PKCε-dependent and -independent effects of taurolithocholate on PI3K/PKB pathway and taurocholate uptake in HuH-NTCP cell line

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 297, Issue 6, 2009, Pages

  Schonhoff, Christopher M ^a   Yamazaki, Ai ^a   Hohenester, Simon ^b   Webster, Cynthia R L ^a   Bouscarel, Bernard ^c   Anwer, M Sawkat ^a  

^a TUFTS UNIVERSITY   (United States)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c GEORGE WASHINGTON UNIVERSITY   (United States)

Author keywords

Dominant negative novel protein kinase C ; Inhibition kinetics; Na+ dependent taurocholate cotransporting polypeptide; Phosphoinositide 3 kinase; PKB Akt

Indexed keywords

CYCLIC AMP; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE C EPSILON; SERINE; TAUROCHOLIC ACID; TAUROLITHOCHOLIC ACID; COTRANSPORTER; ORGANIC ANION TRANSPORTER; PRKCE PROTEIN, HUMAN; SODIUM BILE ACID COTRANSPORTER; SODIUM-BILE ACID COTRANSPORTER;

ANIMAL CELL; ARTICLE; CELL LINE; CELL STIMULATION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME INHIBITION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INCUBATION TIME; LIPID TRANSPORT; MEMBRANE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; ANIMAL; BINDING COMPETITION; CELL MEMBRANE; ENZYMOLOGY; GENETICS; KINETICS; LIVER CELL; MALE; METABOLISM; PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE; WISTAR RAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BINDING, COMPETITIVE; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CELL MEMBRANE; CYCLIC AMP; ENZYME ACTIVATION; HEPATOCYTES; HUMANS; KINETICS; MALE; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; PHOSPHORYLATION; PROTEIN KINASE C-EPSILON; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SYMPORTERS; TAUROCHOLIC ACID; TAUROLITHOCHOLIC ACID; TRANSFECTION;

EID: 72749104610     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00177.2009     Document Type: Article

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