crocenzi, M. G. Roma, and M. Vore: Altered localization and activity of canalicular Mrp2 in estradiol-17β-D-glucuronide-induced cholestasis. Hepatology 35, 1409-1419 (2002). (Pubitemid 34966895)
-
(2002)
Hepatology
, vol.35
, Issue.6
, pp. 1409-1419
-
-
Mottino, A.D.1
Cao, J.2
Veggi, L.M.3
Crocenzi, F.4
Roma, M.G.5
Vore, M.6
-
30
-
-
0038102818
-
Estradiol-17β-D-glucuronide induces endocytic internalization of Bsep in rats
-
F. A. Crocenzi, A. D. Mottino, J. Cao, L. M. Veggi, E. J. Sanchez Pozzi, M. Vore, R. Coleman, and M. G. Roma: Estradiol-17-βD-glucuronide induces endocytic internalization of Bsep in rats. Am J Physiol Gastrointest Liver Physiol 285, G449-G459 (2003). (Pubitemid 36875218)
-
(2003)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.285
, Issue.2
-
-
Crocenzi, F.A.1
Mottino, A.D.2
Cao, J.3
Veggi, L.M.4
Sanchez Pozzi, E.J.5
Vore, M.6
Coleman, R.7
Roma, M.G.8
-
31
-
-
0035038177
-
Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver
-
DOI 10.1053/jhep.2001.24034
-
U. Beuers, M. Bilzer, A. Chittattu, G. A. Kullak- Ublick, D. Keppler, G. Paumgartner, and F. Dombrowski: Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase Cdependent mechanisms in cholestatic rat liver. Hepatology 33, 1206-1216 (2001). (Pubitemid 32378221)
-
(2001)
Hepatology
, vol.33
, Issue.5
, pp. 1206-1216
-
-
Beuers, U.1
Bilzer, M.2
Chittattu, A.3
Kullak-Ublick, G.A.4
Keppler, D.5
Paumgartner, G.6
Dombrowski, F.7
-
32
-
-
0037483657
-
Impaired localisation and transport function of canalicular Bsep in taurolithocholate induced cholestasis in the rat
-
DOI 10.1136/gut.52.8.1170
-
F. A. Crocenzi, A. D. Mottino, E. J. Sanchez Pozzi, J. M. Pellegrino, E. A. Rodríguez Garay, P. Milkiewicz, M. Vore, R. Coleman, and M. G. Roma: Impaired localisation and transport function of canalicular Bsep in taurolithocholate-induced cholestasis in the rat. Gut 52, 1170-1177 (2003). (Pubitemid 36877431)
-
(2003)
Gut
, vol.52
, Issue.8
, pp. 1170-1177
-
-
Crocenzi, F.A.1
Mottino, A.D.2
Sanchez Pozzi, E.J.3
Pellegrino, J.M.4
Rodriguez Garay, E.A.5
Milkiewicz, P.6
Vore, M.7
Coleman, R.8
Roma, M.G.9
-
33
-
-
17144473982
-
Cyclosporin A induced internalization of the bile salt export pump in isolated rat hepatocyte couplets
-
DOI 10.1093/toxsci/71.2.276
-
I. D. Roman, M. D. Fernandez-Moreno, J. A. Fueyo, M. G. Roma, and R. Coleman: Cyclosporin A induced internalization of the bile salt export pump in isolated rat hepatocyte couplets. Toxicol Sci 71, 276-281 (2003). (Pubitemid 36285019)
-
(2003)
Toxicological Sciences
, vol.71
, Issue.2
, pp. 276-281
-
-
Roman, I.D.1
Fernandez-Moreno, M.D.2
Fueyo, J.A.3
Roma, M.G.4
Coleman, R.5
-
34
-
-
0017395169
-
Taurolithocholate inhibits taurocholate uptake by isolated hepatocytes at low concentrations
-
M. Schwenk, L. R. Schwarz, and H. Greim: Taurolithocholate inhibits taurocholate uptake by isolated hepatocytes at low concentrations. Naunyn Schmiedebergs Arch. Pharmacol. 298, 175-179 (1977). (Pubitemid 8123968)
-
(1977)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.298
, Issue.2
, pp. 175-179
-
-
Schwenk, M.1
Schwarz, L.R.2
Greim, H.3
-
35
-
-
72749104610
-
PKC{epsilon}- dependent and -independent effects of taurolithocholate on PI3K/PKB pathway and taurocholate uptake in HuH-NTCP cell line
-
C. M. Schonhoff, A. Yamazaki, S. Hohenester, C. R. Webster, B. Bouscarel, and M. S. Anwer: PKC{epsilon}- dependent and -independent effects of taurolithocholate on PI3K/PKB pathway and taurocholate uptake in HuH-NTCP cell line. Am. J. Physiol Gastrointest. Liver Physiol 297, G1259-G1267 (2009).
-
(2009)
Am. J. Physiol Gastrointest, Liver Physiol
, vol.297
-
-
Schonhoff, C.M.1
Yamazaki, A.2
Hohenester, S.3
Webster, C.R.4
Bouscarel, B.5
Anwer, M.S.6
-
36
-
-
0018932302
-
Characterization of cholestasis induced by estradiol-17β-D- glucuronide in the rat
-
M. Meyers, W. Slikker, G. Pascoe, and M. Vore: Characterization of cholestasis induced by estradiol-17 beta-D-glucuronide in the rat. J. Pharmacol. Exp. Ther. 214, 87-93 (1980). (Pubitemid 10032387)
-
(1980)
Journal of Pharmacology and Experimental Therapeutics
, vol.214
, Issue.1
, pp. 87-93
-
-
Meyers, M.1
Slikker, W.2
Pascoe, G.3
Vore, M.4
-
37
-
-
12344252793
-
Role of microtubules in estradiol-17β-D-glucuronide-induced alteration of canalicular Mrp2 localization and activity
-
DOI 10.1152/ajpgi.00227.2004
-
A. D. Mottino, F. A. Crocenzi, E. J. Pozzi, L. M. Veggi, M. G. Roma, and M. Vore: Role of microtubules in estradiol-17beta-D-glucuronide-induced alteration of canalicular Mrp2 localization and activity. Am J Physiol Gastrointest. Liver Physiol 288, G327-G336 (2005). (Pubitemid 40129585)
-
(2005)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.288
, Issue.2
-
-
Mottino, A.D.1
Crocenzi, F.A.2
Sanchez Pozzi, E.J.3
Veggi, L.M.4
Roma, M.G.5
Vore, M.6
-
38
-
-
34547138186
-
Disruption of function and localization of tight junctional structures and Mrp2 in sustained estradiol-17β-D-glucuronide-induced cholestasis
-
DOI 10.1152/ajpgi.00496.2006
-
A. D. Mottino, T. Hoffman, F. A. Crocenzi, E. J. Sanchez Pozzi, M. G. Roma, and M. Vore: Disruption of function and localization of tight junctional structures and Mrp2 in sustained estradiol-17beta-D-glucuronide-induced cholestasis. Am. J. Physiol Gastrointest. Liver Physiol 293, G391-G402 (2007). (Pubitemid 47105200)
-
(2007)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.293
, Issue.1
-
-
Mottino, A.D.1
Hoffman, T.2
Crocenzi, F.A.3
Sanchez Pozzi, E.J.4
Roma, M.G.5
Vore, M.6
-
39
-
-
0024351792
-
Oestradiol 17β-glucuronide increases tight-junctional permeability in rat liver
-
K. S. Kan, M. Monte, R. A. Parslow, and R. Coleman: Oestradiol 17β-glucuronide increases tight junctional permeability in rat liver. Biochem J 261, 297-300 (1989). (Pubitemid 19174795)
-
(1989)
Biochemical Journal
, vol.261
, Issue.1
, pp. 297-300
-
-
Kan, K.S.1
Monte, M.J.2
Parslow, R.A.3
Coleman, R.4
-
40
-
-
0027234009
-
Liver damage due to free radicals
-
G. Poli, Liver damage due to free radicals. Br. Med Bull. 49, 604-620 (1993). (Pubitemid 23243833)
-
(1993)
British Medical Bulletin
, vol.49
, Issue.3
, pp. 604-620
-
-
Poli, G.1
-
41
-
-
41549129374
-
Oxidative stress: A radical way to stop making bile
-
M. G. Roma and E. J. Sanchez Pozzi: Oxidative stress: a radical way to stop making bile. Ann. Hepatol. 7, 16-33 (2008). (Pubitemid 351468534)
-
(2008)
Annals of Hepatology
, vol.7
, Issue.1
, pp. 16-33
-
-
Roma, M.G.1
Sanchez Pozzi, E.J.2
-
42
-
-
33645810797
-
Oxidative stress induces internalization of the bile salt export pump, Bsep, and bile salt secretory failure in isolated rat hepatocyte couplets: A role for protein kinase C and prevention by protein kinase A
-
L. M. Perez, P. Milkiewicz, E. Elias, R. Coleman, E. J. Sanchez Pozzi, and M. G. Roma: Oxidative stress induces internalization of the bile salt export pump, Bsep, and bile salt secretory failure in isolated rat hepatocyte couplets: a role for protein kinase C and prevention by protein kinase A. Toxicol. Sci. 91, 150-158 (2006).
-
(2006)
Toxicol. Sci.
, vol.91
, pp. 150-158
-
-
Perez, L.M.1
Milkiewicz, P.2
Elias, E.3
Coleman, R.4
Pozzi, E.J.S.5
Roma, M.G.6
-
43
-
-
0033947842
-
Retrieval of the mrp2 gene encoded conjugate export pump from the canalicular membrane contributes to cholestasis induced by tert-Butyl hydroperoxide and chloro-dinitrobenzene
-
M. Schmitt, R. Kubitz, M. Wettstein, S. vom Dahl, and D. Haussinger: Retrieval of the mrp2 gene encoded conjugate export pump from the canalicular membrane contributes to cholestasis induced by tert-butyl hydroperoxide and chloro-dinitrobenzene. Biol. Chem 381, 487-495 (2000). (Pubitemid 30453827)
-
(2000)
Biological Chemistry
, vol.381
, Issue.5-6
, pp. 487-495
-
-
Schmitt, M.1
Kubitz, R.2
Wettstein, M.3
Vom Dahl, S.4
Haussinger, D.5
-
44
-
-
7444234246
-
Ethacrynic-acid-induced glutathione depletion and oxidative stress in normal and Mrp2-deficient rat liver
-
DOI 10.1016/j.freeradbiomed.2004.08.020, PII S0891584904006811
-
B. Ji, K. Ito, S. Sekine, A. Tajima, and T. Horie: Ethacrynic-acid- induced glutathione depletion and oxidative stress in normal and Mrp2-deficient rat liver. Free Radic. Biol. Med. 37, 1718-1729 (2004). (Pubitemid 39441056)
-
(2004)
Free Radical Biology and Medicine
, vol.37
, Issue.11
, pp. 1718-1729
-
-
Ji, B.1
Ito, K.2
Sekine, S.3
Tajima, A.4
Horie, T.5
-
45
-
-
33745165982
-
Oxidative stress and Mrp2 internalization
-
DOI 10.1016/j.freeradbiomed.2006.02.015, PII S0891584906001250
-
S. Sekine, K. Ito, and T. Horie: Oxidative stress and Mrp2 internalization. Free Radic. Biol. Med. 40, 2166-2174 (2006). (Pubitemid 43903103)
-
(2006)
Free Radical Biology and Medicine
, vol.40
, Issue.12
, pp. 2166-2174
-
-
Sekine, S.1
Ito, K.2
Horie, T.3
-
46
-
-
1842584562
-
Kupffer cells alter organic anion transport through multidrug resistance protein 2 in the post-cold ischemic rat liver
-
DOI 10.1002/hep.20104
-
A. Kudo, S. Kashiwagi, M. Kajimura, Y. Yoshimura, K. Uchida, S. Arii, and M. Suematsu: Kupffer cells alter organic anion transport through multidrug resistance protein 2 in the post-cold ischemic rat liver. Hepatology 39, 1099-1109 (2004). (Pubitemid 38428949)
-
(2004)
Hepatology
, vol.39
, Issue.4
, pp. 1099-1109
-
-
Rudo, A.1
Kashiwagi, S.2
Kajimura, M.3
Yoshimura, Y.4
Uchida, K.5
Arii, S.6
Suematsu, M.7
-
47
-
-
64849099982
-
Decreased Mrp2-dependent bile flow in the post-warm ischemic rat liver
-
D. Ban, A. Kudo, S. Sui, S. Tanaka, N. Nakamura, K. Ito, M. Suematsu, and S. Arii: Decreased Mrp2-dependent bile flow in the post-warm ischemic rat liver. J. Surg. Res. 153, 310-316 (2009).
-
(2009)
J. Surg. Res.
, vol.153
, pp. 310-316
-
-
Ban, D.1
Kudo, A.2
Sui, S.3
Tanaka, S.4
Nakamura, N.5
Ito, K.6
Suematsu, M.7
Arii, S.8
-
48
-
-
57349165780
-
Canalicular Mrp2 localization is reversibly regulated by the intracellular redox status
-
S. Sekine, K. Ito, and T. Horie: Canalicular Mrp2 localization is reversibly regulated by the intracellular redox status. Am. J. Physiol Gastrointest. Liver Physiol 295, G1035-G1041 (2008).
-
(2008)
Am. J. Physiol Gastrointest, Liver Physiol
, vol.295
-
-
Sekine, S.1
Ito, K.2
Horie, T.3
-
49
-
-
33846426043
-
Sepsis-induced cholestasis
-
DOI 10.1002/hep.21480
-
N. Chand and A. J. Sanyal: Sepsis-induced cholestasis. Hepatology 45, 230-241 (2007). (Pubitemid 46144383)
-
(2007)
Hepatology
, vol.45
, Issue.1
, pp. 230-241
-
-
Chand, N.1
Sanyal, A.J.2
-
50
-
-
33749356605
-
Mechanisms of disease: Mechanisms and clinical implications of cholestasis in sepsis
-
DOI 10.1038/ncpgasthep0602, PII NCPGASTHEP0602
-
A. Geier, P. Fickert, and M. Trauner: Mechanisms of disease: mechanisms and clinical implications of cholestasis in sepsis. Nat. Clin. Pract. Gastroenterol. Hepatol. 3, 574-585 (2006). (Pubitemid 44489590)
-
(2006)
Nature Clinical Practice Gastroenterology and Hepatology
, vol.3
, Issue.10
, pp. 574-585
-
-
Geier, A.1
Fickert, P.2
Trauner, M.3
-
51
-
-
0346100571
-
Enterohepatic bile salt transporters in normal physiology and liver disease
-
DOI 10.1053/j.gastro.2003.06.005
-
G. A. Kullak-Ublick, B. Stieger, and P. J. Meier: Enterohepatic bile salt transporters in normal physiology and liver disease. Gastroenterology 126, 322-342 (2004). (Pubitemid 38040747)
-
(2004)
Gastroenterology
, vol.126
, Issue.1 SUPPL. 1
, pp. 322-342
-
-
Kullak-Ublick, G.A.1
Stieger, B.2
Meier, P.J.3
-
52
-
-
0034657167
-
Electron-microscopic demonstration of multidrug resistance protein 2 (Mrp2) retrieval from the canalicular membrane in response to hyperosmolarity and lipopolysaccharide
-
DOI 10.1042/0264-6021:3480183
-
F. Dombrowski, R. Kubitz, A. Chittattu, M. Wettstein, N. Saha, and D. Haussinger: Electromicroscopic demonstration of multidrug resistance protein 2 (Mrp2) retrieval from the canalicular membrane in response to hyperosmolarity and lipopolysaccharide. Biochem J 348, 183-188 (2000). (Pubitemid 30312147)
-
(2000)
Biochemical Journal
, vol.348
, Issue.1
, pp. 183-188
-
-
Dombrowski, F.1
Kubitz, R.2
Chittattu, A.3
Wettstein, M.4
Saha, N.5
Haussinger, D.6
-
53
-
-
0032944048
-
Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone
-
DOI 10.1016/S0016-5085(99)70138-1
-
R. Kubitz, M. Wettstein, U. Warskulat, and D. Häussinger: Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone. Gastroenterology 116, 401-410 (1999). (Pubitemid 29055364)
-
(1999)
Gastroenterology
, vol.116
, Issue.2
, pp. 401-410
-
-
Kubitz, R.1
Wettstein, M.2
Warskulat, U.3
Haussinger, D.4
-
54
-
-
7044223146
-
LPS-induced downreguiation of MRP2 and BSEP in human liver is due to a posttranscriptional process
-
DOI 10.1152/ajpgi.00071.2004
-
M. G. Elferink, P. Olinga, A. L. Draaisma, M. T. Merema, K. N. Faber, M. J. Slooff, D. K. Meijer, and G. M. Groothuis: LPS-induced downregulation of MRP2 and BSEP in human liver is due to a posttranscriptional process. Am. J. Physiol Gastrointest. Liver Physiol 287, G1008- G1016 (2004). (Pubitemid 39423693)
-
(2004)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.287
, Issue.5
-
-
Elferink, M.G.L.1
Olinga, P.2
Draaisma, A.L.3
Merema, M.T.4
Faber, K.N.5
Slooff, M.J.H.6
Meijer, D.K.F.7
Groothuis, G.M.M.8
-
55
-
-
0031738416
-
Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver
-
T. A. Vos, G. J. E. J. Hooiveld, H. Koning, S. Childs, D. K. F. Meijer, H. Moshage, P. L. Jansen, and M. Muller: Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver. Hepatology 28, 1637-1644 (1998). (Pubitemid 28549135)
-
(1998)
Hepatology
, vol.28
, Issue.6
, pp. 1637-1644
-
-
Vos, T.A.1
Hooiveld, G.J.E.J.2
Koning, H.3
Childs, S.4
Meijer, D.K.F.5
Moshage, H.6
Jansen, P.L.M.7
Muller, M.8
-
56
-
-
23744470316
-
Experimental LPS-induced cholestasis alters subcellular distribution and affects colocalization of Mrp2 and Bsep proteins: A quantitative colocalization study
-
DOI 10.1002/jemt.20184
-
V. Zinchuk, O. Zinchuk, and T. Okada: Experimental LPS-induced cholestasis alters subcellular distribution and affects colocalization of Mrp2 and Bsep proteins: a quantitative colocalization study. Microsc. Res. Tech. 67, 65-70 (2005). (Pubitemid 41129255)
-
(2005)
Microscopy Research and Technique
, vol.67
, Issue.2
, pp. 65-70
-
-
Zinchuk, V.1
Zinchuk, O.2
Okada, T.3
-
57
-
-
0035124048
-
Regulation of the dynamic localization of the rat Bsep gene-encoded bile salt export pump by anisoosmolarity
-
DOI 10.1053/jhep.2001.22648
-
M. Schmitt, R. Kubitz, S. Lizun, M. Wettstein, and D. Haussinger: Regulation of the dynamic localization of the rat Bsep gene-encoded bile salt export pump by anisoosmolarity. Hepatology 33, 509-518 (2001). (Pubitemid 32185211)
-
(2001)
Hepatology
, vol.33
, Issue.3
, pp. 509-518
-
-
Schmitt, M.1
Kubitz, R.2
Lizun, S.3
Wettstein, M.4
Haussinger, D.5
-
58
-
-
0036210277
-
Heat stress prevents impairment of bile acid transport in endotoxemic rats by a posttranscriptional mechanism
-
U. Bolder, A. Schmidt, L. Landmann, V. Kidder, S. Tange, and K. W. Jauch: Heat stress prevents impairment of bile acid transport in endotoxemic rats by a posttranscriptional mechanism. Gastroenterology 122, 963-973 (2002). (Pubitemid 34267280)
-
(2002)
Gastroenterology
, vol.122
, Issue.4
, pp. 963-973
-
-
Bolder, U.1
Schmidt, A.2
Landmann, L.3
Kidder, V.4
Tange, S.5
Jauch, K.6
-
59
-
-
33644839511
-
Heat stress enhances recovery of hepatocyte bile acid and organic anion transporters in endotoxemic rats by multiple mechanisms
-
DOI 10.1379/CSC-143R.1
-
U. Bolder, M. G. Jeschke, L. Landmann, F. Wolf, S. C. de, H. J. Schlitt, and R. Przkora: Heat stress enhances recovery of hepatocyte bile acid and organic anion transporters in endotoxemic rats by multiple mechanisms. Cell Stress. Chaperones. 11, 89-100 (2006). (Pubitemid 43363829)
-
(2006)
Cell Stress and Chaperones
, vol.11
, Issue.1
, pp. 89-100
-
-
Bolder, U.1
Jeschke, M.G.2
Landmann, L.3
Wolf, F.4
De Sousa, C.5
Schlitt, H.-J.6
Przkora, R.7
-
60
-
-
0029886277
-
Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents
-
DOI 10.1053/gast.1996.v111.pm8698199
-
R. M. Green, D. Beier, and J. L. Gollan: Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents. Gastroenterology 111, 193-198 (1996). (Pubitemid 26226899)
-
(1996)
Gastroenterology
, vol.111
, Issue.1
, pp. 193-198
-
-
Green, R.M.1
Beier, D.2
Gollan, J.L.3
-
61
-
-
0039849217
-
Intraabdominal sepsis down-regulates transcription of sodium taurocholate cotransporter and multidrug resistance-associated protein in rats
-
P. K. Kim, J. Chen, K. M. Andrejko, and C. S. Deutschman: Intraabdominal sepsis down-regulates transcription of sodium taurocholate cotransporter and multidrug resistance-associated protein in rats. Shock 14, 176-181 (2000).
-
(2000)
Shock
, vol.14
, pp. 176-181
-
-
Kim, P.K.1
Chen, J.2
Andrejko, K.M.3
Deutschman, C.S.4
-
62
-
-
4143070233
-
Interleukin-6 regulates hepatic transporters during acute-phase response
-
DOI 10.1016/j.bbrc.2004.07.102, PII S0006291X0401616X
-
E. Siewert, C. G. Dietrich, F. Lammert, P. C. Heinrich, S. Matern, C. Gartung, and A. Geier: Interleukin-6 regulates hepatic transporters during acute-phase response. Biochem. Biophys. Res. Commun. 322, 232-238 (2004). (Pubitemid 39093860)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.322
, Issue.1
, pp. 232-238
-
-
Siewert, E.1
Dietrich, C.G.2
Lammert, F.3
Heinrich, P.C.4
Matern, S.5
Gartung, C.6
Geier, A.7
-
63
-
-
0028580429
-
Interleukin-6 inhibits hepatocyte taurocholate uptake and sodium-potassiumadenosinetriphosphatase activity
-
R. M. Green, J. F. Whiting, A. B. Rosenbluth, D. Beier, and J. L. Gollan: Interleukin-6 inhibits hepatocyte taurocholate uptake and sodium- potassiumadenosinetriphosphatase activity. Am. J. Physiol 267, G1094-G1100 (1994).
-
(1994)
Am. J. Physiol.
, vol.267
-
-
Green, R.M.1
Whiting, J.F.2
Rosenbluth, A.B.3
Beier, D.4
Gollan, J.L.5
-
64
-
-
0029120107
-
Tumor necrosis factor-alpha decreases hepatocyte bile salt uptake and mediates endotoxininduced cholestasis
-
J. F. Whiting, R. M. Green, A. B. Rosenbluth, and J. L. Gollan: Tumor necrosis factor-alpha decreases hepatocyte bile salt uptake and mediates endotoxininduced cholestasis. Hepatology 22, 1273-1278 (1995).
-
(1995)
Hepatology
, vol.22
, pp. 1273-1278
-
-
Whiting, J.F.1
Green, R.M.2
Rosenbluth, A.B.3
Gollan, J.L.4
-
66
-
-
77953912527
-
The effect of dimerumic acid on LPS-induced downregulation of Mrp2 in the rat
-
K. Yano, S. Sekine, K. Nemoto, T. Fuwa, and T. Horie: The effect of dimerumic acid on LPS-induced downregulation of Mrp2 in the rat. Biochem. Pharmacol. 80, 533-539 (2010).
-
(2010)
Biochem. Pharmacol
, vol.80
, pp. 533-539
-
-
Yano, K.1
Sekine, S.2
Nemoto, K.3
Fuwa, T.4
Horie, T.5
-
67
-
-
77955841114
-
Oxidative stress is a triggering factor for LPS-induced Mrp2 internalization in the cryopreserved rat and human liver slices
-
S. Sekine, K. Yano, J. Saeki, N. Hashimoto, T. Fuwa, and T. Horie: Oxidative stress is a triggering factor for LPS-induced Mrp2 internalization in the cryopreserved rat and human liver slices. Biochem. Biophys. Res. Commun. 399, 279-285 (2010).
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.399
, pp. 279-285
-
-
Sekine, S.1
Yano, K.2
Saeki, J.3
Hashimoto, N.4
Fuwa, T.5
Horie, T.6
-
68
-
-
17544372167
-
Zonal down-regulation and redistribution of the multidrug resistance protein 2 during bile duct ligation in rat liver
-
C. C. Paulusma, M. J. Kothe, C. T. Bakker, P. J. Bosma, B. van, I, J. van Marle, U. Bolder, G. N. Tytgat, and R. P. Oude Elferink: Zonal down-regulation and redistribution of the multidrug resistance protein 2 during bile duct ligation in rat liver. Hepatology 31, 684-693 (2000). (Pubitemid 30118637)
-
(2000)
Hepatology
, vol.31
, Issue.3
, pp. 684-693
-
-
Paulusma, C.C.1
Christine Kothe, M.J.2
Bakker, C.T.M.3
Bosma, P.J.4
Van Bokhoven, I.5
Van Marle, J.6
Bolder, U.7
Tytgat, G.N.J.8
Oude Elferink, R.P.J.9
-
69
-
-
0029658190
-
2+-ATPase activity in relation to alterations of the cytoskeleton and tight junctions in hepatocytes of cholestatic rat liver
-
J. Y. Song, M. J. Van, C. J. Van Noorden, and W. F. Frederiks: Redistribution of Ca2+, Mg2+-ATPase activity in relation to alterations of the cytoskeleton and tight junctions in hepatocytes of cholestatic rat liver. Eur. J. Cell Biol. 71, 277-285 (1996). (Pubitemid 26388423)
-
(1996)
European Journal of Cell Biology
, vol.71
, Issue.3
, pp. 277-285
-
-
Song, J.-Y.1
Van Marle, J.2
Van Noorden, C.J.F.3
Frederiks, W.F.4
-
70
-
-
42549096967
-
Hepatocellular transport in acquired cholestasis: New insights into functional, regulatory and therapeutic aspects
-
DOI 10.1042/CS20070227
-
M. G. Roma, F. A. Crocenzi, and E. A. Sanchez Pozzi: Hepatocellular transport in acquired cholestasis: new insights into functional, regulatory and therapeutic aspects. Clin. Sci. (Lond) 114, 567-588 (2008). (Pubitemid 351589057)
-
(2008)
Clinical Science
, vol.114
, Issue.9-10
, pp. 567-588
-
-
Roma, M.G.1
Crocenzi, F.A.2
Sanchez Pozzi, E.A.3
-
71
-
-
15444373825
-
Molecular regulation of hepatobiliary transport systems: Clinical implications for understanding and treating cholestasis
-
M. Trauner, M. Wagner, P. Fickert, and G. Zollner: Molecular regulation of hepatobiliary transport systems: clinical implications for understanding and treating cholestasis. J. Clin. Gastroenterol. 39, S111-S124 (2005). (Pubitemid 40397024)
-
(2005)
Journal of Clinical Gastroenterology
, vol.39
, Issue.4 SUPPL.
-
-
Trauner, M.1
Wagner, M.2
Fickert, P.3
Zollner, G.4
-
72
-
-
0030963906
-
The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis
-
DOI 10.1016/S0016-5085(97)70103-3
-
M. Trauner, M. Arrese, C. J. Soroka, M. Ananthanarayanan, T. A. Koeppel, S. F. Schlosser, F. J. Suchy, D. Keppler, and J. L. Boyer: The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis. Gastroenterology 113, 255-264 (1997). (Pubitemid 27281782)
-
(1997)
Gastroenterology
, vol.113
, Issue.1
, pp. 255-264
-
-
Trauner, M.1
Arrese, M.2
Soroka, C.J.3
Ananthanarayanan, M.4
Koeppel, T.A.5
Schlosser, S.F.6
Suchy, F.J.7
Keppler, D.8
Boyer, J.L.9
-
73
-
-
33644657346
-
Alteration of the expression of adenosine triphosphate-binding cassette transporters associated with bile acid and cholesterol transport in the rat liver and intestine during cholestasis
-
DOI 10.1111/j.1440-1746.2005.03950.x
-
T. Kamisako and H. Ogawa: Alteration of the expression of adenosine triphosphate-binding cassette transporters associated with bile acid and cholesterol transport in the rat liver and intestine during cholestasis. J. Gastroenterol. Hepatol. 20, 1429-1434 (2005). (Pubitemid 43960843)
-
(2005)
Journal of Gastroenterology and Hepatology
, vol.20
, Issue.9
, pp. 1429-1434
-
-
Kamisako, T.1
Ogawa, H.2
-
74
-
-
0043170767
-
Unique reciprocal changes of hepatocellular membrane transporter expression and fluidity in rats with selective biliary obstruction
-
DOI 10.1016/S1386-6346(03)00084-6
-
K. Kanno, S. Tazuma, S. Niida, and K. Chayama: Unique reciprocal changes of hepatocellular membrane transporter expression and fluidity in rats with selective biliary obstruction. Hepatol. Res. 26, 157-163 (2003). (Pubitemid 36927188)
-
(2003)
Hepatology Research
, vol.26
, Issue.2
, pp. 157-163
-
-
Kanno, K.1
Tazuma, S.2
Niida, S.3
Chayama, K.4
-
75
-
-
0033980287
-
Expression of the bile salt export pump is maintained after chronic cholestasis in the rat
-
J. M. Lee, M. Trauner, C. J. Soroka, B. Stieger, P. J. Meier, and J. L. Boyer: Expression of the bile salt export pump is maintained after chronic cholestasis in the rat. Gastroenterology 118, 163-172 (2000). (Pubitemid 30020384)
-
(2000)
Gastroenterology
, vol.118
, Issue.1
, pp. 163-172
-
-
Lee, J.M.1
Trauner, M.2
Soroka, C.J.3
Stieger, B.4
Meier, P.J.5
Boyer, J.L.6
-
76
-
-
33645128199
-
Early growth response factor-1 is critical for cholestatic liver injury
-
N. D. Kim, J. O. Moon, A. L. Slitt, and B. L. Copple: Early growth response factor-1 is critical for cholestatic liver injury. Toxicol. Sci. 90, 586-595 (2006).
-
(2006)
Toxicol. Sci.
, vol.90
, pp. 586-595
-
-
Kim, N.D.1
Moon, J.O.2
Slitt, A.L.3
Copple, B.L.4
-
77
-
-
49749096373
-
Retrieval of the rat canalicular conjugate export pump Mrp2 is associated with a rearrangement of actin filaments and radixin in bile salt-induced cholestasis
-
D. Rost, P. Kloeters-Plachky, and A. Stiehl: Retrieval of the rat canalicular conjugate export pump Mrp2 is associated with a rearrangement of actin filaments and radixin in bile salt-induced cholestasis. Eur. J. Med. Res. 13, 314-318 (2008).
-
(2008)
Eur. J. Med. Res.
, vol.13
, pp. 314-318
-
-
Rost, D.1
Kloeters-Plachky, P.2
Stiehl, A.3
-
78
-
-
12344332518
-
Signaling modulation of bile salt-induced necrosis in isolated rat hepatocytes
-
DOI 10.1093/toxsci/kfi012
-
M. Borgognone, L. M. Perez, C. L. Basiglio, J. E. Ochoa, and M. G. Roma: Signaling modulation of bile saltinduced necrosis in isolated rat hepatocytes. Toxicol. Sci. 83, 114-125 (2005). (Pubitemid 40123335)
-
(2005)
Toxicological Sciences
, vol.83
, Issue.1
, pp. 114-125
-
-
Borgognone, M.1
Perez, L.M.2
Basiglio, C.L.3
Ochoa, J.E.4
Roma, M.G.5
-
79
-
-
0027207769
-
Evidence for involvement of oxygen free radicals in bile acid toxicity to isolated rat hepatocytes
-
DOI 10.1016/0270-9139(93)90164-I
-
R. J. Sokol, M. Devereaux, R. Khandwala, and K. ÓBrien: Evidence for involvement of oxygen free radicals in bile acid toxicity to isolated rat hepatocytes. Hepatology 17, 869-881 (1993). (Pubitemid 23150097)
-
(1993)
Hepatology
, vol.17
, Issue.5
, pp. 869-881
-
-
Sokol, R.J.1
Devereaux, M.2
Khandwala, R.3
O'Brien, K.4
-
80
-
-
0036548761
-
Effect of bile acid replacement on endotoxin-induced tumor necrosis factor-alpha production in obstructive jaundice
-
S. M. Sheen-Chen, H. S. Chen, H. T. Ho, W. J. Chen, C. C. Sheen, and H. L. Eng: Effect of bile acid replacement on endotoxin-induced tumor necrosis factor-alpha production in obstructive jaundice. World J. Surg. 26, 448- 450 (2002).
-
(2002)
World J. Surg.
, vol.26
, pp. 448-450
-
-
Sheen-Chen, S.M.1
Chen, H.S.2
Ho, H.T.3
Chen, W.J.4
Sheen, C.C.5
Eng, H.L.6
-
81
-
-
0034769630
-
Free radical-triggered hepatic injury of experimental obstructive jaundice of rats involves overproduction of proinflammatory cytokines and enhanced activation of nuclear factor κB
-
T. Z. Liu, K. T. Lee, C. L. Chern, J. T. Cheng, A. Stern, and L. Y. Tsai: Free radical-triggered hepatic injury of experimental obstructive jaundice of rats involves overproduction of proinflammatory cytokines and enhanced activation of nuclear factor kappaB. Ann. Clin. Lab Sci. 31, 383-390 (2001). (Pubitemid 32988663)
-
(2001)
Annals of Clinical and Laboratory Science
, vol.31
, Issue.4
, pp. 383-390
-
-
Liu, T.-Z.1
Lee, K.-T.2
Chern, C.-L.3
Cheng, J.-T.4
Stern, A.5
Tsai, L.-Y.6
-
82
-
-
37149046027
-
Obstructive cholestasis induces TNF-α- and IL-1β-mediated periportal downregulation of Bsep and zonal regulation of Ntcp, Oatp1a4, and Oatp1b2
-
DOI 10.1152/ajpgi.00079.2007
-
M. G. Donner, S. Schumacher, U. Warskulat, J. Heinemann, and D. Haussinger: Obstructive cholestasis induces TNF-alpha- and IL-1 -mediated periportal downregulation of Bsep and zonal regulation of Ntcp, Oatp1a4, and Oatp1b2. Am. J. Physiol Gastrointest. Liver Physiol 293, G1134-G1146 (2007). (Pubitemid 350255054)
-
(2007)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.293
, Issue.6
-
-
Donner, M.G.1
Schumacher, S.2
Warskulat, U.3
Heinemann, J.4
Haussinger, D.5
-
83
-
-
0035668415
-
The expression levels of plasma membrane transporters in the cholestatic liver of patients undergoing biliary drainage and their association with the impairment of biliary secretory function
-
DOI 10.1016/S0002-9270(01)03901-6, PII S0002927001039016
-
J. Shoda, M. Kano, K. Oda, J. Kamiya, Y. Nimura, H. Suzuki, Y. Sugiyama, H. Miyazaki, T. Todoroki, S. Stengelin, W. Kramer, Y. Matsuzaki, and N. Tanaka: The expression levels of plasma membrane transporters in the cholestatic liver of patients undergoing biliary drainage and their association with the impairment of biliary secretory function. Am. J. Gastroenterol. 96, 3368-3378 (2001). (Pubitemid 34016662)
-
(2001)
American Journal of Gastroenterology
, vol.96
, Issue.12
, pp. 3368-3378
-
-
Shoda, J.1
Kano, M.2
Oda, K.3
Kamiya, J.4
Nimura, Y.5
Suzuki, H.6
Sugiyama, Y.7
Miyazaki, H.8
Todoroki, T.9
Stengelin, S.10
Kramer, W.11
Matsuzaki, Y.12
Tanaka, N.13
-
84
-
-
0242690430
-
Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis
-
DOI 10.1016/S0168-8278(03)00410-0
-
H. Kojima, A. T. Nies, J. Konig, W. Hagmann, H. Spring, M. Uemura, H. Fukui, and D. Keppler: Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis. J Hepatol 39, 693-702 (2003). (Pubitemid 37372176)
-
(2003)
Journal of Hepatology
, vol.39
, Issue.5
, pp. 693-702
-
-
Kojima, H.1
Nies, A.T.2
Konig, J.3
Hagmann, W.4
Spring, H.5
Uemura, M.6
Fukui, H.7
Keppler, D.8
-
85
-
-
34347349034
-
Clinical and pathological features of a prolonged type of acute intrahepatic cholestasis
-
DOI 10.1111/j.1872-034X.2007.00115.x
-
N. Watanabe, S. Takashimizu, S. Kojima, T. Kagawa, Y. Nishizaki, T. Mine, and S. Matsuzaki: Clinical and pathological features of a prolonged type of acute intrahepatic cholestasis. Hepatol. Res. 37, 598-607 (2007). (Pubitemid 47009245)
-
(2007)
Hepatology Research
, vol.37
, Issue.8
, pp. 598-607
-
-
Watanabe, N.1
Takashimizu, S.2
Kojima, S.3
Kagawa, T.4
Nishizaki, Y.5
Mine, T.6
Matsuzaki, S.7
-
86
-
-
38549116688
-
Disturbed colocalization of multidrug resistance protein 2 and radixin in human cholestatic liver diseases
-
DOI 10.1111/j.1440-1746.2007.05109.x
-
H. Kojima, S. Sakurai, M. Uemura, K. Kitamura, H. Kanno, Y. Nakai, and H. Fukui: Disturbed colocalization of multidrug resistance protein 2 and radixin in human cholestatic liver diseases. J. Gastroenterol. Hepatol. 23, e120-e128 (2008). (Pubitemid 352019425)
-
(2008)
Journal of Gastroenterology and Hepatology
, vol.23
, Issue.7 PART 2
-
-
Kojima, H.1
Sakurai, S.2
Uemura, M.3
Kitamura, K.4
Kanno, H.5
Nakai, Y.6
Fukui, H.7
-
87
-
-
33644839193
-
Regulation of drug transporters by PDZ adaptor proteins and nuclear receptors
-
DOI 10.1016/j.ejps.2005.11.006, PII S0928098705003362, Drug Transporters: Integration in Understanding ADME
-
Y. Kato, C. Watanabe, and A. Tsuji: Regulation of drug transporters by PDZ adaptor proteins and nuclear receptors. Eur. J. Pharm. Sci. 27, 487-500 (2006). (Pubitemid 43363340)
-
(2006)
European Journal of Pharmaceutical Sciences
, vol.27
, Issue.5
, pp. 487-500
-
-
Kato, Y.1
Watanabe, C.2
Tsuji, A.3
-
88
-
-
3543047295
-
Identification of HAX-1 as a protein that binds bile salt export protein and regulates its abundance in the apical membrane of Madin-Darby canine kidney cells
-
DOI 10.1074/jbc.M404337200
-
D. F. Ortiz, J. Moseley, G. Calderon, A. L. Swift, S. Li, and I. M. Arias: Identification of HAX-1 as a protein that binds bile salt export protein and regulates its abundance in the apical membrane of Madin-Darby canine kidney cells. J Biol. Chem 279, 32761-32770 (2004). (Pubitemid 39014735)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.31
, pp. 32761-32770
-
-
Ortiz, D.F.1
Moseley, J.2
Calderon, G.3
Swift, A.L.4
Li, S.5
Arias, I.M.6
-
89
-
-
0034636015
-
The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton
-
DOI 10.1073/pnas.97.8.4017
-
A. R. Gallagher, A. Cedzich, N. Gretz, S. Somlo, and R. Witzgall: The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton. Proc. Natl. Acad. Sci. U. S. A 97, 4017-4022 (2000). (Pubitemid 30226079)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.8
, pp. 4017-4022
-
-
Gallagher, A.R.1
Cedzich, A.2
Gretz, N.3
Somlo, S.4
Witzgall, R.5
-
90
-
-
73649091115
-
Receptor for activated C-kinase 1 regulates the cellular localization and function of ABCB4
-
Y. Ikebuchi, T. Takada, K. Ito, T. Yoshikado, N. Anzai, Y. Kanai, and H. Suzuki: Receptor for activated C-kinase 1 regulates the cellular localization and function of ABCB4. Hepatol. Res. 39, 1091-1107 (2009).
-
(2009)
Hepatol. Res.
, vol.39
, pp. 1091-1107
-
-
Ikebuchi, Y.1
Takada, T.2
Ito, K.3
Yoshikado, T.4
Anzai, N.5
Kanai, Y.6
Suzuki, H.7
-
91
-
-
0033019479
-
Changes in the localization of the rat canalicular conjugate export pump Mrp2 in phalloidin-induced cholestasis
-
D. Rost, J. Kartenbeck, and D. Keppler: Changes in the localization of the rat canalicular conjugate export pump Mrp2 in phalloidin-induced cholestasis. Hepatology 29, 814-821 (1999). (Pubitemid 29109596)
-
(1999)
Hepatology
, vol.29
, Issue.3
, pp. 814-821
-
-
Rost, D.1
Kartenbeck, J.2
Keppler, D.3
-
92
-
-
0036648878
-
Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes
-
Kikuchi S, Hata M, Fu K., Yamane Y, Matsui T, Tamura A, Yonemura S, Yamagishi H, Keppler D, Tsukita S, and Tsukita S: Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes. Nat Genet 31, 320-325 (2002).
-
(2002)
Nat Genet
, vol.31
, pp. 320-325
-
-
Kikuchi, S.1
Hata, M.2
Fu, K.3
Yamane, Y.4
Matsui, T.5
Tamura, A.6
Yonemura, S.7
Yamagishi, H.8
Keppler, D.9
Tsukita, S.10
Tsukita, S.11
-
93
-
-
33748101755
-
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes
-
DOI 10.1053/j.gastro.2006.06.013, PII S0016508506012832
-
W. Wang, C. J. Soroka, A. Mennone, C. Rahner, K. Harry, M. Pypaert, and J. L. Boyer: Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. Gastroenterology 131, 878- 884 (2006). (Pubitemid 44307066)
-
(2006)
Gastroenterology
, vol.131
, Issue.3
, pp. 878-884
-
-
Wang, W.1
Soroka, C.J.2
Mennone, A.3
Rahner, C.4
Harry, K.5
Pypaert, M.6
Boyer, J.L.7
-
94
-
-
38049161371
-
The role of radixin in altered localization of canalicular conjugate export pump Mrp2 in cholestatic rat liver
-
H. Kojima, S. Sakurai, H. Yoshiji, M. Uemura, M. Yoshikawa, and H. Fukui: The role of radixin in altered localization of canalicular conjugate export pump Mrp2 in cholestatic rat liver. Hepatol. Res. 38, 202-210 (2008).
-
(2008)
Hepatol. Res.
, vol.38
, pp. 202-210
-
-
Kojima, H.1
Sakurai, S.2
Yoshiji, H.3
Uemura, M.4
Yoshikawa, M.5
Fukui, H.6
-
95
-
-
79251479383
-
ATP-binding cassette transporter isoform C2 localizes to the apical plasma membrane via interactions with scaffolding protein
-
Y. Emi, S. Nomura, H. Yokota, and M. Sakaguchi: ATP-binding cassette transporter isoform C2 localizes to the apical plasma membrane via interactions with scaffolding protein. J. Biochem. 149, 177-189 (2011).
-
(2011)
J. Biochem.
, vol.149
, pp. 177-189
-
-
Emi, Y.1
Nomura, S.2
Yokota, H.3
Sakaguchi, M.4
-
96
-
-
24044445813
-
Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface
-
DOI 10.1074/jbc.M503969200
-
P. Wang, J. J. Wang, Y. Xiao, J. W. Murray, P. M. Novikoff, R. H. Angeletti, G. A. Orr, D. Lan, D. L. Silver, and A. W. Wolkoff: Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface. J. Biol. Chem. 280, 30143-30149 (2005). (Pubitemid 41216192)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.34
, pp. 30143-30149
-
-
Wang, P.1
Wang, J.J.2
Xiao, Y.3
Murray, J.W.4
Novikoff, P.M.5
Angeletti, R.H.6
Orr, G.A.7
Lan, D.8
Silver, D.L.9
Wolkoff, A.W.10
-
97
-
-
77953500548
-
NHERF-1 binds to Mrp2 and regulates hepatic Mrp2 expression and function
-
M. Li, W. Wang, C. J. Soroka, A. Mennone, K. Harry, E. J. Weinman, and J. L. Boyer: NHERF-1 binds to Mrp2 and regulates hepatic Mrp2 expression and function. J. Biol. Chem. 285, 19299-19307 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 19299-19307
-
-
Li, M.1
Wang, W.2
Soroka, C.J.3
Mennone, A.4
Harry, K.5
Weinman, E.J.6
Boyer, J.L.7
-
98
-
-
1642352463
-
2+-dependent protein kinase C isoforms induce cholestasis in rat liver
-
DOI 10.1074/jbc.M306242200
-
R. Kubitz, N. Saha, T. Kuhlkamp, S. Dutta, S. vom Dahl, M. Wettstein, and D. Haussinger: Ca2+-dependent protein kinase C-isoforms induce cholestasis in rat liver. J. Biol. Chem. 279, 10323-10330 (2004). (Pubitemid 38372639)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.11
, pp. 10323-10330
-
-
Kubitz, R.1
Saha, N.2
Kuhlkamp, T.3
Dutta, S.4
Vom Dahl, S.5
Wettstein, M.6
Haussinger, D.7
-
99
-
-
0034917954
-
Protein kinase C-dependent distribution of the multidrug resistance protein 2 from the canalicular to the basolateral membrane in human HepG2 cells
-
DOI 10.1053/jhep.2001.25959
-
R. Kubitz, C. Huth, M. Schmitt, A. Horbach, G. Kullak- Ublick, and D. Haussinger: Protein kinase C-dependent distribution of the multidrug resistance protein 2 from the canalicular to the basolateral membrane in human HepG2 cells. Hepatology 34, 340-350 (2001). (Pubitemid 32702347)
-
(2001)
Hepatology
, vol.34
, Issue.2
, pp. 340-350
-
-
Kubitz, R.1
Huth, C.2
Schmitt, M.3
Horbach, A.4
Kullak-Ublick, G.5
Haussinger, D.6
-
100
-
-
77955651061
-
Protein kinase C induces endocytosis of the sodium taurocholate cotransporting polypeptide
-
C. Stross, A. Helmer, K. Weissenberger, B. Gorg, V. Keitel, D. Haussinger, and R. Kubitz: Protein kinase C induces endocytosis of the sodium taurocholate cotransporting polypeptide. Am. J. Physiol Gastrointest. Liver Physiol 299, G320-G328 (2010).
-
(2010)
Am. J. Physiol Gastrointest, Liver Physiol
, vol.299
-
-
Stross, C.1
Helmer, A.2
Weissenberger, K.3
Gorg, B.4
Keitel, V.5
Haussinger, D.6
Kubitz, R.7
-
101
-
-
58149393248
-
Ca (2+)-dependent protein kinase C isoforms are critical to estradiol 17beta-D-glucuronide-induced cholestasis in the rat
-
F. A. Crocenzi, E. J. Sanchez Pozzi, M. L. Ruiz, A. E. Zucchetti, M. G. Roma, A. D. Mottino, and M. Vore: Ca (2+)-dependent protein kinase C isoforms are critical to estradiol 17beta-D-glucuronide-induced cholestasis in the rat. Hepatology 48, 1885-1895 (2008).
-
(2008)
Hepatology
, vol.48
, pp. 1885-1895
-
-
Crocenzi, F.A.1
Pozzi, E.J.S.2
Ruiz, M.L.3
Zucchetti, A.E.4
Roma, M.G.5
Mottino, A.D.6
Vore, M.7
-
102
-
-
0032985843
-
Modulation of protein kinase C by taurolithocholic acid in isolated rat hepatocytes
-
DOI 10.1002/hep.510290227
-
U. Beuers, I. Probst, C. Soroka, J. L. Boyer, G. A. Kullak-Ublick, and G. Paumgartner: Modulation of protein kinase C by taurolithocholic acid in isolated rat hepatocytes. Hepatology 29, 477-482 (1999). (Pubitemid 29088452)
-
(1999)
Hepatology
, vol.29
, Issue.2
, pp. 477-482
-
-
Beuers, U.1
Probst, I.2
Soroka, C.3
Boyer, J.L.4
Kullak-Ublick, G.-A.5
Paumgartner, G.6
-
103
-
-
0038381474
-
Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets
-
DOI 10.1074/jbc.M209898200
-
U. Beuers, G. U. Denk, C. J. Soroka, R. Wimmer, C. Rust, G. Paumgartner, and J. L. Boyer: Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3- kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets. J. Biol. Chem. 278, 17810-17818 (2003). (Pubitemid 36799385)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.20
, pp. 17810-17818
-
-
Beuers, U.1
Denk, G.U.2
Soroka, C.J.3
Wimmer, R.4
Rust, C.5
Paumgartner, G.6
Boyer, J.L.7
-
104
-
-
77957949650
-
Phosphoinositide 3- kinase/protein kinase B signaling pathway is involved in estradiol 17beta-D-glucuronide-induced cholestasis: Complementarity with classical protein kinase C
-
A. C. Boaglio, A. E. Zucchetti, E. J. Sanchez Pozzi, J. M. Pellegrino, J. E. Ochoa, A. D. Mottino, M. Vore, F. A. Crocenzi, and M. G. Roma: Phosphoinositide 3- kinase/protein kinase B signaling pathway is involved in estradiol 17beta-D-glucuronide-induced cholestasis: complementarity with classical protein kinase C. Hepatology 52, 1465-1476 (2010).
-
(2010)
Hepatology
, vol.52
, pp. 1465-1476
-
-
Boaglio, A.C.1
Zucchetti, A.E.2
Pozzi, E.J.S.3
Pellegrino, J.M.4
Ochoa, J.E.5
Mottino, A.D.6
Vore, M.7
Crocenzi, F.A.8
Roma, M.G.9
-
105
-
-
77957338101
-
Phosphatidylinositol-3-kinase p110gamma contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cells
-
S. Hohenester, A. Gates, R. Wimmer, U. Beuers, M. S. Anwer, C. Rust, and C. R. Webster: Phosphatidylinositol-3-kinase p110gamma contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cells. J. Hepatol. 53, 918-926 (2010).
-
(2010)
J. Hepatol.
, vol.53
, pp. 918-926
-
-
Hohenester, S.1
Gates, A.2
Wimmer, R.3
Beuers, U.4
Anwer, M.S.5
Rust, C.6
Webster, C.R.7
-
106
-
-
0034910937
-
MAPK activation and translocation of the bile salt export pump in rats
-
A. K. Kurz, D. Graf, M. Schmitt, and et al: Tauroursodeoxycholate-induced choleresis involves p38 (MAPK) activation and translocation of the bile salt export pump in rats. Gdastroenterology 121, 407-419 (2001). (Pubitemid 32729388)
-
(2001)
Gastroenterology
, vol.121
, Issue.2
, pp. 407-419
-
-
Kurz, A.K.1
Graf, D.2
Schmitt, M.3
Vom Dahl, S.4
HaUssinger, D.5
-
107
-
-
44649169780
-
Role of mitogen-activated protein kinases in tauroursodeoxycholic acid-induced bile formation in cholestatic rat liver
-
DOI 10.1111/j.1872-034X.2008.00321.x
-
G. U. Denk, S. Hohenester, R. Wimmer, C. Bohland, C. Rust, and U. Beuers: Role of mitogen-activated protein kinases in tauroursodeoxycholic acid-induced bile formation in cholestatic rat liver. Hepatol. Res. 38, 717-726 (2008). (Pubitemid 351784985)
-
(2008)
Hepatology Research
, vol.38
, Issue.7
, pp. 717-726
-
-
Denk, G.U.1
Hohenester, S.2
Wimmer, R.3
Bohland, C.4
Rust, C.5
Beuers, U.6
-
108
-
-
78349290358
-
Rapid downregulation of the rat glutamine transporter SNAT3 by a caveolin-dependent trafficking mechanism in Xenopus laevis oocytes
-
S. Balkrishna, A. Broer, A. Kingsland, and S. Broer: Rapid downregulation of the rat glutamine transporter SNAT3 by a caveolin-dependent trafficking mechanism in Xenopus laevis oocytes. Am. J. Physiol Cell Physiol 299, C1047-C1057 (2010).
-
(2010)
Am. J. Physiol Cell Physiol
, vol.299
-
-
Balkrishna, S.1
Broer, A.2
Kingsland, A.3
Broer, S.4
-
109
-
-
66149145265
-
ABCtransporters are localized in caveolin-1-positive and reggie-1-negative and reggie-2-negative microdomains of the canalicular membrane in rat hepatocytes
-
M. G. Ismair, S. Hausler, C. A. Stuermer, C. Guyot, P. J. Meier, J. Roth, and B. Stieger: ABCtransporters are localized in caveolin-1-positive and reggie-1-negative and reggie-2-negative microdomains of the canalicular membrane in rat hepatocytes. Hepatology 49, 1673-1682 (2009).
-
(2009)
Hepatology
, vol.49
, pp. 1673-1682
-
-
Ismair, M.G.1
Hausler, S.2
Stuermer, C.A.3
Guyot, C.4
Meier, P.J.5
Roth, J.6
Stieger, B.7
-
110
-
-
78549258081
-
LPS-induced dissociation of multidrug resistance-associated protein 2 (Mrp2) and radixin is associated with Mrp2 selective internalization in rats
-
J. Saeki, S. Sekine, and T. Horie: LPS-induced dissociation of multidrug resistance-associated protein 2 (Mrp2) and radixin is associated with Mrp2 selective internalization in rats. Biochem. Pharmacol. 81, 178- 184 (2011).
-
(2011)
Biochem. Pharmacol.
, vol.81
, pp. 178-184
-
-
Saeki, J.1
Sekine, S.2
Horie, T.3
-
111
-
-
58449089776
-
Stem cell factor induces ERM proteins phosphorylation through PI3K activation to mediate melanocyte proliferation and migration
-
S. Jeon, N. H. Kim, J. Y. Kim, and A. Y. Lee: Stem cell factor induces ERM proteins phosphorylation through PI3K activation to mediate melanocyte proliferation and migration. Pigment Cell Melanoma Res. 22, 77-85 (2009).
-
(2009)
Pigment Cell Melanoma Res
, vol.22
, pp. 77-85
-
-
Jeon, S.1
Kim, N.H.2
Kim, J.Y.3
Lee, A.Y.4
-
112
-
-
77952287580
-
NGFinduced moesin phosphorylation is mediated by the PI3K, Rac1 and Akt and required for neurite formation in PC12 cells
-
S. Jeon, J. K. Park, C. D. Bae, and J. Park: NGFinduced moesin phosphorylation is mediated by the PI3K, Rac1 and Akt and required for neurite formation in PC12 cells. Neurochem. Int. 56, 810-818 (2010).
-
(2010)
Neurochem. Int.
, vol.56
, pp. 810-818
-
-
Jeon, S.1
Park, J.K.2
Bae, C.D.3
Park, J.4
-
113
-
-
34548774634
-
High turnover of ezrin T567 phosphorylation: Conformation, activity, and cellular function
-
DOI 10.1152/ajpcell.00111.2007
-
L. Zhu, R. Zhou, S. Mettler, T. Wu, A. Abbas, J. Delaney, and J. G. Forte: High turnover of ezrin T567 phosphorylation: conformation, activity, and cellular function. Am. J. Physiol Cell Physiol 293, C874-C884 (2007). (Pubitemid 47437395)
-
(2007)
American Journal of Physiology - Cell Physiology
, vol.293
, Issue.3
-
-
Zhu, L.1
Zhou, R.2
Mettler, S.3
Wu, T.4
Abbas, A.5
Delaney, J.6
Forte, J.G.7
-
114
-
-
0035849714
-
S-Nitrosylation is emerging as a specific and fundamental posttranslational protein modification: Head-to-head comparison with Ophosphorylation
-
P. Lane, G. Hao, and S. S. Gross: S-nitrosylation is emerging as a specific and fundamental posttranslational protein modification: head-to-head comparison with Ophosphorylation. Sci. STKE. 2001, re1 (2001).
-
(2001)
Sci. STKE.
, vol.2001
-
-
Lane, P.1
Hao, G.2
Gross, S.S.3
-
115
-
-
70049083635
-
Protein S-nitrosylation in health and disease: A current perspective
-
M. W. Foster, D. T. Hess, and J. S. Stamler: Protein S-nitrosylation in health and disease: a current perspective. Trends Mol. Med. 15, 391-404 (2009).
-
(2009)
Trends Mol. Med.
, vol.15
, pp. 391-404
-
-
Foster, M.W.1
Hess, D.T.2
Stamler, J.S.3
-
116
-
-
0035040534
-
Characterization of the mouse bile salt export pump overexpressed in the baculovirus system
-
DOI 10.1053/jhep.2001.24171
-
J. Noe, B. Hagenbuch, P. J. Meier, and M. V. St Pierre: Characterization of the mouse bile salt export pump overexpressed in the baculovirus system. Hepatology 33, 1223-1231 (2001). (Pubitemid 32378223)
-
(2001)
Hepatology
, vol.33
, Issue.5
, pp. 1223-1231
-
-
Noe, J.1
Hagenbuch, B.2
Meier, P.J.3
St-Pierre, M.V.4
-
117
-
-
0010247762
-
Functional characterization of the phosphorylation of the bile salt export pump by protein kinase C
-
Abstract
-
Noe, J., Meier, P. J., and St Pierre, M. V. Functional characterization of the phosphorylation of the bile salt export pump by protein kinase C. Hepatology 34, 255A. 2001 (Abstract).
-
(2001)
Hepatology
, vol.34
-
-
Noe, J.1
Meier, P.J.2
St Pierre, M.V.3
-
118
-
-
0028107948
-
Modulation of P-glycoprotein by protein kinase Cα in a baculovirus expression system
-
S. Ahmad, A. R. Safa, and R. I. Glazer: Modulation of P-glycoprotein by protein kinase C alpha in a baculovirus expression system. Biochemistry 33, 10313-10318 (1994). (Pubitemid 24281796)
-
(1994)
Biochemistry
, vol.33
, Issue.34
, pp. 10313-10318
-
-
Ahmad, S.1
Safa, A.R.2
Glazer, R.I.3
-
119
-
-
0028904745
-
Phosphorylation of the multidrug resistance associated protein gene encoded protein P190
-
L. Ma, N. Krishnamachary, and M. S. Center: Phosphorylation of the multidrug resistance associated protein gene encoded protein P190. Biochemistry 34, 3338- 3343 (1995).
-
(1995)
Biochemistry
, vol.34
, pp. 3338-3343
-
-
Ma, L.1
Krishnamachary, N.2
Center, M.S.3
-
120
-
-
19344373339
-
Mrp2/Abcc2 transport activity is stimulated by protein kinase Cα in a baculo virus co-expression system
-
DOI 10.1016/j.lfs.2004.10.071, PII S0024320505001906
-
K. Ito, T. Wakabayashi, and T. Horie: Mrp2/Abcc2 transport activity is stimulated by protein kinase Calpha in a baculo virus co-expression system. Life Sci. 77, 539-550 (2005). (Pubitemid 40719886)
-
(2005)
Life Sciences
, vol.77
, Issue.5
, pp. 539-550
-
-
Ito, K.1
Wakabayashi, T.2
Horie, T.3
-
121
-
-
0037436789
-
C-terminal phosphorylation of MRP2 modulates its interaction with PDZ proteins
-
DOI 10.1016/S0006-291X(03)00196-7
-
T. Hegedus, T. Sessler, R. Scott, W. Thelin, E. Bakos, A. Varadi, K. Szabo, L. Homolya, S. L. Milgram, and B. Sarkadi: C-terminal phosphorylation of MRP2 modulates its interaction with PDZ proteins. Biochem. Biophys. Res. Commun. 302, 454-461 (2003). (Pubitemid 36279550)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.302
, Issue.3
, pp. 454-461
-
-
Hegedus, T.1
Sessler, T.2
Scott, R.3
Thelin, W.4
Bakos, E.5
Varadi, A.6
Szabo, K.7
Homolya, L.8
Milgram, S.L.9
Sarkadi, B.10
-
122
-
-
42249111198
-
Protein kinase Cδ mediates cyclic adenosine monophosphate- stimulated translocation of sodium taurocholate cotransporting polypeptide and multidrug resistant associated protein 2 in rat hepatocytes
-
DOI 10.1002/hep.22162
-
C. M. Schonhoff, H. Gillin, C. R. Webster, and M. S. Anwer: Protein kinase Cdelta mediates cyclic adenosine monophosphate-stimulated translocation of sodium taurocholate cotransporting polypeptide and multidrug resistant associated protein 2 in rat hepatocytes. Hepatology 47, 1309-1316 (2008). (Pubitemid 351547917)
-
(2008)
Hepatology
, vol.47
, Issue.4
, pp. 1309-1316
-
-
Schonhoff, C.M.1
Gillin, H.2
Webster, C.R.L.3
Anwer, M.S.4
-
124
-
-
14844331730
-
Silibinin prevents cholestasis-associated retrieval of the bile salt export pump, Bsep, in isolated rat hepatocyte couplets: Possible involvement of cAMP
-
DOI 10.1016/j.bcp.2005.01.009
-
F. Crocenzi, C. Basiglio, L. Pérez, M. Portesio, E. Sanchez Pozzi, and M. Roma: Silibinin prevents cholestasis-associated retrieval of the bile salt export pump, Bsep, in isolated rat hepatocyte couplets: possible involvement of cAMP. Biochem Pharmacol 69, 1113-1120 (2005). (Pubitemid 40349023)
-
(2005)
Biochemical Pharmacology
, vol.69
, Issue.7
, pp. 1113-1120
-
-
Crocenzi, F.A.1
Basiglio, C.L.2
Perez, L.M.3
Portesio, M.S.4
Sanchez Pozzi, E.J.5
Roma, M.G.6
-
125
-
-
30944462200
-
Tauroursodeoxycholic acid inserts the bile salt export pump into canalicular membranes of cholestatic rat liver
-
DOI 10.1038/labinvest.3700371, PII 3700371
-
F. Dombrowski, B. Stieger, and U. Beuers: Tauroursodeoxycholic acid inserts the bile salt export pump into canalicular membranes of cholestatic rat liver. Lab Invest 86, 166-174 (2006). (Pubitemid 43117596)
-
(2006)
Laboratory Investigation
, vol.86
, Issue.2
, pp. 166-174
-
-
Dombrowski, F.1
Stieger, B.2
Beuers, U.3
-
126
-
-
52649131370
-
Tauroursodeoxycholic acid exerts anticholestatic effects by a cooperative cPKC alpha-/PKAdependent mechanism in rat liver
-
R. Wimmer, S. Hohenester, T. Pusl, G. U. Denk, C. Rust, and U. Beuers: Tauroursodeoxycholic acid exerts anticholestatic effects by a cooperative cPKC alpha-/PKAdependent mechanism in rat liver. Gut 57, 1448-1454 (2008).
-
(2008)
Gut
, vol.57
, pp. 1448-1454
-
-
Wimmer, R.1
Hohenester, S.2
Pusl, T.3
Denk, G.U.4
Rust, C.5
Beuers, U.6
-
127
-
-
0030829597
-
Mitogen-activated protein kinases mediate the stimulation of bile acid secretion by tauroursodeoxycholate in rat liver
-
DOI 10.1053/gast.1997.v113.pm9322526
-
F. Schliess, A. K. Kurz, D. S. vom, and D. Haussinger: Mitogen-activated protein kinases mediate the stimulation of bile acid secretion by tauroursodeoxycholate in rat liver. Gastroenterology 113, 1306-1314 (1997). (Pubitemid 27418985)
-
(1997)
Gastroenterology
, vol.113
, Issue.4
, pp. 1306-1314
-
-
Schliess, F.1
Kurz, A.K.2
Vom Dahl, S.3
Haussinger, D.4
-
128
-
-
3042594002
-
Involvement of integrins and Src in tauroursodeoxycholate-induced and swelling-induced choleresis
-
DOI 10.1016/S0016-5085(03)00274-9
-
D. Haussinger, A. K. Kurz, M. Wettstein, D. Graf, D. S. vom, and F. Schliess: Involvement of integrins and Src in tauroursodeoxycholate-induced and swelling-induced choleresis. Gastroenterology 124, 1476-1487 (2003). (Pubitemid 36531820)
-
(2003)
Gastroenterology
, vol.124
, Issue.5
, pp. 1476-1487
-
-
Haussinger, D.1
Kordelia Kurz, A.2
Wettstein, M.3
Graf, D.4
Vom Dahl, S.5
Schliess, F.6
-
129
-
-
0034663645
-
Phosphoinositide 3-kinase-dependent Ras activation by tauroursodesoxycholate in rat liver
-
A. K. Kurz, C. Block, D. Graf, S. V. Dahl, F. Schliess, and D. Haussinger: Phosphoinositide 3-kinase-dependent Ras activation by tauroursodesoxycholate in rat liver. Biochem J 350 Pt 1, 207-213 (2000).
-
(2000)
Biochem J
, vol.350
, Issue.PART 1
, pp. 207-213
-
-
Kurz, A.K.1
Block, C.2
Graf, D.3
Dahl, S.V.4
Schliess, F.5
Haussinger, D.6
|