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Volumn 381, Issue 5-6, 2000, Pages 487-495

Retrieval of the mrp2 gene encoded conjugate export pump from the canalicular membrane contributes to cholestasis induced by tert-Butyl hydroperoxide and chloro-dinitrobenzene

Author keywords

ABC transporter; Cholestasis; Glutathione; Multi drug resistance; Oxidative stress

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; DIPEPTIDYL PEPTIDASE IV; GLUTATHIONE; MULTIDRUG RESISTANCE PROTEIN; POLYPEPTIDE; POTASSIUM ION; TERT BUTYL HYDROPEROXIDE;

EID: 0033947842     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2000.063     Document Type: Article
Times cited : (77)

References (38)
  • 1
    • 0019948316 scopus 로고
    • The relationship of biliary glutathione disulfide efflux and intracellular glutathione disulfide content in perfused rat liver
    • Akerboom, T.P.M., Bilzer, M., and Sies, H. (1982). The relationship of biliary glutathione disulfide efflux and intracellular glutathione disulfide content in perfused rat liver. J. Biol. Chem. 257, 4248-4252.
    • (1982) J. Biol. Chem. , vol.257 , pp. 4248-4252
    • Akerboom, T.P.M.1    Bilzer, M.2    Sies, H.3
  • 2
    • 0024446703 scopus 로고
    • Transport of glutathione, glutathione disulfide, and glutathione conjugates across the hepatocyte plasma membrane
    • Akerboom, T.P.M., and Sies, H. (1989). Transport of glutathione, glutathione disulfide, and glutathione conjugates across the hepatocyte plasma membrane. Math. Enzymol. 173, 523-534.
    • (1989) Math. Enzymol. , vol.173 , pp. 523-534
    • Akerboom, T.P.M.1    Sies, H.2
  • 3
    • 0022760449 scopus 로고
    • Cell surface glycoproteins of hepatocytes and hepatoma cells identified by monoclonal antibodies
    • Becker, A., Neumeier, R., Heidrich, C., Loch, N., Hartel, S., and Reutter, W. (1986). Cell surface glycoproteins of hepatocytes and hepatoma cells identified by monoclonal antibodies. Biol. Chem. Hoppe-Seyler 357, 681-688.
    • (1986) Biol. Chem. Hoppe-Seyler , vol.357 , pp. 681-688
    • Becker, A.1    Neumeier, R.2    Heidrich, C.3    Loch, N.4    Hartel, S.5    Reutter, W.6
  • 4
    • 0033208673 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced oxidative stress in the liver: Comparison between rat and rabbit
    • Ben-Shaul, V., Sofer, Y., Bergman, M., Zurovsky, Y., and Grossman, S. (1999). Lipopolysaccharide-induced oxidative stress in the liver: comparison between rat and rabbit. Shock 12, 288-293.
    • (1999) Shock , vol.12 , pp. 288-293
    • Ben-Shaul, V.1    Sofer, Y.2    Bergman, M.3    Zurovsky, Y.4    Grossman, S.5
  • 5
    • 0032845944 scopus 로고    scopus 로고
    • Effects of tetrabutylhydroperoxide on hepatocyte ion channels
    • Breit, S., Kolb, H.A., Häussinger, D., and Lang, F. (1999). Effects of tetrabutylhydroperoxide on hepatocyte ion channels. Cell Physiol. Biochem. 9, 133-138.
    • (1999) Cell Physiol. Biochem. , vol.9 , pp. 133-138
    • Breit, S.1    Kolb, H.A.2    Häussinger, D.3    Lang, F.4
  • 6
    • 0040761368 scopus 로고    scopus 로고
    • cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMRP, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats
    • Büchler, M., König, J., Brom, M., Kartenbeck, J., Spring, H., Horie, T., and Keppler, D. (1996). cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMRP, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats. J. Biol. Chem. 271, 15091-15098.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15091-15098
    • Büchler, M.1    König, J.2    Brom, M.3    Kartenbeck, J.4    Spring, H.5    Horie, T.6    Keppler, D.7
  • 7
    • 0032933142 scopus 로고    scopus 로고
    • Dexamethasone modulation of multidrug transporters in normal tissues
    • Demeule, M., Jodoin, J., Beaulieu, E., Brossard, M., and Beliveau, R. (1999). Dexamethasone modulation of multidrug transporters in normal tissues. FEBS Lett. 442, 208-214.
    • (1999) FEBS Lett. , vol.442 , pp. 208-214
    • Demeule, M.1    Jodoin, J.2    Beaulieu, E.3    Brossard, M.4    Beliveau, R.5
  • 8
    • 0028960244 scopus 로고
    • ATP-dependent transport systems in the canalicular membrane of the hepatocyte
    • Gatmaitan, Z.C., and Arias, I.M. (1995). ATP-dependent transport systems in the canalicular membrane of the hepatocyte. Physiol. Rev. 75, 261-275.
    • (1995) Physiol. Rev. , vol.75 , pp. 261-275
    • Gatmaitan, Z.C.1    Arias, I.M.2
  • 12
    • 0019863295 scopus 로고
    • The importance and regulation of hepatic glutathione
    • Kaplowitz, N. (1981). The importance and regulation of hepatic glutathione. Yale J. Biol. Med. 54, 497-502.
    • (1981) Yale J. Biol. Med. , vol.54 , pp. 497-502
    • Kaplowitz, N.1
  • 13
    • 0029986408 scopus 로고    scopus 로고
    • Absence of the canalicular isoform of the MRP gene-encoded conjugate export poump from the hepatocytes in Dubin-Johnson Syndrome
    • Kartenbeck, J., Leuschner, U., Mayer, R., and Keppler, D. (1996). Absence of the canalicular isoform of the MRP gene-encoded conjugate export poump from the hepatocytes in Dubin-Johnson Syndrome. Hepatology 23, 1061-1066.
    • (1996) Hepatology , vol.23 , pp. 1061-1066
    • Kartenbeck, J.1    Leuschner, U.2    Mayer, R.3    Keppler, D.4
  • 14
    • 0030817669 scopus 로고    scopus 로고
    • Induction of cMrp/cMOAT gene expression by cisplatin, 2-acetylaminofluorene, or cycloheximide in rat hepatocytes
    • Kauffmann, H.M., Keppler, D., Kartenbeck, J., and Schrenk, D. (1997). Induction of cMrp/cMOAT gene expression by cisplatin, 2-acetylaminofluorene, or cycloheximide in rat hepatocytes. Hepatology 26, 980-985.
    • (1997) Hepatology , vol.26 , pp. 980-985
    • Kauffmann, H.M.1    Keppler, D.2    Kartenbeck, J.3    Schrenk, D.4
  • 15
    • 0029849789 scopus 로고    scopus 로고
    • The canalicular conjugate export pump encoded by the cmrp/cmoat gene
    • Keppler, D., and Kartenbeck, J. (1996). The canalicular conjugate export pump encoded by the cmrp/cmoat gene. Prog. Liver Dis. 14, 55-67.
    • (1996) Prog. Liver Dis. , vol.14 , pp. 55-67
    • Keppler, D.1    Kartenbeck, J.2
  • 16
    • 0030638506 scopus 로고    scopus 로고
    • Transport across the hepatocyte canalicular membrane
    • Keppler, D., and Arias, I.M. (1997). Transport across the hepatocyte canalicular membrane. FASEB J. 11, 15-18.
    • (1997) FASEB J. , vol.11 , pp. 15-18
    • Keppler, D.1    Arias, I.M.2
  • 17
    • 0031160517 scopus 로고    scopus 로고
    • Expression and localization of the conjugate export pump encoded by the MRP2 (cMRP/ cMOAT) gene in liver
    • Keppler, D., and König, J. (1997). Expression and localization of the conjugate export pump encoded by the MRP2 (cMRP/ cMOAT) gene in liver. FASEB J. 11, 509-516.
    • (1997) FASEB J. , vol.11 , pp. 509-516
    • Keppler, D.1    König, J.2
  • 18
    • 0030731742 scopus 로고    scopus 로고
    • Osmodependent dynamic localization of the multidrug resistance protein 2 in the rat hepatocyte canalicular membrane
    • Kubitz, R., D'Urso, D., Keppler, D., and Häussinger, D. (1997). Osmodependent dynamic localization of the multidrug resistance protein 2 in the rat hepatocyte canalicular membrane. Gastroenterology 113, 1438-1442.
    • (1997) Gastroenterology , vol.113 , pp. 1438-1442
    • Kubitz, R.1    D'Urso, D.2    Keppler, D.3    Häussinger, D.4
  • 19
    • 0033564937 scopus 로고    scopus 로고
    • Dexamethasone- and osmolarity-dependent expression of the Multidrug Resistance Protein 2 in cultured rat hepatocytes
    • Kubitz, R., Warskulat, U., Schmitt, M., and Häussinger, D. (1999a). Dexamethasone- and osmolarity-dependent expression of the Multidrug Resistance Protein 2 in cultured rat hepatocytes. Biochem. J. 340, 585-591.
    • (1999) Biochem. J. , vol.340 , pp. 585-591
    • Kubitz, R.1    Warskulat, U.2    Schmitt, M.3    Häussinger, D.4
  • 20
    • 0032944048 scopus 로고    scopus 로고
    • Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone
    • Kubitz, R., Wettstein, M., Warskulat, U., and Häussinger, D. (1999b). Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone. Gastroenterology 116, 401-410.
    • (1999) Gastroenterology , vol.116 , pp. 401-410
    • Kubitz, R.1    Wettstein, M.2    Warskulat, U.3    Häussinger, D.4
  • 21
    • 0030031467 scopus 로고    scopus 로고
    • Regulation of taurocholate excretion by a hypoosmolarity-activated signal transduction pathway in rat liver
    • Noe, B., Schliess, F., Wettstein, M., Heinrich, S., and Häussinger, D. (1996). Regulation of taurocholate excretion by a hypoosmolarity-activated signal transduction pathway in rat liver. Gastroenterology 770, 858-865.
    • (1996) Gastroenterology , vol.770 , pp. 858-865
    • Noe, B.1    Schliess, F.2    Wettstein, M.3    Heinrich, S.4    Häussinger, D.5
  • 22
    • 9544233652 scopus 로고    scopus 로고
    • A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpresed in cisplatin-resistant human cancer cell lines with decreased drug accumulation
    • Okumura, K., Akiyama, S., and Kuwano, M. (1996). A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpresed in cisplatin-resistant human cancer cell lines with decreased drug accumulation. Cancer Res. 56, 4124-4129.
    • (1996) Cancer Res. , vol.56 , pp. 4124-4129
    • Okumura, K.1    Akiyama, S.2    Kuwano, M.3
  • 23
    • 0024312957 scopus 로고
    • Hepatobiliary transport of glutathione and glutathione conjugate in rats with hereditary hyperbilirubinemia
    • Oude-Elferink, R.P.J., Ottenhoff, R., Liefting, W., De Haan, J., and Jansen, P.L.M. (1989). Hepatobiliary transport of glutathione and glutathione conjugate in rats with hereditary hyperbilirubinemia. J. Clin. Invest. 84, 476-483.
    • (1989) J. Clin. Invest. , vol.84 , pp. 476-483
    • Oude-Elferink, R.P.J.1    Ottenhoff, R.2    Liefting, W.3    De Haan, J.4    Jansen, P.L.M.5
  • 26
    • 0033019479 scopus 로고    scopus 로고
    • Changes in the Localization of the rat canalicular conjugate export pump MRP2 in phalloidin-induced cholestasis
    • Rost, D., Kartenbeck, J., and Keppler, D. (1999). Changes in the Localization of the rat canalicular conjugate export pump MRP2 in phalloidin-induced cholestasis. Hepatology 29, 814-821.
    • (1999) Hepatology , vol.29 , pp. 814-821
    • Rost, D.1    Kartenbeck, J.2    Keppler, D.3
  • 27
    • 0025850732 scopus 로고
    • Regulation of fast inactivation of cloned mammalian IK(A) channels by cysteine oxidation
    • Ruppersberg, J.P., Stocker, M., Pongs, O., Heinemann, S.H., Frank, R., and Koenen, M. (1991). Regulation of fast inactivation of cloned mammalian IK(A) channels by cysteine oxidation. Nature 352, 711-714.
    • (1991) Nature , vol.352 , pp. 711-714
    • Ruppersberg, J.P.1    Stocker, M.2    Pongs, O.3    Heinemann, S.H.4    Frank, R.5    Koenen, M.6
  • 28
    • 0026709548 scopus 로고
    • Effects of anisotonic cell volume modulation on glutathione-S-conjugate release, t-butylhydroperoxide and the pentose phosphate pathway in perfused rat liver
    • Saha, N., Stoll, B., Lang, F., and Häussinger, D. (1992). Effects of anisotonic cell volume modulation on glutathione-S-conjugate release, t-butylhydroperoxide and the pentose phosphate pathway in perfused rat liver. Eur. J. Biochem. 209, 437-444.
    • (1992) Eur. J. Biochem. , vol.209 , pp. 437-444
    • Saha, N.1    Stoll, B.2    Lang, F.3    Häussinger, D.4
  • 31
    • 0016811224 scopus 로고
    • Hydroperoxide-metabolizing systems in rat liver
    • Sies, H., and Summer, K.H. (1975). Hydroperoxide-metabolizing systems in rat liver. Eur. J. Biochem. 57, 503-512.
    • (1975) Eur. J. Biochem. , vol.57 , pp. 503-512
    • Sies, H.1    Summer, K.H.2
  • 32
    • 0023030826 scopus 로고
    • Identification of ZO-1: A high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia
    • Stevenson, B.R., Siliciano, J.D., Mooseker, M.S., and Good-enough, D.A. (1986). Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J. Cell Biol. 103, 755-766.
    • (1986) J. Cell Biol. , vol.103 , pp. 755-766
    • Stevenson, B.R.1    Siliciano, J.D.2    Mooseker, M.S.3    Good-Enough, D.A.4
  • 34
    • 0014789768 scopus 로고
    • Disulfide reduction in rat liver. Evidence for the presence of non-specific nucleotide-dependent disulfide reductase and GSH-disulfide transhydrogenase activities in the high speed supernatant fraction
    • Tietze, F. (1970), Disulfide reduction in rat liver. Evidence for the presence of non-specific nucleotide-dependent disulfide reductase and GSH-disulfide transhydrogenase activities in the high speed supernatant fraction. Arch. Biochem. 138, 177-188.
    • (1970) Arch. Biochem. , vol.138 , pp. 177-188
    • Tietze, F.1
  • 35
    • 0030941401 scopus 로고    scopus 로고
    • Endotoxin impairs biliary glutathione and HCO3-excretion and blocks the choleretic effect of nitric oxide in rat liver
    • Trauner, M., Nathanson, M.H., Rydberg, S.A., Koeppel, T.A., Gartung, C., Sessa, W.C., and Boyer, J.L. (1997). Endotoxin impairs biliary glutathione and HCO3-excretion and blocks the choleretic effect of nitric oxide in rat liver. Hepatology 25, 1184-1191.
    • (1997) Hepatology , vol.25 , pp. 1184-1191
    • Trauner, M.1    Nathanson, M.H.2    Rydberg, S.A.3    Koeppel, T.A.4    Gartung, C.5    Sessa, W.C.6    Boyer, J.L.7
  • 37
    • 0018256781 scopus 로고
    • Glutathione S-conjugate formation from 1-chloro-2,4-dinitrobenzene and biliary S-conjugate excretion in the perfused rat liver
    • Wahlländer, A., and Sies, H. (1979). Glutathione S-conjugate formation from 1-chloro-2,4-dinitrobenzene and biliary S-conjugate excretion in the perfused rat liver. Eur. J. Biochem. 96, 441-446.
    • (1979) Eur. J. Biochem. , vol.96 , pp. 441-446
    • Wahlländer, A.1    Sies, H.2
  • 38
    • 0029120107 scopus 로고
    • Tumor necrosis factor α decreases hepatocyte bile salt uptake and mediates endotoxin-induced cholestasis
    • Whiting, J.F., Green, R.M., Rosenbluth, A.B., and Gollan, J.L. (1995). Tumor necrosis factor α decreases hepatocyte bile salt uptake and mediates endotoxin-induced cholestasis. Hepatology 22, 1273-1278.
    • (1995) Hepatology , vol.22 , pp. 1273-1278
    • Whiting, J.F.1    Green, R.M.2    Rosenbluth, A.B.3    Gollan, J.L.4


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