-
1
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee, American College of Chest Physicians/Society of Critical Care Medicine
-
Bone RC et al. (1992) Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee, American College of Chest Physicians/ Society of Critical Care Medicine. Chest 101: 1644-1655
-
(1992)
Chest
, vol.101
, pp. 1644-1655
-
-
Bone, R.C.1
-
2
-
-
0043069548
-
Therapeutic approaches to innate immunity: Severe sepsis and septic shock
-
Lolis E and Bucala R (2003) Therapeutic approaches to innate immunity: severe sepsis and septic shock. Nat Rev Drug Discov 2: 635-645
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 635-645
-
-
Lolis, E.1
Bucala, R.2
-
3
-
-
0034927828
-
Hepatic response to sepsis: Interaction between coagulation and inflammatory processes
-
Dhainaut JF et al. (2001) Hepatic response to sepsis: Interaction between coagulation and inflammatory processes. Crit Care Med 29 (Suppl): S42-S47
-
(2001)
Crit Care Med
, vol.29
, Issue.SUPPL.
-
-
Dhainaut, J.F.1
-
4
-
-
0032882798
-
Inflammation-induced cholestasis
-
Trauner M et al. (1999) Inflammation-induced cholestasis. J Gastroenterol Hepatol 14: 946-959
-
(1999)
J Gastroenterol Hepatol
, vol.14
, pp. 946-959
-
-
Trauner, M.1
-
5
-
-
0031035237
-
Sepsis-associated cholestasis
-
Moseley R (1997) Sepsis-associated cholestasis. Gastroenterology 112: 302-306
-
(1997)
Gastroenterology
, vol.112
, pp. 302-306
-
-
Moseley, R.1
-
6
-
-
0037451929
-
The epidemiology of sepsis in the United States from 1979 through 2000
-
Martin GS et al. (2003) The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 348: 1546-1554
-
(2003)
N Engl J Med
, vol.348
, pp. 1546-1554
-
-
Martin, G.S.1
-
7
-
-
0035056827
-
The causes of obvious jaundice in South West Wales: Perceptions versus reality
-
Whitehead MW et al. (2001) The causes of obvious jaundice in South West Wales: Perceptions versus reality. Gut 48: 409-413
-
(2001)
Gut
, vol.48
, pp. 409-413
-
-
Whitehead, M.W.1
-
8
-
-
0029792273
-
Splanchnic ischemia and gut mucosal injury in sepsis and the multiple organ dysfunction syndrome
-
Pastores SM et al. (1996) Splanchnic ischemia and gut mucosal injury in sepsis and the multiple organ dysfunction syndrome. Am J Gastroenterol 91: 1697-1710
-
(1996)
Am J Gastroenterol
, vol.91
, pp. 1697-1710
-
-
Pastores, S.M.1
-
9
-
-
0032558588
-
Molecular pathogenesis of cholestasis
-
Trauner M et al. (1998) Molecular pathogenesis of cholestasis. N Engl J Med 339: 1217-1227
-
(1998)
N Engl J Med
, vol.339
, pp. 1217-1227
-
-
Trauner, M.1
-
10
-
-
23144443288
-
Sclerosing cholangitis following severe trauma: Description of a remarkable disease entity with emphasis on possible pathophysiologic mechanisms
-
Benninger J et al. (2005) Sclerosing cholangitis following severe trauma: Description of a remarkable disease entity with emphasis on possible pathophysiologic mechanisms. World J Gastroenterol 11: 4199-4205
-
(2005)
World J Gastroenterol
, vol.11
, pp. 4199-4205
-
-
Benninger, J.1
-
11
-
-
0038300080
-
Progressive sclerosing cholangitis after septic shock: A new variant of vanishing bile duct disorders
-
Engler S et al. (2003) Progressive sclerosing cholangitis after septic shock: A new variant of vanishing bile duct disorders. Gut 52: 688-693
-
(2003)
Gut
, vol.52
, pp. 688-693
-
-
Engler, S.1
-
12
-
-
0037379362
-
Bile salt transporters: Molecular characterization, function, and regulation
-
Trauner M and Boyer JL (2003) Bile salt transporters: Molecular characterization, function, and regulation. Physiol Rev 83: 633-671
-
(2003)
Physiol Rev
, vol.83
, pp. 633-671
-
-
Trauner, M.1
Boyer, J.L.2
-
13
-
-
0041344702
-
Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTα-OSTβ
-
Seward DJ et al. (2003) Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTα-OSTβ. J Biol Chem 278: 27473-27482
-
(2003)
J Biol Chem
, vol.278
, pp. 27473-27482
-
-
Seward, D.J.1
-
14
-
-
33646871585
-
Up-regulation of a basolateral FXR-dependent bile acid efflux transporter, OSTα-OSTβ, in cholestasis in humans and rodents
-
Boyer JL et al. (2006) Up-regulation of a basolateral FXR-dependent bile acid efflux transporter, OSTα-OSTβ, in cholestasis in humans and rodents. Am J Physiol Gastrointest Liver Physiol 290: G1124-G1130
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
-
-
Boyer, J.L.1
-
15
-
-
15444368858
-
Pathophysiology of cholangiopathies
-
Strazzabosco M et al. (2005) Pathophysiology of cholangiopathies. J Clin Gastroenterol 39 (Suppl 2): S90-S102
-
(2005)
J Clin Gastroenterol
, vol.39
, Issue.SUPPL. 2
-
-
Strazzabosco, M.1
-
16
-
-
0036623233
-
Nuclear receptor regulation of hepatic function
-
Karpen SJ (2002) Nuclear receptor regulation of hepatic function. J Hepatol 36: 832-850
-
(2002)
J Hepatol
, vol.36
, pp. 832-850
-
-
Karpen, S.J.1
-
17
-
-
9944247695
-
Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism
-
Eloranta JJ and Kullak-Ublick GA (2005) Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism. Arch Biochem Biophys 433: 397-412
-
(2005)
Arch Biochem Biophys
, vol.433
, pp. 397-412
-
-
Eloranta, J.J.1
Kullak-Ublick, G.A.2
-
18
-
-
0345732179
-
Molecular aspects of bile formation and cholestasis
-
Arrese M and Trauner M (2003) Molecular aspects of bile formation and cholestasis. Trends Mol Med 9: 558-564
-
(2003)
Trends Mol Med
, vol.9
, pp. 558-564
-
-
Arrese, M.1
Trauner, M.2
-
19
-
-
0032998834
-
Molecular regulation of hepatocellular transport systems in cholestasis
-
Trauner M et al. (1999) Molecular regulation of hepatocellular transport systems in cholestasis. J Hepatol 31: 165-178
-
(1999)
J Hepatol
, vol.31
, pp. 165-178
-
-
Trauner, M.1
-
20
-
-
1642356720
-
Sepsis and cholestasis
-
Moseley RH (2004) Sepsis and cholestasis. Clin Liver Dis 8: 83-94
-
(2004)
Clin Liver Dis
, vol.8
, pp. 83-94
-
-
Moseley, R.H.1
-
21
-
-
0030986192
-
Cellular and molecular biology of the inflamed liver
-
Crawford JM (1997) Cellular and molecular biology of the inflamed liver. Curr Opin Gastroenterol 13: 175-185
-
(1997)
Curr Opin Gastroenterol
, vol.13
, pp. 175-185
-
-
Crawford, J.M.1
-
22
-
-
0028014478
-
Endotoxin-induced cytokine gene expression and excretion in the liver
-
Luster MI et al. (1994) Endotoxin-induced cytokine gene expression and excretion in the liver. Hepatology 19: 480-488
-
(1994)
Hepatology
, vol.19
, pp. 480-488
-
-
Luster, M.I.1
-
23
-
-
0036139951
-
Interleukin-1 receptor type I gene-deficient bile duct-ligated mice are partially protected against endotoxin
-
Sewnath ME et al. (2002) Interleukin-1 receptor type I gene-deficient bile duct-ligated mice are partially protected against endotoxin. Hepatology 35: 149-158
-
(2002)
Hepatology
, vol.35
, pp. 149-158
-
-
Sewnath, M.E.1
-
24
-
-
7644234675
-
The cholangiopathies: Disorders of biliary epithelia
-
Lazaridis KN et al. (2004) The cholangiopathies: Disorders of biliary epithelia. Gastroenterology 127: 1565-1577
-
(2004)
Gastroenterology
, vol.127
, pp. 1565-1577
-
-
Lazaridis, K.N.1
-
25
-
-
0025358130
-
The acute splanchnic and peripheral tissue metabolic response to endotoxin in humans
-
Fong YM et al. (1990) The acute splanchnic and peripheral tissue metabolic response to endotoxin in humans. J Clin Invest 85: 1896-1904
-
(1990)
J Clin Invest
, vol.85
, pp. 1896-1904
-
-
Fong, Y.M.1
-
26
-
-
0028891766
-
Impaired hepatocanalicular organic anion transport in endotoxemic rats
-
Roelofsen H et al. (1995) Impaired hepatocanalicular organic anion transport in endotoxemic rats. Am J Physiol 269: G427-G434
-
(1995)
Am J Physiol
, vol.269
-
-
Roelofsen, H.1
-
27
-
-
0029120107
-
Tumor necrosis factor-alpha decreases hepatocyte bile salt uptake and mediates endotoxin-induced cholestasis
-
Whiting JF et al. (1995) Tumor necrosis factor-alpha decreases hepatocyte bile salt uptake and mediates endotoxin-induced cholestasis. Hepatology 22: 1273-1278
-
(1995)
Hepatology
, vol.22
, pp. 1273-1278
-
-
Whiting, J.F.1
-
28
-
-
0015583945
-
Effects of induced fever on sulfobromophthalein kinetics in man
-
Blaschke TF et al. (1973) Effects of induced fever on sulfobromophthalein kinetics in man. Ann Intern Med 78: 221-226
-
(1973)
Ann Intern Med
, vol.78
, pp. 221-226
-
-
Blaschke, T.F.1
-
29
-
-
0024999186
-
Tumour necrosis factor, cholestatic jaundice, and chronic liver disease
-
Jones A et al. (1990) Tumour necrosis factor, cholestatic jaundice, and chronic liver disease. Gut 31: 938-939
-
(1990)
Gut
, vol.31
, pp. 938-939
-
-
Jones, A.1
-
30
-
-
15444373825
-
Molecular regulation of hepatobiliary transport systems: Clinical implications for understanding and treating cholestasis
-
Trauner M et al. (2005) Molecular regulation of hepatobiliary transport systems: Clinical implications for understanding and treating cholestasis. J Clin Gastroenterol 39 (Suppl 2): S111-S124
-
(2005)
J Clin Gastroenterol
, vol.39
, Issue.SUPPL. 2
-
-
Trauner, M.1
-
31
-
-
0033636643
-
The hepatic microvascular responses to sepsis
-
Ring A and Stremmel W (2000) The hepatic microvascular responses to sepsis. Semin Thromb Hemost 26: 589-594
-
(2000)
Semin Thromb Hemost
, vol.26
, pp. 589-594
-
-
Ring, A.1
Stremmel, W.2
-
32
-
-
0035228428
-
Sepsis and cholestasis: Basic findings in the sinusoid and bile canaliculus
-
Hirata K et al. (2001) Sepsis and cholestasis: Basic findings in the sinusoid and bile canaliculus. J Hepatobiliary Pancreat Surg 8: 20-26
-
(2001)
J Hepatobiliary Pancreat Surg
, vol.8
, pp. 20-26
-
-
Hirata, K.1
-
33
-
-
0141920370
-
Bench-to-bedside review: Microvascular dysfunction in sepsis - hemodynamics, oxygen transport, and nitric oxide
-
Bateman RM et al. (2003) Bench-to-bedside review: Microvascular dysfunction in sepsis - hemodynamics, oxygen transport, and nitric oxide. Crit Care 7: 359-373
-
(2003)
Crit Care
, vol.7
, pp. 359-373
-
-
Bateman, R.M.1
-
34
-
-
0023268016
-
The syndrome of disappearing intrahepatic bile ducts
-
Sherlock S (1987) The syndrome of disappearing intrahepatic bile ducts. Lancet 2: 493-496
-
(1987)
Lancet
, vol.2
, pp. 493-496
-
-
Sherlock, S.1
-
35
-
-
0037370126
-
When bile ducts say NO: The good, the bad, and the ugly
-
Trauner M (2003) When bile ducts say NO: The good, the bad, and the ugly. Gastroenterology 124: 847-851
-
(2003)
Gastroenterology
, vol.124
, pp. 847-851
-
-
Trauner, M.1
-
36
-
-
0031026551
-
Nitric oxide donors stimulate bile flow and glutathione disulfide excretion independent of guanosine 3′,5′-cyclic monophosphate in the isolated perfused rat liver
-
Trauner M et al. (1997) Nitric oxide donors stimulate bile flow and glutathione disulfide excretion independent of guanosine 3′,5′-cyclic monophosphate in the isolated perfused rat liver. Hepatology 25: 263-269
-
(1997)
Hepatology
, vol.25
, pp. 263-269
-
-
Trauner, M.1
-
37
-
-
0029863171
-
cGMP stimulates bile acid-independent bile formation and biliary bicarbonate excretion
-
Myers NC et al. (1996) cGMP stimulates bile acid-independent bile formation and biliary bicarbonate excretion. Am J Physiol 270 (Pt 1): G418-G424
-
(1996)
Am J Physiol
, vol.270
, Issue.PART 1
-
-
Myers, N.C.1
-
38
-
-
0028962659
-
Nitric oxide blocks bile canalicular contraction by inhibiting inositol trisphosphate-dependent calcium mobilization
-
Dufour JF et al. (1995) Nitric oxide blocks bile canalicular contraction by inhibiting inositol trisphosphate-dependent calcium mobilization. Gastroenterology 108: 841-849
-
(1995)
Gastroenterology
, vol.108
, pp. 841-849
-
-
Dufour, J.F.1
-
39
-
-
0028834399
-
NO modulates the apicolateral cytoskeleton of isolated hepatocytes by a PKC-dependent, cGMP-independent mechanism
-
Burgstahler AD and Nathanson MH (1995) NO modulates the apicolateral cytoskeleton of isolated hepatocytes by a PKC-dependent, cGMP-independent mechanism. Am J Physiol 269 (Pt 1): G789-G799
-
(1995)
Am J Physiol
, vol.269
, Issue.PART 1
-
-
Burgstahler, A.D.1
Nathanson, M.H.2
-
40
-
-
0037370065
-
Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes
-
Spirli C et al. (2003) Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes. Gastroenterology 124: 737-753
-
(2003)
Gastroenterology
, vol.124
, pp. 737-753
-
-
Spirli, C.1
-
41
-
-
0034708264
-
Interleukin-1β suppresses retinoid transactivation of two hepatic transporter genes involved in bile formation
-
Denson LA et al. (2000) Interleukin-1β suppresses retinoid transactivation of two hepatic transporter genes involved in bile formation. J Biol Chem 275: 8835-8843
-
(2000)
J Biol Chem
, vol.275
, pp. 8835-8843
-
-
Denson, L.A.1
-
42
-
-
15844426563
-
Multiple factors regulate the rat liver basolateral sodium-dependent bile acid co-transporter gene promoter
-
Karpen SJ et al. (1996) Multiple factors regulate the rat liver basolateral sodium-dependent bile acid co-transporter gene promoter. J Biol Chem 271: 15211-15221
-
(1996)
J Biol Chem
, vol.271
, pp. 15211-15221
-
-
Karpen, S.J.1
-
43
-
-
0032524012
-
Endotoxin down-regulates rat hepatic Ntcp gene expression by decreased activity of critical transcription factors
-
Trauner M et al. (1998) Endotoxin down-regulates rat hepatic Ntcp gene expression by decreased activity of critical transcription factors. J Clin Invest 101: 2092-2100
-
(1998)
J Clin Invest
, vol.101
, pp. 2092-2100
-
-
Trauner, M.1
-
44
-
-
0036086893
-
Induction of short heterodimer partner 1 precedes downregulation of Ntcp in bile duct-ligated mice
-
Zollner G et al. (2002) Induction of short heterodimer partner 1 precedes downregulation of Ntcp in bile duct-ligated mice. Am J Physiol Gastrointest Liver Physiol 282: G184-G191
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.282
-
-
Zollner, G.1
-
45
-
-
27444441206
-
Cytokine-dependent regulation of hepatic organic anion transporter gene transactivators in mouse liver
-
Geier A et al. (2005) Cytokine-dependent regulation of hepatic organic anion transporter gene transactivators in mouse liver. Am J Physiol Gastrointest Liver Physiol 289: G831-G841
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.289
-
-
Geier, A.1
-
46
-
-
0032810191
-
Effects of LPS on transport of indocyanine green and alanine uptake in perfused rat liver
-
Lund M et al. (1999) Effects of LPS on transport of indocyanine green and alanine uptake in perfused rat liver. Am J Physiol 277 (Pt 1): G91-G100
-
(1999)
Am J Physiol
, vol.277
, Issue.PART 1
-
-
Lund, M.1
-
47
-
-
3042599451
-
Lipopolysaccharide-mediated regulation of hepatic transporter mRNA levels in rats
-
Cherrington NJ et al. (2004) Lipopolysaccharide-mediated regulation of hepatic transporter mRNA levels in rats. Drug Metab Dispos 32: 734-741
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 734-741
-
-
Cherrington, N.J.1
-
48
-
-
17744391290
-
Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases
-
Zollner G et al. (2001) Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases. Hepatology 33: 633-646
-
(2001)
Hepatology
, vol.33
, pp. 633-646
-
-
Zollner, G.1
-
49
-
-
0042766885
-
Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis
-
Geier A et al. (2003) Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis. Hepatology 38: 345-354
-
(2003)
Hepatology
, vol.38
, pp. 345-354
-
-
Geier, A.1
-
50
-
-
0033744558
-
Molecular alterations in hepatocyte transport mechanisms in acquired cholestatic liver disorders
-
Lee JM and Boyer JL (2000) Molecular alterations in hepatocyte transport mechanisms in acquired cholestatic liver disorders. Semin Liver Dis 20: 373-384
-
(2000)
Semin Liver Dis
, vol.20
, pp. 373-384
-
-
Lee, J.M.1
Boyer, J.L.2
-
51
-
-
0013138711
-
Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis
-
Zollner G et al. (2003) Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis. J Hepatol 38: 717-727
-
(2003)
J Hepatol
, vol.38
, pp. 717-727
-
-
Zollner, G.1
-
52
-
-
0033980287
-
Expression of the bile salt export pump is maintained after chronic cholestasis in the rat
-
Lee JM et al. (2000) Expression of the bile salt export pump is maintained after chronic cholestasis in the rat. Gastroenterology 118: 163-172
-
(2000)
Gastroenterology
, vol.118
, pp. 163-172
-
-
Lee, J.M.1
-
53
-
-
0030963906
-
The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis
-
Trauner M et al. (1997) The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis. Gastroenterology 113: 255-264
-
(1997)
Gastroenterology
, vol.113
, pp. 255-264
-
-
Trauner, M.1
-
54
-
-
7044223146
-
LPS-induced downregulation of MRP2 and BSEP in human liver is due to a post-transcriptional process
-
Elferink MG et al. (2004) LPS-induced downregulation of MRP2 and BSEP in human liver is due to a post-transcriptional process. Am J Physiol Gastrointest Liver Physiol 287: G1008-G1016
-
(2004)
Am J Physiol Gastrointest Liver Physiol
, vol.287
-
-
Elferink, M.G.1
-
55
-
-
0031738416
-
Up-regulation of the multidrug resistance genes Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver
-
Vos TA et al. (1998) Up-regulation of the multidrug resistance genes Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver. Hepatology 28: 1637-1644
-
(1998)
Hepatology
, vol.28
, pp. 1637-1644
-
-
Vos, T.A.1
-
56
-
-
0032902277
-
Early events in sepsis-associated cholestasis
-
Jansen PL and Muller M (1999) Early events in sepsis-associated cholestasis. Gastroenterology 116: 486-488
-
(1999)
Gastroenterology
, vol.116
, pp. 486-488
-
-
Jansen, P.L.1
Muller, M.2
-
57
-
-
0033736184
-
Short-term regulation of canalicular transport
-
Haussinger D et al. (2000) Short-term regulation of canalicular transport. Semin Liver Dis 20: 307-321
-
(2000)
Semin Liver Dis
, vol.20
, pp. 307-321
-
-
Haussinger, D.1
-
58
-
-
0032944048
-
Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone
-
Kubitz R et al. (1999) Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone. Gastroenterology 116: 401-410
-
(1999)
Gastroenterology
, vol.116
, pp. 401-410
-
-
Kubitz, R.1
-
59
-
-
27644545878
-
Degradation of the sodium taurocholate cotransporting polypeptide (NTCP) by the ubiquitin-proteasome system
-
Kuhlkamp T et al. (2005) Degradation of the sodium taurocholate cotransporting polypeptide (NTCP) by the ubiquitin-proteasome system. Biol Chem 386: 1065-1074
-
(2005)
Biol Chem
, vol.386
, pp. 1065-1074
-
-
Kuhlkamp, T.1
-
60
-
-
0347988212
-
Increased iNOS activity is essential for hepatic epithelial tight junction dysfunction in endotoxemic mice
-
Han X et al. (2004) Increased iNOS activity is essential for hepatic epithelial tight junction dysfunction in endotoxemic mice. Am J Physiol Gastrointest Liver Physiol 286: G126-G136
-
(2004)
Am J Physiol Gastrointest Liver Physiol
, vol.286
-
-
Han, X.1
-
61
-
-
0034221890
-
Interruption of hepatic gap junctional communication in the rat during inflammation induced by bacterial lipopolysaccharide
-
De Maio A et al. (2000) Interruption of hepatic gap junctional communication in the rat during inflammation induced by bacterial lipopolysaccharide. Shock 14: 53-59
-
(2000)
Shock
, vol.14
, pp. 53-59
-
-
De Maio, A.1
-
62
-
-
0036080248
-
Regulation of hepatic connexins in cholestasis: Possible involvement of Kupffer cells and inflammatory mediators
-
Gonzalez HE et al. (2002) Regulation of hepatic connexins in cholestasis: Possible involvement of Kupffer cells and inflammatory mediators. Am J Physiol Gastrointest Liver Physiol 282: G991-G1001
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.282
-
-
Gonzalez, H.E.1
-
63
-
-
0034959516
-
Proinflammatory cytokines inhibit secretion in rat bile duct epithelium
-
Spirli C et al. (2001) Proinflammatory cytokines inhibit secretion in rat bile duct epithelium. Gastroenterology 121: 156-169
-
(2001)
Gastroenterology
, vol.121
, pp. 156-169
-
-
Spirli, C.1
-
64
-
-
0035113166
-
Sclerosing cholangitis and liver cirrhosis after extrabiliary infections: Report on three cases
-
Scheppach W et al. (2001) Sclerosing cholangitis and liver cirrhosis after extrabiliary infections: Report on three cases. Crit Care Med 29: 438-441
-
(2001)
Crit Care Med
, vol.29
, pp. 438-441
-
-
Scheppach, W.1
-
66
-
-
0036788262
-
Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles
-
Fickert P et al. (2002) Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles. Gastroenterology 123: 1238-1251
-
(2002)
Gastroenterology
, vol.123
, pp. 1238-1251
-
-
Fickert, P.1
-
67
-
-
0024270262
-
Clinical significance and pathogenesis of hyperbilirubinemia associated with Staphylococcus aureus septicemia
-
Quale JM et al. (1988) Clinical significance and pathogenesis of hyperbilirubinemia associated with Staphylococcus aureus septicemia. Am J Med 85: 615-618
-
(1988)
Am J Med
, vol.85
, pp. 615-618
-
-
Quale, J.M.1
-
68
-
-
0020082099
-
Bile ductular cholestasis: An ominous histopathologic sign related to sepsis and "cholangitis lenta"
-
Lefkowitch JH (1982) Bile ductular cholestasis: An ominous histopathologic sign related to sepsis and "cholangitis lenta". Hum Pathol 13: 19-24
-
(1982)
Hum Pathol
, vol.13
, pp. 19-24
-
-
Lefkowitch, J.H.1
-
69
-
-
21344444594
-
Secondary sclerosing cholangitis: A comparison to primary sclerosing cholangitis
-
Gossard AA et al. (2005) Secondary sclerosing cholangitis: A comparison to primary sclerosing cholangitis. Am J Gastroenterol 100: 1330-1333
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 1330-1333
-
-
Gossard, A.A.1
-
70
-
-
0347353499
-
Gastrointestinal disorders of the critically ill. Shock liver
-
Strassburg CP (2003) Gastrointestinal disorders of the critically ill. Shock liver. Best Pract Res Clin Gastroenterol 17: 369-381
-
(2003)
Best Pract Res Clin Gastroenterol
, vol.17
, pp. 369-381
-
-
Strassburg, C.P.1
-
71
-
-
0034253912
-
Ischemic hepatitis: Clinical presentation and pathogenesis
-
Seeto RK et al. (2000) Ischemic hepatitis: Clinical presentation and pathogenesis. Am J Med 109: 109-113
-
(2000)
Am J Med
, vol.109
, pp. 109-113
-
-
Seeto, R.K.1
-
72
-
-
0029164260
-
Extreme serum elevations of aspartate aminotransferase
-
Johnson RD et al. (1995) Extreme serum elevations of aspartate aminotransferase. Am J Gastroenterol 90: 1244-1245
-
(1995)
Am J Gastroenterol
, vol.90
, pp. 1244-1245
-
-
Johnson, R.D.1
-
73
-
-
0344497346
-
Hypoxic hepatitis: Clinical and hemodynamic study in 142 consecutive cases
-
Henrion J et al. (2003) Hypoxic hepatitis: Clinical and hemodynamic study in 142 consecutive cases. Medicine (Baltimore) 82: 392-406
-
(2003)
Medicine (Baltimore)
, vol.82
, pp. 392-406
-
-
Henrion, J.1
-
74
-
-
0021671959
-
Ischemic hepatitis: Clinical features, diagnosis and prognosis
-
Gibson PR and Dudley FJ (1984) Ischemic hepatitis: Clinical features, diagnosis and prognosis. Aust NZ J Med 14: 822-825
-
(1984)
Aust NZ J Med
, vol.14
, pp. 822-825
-
-
Gibson, P.R.1
Dudley, F.J.2
-
75
-
-
0035829842
-
Early goal-directed therapy in the treatment of severe sepsis and septic shock
-
Rivers E et al. (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345: 1368-1377
-
(2001)
N Engl J Med
, vol.345
, pp. 1368-1377
-
-
Rivers, E.1
-
76
-
-
11444249412
-
Septic shock
-
Annane D et al. (2005) Septic shock. Lancet 365: 63-78
-
(2005)
Lancet
, vol.365
, pp. 63-78
-
-
Annane, D.1
-
77
-
-
8444238164
-
Antimicrobial therapy for patients with severe sepsis and septic shock: An evidence-based review
-
Bochud PY et al. (2004) Antimicrobial therapy for patients with severe sepsis and septic shock: An evidence-based review. Crit Care Med 32 (Suppl): S495-S512
-
(2004)
Crit Care Med
, vol.32
, Issue.SUPPL.
-
-
Bochud, P.Y.1
-
78
-
-
0036639817
-
Inhibition of transport across the hepatocyte canalicular membrane by the antibiotic fusidate
-
Bode KA et al. (2002) Inhibition of transport across the hepatocyte canalicular membrane by the antibiotic fusidate. Biochem Pharmacol 64: 151-158
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 151-158
-
-
Bode, K.A.1
-
79
-
-
0344665555
-
ABC of oral bioavailability: Transporters as gatekeepers in the gut
-
Dietrich CG et al. (2003) ABC of oral bioavailability: Transporters as gatekeepers in the gut. Gut 52: 1788-1795
-
(2003)
Gut
, vol.52
, pp. 1788-1795
-
-
Dietrich, C.G.1
-
80
-
-
0036725044
-
Ursodeoxycholic acid in cholestatic liver disease: Mechanisms of action and therapeutic use revisited
-
Paumgartner G and Beuers U (2002) Ursodeoxycholic acid in cholestatic liver disease: Mechanisms of action and therapeutic use revisited. Hepatology 36: 525-531
-
(2002)
Hepatology
, vol.36
, pp. 525-531
-
-
Paumgartner, G.1
Beuers, U.2
-
81
-
-
1642338852
-
Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease
-
Paumgartner G and Beuers U (2004) Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease. Clin Liver Dis 8: 67-81
-
(2004)
Clin Liver Dis
, vol.8
, pp. 67-81
-
-
Paumgartner, G.1
Beuers, U.2
-
82
-
-
33744920572
-
Drug insight: Mechanisms and sites of action of ursodeoxycholic acid in cholestasis
-
Beuers U (2006) Drug insight: Mechanisms and sites of action of ursodeoxycholic acid in cholestasis. Nat Clin Pract Gastroenterol Hepatol 3: 318-328
-
(2006)
Nat Clin Pract Gastroenterol Hepatol
, vol.3
, pp. 318-328
-
-
Beuers, U.1
-
83
-
-
0034949811
-
Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver
-
Fickert P et al. (2001) Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver. Gastroenterology 121: 170-183
-
(2001)
Gastroenterology
, vol.121
, pp. 170-183
-
-
Fickert, P.1
-
84
-
-
12444301770
-
Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine
-
Zollner G et al. (2003) Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine. J Hepatol 39: 480-488
-
(2003)
J Hepatol
, vol.39
, pp. 480-488
-
-
Zollner, G.1
-
85
-
-
23244465392
-
Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans
-
Marschall HU et al. (2005) Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans. Gastroenterology 129: 476-485
-
(2005)
Gastroenterology
, vol.129
, pp. 476-485
-
-
Marschall, H.U.1
-
86
-
-
0033172845
-
Review article: Mechanisms of action and therapeutic applications of ursodeoxycholic acid in chronic liver diseases
-
Trauner M and Graziadei IW (1999) Review article: Mechanisms of action and therapeutic applications of ursodeoxycholic acid in chronic liver diseases. Aliment Pharmacol Ther 13: 979-996
-
(1999)
Aliment Pharmacol Ther
, vol.13
, pp. 979-996
-
-
Trauner, M.1
Graziadei, I.W.2
-
87
-
-
8444223102
-
Use of corticosteroid therapy in patients with sepsis and septic shock: An evidence-based review
-
Keh D and Sprung CL (2004) Use of corticosteroid therapy in patients with sepsis and septic shock: An evidence-based review. Crit Care Med 32 (Suppl): S527-S533
-
(2004)
Crit Care Med
, vol.32
, Issue.SUPPL.
-
-
Keh, D.1
Sprung, C.L.2
-
88
-
-
0037151571
-
Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
-
Annane D et al. (2002) Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 288: 862-871
-
(2002)
JAMA
, vol.288
, pp. 862-871
-
-
Annane, D.1
-
89
-
-
13944260165
-
Emerging indications for albumin dialysis
-
Sen S et al. (2005) Emerging indications for albumin dialysis. Am J Gastroenterol 100: 468-475
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 468-475
-
-
Sen, S.1
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