Ethacrynic-acid-induced glutathione depletion and oxidative stress in normal and Mrp2-deficient rat liver

Free Radical Biology and Medicine

Volumn 37, Issue 11, 2004, Pages 1718-1729

  Ji, Bin ^a   Ito, Kousei ^a   Sekine, Shuichi ^a   Tajima, Ai ^a   Horie, Toshiharu ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

Abcc2; EHBR; Ethacrynic acid; Free radicals; GSH; Internalization; Mrp2

Indexed keywords

ALANINE AMINOTRANSFERASE; ETACRYNIC ACID; GLUTATHIONE; MULTIDRUG RESISTANCE PROTEIN 2; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL TRANSPORT; CONTROLLED STUDY; ELIMINATION REACTION; ENZYME RELEASE; LIVER; LIVER TOXICITY; MALE; MEMBRANE PERMEABILITY; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; STATISTICAL SIGNIFICANCE;

ALANINE TRANSAMINASE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BILE CANALICULI; ETHACRYNIC ACID; GLUTATHIONE; HYPERBILIRUBINEMIA; LIPID PEROXIDATION; LIVER; MALE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 7444234246     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.08.020     Document Type: Article

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