Cyclosporin A induced internalization of the bile salt export pump in isolated rat hepatocyte couplets

Toxicological Sciences

Volumn 71, Issue 2, 2003, Pages 276-281

  Román, Irene D ^a   Fernández Moreno, M Dolores ^a   Fueyo, Jesús A ^a   Roma, Marcelo G ^b   Coleman, Roger ^c  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Bile salt export pump (Bsep); Cyclosporin A; Cytoskeleton; F actin; Hepatocyte; Tacrolimus

Indexed keywords

BILE SALT; CARRIER PROTEIN; CHOLYLLYSINE FLUORESCEIN; CYCLOSPORIN A; DIMETHYL SULFOXIDE; F ACTIN; FLUORESCEIN DERIVATIVE; TACROLIMUS; UNCLASSIFIED DRUG;

ANIMAL CELL; CELL COUNT; CELL FUNCTION; CELL ISOLATION; CELL MEMBRANE; CELL TRANSPORT; CELL VACUOLE; CHOLESTASIS; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOSKELETON; INTRAHEPATIC BILE DUCT; LIVER CELL; MALE; NONHUMAN; PROTEIN ASSEMBLY; PROTEIN LOCALIZATION; REVIEW;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BILE ACIDS AND SALTS; BILE CANALICULI; BIOLOGICAL TRANSPORT, ACTIVE; CELLS, CULTURED; CHOLIC ACIDS; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORESCEINS; HEPATOCYTES; IMMUNOSUPPRESSIVE AGENTS; MALE; RATS; RATS, WISTAR; TACROLIMUS;

ANIMALIA;

EID: 17144473982     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/71.2.276     Document Type: Review

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