Phosphoinositide 3-Kinase/Protein Kinase B Signaling Pathway Is Involved in Estradiol 17β-D-Glucuronide–Induced Cholestasis: Complementarity with Classical Protein Kinase C

Hepatology

Volumn 52, Issue 4, 2010, Pages 1465-1476

  Boaglio, Andrea C ^a   Zucchetti, Andrés E ^a   Sánchez Pozzi, Enrique J ^a   Pellegrino, José M ^a   Ochoa, Justina Elena ^a   Mottino, Aldo D ^a   Vore, Mary ^b   Crocenzi, Fernando A ^a   Roma, Marcelo G ^a  

^a Universidad Nacional de Río Cuarto Consejo Nacional de Investigaciones Científicas y Técnicas   (Argentina)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; ABC TRANSPORTER; ABCB11 PROTEIN, RAT; ANDROSTANE DERIVATIVE; CARBAZOLE DERIVATIVE; COLCHICINE; DRUG DERIVATIVE; ESTRADIOL; ESTRADIOL 17 BETA GLUCURONIDE; ESTRADIOL-17 BETA-GLUCURONIDE; GLUTATHIONE; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2; PHOSPHATIDYLINOSITOL KINASE; PROTEIN KINASE B; PROTEIN KINASE C; TAUROCHOLIC ACID; WORTMANNIN;

ANIMAL; ARTICLE; CHEMICALLY INDUCED DISORDER; CHOLESTASIS; DRUG ANTAGONISM; DRUG EFFECT; ENDOCYTOSIS; HEPATOBILIARY SYSTEM; IN VITRO STUDY; INTRAHEPATIC BILE DUCT; MALE; METABOLISM; MICROTUBULE; PERFUSION; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; WISTAR RAT;

1-PHOSPHATIDYLINOSITOL 4-KINASE; ANDROSTADIENES; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BILE CANALICULI; BILIARY TRACT; CARBAZOLES; CHOLESTASIS; COLCHICINE; ENDOCYTOSIS; ESTRADIOL; GLUTATHIONE; MALE; MICROTUBULES; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PERFUSION; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; TAUROCHOLIC ACID;

MLCS; MLOWN;

EID: 77957949650     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.23846     Document Type: Article

References (34)

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