Expression of the bile salt export pump is maintained after chronic cholestasis in the rat

Gastroenterology

Volumn 118, Issue 1, 2000, Pages 163-172

  Lee, John M ^a   Trauner, Michael ^a   Soroka, Carol J ^a   Stieger, Bruno ^b   Meier, Peter J ^b   Boyer, James L ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BILE SALT;

ANIMAL EXPERIMENT; ARTICLE; BILE SECRETION; CELL MEMBRANE TRANSPORT; CHOLESTASIS; ION TRANSPORT; LIVER CELL; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0033980287     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(00)70425-2     Document Type: Article

References (35)

1. M Trauner PJ Meier JL Boyer Molecular pathogenesis of cholestasis N Engl J Med 339 1998 1217 1227
2. M Müller PLM. Jansen Molecular aspects of hepatobiliary transport Am J Physiol 35 1997 G1285 G1303
3. JML de Vree E Jacquemin E Sturm D Cresteil PJ Bosma J Aten JF Deleuze M Desrochers M Burdelski O Bernard RPJ Oude Elferink M Hadchouel Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis Proc Natl Acad Sci USA 95 1998 282 287
4. LN Bull MJT van Eijk L Pawlikowska JA DeYoung JA Juijn M Liao LWJ Klomp N Lomri R Berger BF Scharschmidt AS Knisely RHJ Houwen NB Freimer A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis Nat Genet 18 1998 219 224
5. SS Strautnieks L Bull AS Knisely SA Kocoshis N Dahl H Arnell E Sokal K. Dahan S Childs V Ling MS Tanner AF Kagalwalla A Nemeth J Pawlowska A Baker G Mieli-Vergani NB Freimer RM Gardiner RJ Thompson A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis Nat Genet 20 1998 233 238
6. M Trauner M Arrese C Soroka M Ananthanarayanan TA Koeppel SF Schlosser FJ Suchy D Keppler JL Boyer The rat canalicular conjugate export pump (mrp 2) is down-regulated in intrahepatic and obstructive cholestasis Gastroenterology 113 1997 255 264
7. TA Vos J Guido EJ Hooiveld H Koning S Childs DKF Meijer H Moshage PLM Jansen M Muller Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver Hepatology 28 1998 1637 1644
8. RH Moseley W Wang H Takeda K Lown L Shick M Ananthanaray-anan FJ Suchy Effect of endotoxin on bile acid transport in rat liver: a potential model for sepsis-associated cholestasis Am J Physiol 271 1996 G137 G146
9. U Bolder T Huong-Thu CD Schteingart E Frick AF Hofmann Hepatocyte transport of bile acids and organic anions in endotoxemic rats: impaired uptake and secretion Gastroenterology 112 1997 214 225
10. RM Green D Beier JL Gollan Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents Gastroenterology 111 1996 193 198
11. FR Simon J Fortune M Iwahashi C Gartung A Wolkoff E Suther-land Ethinyl estradiol cholestasis involves alterations in expression of liver sinusoidal transporters Am J Physiol 34 1996 G1043 G1052
12. +/bile acid cotransporter in extrahepatic cholestasis Gastroenterology 110 1996 199 209
13. S Childs RL Yeh E Georges V Ling Identification of a sister gene to p-glycoprotein Cancer Res 55 1995 2029 2034
14. T Gerloff B Stieger B Hagenbuch J Madon L Landmann J Roth AF Hoffman PJ Meier The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver J Biol Chem 273 1998 10046 10050
15. +-independent organic anion transporter J Biol Chem 91 1994 133 137
16. C Gartung M Trauner SF Schlosser B Hagenbuch PJ Meier JL Boyer Sodium-independent uptake of bile acids is unaffected by down-regulation of an organic anion transporter (oatp) in rat liver during cholestasis produced by common bile duct ligation (CBDL) (abstr) Hepatology 24 1996 369A
17. +-independent organic anion transporting polypeptide (oatp-1) in rats with bile duct ligation J Hepatol 27 1997 1051 1056
18. T Nishida Z Gatmaitan MX Che IM Arias Rat liver canalicular membrane vesicles containing an ATP-dependent bile acid transport system Proc Natl Acad Sci USA 88 1991 6590 6594
19. M Muller T Ishikawa U Berger C Klunemann L Lucka A Schreyer C Kannicht W Reutter G Kurz D Keppler ATP-dependent transport of taurocholate across the hepatocyte canalicular membrane mediated by a 110-kDa glycoprotein binding ATP and bile salt J Biol Chem 266 1991 18920 18926
20. H Wolters F Kuipers MJH Slooff RJ Vonk Adenosine triphosphate-dependent taurocholate transport in human liver plasma membranes J Clin Invest 90 1992 2321 2326
21. R Bossard B Stieger B O'Neill G Fricker PJ Meier Ethinylestradiol treatment induces multiple canalicular membrane transport alterations in rat liver J Clin Invest 91 1993 2714 2720
22. MM Bradford A rapid and sensitive method of quantitation of microgram quantities of protein utilizing the principle of proteindye binding Anal Biochem 72 1976 248 254
23. P Chomczynski N Sacchi Single-step method isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal Biochem 162 1987 156 159
24. P Fort M Piechaczyk S El Sabrouty C Dani P Jeanteur JM Blanchard Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family Nucleic Acids Res 13 1985 1431 1442
25. H-P Buscher C Miltenberger S Macnelly W Gerok The histoauto-radiographic localization of taurocholate in rat liver after bile duct ligation J Hepatol 8 1989 181 191
26. D Schrenk TW Gant K-H Preisegger JA Silverman PA Marino SS Thorgeirsson Induction of multidrug resistance gene expression during cholestasis in rats and nonhuman primates Hepatology 17 1993 854 860
27. JP. Nolan Intestinal endotoxins as mediators of hepatic injury—an idea whose time has come again Hepatology 10 1989 887 891
28. PS Latham E Menkes MJ Phillips KN Jeejeebhoy Hyperalimentation-associated jaundice: an example of a serum factor inducing cholestasis in rats Am J Clin Nutr 41 1985 61 65
29. M Trauner M Arrese H Lee JL Boyer S Karpen Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors J Clin Invest 101 1998 2092 2100
30. H Reyes FR Simon Intrahepatic cholestasis of pregnancy: an estrogen-related disease Semin Liver Dis 13 1993 289 301
31. G-A Kullak-Ublick U Beuers C Fahney B Hagenbuch PJ Meier G Paumgartner Identification and functional characterization of the promoter region of the human organic anion transporting polypeptide gene Hepatology 26 1997 991 997
32. KN Lazaridis L Pham P Tietz RA Marinelli PC deGroen S Levine PA Dawson NF LaRusso Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter J Clin Invest 100 1997 2714 2721
33. +-dependent bile acid transporter in large but not small rat cholangiocytes Gastroenterology 113 1997 1734 1740
34. G Alpini R Lenzi L Sarkozi N Tavoloni Biliar y physiology in rats with bile ductular cell hyperplasia: evidence for a secretory function of proliferated bile ductules J Clin Invest 81 1988 569 578
35. PA Slott MH Liu N Tavoloni Origin, pattern, and mechanism of bile duct proliferation following biliar y obstruction in the rat Gastroenterology 99 1990 466 477