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Volumn 22, Issue 1, 2009, Pages 77-85

Stem cell factor induces ERM proteins phosphorylation through PI3K activation to mediate melanocyte proliferation and migration

Author keywords

Ezrin radixin moesin proteins; Melanocytes; Migration; Phosphatidylinositol 3 kinase; Phosphorylation; Proliferation; Stem cell factor

Indexed keywords

ACTIN; ALANINE; EZRIN; MOESIN; PHOSPHATIDYLINOSITOL 3 KINASE; RAC1 PROTEIN; RADIXIN; STEM CELL FACTOR; THREONINE;

EID: 58449089776     PISSN: None     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2008.00519.x     Document Type: Article
Times cited : (36)

References (41)
  • 1
    • 0029086637 scopus 로고
    • Subcellular localization of moesin in dynamic filopodia, retraction fibers, and other structures involved in substrate exploration, attachment, and cell-cell contacts
    • Amieva, M.R. Furthmayr, H. (1995). Subcellular localization of moesin in dynamic filopodia, retraction fibers, and other structures involved in substrate exploration, attachment, and cell-cell contacts. Exp. Cell Res. 219, 180 196.
    • (1995) Exp. Cell Res. , vol.219 , pp. 180-196
    • Amieva, M.R.1    Furthmayr, H.2
  • 2
    • 0034492210 scopus 로고    scopus 로고
    • Actin-dependent lamellipodia formation and microtubule-dependent tail retraction control-directed cell migration
    • Ballestrem, C., Wehrle-Haller, B., Hinz, B. Imhof, B.A. (2000). Actin-dependent lamellipodia formation and microtubule-dependent tail retraction control-directed cell migration. Mol. Biol. Cell 11, 2999 3012.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 2999-3012
    • Ballestrem, C.1    Wehrle-Haller, B.2    Hinz, B.3    Imhof, B.A.4
  • 3
    • 2442513975 scopus 로고    scopus 로고
    • Nuclear ERM (ezrin, radixin, moesin) proteins: Regulation by cell density and nuclear import
    • Batchelor, C.L., Woodward, A.M. Crouch, D.H. (2004). Nuclear ERM (ezrin, radixin, moesin) proteins: regulation by cell density and nuclear import. Exp. Cell Res. 296, 208 222.
    • (2004) Exp. Cell Res. , vol.296 , pp. 208-222
    • Batchelor, C.L.1    Woodward, A.M.2    Crouch, D.H.3
  • 4
    • 0028821843 scopus 로고
    • Ezrin oligomers are major cytoskeletal components of placental microvilli: A proposal for their involvement in cortical morphogenesis
    • Berryman, M., Gary, R. Bretscher, A. (1995). Ezrin oligomers are major cytoskeletal components of placental microvilli: a proposal for their involvement in cortical morphogenesis. J. Cell Biol. 131, 1231 1242.
    • (1995) J. Cell Biol. , vol.131 , pp. 1231-1242
    • Berryman, M.1    Gary, R.2    Bretscher, A.3
  • 5
    • 0026039464 scopus 로고
    • Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis
    • Blume-Jensen, P., Claesson-Welsh, L., Siegbahn, A., Zsebo, K.M., Westermark, B. Heldin, C.H. (1991). Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis. EMBO J. 10, 4121 4128.
    • (1991) EMBO J. , vol.10 , pp. 4121-4128
    • Blume-Jensen, P.1    Claesson-Welsh, L.2    Siegbahn, A.3    Zsebo, K.M.4    Westermark, B.5    Heldin, C.H.6
  • 6
    • 0024542907 scopus 로고
    • Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor
    • Bretscher, A. (1989). Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor. J. Cell Biol. 108, 921 930.
    • (1989) J. Cell Biol. , vol.108 , pp. 921-930
    • Bretscher, A.1
  • 9
    • 0037352170 scopus 로고    scopus 로고
    • Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: A target for cancer chemotherapy
    • Chang, F., Lee, J.T., Navolanic, P.M., Steelman, L.S., Shelton, J.G., Blalock, W.L., Franklin, R.A. McCubrey, J.A. (2003). Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. Leukemia 17, 590 603.
    • (2003) Leukemia , vol.17 , pp. 590-603
    • Chang, F.1    Lee, J.T.2    Navolanic, P.M.3    Steelman, L.S.4    Shelton, J.G.5    Blalock, W.L.6    Franklin, R.A.7    McCubrey, J.A.8
  • 10
    • 0027485538 scopus 로고
    • Multiple cytokines induce the tyrosine phosphorylation of Shc and its association with Grb2 in hemopoietic cells
    • Cutler, R.L., Liu, L., Damen, J.E. Krystal, G. (1993). Multiple cytokines induce the tyrosine phosphorylation of Shc and its association with Grb2 in hemopoietic cells. J. Biol. Chem. 268, 21463 21465.
    • (1993) J. Biol. Chem. , vol.268 , pp. 21463-21465
    • Cutler, R.L.1    Liu, L.2    Damen, J.E.3    Krystal, G.4
  • 13
    • 0032550225 scopus 로고    scopus 로고
    • Association of the myosin-binding subunit of myosin phosphatase and moesin: Dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase
    • Fukata, Y., Kimura, K., Oshiro, N., Saya, H., Matsuura, Y. Kaibuchi, K. (1998). Association of the myosin-binding subunit of myosin phosphatase and moesin: dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase. J. Cell Biol. 141, 409 418.
    • (1998) J. Cell Biol. , vol.141 , pp. 409-418
    • Fukata, Y.1    Kimura, K.2    Oshiro, N.3    Saya, H.4    Matsuura, Y.5    Kaibuchi, K.6
  • 14
    • 19544362066 scopus 로고    scopus 로고
    • Adhesion, migration and communication in melanocytes and melanoma
    • Haass, N.K., Smalley, K.S., Li, L. Herlyn, M. (2005). Adhesion, migration and communication in melanocytes and melanoma. Pigment Cell Res. 18, 150 159.
    • (2005) Pigment Cell Res. , vol.18 , pp. 150-159
    • Haass, N.K.1    Smalley, K.S.2    Li, L.3    Herlyn, M.4
  • 15
    • 9244219575 scopus 로고    scopus 로고
    • The melanocortin receptor-1 gene but not the proopiomelanocortin gene is expressed in melanoblasts and contributes their differentiation in the mouse skin
    • Hirobe, T., Takeuchi, S. Hotta, E. (2004). The melanocortin receptor-1 gene but not the proopiomelanocortin gene is expressed in melanoblasts and contributes their differentiation in the mouse skin. Pigment Cell Res. 17, 627 635.
    • (2004) Pigment Cell Res. , vol.17 , pp. 627-635
    • Hirobe, T.1    Takeuchi, S.2    Hotta, E.3
  • 17
    • 1842473620 scopus 로고    scopus 로고
    • Autocrine and paracrine regulation of melanocytes in human skin and in pigmentary disorders
    • Imokawa, G. (2004). Autocrine and paracrine regulation of melanocytes in human skin and in pigmentary disorders. Pigment Cell Res. 17, 96 110.
    • (2004) Pigment Cell Res. , vol.17 , pp. 96-110
    • Imokawa, G.1
  • 18
    • 0029670689 scopus 로고    scopus 로고
    • Ignalling mechanisms of endothelin-induced mitogenesis and melanogenesis in human melanocytes
    • Imokawa, G., Yada, Y. Kimura, M. (1996). ignalling mechanisms of endothelin-induced mitogenesis and melanogenesis in human melanocytes. Biochem. J. 314, 305 312.
    • (1996) Biochem. J. , vol.314 , pp. 305-312
    • Imokawa, G.1    Yada, Y.2    Kimura, M.3
  • 19
    • 0037053360 scopus 로고    scopus 로고
    • RhoA and Rho kinase-dependent phosphorylation of moesin at Thr-558 in hippocampal neuronal cells by glutamate
    • Jeon, S., Kim, S., Park, J.B., Suh, P.G., Kim, Y.S., Bae, C.D. Park, J. (2002). RhoA and Rho kinase-dependent phosphorylation of moesin at Thr-558 in hippocampal neuronal cells by glutamate. J. Biol. Chem. 277, 16576 16584.
    • (2002) J. Biol. Chem. , vol.277 , pp. 16576-16584
    • Jeon, S.1    Kim, S.2    Park, J.B.3    Suh, P.G.4    Kim, Y.S.5    Bae, C.D.6    Park, J.7
  • 20
    • 16844380712 scopus 로고    scopus 로고
    • Chloride conductance is required for the protein kinase A and Rac1-dependent phosphorylation of moesin at Thr-558 by KCl in PC12 cells
    • Jeon, S., Kim, S., Kim, E., Lee, J.E., Kim, S.J., Juhnn, Y.S., Kim, Y.S., Bae, C.D. Park, J. (2005). Chloride conductance is required for the protein kinase A and Rac1-dependent phosphorylation of moesin at Thr-558 by KCl in PC12 cells. J. Biol. Chem. 280, 12181 12189.
    • (2005) J. Biol. Chem. , vol.280 , pp. 12181-12189
    • Jeon, S.1    Kim, S.2    Kim, E.3    Lee, J.E.4    Kim, S.J.5    Juhnn, Y.S.6    Kim, Y.S.7    Bae, C.D.8    Park, J.9
  • 22
    • 0028986034 scopus 로고
    • The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts
    • Kozma, R., Ahmed, S., Best, A. Lim, L. (1995). The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts. Mol. Cell. Biol. 15, 1942 1952.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1942-1952
    • Kozma, R.1    Ahmed, S.2    Best, A.3    Lim, L.4
  • 23
    • 0026760578 scopus 로고
    • Identification of the two major epidermal growth factor-induced tyrosine phosphorylation sites in the microvillar core protein ezrin
    • Krieg, J. Hunter, T. (1992). Identification of the two major epidermal growth factor-induced tyrosine phosphorylation sites in the microvillar core protein ezrin. J. Biol. Chem. 267, 19258 19265.
    • (1992) J. Biol. Chem. , vol.267 , pp. 19258-19265
    • Krieg, J.1    Hunter, T.2
  • 24
    • 0031034574 scopus 로고    scopus 로고
    • Antiapoptotic signalling by the insulin-like growth factor i receptor, phosphatidylinositol 3-kinase, and Akt
    • Kulik, G., Klippel, A. Weber, M.J. (1997). Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol. Cell. Biol. 17, 1595 1606.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1595-1606
    • Kulik, G.1    Klippel, A.2    Weber, M.J.3
  • 25
  • 26
    • 5044240701 scopus 로고    scopus 로고
    • PI3K mediates protection against TRAIL-induced apoptosis in primary human melanocytes
    • Larribere, L., Khaled, M., Tartare-Deckert, S. et al. (2004). PI3K mediates protection against TRAIL-induced apoptosis in primary human melanocytes. Cell Death Differ. 11, 1084 1091.
    • (2004) Cell Death Differ. , vol.11 , pp. 1084-1091
    • Larribere, L.1    Khaled, M.2    Tartare-Deckert, S.3
  • 27
    • 0033619142 scopus 로고    scopus 로고
    • Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction
    • Lennartsson, J., Blume-Jensen, P., Hermanson, M., Pontén, E., Carlberg, M. Rönnstrand, L. (1999). Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction. Oncogene 18, 5546 5553.
    • (1999) Oncogene , vol.18 , pp. 5546-5553
    • Lennartsson, J.1    Blume-Jensen, P.2    Hermanson, M.3    Pontén, E.4    Carlberg, M.5    Rönnstrand, L.6
  • 28
    • 0028041512 scopus 로고
    • Multiple cytokines stimulate the binding of a common 145-kilodalton protein to Shc at the Grb2 recognition site of Shc
    • Liu, L., Damen, J.E., Cutler, R.L. Krystal, G. (1994). Multiple cytokines stimulate the binding of a common 145-kilodalton protein to Shc at the Grb2 recognition site of Shc. Mol. Cell Biol. 14, 6926 6935.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 6926-6935
    • Liu, L.1    Damen, J.E.2    Cutler, R.L.3    Krystal, G.4
  • 29
    • 0032498528 scopus 로고    scopus 로고
    • Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association
    • Matsui, T., Maeda, M., Doi, Y., Yonemura, S., Amano, M., Kaibuchi, K., Tsukita, S.T. sukita, S. (1998). Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association. J. Cell Biol. 9, 647 657.
    • (1998) J. Cell Biol. , vol.9 , pp. 647-657
    • Matsui, T.1    Maeda, M.2    Doi, Y.3    Yonemura, S.4    Amano, M.5    Kaibuchi, K.6    Tsukita, S.T.7    Sukita, S.8
  • 30
    • 0028306229 scopus 로고
    • Terminal differentiation and senescence in the human melanocyte: Repression of tyrosine-phosphorylation of the extracellular signal-regulated kinase 2 selectively defines the two phenotypes
    • Medrano, E.E., Yang, F., Boissy, R., Farooqui, J., Shah, V., Matsumoto, K., Nordlund, J.J. Park, H.Y. (1994). Terminal differentiation and senescence in the human melanocyte: repression of tyrosine-phosphorylation of the extracellular signal-regulated kinase 2 selectively defines the two phenotypes. Mol. Biol. Cell. 5, 497 509.
    • (1994) Mol. Biol. Cell. , vol.5 , pp. 497-509
    • Medrano, E.E.1    Yang, F.2    Boissy, R.3    Farooqui, J.4    Shah, V.5    Matsumoto, K.6    Nordlund, J.J.7    Park, H.Y.8
  • 32
    • 0037057801 scopus 로고    scopus 로고
    • The nuclear phosphoinositide 3-kinase/AKT pathway: A new second messenger system
    • Neri, L.M., Borgatti, P., Capitani, S. Martelli, A.M. (2002). The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system. Biochim. Biophys. Acta 1584, 73 80.
    • (2002) Biochim. Biophys. Acta , vol.1584 , pp. 73-80
    • Neri, L.M.1    Borgatti, P.2    Capitani, S.3    Martelli, A.M.4
  • 33
    • 0028837170 scopus 로고
    • Activation of the small GTP-binding proteins rho and rac by growth factor receptors
    • Nobes, C.D., Hawkins, P., Stephens, L. Hall, A. (1995). Activation of the small GTP-binding proteins rho and rac by growth factor receptors. J. Cell Sci. 108, 225 233.
    • (1995) J. Cell Sci. , vol.108 , pp. 225-233
    • Nobes, C.D.1    Hawkins, P.2    Stephens, L.3    Hall, A.4
  • 34
    • 0032567361 scopus 로고    scopus 로고
    • Phosphorylation of moesin by rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures
    • Oshiro, N., Fukata, Y. Kaibuchi, K. (1998). Phosphorylation of moesin by rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures. J. Biol. Chem. 273, 34663 34666.
    • (1998) J. Biol. Chem. , vol.273 , pp. 34663-34666
    • Oshiro, N.1    Fukata, Y.2    Kaibuchi, K.3
  • 35
    • 0032571406 scopus 로고    scopus 로고
    • Protein kinase C-theta phosphorylation of moesin in the actin-binding sequence
    • Pietromonaco, S.F., Simons, P.C., Altman, A. Elias, L. (1998). Protein kinase C-theta phosphorylation of moesin in the actin-binding sequence. J. Biol. Chem. 273, 7594 7603.
    • (1998) J. Biol. Chem. , vol.273 , pp. 7594-7603
    • Pietromonaco, S.F.1    Simons, P.C.2    Altman, A.3    Elias, L.4
  • 36
    • 0026778133 scopus 로고
    • The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
    • Ridley, A.J. Hall, A. (1992). The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70, 389 399.
    • (1992) Cell , vol.70 , pp. 389-399
    • Ridley, A.J.1    Hall, A.2
  • 37
    • 0026654125 scopus 로고
    • The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
    • Ridley, A.J., Paterson, H.F., Johnston, C.L., Diekmann, D. Hall, A. (1992). The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70, 401 410.
    • (1992) Cell , vol.70 , pp. 401-410
    • Ridley, A.J.1    Paterson, H.F.2    Johnston, C.L.3    Diekmann, D.4    Hall, A.5
  • 38
    • 34247380314 scopus 로고    scopus 로고
    • Involvement of Fyn kinase in Kit and integrin-mediated Rac activation, cytoskeletal reorganization, and chemotaxis of mast cells
    • Samayawardhena, L.A., Kapur, R. Craig, A.W. (2007). Involvement of Fyn kinase in Kit and integrin-mediated Rac activation, cytoskeletal reorganization, and chemotaxis of mast cells. Blood 109, 3679 3686.
    • (2007) Blood , vol.109 , pp. 3679-3686
    • Samayawardhena, L.A.1    Kapur, R.2    Craig, A.W.3
  • 39
    • 14844299368 scopus 로고    scopus 로고
    • Src-dependent ezrin phosphorylation in adhesion-mediated signaling
    • Srivastava, J., Elliott, B.E., Louvard, D. Arpin, M. (2005). Src-dependent ezrin phosphorylation in adhesion-mediated signaling. Mol. Biol. Cell 16, 1481 1490.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 1481-1490
    • Srivastava, J.1    Elliott, B.E.2    Louvard, D.3    Arpin, M.4
  • 40
    • 0032476674 scopus 로고    scopus 로고
    • Kit signaling through PI 3-kinase and Src kinase pathways: An essential role for Rac1 and JNK activation in mast cell proliferation
    • Timokhina, I., Kissel, H., Stella, G. Besmer, P. (1998). Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation. EMBO J. 17, 6250 6262.
    • (1998) EMBO J. , vol.17 , pp. 6250-6262
    • Timokhina, I.1    Kissel, H.2    Stella, G.3    Besmer, P.4


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