Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver

Hepatology

Volumn 33, Issue 5, 2001, Pages 1206-1216

  Beuers, Ulrich ^a   Bilzer, Manfred ^a   Chittattu, Anila ^b   Kullak Ublick, Gerd A ^a   Keppler, Dietrich ^c   Paumgartner, Gustav ^a   Dombrowski, Frank ^b  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANION; BILE ACID; BISINDOLYLMALEIMIDE; CALCIUM ION; DIMETHYL SULFOXIDE; GLUTATHIONE DERIVATIVE; ISOENZYME; MULTIDRUG RESISTANCE PROTEIN; ORGANIC COMPOUND; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; TAUROLITHOCHOLIC ACID; TAUROURSODEOXYCHOLIC ACID; URSODEOXYCHOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANION TRANSPORT; ARTICLE; BILE FLOW; BILE SECRETION; CALCIUM SIGNALING; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME LOCALIZATION; EXOCYTOSIS; IMMUNOBLOTTING; IMMUNOELECTRON MICROSCOPY; INTRAHEPATIC BILE DUCT; INTRAHEPATIC CHOLESTASIS; MALE; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0035038177     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2001.24034     Document Type: Article

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